4 Works

Organoids from patient biopsy samples can predict the response of BC patients to neoadjuvant chemotherapy

Dan Shu, Meiying Shen, Kang Li, Xiaojian Han, Han Li, Zhaofu Tan, Yu Wang, Yang Peng, Zhenrong Tang, Chi Qu, Aishun Jin & Shengchun Liu
Neoadjuvant chemotherapy has been widely used in locally advanced and inflammatory breast cancer. Generally, complete pathological response after neoadjuvant chemotherapy treatment predicts survival. Studies have shown that patient-derived organoids can be used in cancer research and drug development. Therefore, we aimed to generate a living organoid biobank from biopsy samples to predict the response of patients to neoadjuvant chemotherapy. We generated a living organoid biobank from locally advanced breast cancer patients receiving neoadjuvant chemotherapy. When...

Organoids from patient biopsy samples can predict the response of BC patients to neoadjuvant chemotherapy

Dan Shu, Meiying Shen, Kang Li, Xiaojian Han, Han Li, Zhaofu Tan, Yu Wang, Yang Peng, Zhenrong Tang, Chi Qu, Aishun Jin & Shengchun Liu
Neoadjuvant chemotherapy has been widely used in locally advanced and inflammatory breast cancer. Generally, complete pathological response after neoadjuvant chemotherapy treatment predicts survival. Studies have shown that patient-derived organoids can be used in cancer research and drug development. Therefore, we aimed to generate a living organoid biobank from biopsy samples to predict the response of patients to neoadjuvant chemotherapy. We generated a living organoid biobank from locally advanced breast cancer patients receiving neoadjuvant chemotherapy. When...

Additional file 1 of The important role of NLRP6 inflammasome in Pasteurella multocida infection

Xingping Wu, Zheng Zeng, Hongliang Tian, Lianci Peng, Dongyi Xu, Yu Wang, Chao Ye, Yuanyi Peng & Rendong Fang
Additional file 1: NLRP6 is involved in the recruitment of macrophages and neutrophils in pulmonary infection with P. multocida. WT and Nlrp6-/- mice were intranasally infected with 20 µL P. multocida (1000 CFU) and the same volume of sterilized PBS were used as control. Flow cytometry was used to analyze the recruitment of neutrophils and macrophages after 24 h infection. (A, B, E, F). Aseptic PBS infection group (control group). (C, D, G, H). P....

Additional file 1 of The important role of NLRP6 inflammasome in Pasteurella multocida infection

Xingping Wu, Zheng Zeng, Hongliang Tian, Lianci Peng, Dongyi Xu, Yu Wang, Chao Ye, Yuanyi Peng & Rendong Fang
Additional file 1: NLRP6 is involved in the recruitment of macrophages and neutrophils in pulmonary infection with P. multocida. WT and Nlrp6-/- mice were intranasally infected with 20 µL P. multocida (1000 CFU) and the same volume of sterilized PBS were used as control. Flow cytometry was used to analyze the recruitment of neutrophils and macrophages after 24 h infection. (A, B, E, F). Aseptic PBS infection group (control group). (C, D, G, H). P....

Registration Year

  • 2022
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Resource Types

  • Image
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Affiliations

  • Tianjin Agricultural University
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  • Hainan Medical University
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  • West China Hospital of Sichuan University
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  • Zhejiang University
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  • Xuan Wu Hospital of the Capital Medical University
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  • Wenzhou Medical University
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  • Livestock Improvement Corporation
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  • Fudan University
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  • Capital Medical University
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  • Tianjin Medical University Cancer Institute and Hospital
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