Additional file 7. The effect of splenic denervation on vessels of EAM mice. A. HE staining for spleen histological signs of EAM mice and EAM+SDN mice. B. Representative images of whole spleen sections of EAM mice and EAM+SDN mice. Blue, nuclear staining. Green, CD31 is a sensitive and specific marker for vascular endothelial injury (especially white arrow). EAM: Experimental Autoimmune Myocarditis; SDN: Splenic Denervation; HE: hematoxylin and eosin.

Additional file 5: Fig. S4. The abundance of Sphingomonas in the gut of the IMI-S and IMI-R strains and SXYC, SDBZ, XJSW and HBHS field populations. The bars with lowercase letters (a, b, c) are significantly different according to one-way ANOVA, followed by Tukey's multiple comparison test (P< 0.05).

Additional file 2: Fig. S2. The activation of IL-6/STAT3 pathway promotes the CSC-like phenotypes of TNBC cells.

Additional file 1: Fig. S1. The proportion of CD8+ T cells was unchanged in thymus after anti-CD8α treatment..

Additional file 2: Figure S1. IRAK-M expression is inducible by multiple stimuli in A549 cells. IRAK-M protein expression at 0, 6, 12, 24 h after (a) IL-1β (1 ng/ml), (b) TNF-α (10 ng/ml), (c) IL-33 (100 ng/ml) and (d) HDM (10 μg/ml) exposure. IRAK-M protein expression was normalized to GAPDH. Values are expressed as mean ± SEM (n = 3). *P < 0.05.

Additional file 3: Fig. S2. Uncropped WB images of Arg1, iNOS, TH and β-actin. A: WB result of Arg1 (36 kDa). B: WB result of iNOS (110-130 kDa, 65-70 kDa). C: WB result of β-actin (43 kDa). D: WB result of TH (57 kDa). E: WB result of β-actin (43 kDa). Dashed lines indicated where they were cropped to make Fig.6C and Fig.4J.

Additional file 1: Fig. S1. Experimental flow chart.

Supplemental material, sj-tiff-2-jhc-10.1369_00221554231161693 for Multiplex Immunofluorescence Image Quality Checking Using DAPI Channel–referenced Evaluation by Jun Jiang, Raymond Moore, Clarissa E. Jordan, Ruifeng Guo, Rachel L. Maus, Hongfang Liu, Ellen Goode, Svetomir N. Markovic and Chen Wang in Journal of Histochemistry & Cytochemistry

Supplemental material, sj-jpg-1-jcb-10.1177_0271678X231165606 for Microvascular dysfunction associated with unfavorable venous outflow in acute ischemic stroke patients by Xiaoshuang Li, Liping Lin, Jian Zhang, Yuhua Fan, Shihui Xing, Li Jiang, Zhiyun Yang, Jing Zhao and Jingjing Li in Journal of Cerebral Blood Flow & Metabolism

Additional file 1: Fig. S1. Mouse lung fibrosis model. A MMP19 overexpression in mice lungs was achieved by intratracheal injection of AAV, followed by intratracheal injection of PBS or BLM at 4 days, and mice were sacrificed at 18 days. B In vivo imaging system was performed to detect the transfection efficiency of AAV. C Fluorescence microscope was performed to detect the transfection efficiency of AAV. D Western blot was performed to detect the transfection...

Additional file 3: Fig. S3. Expression profile analysis of Vimentin and VE-cadherin in endothelial cells of mice treated with Saline and BLM. A-B Expression profile of Vimentin and VE-cadherin in endothelial cells of mice treated with Saline and BLM. C-D Expression relevance between MMP19, Vimentin and VE-cadherin in endothelial cells of mice treated with Saline and BLM.

Additional file 2: Figure S2. The ROC curves of Resnet101 and VGG-19.

Additional file 1. Figure S1: Within-sample diversity by community type. Notched boxplot of diversity index of samples grouped in community type (color indicated in legend). Within-sample diversity was estimated using Shannon diversity index using Phyloseq R package [102]. The top and bottom of the box are the lower and upper quartiles, and the band near the middle of the box represents the median. Box width is proportional to the square root of the size of...

Additional file 3. Figure S3: Community diversity analyses using weighted UniFrac principal coordinates analysis (PCoA) analyses using QIIME2 (v2019.10) [117]. Each symbol represents a sample colored by its different anatomical sites. The scatterplot is of principal coordinate 1 (PC1) plotting against principal coordinate 2 (PC2), and the percentage of the variation described by the plotted principal coordinates in indicated on the axes.

Additional file 4: Figure S4. No significant difference was observed in AS lesions, cholesterol, triglycerides between ABCB5+ MSC treated and untreated mice. 7 days post DLFA, blood and aorta samples from mice were taken. A representative HE stained sections of the aorta from the A control group and B ABCB5+ MSC treated mice. A1 and B1 displays atherosclerotic vessel wall while A2 and B2 displays normal vessel wall (scale bar is 50 μm in Figure...

Additional file 1. Differential clinical outcomes of ACC patients in the two different clusters. Heatmap was generated to validate the expression levels of DEGs between ACC and normal samples in the TCGA cohort. ACC adrenocortical carcinoma.

Additional file 1. Differential clinical outcomes of ACC patients in the two different clusters. Heatmap was generated to validate the expression levels of DEGs between ACC and normal samples in the TCGA cohort. ACC adrenocortical carcinoma.

Additional file 1: Figure S1. Expression patterns for different types of cells in hGfap-Cre-mediated knockout of Ggps1. A Representative fluorescence images for co-staining of Pax6/Ggpps in the cerebellum. Brain sections at P4 and P7 were used. Whereas there were abundant Pax6+/Ggpps+ cells in control mice, there were little Pax6+/Ggpps+ cells in Ggps1 cKO mice. B Enlarged images for the boxed areas in A. C Representative fluorescence images for co-staining of NeuN/Ggpps in the cerebellum. Whereas...

Additional file 2. Unprocessed images of Western blot in Figure 1.

Additional file 4: Figure S1. The m6A sites of TMBIM6 predicted by RMBase v2.0.

Additional file 5: Figure S2. TMBIM6 was the potential target of METLL3 by M6A2Target.

Additional file 2: Supplementary figure 2. OC classification based on these differentially expressed genes. (A) Consensus clustering tracking plot for k = 2 to 9. (B) Consensus matrix for k = 2, in line with which 420 OC patients were grouped into two clusters. (C) Kaplan‒Meier overall survival curves for patients in Clusters 1 and 2 (samples with a survival time of more than ten years and less than one month were excluded). (D) Heatmap...

Additional file 3: Supplementary figure 3. Consensus clustering of OC. (A) The cumulative distribution function (CDF) is displayed for k = 2–9. (B) The curve of the relative change in the area under the CDF for k = 2 to 9. (C-I) Consensus clustering matrix for k = 3 to 9.

Additional file 4: Supplementary figure 4. Forest plot of 50 differentially expressed GTs using univariate Cox regression analysis based on the data from the TCGA.

Additional file 2: Figure S2. The Cobb angle, sagittal parameters and LL before (A,C and E) and after (B,D and F) operation of case 23.