8 Works

The effect of amiloride in decreasing albuminuria in patients with diabetic kidney diseases: a prospective, crossover, open-label study

Ruizhao Li, Zhiyong Xie, Li Zhang, Ying Huang, Jianchao Ma, Wei Dong, Zhilian Li, Yuanhan Chen, Huaban Liang, Yanhua Wu, Xingchen Zhao, Wenjian Wang, Zhiming Ye, Shuangxin Liu, Wei Shi & Xinling Liang
Diabetic kidney diseases (DKD) were the leading cause of End-stage renal diseases worldwide. Albuminuria was a target for treatment in DKD and decreasing albuminuria was particularly important for improving its prognosis. However, there is still a lack of specific treatment for DKD. We conducted a prospective, crossover, open-label study to investigate the effect of amiloride in patients with DKD. Safety and efficacy were assessed by monitoring urine protein creatinine ratio(uPCR), urinary albumin creatinine ratio (uACR),...

The effect of amiloride in decreasing albuminuria in patients with diabetic kidney diseases: a prospective, crossover, open-label study

Ruizhao Li, Zhiyong Xie, Li Zhang, Ying Huang, Jianchao Ma, Wei Dong, Zhilian Li, Yuanhan Chen, Huaban Liang, Yanhua Wu, Xingchen Zhao, Wenjian Wang, Zhiming Ye, Shuangxin Liu, Wei Shi & Xinling Liang
Diabetic kidney diseases (DKD) were the leading cause of End-stage renal diseases worldwide. Albuminuria was a target for treatment in DKD and decreasing albuminuria was particularly important for improving its prognosis. However, there is still a lack of specific treatment for DKD. We conducted a prospective, crossover, open-label study to investigate the effect of amiloride in patients with DKD. Safety and efficacy were assessed by monitoring urine protein creatinine ratio(uPCR), urinary albumin creatinine ratio (uACR),...

Additional file 3 of JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Qin Lin, Zheng Chen, Wei Shi, Zeheng Lv, Xiaoping Wan & Kun Gao
Additional file 3: Fig. S2. JAK1 knockdown elevates the expression of HIF downstream genes in SPEC-2 cells.

Additional file 2 of JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Qin Lin, Zheng Chen, Wei Shi, Zeheng Lv, Xiaoping Wan & Kun Gao
Additional file 2: Fig. S1. JAK1 overexpression suppresses EC cell growth and migration.

Additional file 4 of JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Qin Lin, Zheng Chen, Wei Shi, Zeheng Lv, Xiaoping Wan & Kun Gao
Additional file 4: Fig. S3. JAK1 overexpression downregulates the expression of HIF downstream genes in Ishikawa cells.

Additional file 3 of JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Qin Lin, Zheng Chen, Wei Shi, Zeheng Lv, Xiaoping Wan & Kun Gao
Additional file 3: Fig. S2. JAK1 knockdown elevates the expression of HIF downstream genes in SPEC-2 cells.

Additional file 2 of JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Qin Lin, Zheng Chen, Wei Shi, Zeheng Lv, Xiaoping Wan & Kun Gao
Additional file 2: Fig. S1. JAK1 overexpression suppresses EC cell growth and migration.

Additional file 4 of JAK1 inactivation promotes proliferation and migration of endometrial cancer cells via upregulating the hypoxia-inducible factor signaling pathway

Qin Lin, Zheng Chen, Wei Shi, Zeheng Lv, Xiaoping Wan & Kun Gao
Additional file 4: Fig. S3. JAK1 overexpression downregulates the expression of HIF downstream genes in Ishikawa cells.

Registration Year

  • 2022
    6
  • 2021
    2

Resource Types

  • Image
    8

Affiliations

  • West China Hospital of Sichuan University
    8
  • Huazhong University of Science and Technology
    8
  • Walter and Eliza Hall Institute of Medical Research
    8
  • University of Melbourne
    8
  • ShenZhen People‚Äôs Hospital
    8
  • La Trobe University
    8
  • Southern Medical University
    8
  • Tongji University
    7
  • Guangdong Academy of Medical Sciences
    7
  • China Earthquake Administration
    7