2,712 Works

Additional file 3 of TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC

Bufu Tang, Yajie Wang, Jinyu Zhu, Jingjing Song, Shiji Fang, Qiaoyou Weng, Yang Yang, Jianfei Tu, Zhongwei Zhao, Minjiang Chen, Min Xu, Weiqian Chen & Jiansong Ji
Additional file 3: Figure S3. The predictive performance of NDRG1 in predicting the TACE response of HCC patients. A Expression characteristics of NDRG1 in TACE responders and nonresponders. B The ROC curve showing the predictive reliability of NDRG1 in predicting the TACE response of HCC patients. C consistency analysis of NDRG1 expression in predicting the TACE response of HCC patients. D DCA of NDRG1 in predicting the TACE response of HCC patients.

Additional file 2 of TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC

Bufu Tang, Yajie Wang, Jinyu Zhu, Jingjing Song, Shiji Fang, Qiaoyou Weng, Yang Yang, Jianfei Tu, Zhongwei Zhao, Minjiang Chen, Min Xu, Weiqian Chen & Jiansong Ji
Additional file 2: Figure S2. A-L Correlation of the TRscore of the HCC-TACE cohort in the GSE14520 cohort with the sensitivity to common molecularly targeted drugs.

Additional file 1 of Changes in the salivary metabolome in patients with chronic erosive gastritis

Shaowei Liu, Shixiong Zhang, Haoyu Chen, Pingping Zhou, Tianxiao Yang, Jingjing Lv, Huixia Li & Yangang Wang
Supplementary Material 1

Additional file 2 of Changes in the salivary metabolome in patients with chronic erosive gastritis

Shaowei Liu, Shixiong Zhang, Haoyu Chen, Pingping Zhou, Tianxiao Yang, Jingjing Lv, Huixia Li & Yangang Wang
Supplementary Material 2

Additional file 1 of Changes in the salivary metabolome in patients with chronic erosive gastritis

Shaowei Liu, Shixiong Zhang, Haoyu Chen, Pingping Zhou, Tianxiao Yang, Jingjing Lv, Huixia Li & Yangang Wang
Supplementary Material 1

Additional file 6 of Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats

Zhu Wang, Qiong Deng, Yanli Gu, Min Li, Yeda Chen, Jieyan Wang, Ying Zhang, Jianwen Zhang, Qiyi Hu, Shenping Zhang, Wei Chen, Zhenhua Chen, Jiaying Li, Xisheng Wang & Hui Liang
Additional file 6: Figure S6. Expression features of distinct markers in BI subclusters.

Additional file 7 of Integrated single-nucleus sequencing and spatial architecture analysis identified distinct injured-proximal tubular types in calculi rats

Zhu Wang, Qiong Deng, Yanli Gu, Min Li, Yeda Chen, Jieyan Wang, Ying Zhang, Jianwen Zhang, Qiyi Hu, Shenping Zhang, Wei Chen, Zhenhua Chen, Jiaying Li, Xisheng Wang & Hui Liang
Additional file 7: Figure S7. KEEG enrichments of DEGs in the BI clusters in kidneys of rats with calculi.

Mitochondrial genome of a typical cavefish of Sinocyclocheilus anatirostris

Xinrui Zhao, Changting Lan, Jing Yu, Jiajun Zhou, Xueli Lu, Ning Xiao, Huaiqing Deng & Jiang Zhou
Sinocyclocheilus anatirostris Lin and Luo, 1986 is a member of the endemic Chinese genus Sinocyclocheilus Fang, 1936, living in dark caves with absence of eyes and scales. Muscle tissue was collected from cavefish samples from Guangxi, China, and complete mitogenome was sequenced. This is the first report of the mitogenome of S. anatirostris. This mitogenome consists of 13 protein-coding genes (PCGs), two rRNA genes (12S rRNA and 16S rRNA), 22 tRNA genes, a control region...

Additional file 1 of An entomopathogenic fungus exploits its host humoral antibacterial immunity to minimize bacterial competition in the hemolymph

Jia-Lin Wang, Jing Sun, Ya-Jing Song, Huan-Huan Zheng, Gui-Jie Wang, Wen-Xia Luo, Li Li & Xu-Sheng Liu
Additional file 1: Figure S1. Compromised peritrophic matrix (PM) integrity in M. rileyi-infected larvae. (A) The PM integrity was impaired in the larvae injected with blastospores. Paraffin section of the midgut from larvae at 12 hpi of blastospores or PBS was checked.The green arrow indicates intact PM, while the red arrow points to fragmented PM. Scale bar = 400 μm. (B) Comparison of differentially expressed genes (DEGs) in the midgut of blastospore-injected (MB) and PBS-injected...

sj-tif-1-tag-10.1177_17562848231170945 – Supplemental material for Development and validation of a deep learning-based approach to predict the Mayo endoscopic score of ulcerative colitis

Jing Qi, Guangcong Ruan, Yi Ping, Zhifeng Xiao, Kaijun Liu, Yi Cheng, Rongbei Liu, Bingqiang Zhang, Min Zhi, Junrong Chen, Fang Xiao, Tingting Zhao, Jiaxing Li, Zhou Zhang, Yuxin Zou, Qian Cao, Yongjian Nian & Yanling Wei
Supplemental material, sj-tif-1-tag-10.1177_17562848231170945 for Development and validation of a deep learning-based approach to predict the Mayo endoscopic score of ulcerative colitis by Jing Qi, Guangcong Ruan, Yi Ping, Zhifeng Xiao, Kaijun Liu, Yi Cheng, Rongbei Liu, Bingqiang Zhang, Min Zhi, Junrong Chen, Fang Xiao, Tingting Zhao, Jiaxing Li, Zhou Zhang, Yuxin Zou, Qian Cao, Yongjian Nian and Yanling Wei in Therapeutic Advances in Gastroenterology

sj-tif-2-tag-10.1177_17562848231170945 – Supplemental material for Development and validation of a deep learning-based approach to predict the Mayo endoscopic score of ulcerative colitis

Jing Qi, Guangcong Ruan, Yi Ping, Zhifeng Xiao, Kaijun Liu, Yi Cheng, Rongbei Liu, Bingqiang Zhang, Min Zhi, Junrong Chen, Fang Xiao, Tingting Zhao, Jiaxing Li, Zhou Zhang, Yuxin Zou, Qian Cao, Yongjian Nian & Yanling Wei
Supplemental material, sj-tif-2-tag-10.1177_17562848231170945 for Development and validation of a deep learning-based approach to predict the Mayo endoscopic score of ulcerative colitis by Jing Qi, Guangcong Ruan, Yi Ping, Zhifeng Xiao, Kaijun Liu, Yi Cheng, Rongbei Liu, Bingqiang Zhang, Min Zhi, Junrong Chen, Fang Xiao, Tingting Zhao, Jiaxing Li, Zhou Zhang, Yuxin Zou, Qian Cao, Yongjian Nian and Yanling Wei in Therapeutic Advances in Gastroenterology

Additional file 3 of ISG15 targets glycosylated PD-L1 and promotes its degradation to enhance antitumor immune effects in lung adenocarcinoma

Tongyuan Qu, Wenshuai Zhang, Chenhui Yan, Danyang Ren, Yalei Wang, Yuhong Guo, Qianru Guo, Jinpeng Wang, Liren Liu, Lei Han, Lingmei Li, Qiujuan Huang, Lu Cao, Zhaoxiang Ye, Bin Zhang, Qiang Zhao & Wenfeng Cao
Additional file 3: Fig. S3. Typical images of ISG15 and lymphocyte IHC staining. A, B, Typical IHC images of ISG15 and lymphocytes other than CD3+and CD4+ T cells.

Additional file 1 of ISG15 targets glycosylated PD-L1 and promotes its degradation to enhance antitumor immune effects in lung adenocarcinoma

Tongyuan Qu, Wenshuai Zhang, Chenhui Yan, Danyang Ren, Yalei Wang, Yuhong Guo, Qianru Guo, Jinpeng Wang, Liren Liu, Lei Han, Lingmei Li, Qiujuan Huang, Lu Cao, Zhaoxiang Ye, Bin Zhang, Qiang Zhao & Wenfeng Cao
Additional file 1: Fig. S1. The relationship between pathological types of lung adenocarcinoma and T cell lymphocytes. A–F, The relationship between the expression of CD3+, CD4+, CD8+, CD45RO+, CD45RA+ and Foxp3+ T lymphocytes in five pathological types of lung adenocarcinoma.

Additional file 2 of Risk of lymph node metastasis and feasibility of endoscopic submucosal dissection in undifferentiated-type early gastric cancer

Pengyue Zhang, Tingting Xu, Hui Feng, Zhen Zhu, Jingjing Wang & Yalei Wang
Supplementary Material 2

Additional file 13 of Breast metastatic tumors in lung can be substituted by lung-derived malignant cells transformed by alternative splicing H19 lncRNA

Jin Biao Xu, Jun Cao, Jin Xia, Ying Zhu, Yi He, Ming Guo Cao, Bing Mu Fang, Jean Paul Thiery & Wu Zhou
Additional file 13. Figure S9: Investigation in clinical samples. A H&Eor IHCfor Sftpc were applied onto the slices of lung metastasis from MBC patients. Arrows show the Sftpc positive cells. left panel: scar bar, 320um; magnification, 1×. middle panel: scar bar, 80um; magnification, 4×. right panel: scar bar, 40um; magnification, 10×. B The RNA expression of H19-L, H19-S or Myc in lung metastasesand their paired adjacent tissuesof 28 MBC patients were analyzed by qRT-PCR. The...

Additional file 7 of Breast metastatic tumors in lung can be substituted by lung-derived malignant cells transformed by alternative splicing H19 lncRNA

Jin Biao Xu, Jun Cao, Jin Xia, Ying Zhu, Yi He, Ming Guo Cao, Bing Mu Fang, Jean Paul Thiery & Wu Zhou
Additional file 7. Figure S6: AT2 cells from the new generated tumor are malignant. MPG-ST-iDTR miceat 16 weeks were injected with 100 ng diphtheria toxinevery 8 h for 7 consecutive days. After DT injection for 2 weeks, AT2 cells among the lung metastasis were FACS-sorted and subcutaneously transplantedinto syngeneic wild-type mice. H&E and immunohistochemistry for adenocarcinoma markerswere applied after growth for 18 weeks. Magnification, 4×, 10×and 20×. n=number of mice.

sj-png-1-tct-10.1177_15330338231175735 - Supplemental material for The Differential Diagnostic Value of Radiomics Signatures Between Single-Nodule Pulmonary Metastases and Second Primary Lung Cancer in Patients with Colorectal Cancer

Yu Yu, Jiaqing Tan, Yi Yang, Bin Zhang, Xiaodong Yao, Shibiao Sang & Shengming Deng
Supplemental material, sj-png-1-tct-10.1177_15330338231175735 for The Differential Diagnostic Value of Radiomics Signatures Between Single-Nodule Pulmonary Metastases and Second Primary Lung Cancer in Patients with Colorectal Cancer by Yu Yu, Jiaqing Tan, Yi Yang, Bin Zhang, Xiaodong Yao, Shibiao Sang and Shengming Deng in Technology in Cancer Research & Treatment

sj-tif-1-npx-10.1177_1934578X231176916 - Supplemental material for Effect and Mechanism of Schizandrin A in the Treatment of Liver Cancer Using Network Pharmacology, Molecular Docking, and Target Validation

Xiaohui Wang, Lin Zhou, Tao Zhang, Hui Chen, Xinhao Song & Feng Wang
Supplemental material, sj-tif-1-npx-10.1177_1934578X231176916 for Effect and Mechanism of Schizandrin A in the Treatment of Liver Cancer Using Network Pharmacology, Molecular Docking, and Target Validation by Xiaohui Wang, Lin Zhou, Tao Zhang, Hui Chen, Xinhao Song and Feng Wang in Natural Product Communications

Additional file 3 of Differences in the global exposure, mortality and disability of low bone mineral density between men and women: the underestimated burden in men

Binxiang Zhu, Shian Hu, Jianfeng Guo, Zijian Dong, Yimin Dong & Feng Li
Additional file 3.

Additional file 1 of Differences in the global exposure, mortality and disability of low bone mineral density between men and women: the underestimated burden in men

Binxiang Zhu, Shian Hu, Jianfeng Guo, Zijian Dong, Yimin Dong & Feng Li
Additional file 1.

Co-treatment with miR-21-5p inhibitor and Aurora kinase inhibitor reversine suppresses breast cancer progression by targeting sprouty RTK signaling antagonist 2

Yue Zhang, Yaoyi Wang, Jun Xue, Wanping Liang, Zhisheng Zhang, Xiuming Yang, Zhifei Qiao, Yang Jiang, Junping Wang, Xuchen Cao & Peng Chen
Numerous studies have reported the regulatory effects of miR-21-5p and reversine in human breast cancer (HBC). However, the mechanism of reversine and miR-21-5p has not been fully investigated in HBC. The aim of the current study was to assess the mechanism of action of reversine, with or without miR-21-5p, in HBC progression. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and Western blot results confirmed the upregulation of miR-21-5p and downregulation of sprouty RTK signaling antagonist 2...

Additional file 5 of LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers

Manting Ma, Bolin Cai, Zhen Zhou, Shaofen Kong, Jing Zhang, Haiping Xu, Xiquan Zhang & Qinghua Nie
Additional file 4: Figure S3. Interference of LncRNA-TBP inhibits fatty acid oxidation in skeletal muscle. (A-F) Relative LncRNA-TBP expression (n = 4) (A), relative mtDNA content (n = 4) (B), relative fatty acid β-oxidation rate (n = 4) (C), relative FFA and TG content (n = 4) (D), relative mRNA (n = 6) (E) and protein (n = 3) (F) expression levels of fatty acid oxidation or synthesis related-genes in gastrocnemius with LncRNA-TBP interference in...

Additional file 5 of LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers

Manting Ma, Bolin Cai, Zhen Zhou, Shaofen Kong, Jing Zhang, Haiping Xu, Xiquan Zhang & Qinghua Nie
Additional file 4: Figure S3. Interference of LncRNA-TBP inhibits fatty acid oxidation in skeletal muscle. (A-F) Relative LncRNA-TBP expression (n = 4) (A), relative mtDNA content (n = 4) (B), relative fatty acid β-oxidation rate (n = 4) (C), relative FFA and TG content (n = 4) (D), relative mRNA (n = 6) (E) and protein (n = 3) (F) expression levels of fatty acid oxidation or synthesis related-genes in gastrocnemius with LncRNA-TBP interference in...

Additional file 6 of LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers

Manting Ma, Bolin Cai, Zhen Zhou, Shaofen Kong, Jing Zhang, Haiping Xu, Xiquan Zhang & Qinghua Nie
Additional file 5: Figure S4. Interference of LncRNA-TBP activates fast-twitch muscle phenotype and reduces muscle hypertrophy. (A-N) relative enzymes activity of LDH and SDH (n = 4) (A), Relative glycogen content (n = 5) (B), relative mRNA expression levels of glycogenolytic and glycolytic genes (n = 6) (C), relative mRNA expression levels of several fast-/slow-twitch myofiber genes (n = 6) (D), immunohistochemistry analysis of MYH1A/MYH7B (n = 3) (E), MYH1A/MYH7B protein content (n = 8)...

Additional file 10 of LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers

Manting Ma, Bolin Cai, Zhen Zhou, Shaofen Kong, Jing Zhang, Haiping Xu, Xiquan Zhang & Qinghua Nie
Additional file 9: Figure S8. The expression and location analysis of TBP. (A) Relative TBP expression during the proliferation and differentiation of CPM isolated from XH chicken (n = 4). (B) Subcellular location of TBP protein annotated by UniProt Knowledgebase ( https://www.uniprot.org/ ). In panels (A), results are presented as mean ± SEM.

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