4 Works

Liquiritigenin exerts the anti-cancer role in oral cancer via inducing autophagy-related apoptosis through PI3K/AKT/mTOR pathway inhibition in vitro and in vivo

Yingchen Ji, Weiwei Hu, Yan Jin, Huiming Yu & Jin Fang
Figure published via Taylor & Francis
Operative treatment on oral cancer greatly damages the chewing and language function of the patient, we aim to find better solution with fewer side effects. The anti-tumor effects of Liquiritigenin (LQ) have been explored in kinds of cancers, but not in oral cancer. In this study, our purpose is to reveal the effects of LQ on oral cancer and the associated mechanism. Cell proliferation was examined through 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and 5-Ethynyl-2ʹ- deoxyuridine (EDU)...
1 citation
No usage information was reported.
https://doi.org/10.6084/m9.figshare.16577658.v1 Cite

Nucleoporin 160 (NUP160) inhibition alleviates diabetic nephropathy by activating autophagy

Jiayong Xie, Ying Yuan, Gang Yao, Zhi Chen, Wenjuan Yu & Qiang Zhu
Figure published via Taylor & Francis
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Autophagy was reported to be related to the pathogenesis of DN. This research investigated the function of the Nucleoporin 160 (Nup160) gene in regulating autophagy in DN. A mouse model of DN was established through an intraperitoneal injection of streptozotocin (STZ). Normal rat kidney tubular epithelial cells (NRK-52E) were treated with high glucose to induce DN in vitro. Real-time quantitative polymerase chain reaction...
1 citation
No usage information was reported.
https://doi.org/10.6084/m9.figshare.16635212 Cite

Nucleoporin 160 (NUP160) inhibition alleviates diabetic nephropathy by activating autophagy

Jiayong Xie, Ying Yuan, Gang Yao, Zhi Chen, Wenjuan Yu & Qiang Zhu
Figure published via Taylor & Francis
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Autophagy was reported to be related to the pathogenesis of DN. This research investigated the function of the Nucleoporin 160 (Nup160) gene in regulating autophagy in DN. A mouse model of DN was established through an intraperitoneal injection of streptozotocin (STZ). Normal rat kidney tubular epithelial cells (NRK-52E) were treated with high glucose to induce DN in vitro. Real-time quantitative polymerase chain reaction...
1 citation
No usage information was reported.
https://doi.org/10.6084/m9.figshare.16635212.v1 Cite

Liquiritigenin exerts the anti-cancer role in oral cancer via inducing autophagy-related apoptosis through PI3K/AKT/mTOR pathway inhibition in vitro and in vivo

Yingchen Ji, Weiwei Hu, Yan Jin, Huiming Yu & Jin Fang
Figure published via Taylor & Francis
Operative treatment on oral cancer greatly damages the chewing and language function of the patient, we aim to find better solution with fewer side effects. The anti-tumor effects of Liquiritigenin (LQ) have been explored in kinds of cancers, but not in oral cancer. In this study, our purpose is to reveal the effects of LQ on oral cancer and the associated mechanism. Cell proliferation was examined through 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and 5-Ethynyl-2ʹ- deoxyuridine (EDU)...
1 citation
No usage information was reported.
https://doi.org/10.6084/m9.figshare.16577658 Cite

Registration Year

  • 2021
    4

Resource Types

  • Image
    4

Affiliations

  • First Affiliated Hospital of Chongqing Medical University
    4
  • Zhejiang University
    2
  • Fudan University Shanghai Cancer Center
    2
  • Fudan University
    2
  • Tianjin Medical University Cancer Institute and Hospital
    2
  • University of California, San Diego
    2
  • Zhongnan Hospital of Wuhan University
    2
  • Shanghai Medical College of Fudan University
    2
  • Shandong University
    2
  • Shanghai Jiao Tong University
    2

About DataCite

Services

Resources

Community