Additional file 5: Figure S5. Overexpression of CDK1 enhanced protein stabilities of UBE2C and AURKA/B. a Expressions of UBE2C and AURKA/B in SW-13_NC and SW-13_CDK1 cells after treatment with CHX (100 μmol/L) at 0, 1, 3, 9, 12 h. b Relative expression of UBE2C, AURKA c and AURKB d in SW-13_NC and SW-13_CDK1 cells after treatment with CHX. Statistical differences were assessed by two-way ANOVA. *P < 0.05, **P < 0.01, ***P < 0.001.

Additional file 5: Figure S5. Overexpression of CDK1 enhanced protein stabilities of UBE2C and AURKA/B. a Expressions of UBE2C and AURKA/B in SW-13_NC and SW-13_CDK1 cells after treatment with CHX (100 μmol/L) at 0, 1, 3, 9, 12 h. b Relative expression of UBE2C, AURKA c and AURKB d in SW-13_NC and SW-13_CDK1 cells after treatment with CHX. Statistical differences were assessed by two-way ANOVA. *P < 0.05, **P < 0.01, ***P < 0.001.

Additional file 6: Figure S6. Silencing the markers of apoptosis or pyroptosis could not rescue CurE-mediated cell death. a Transfection efficacy of knockdown caspase 3 expression in SW-13 cells. b Transfection efficacy of knockdown caspase 3 expression in NCI-H295R cells. c Transfection efficacy of knockdown GSDMD expression in SW-13 cells. b Transfection efficacy of knockdown GSDMD expression in NCI-H295R cells. e Silencing caspase 3 increased necrotic cells triggered by CurE in SW-13 cells. f Silencing...

Supplemental material, sj-tif-1-jet-10.1177_15266028231160101 for Deep Learning Prediction for Distal Aortic Remodeling After Thoracic Endovascular Aortic Repair in Stanford Type B Aortic Dissection by Min Zhou, Xiaoyuan Luo, Xia Wang, Tianchen Xie, Yonggang Wang, Zhenyu Shi, Manning Wang and Weiguo Fu in Journal of Endovascular Therapy

Coagulation factors participates in the inflammatory cascade, known to play a crucial role in the development of acute kidney injury (AKI). Thus, it’s likely that some factors may be associated with AKI. Among them, low levels of fibrinogen and antithrombin III (ATIII) activity have been proved to increase mortality in patients with sepsis. Moreover, they are also reported to be associated with higher incidence of AKI. However, the association between coagulation parameters, especially fibrinogen and...

Additional file 1: Figure S1. The Cobb angle, sagittal parameters and LL before (A,C and E) and after (B,D and F) operation of case 9.

Additional file 7: Supplement Figure 7. The Bland–Altman analysis for assessing inter-observer variability of myocardial work index of eighteen segments.

Additional file 8: Supplement Figure 8. The Bland–Altman analysis for assessing inter-observer variability of myocardial work efficiency of eighteen segments.

Additional file 2.

Additional file 5: Figure S1. Drug metabolism pathway and apoptosis pathway of DEGs.

Additional file 2: Supplementary Figure 2. The dynamic curve of pre-op GH levels and post-op GH levels in 180 min-OGTT. The pre-op GH levels decreased from 4.82 to 2.65μg/mL; The post-op GH levels were successfully suppressed from 7.62to 0.4μg/mL (basal GH, 7.62μg/mL; maximal suppression, 0.4μg/mL)

Additional file 3: Supplementary Figure 3. Double immunohistochemistry and immunofluorescence staining of a Plurimorphous plurihormonal Pit-1 positive adenoma. A. TSH and GH double immunofluorescence staining, anti-GH is stained with Cy3 (red), anti-TSH with Actin-Tracker Green-488 (green), and nuclei with DAPI (blue). Original magnification × 630. B. TSH and GH double immunohistochemistry staining, GH is marked yellow, TSH is marked red, original magnification × 200. C. GH and PRL double immunofluorescence staining, anti-GH is stained with...

Additional file 3. Comparison of survival prognosis by surgical approach (invasion depth). Invasion depth: Inner 1/3 (A: DFS; B: OS); Middle 1/3 (C: DFS; D: OS); Deep 1/3 (E: DFS; F: OS). ORH, open radical hysterectomy; MLRH, modified laparoscopic radical hysterectomy; OS, overall survival; DFS, disease-free survival; PFS, progression-free survival.

Additional file 4. Comparison of survival prognosis by surgical approach (adjuvant therapy). Adjuvant therapy: AB without adjuvant therapy (A: DFS, B: OS), CD with adjuvant therapy (C: DFS, D: OS). ORH, open radical hysterectomy; MLRH, modified laparoscopic radical hysterectomy; OS, overall survival; DFS, disease-free survival; PFS, progression-free survival.

Additional file 1. Comparison of survival prognosis by surgical approach (clinical stage). Clinical stage: IB1 (A: DFS; B: OS); IIA1 (C: DFS; D: OS). ORH, open radical hysterectomy; MLRH, modified laparoscopic radical hysterectomy; OS, overall survival; DFS, disease-free survival; PFS, progression-free survival.

Additional file 3. Comparison of survival prognosis by surgical approach (invasion depth). Invasion depth: Inner 1/3 (A: DFS; B: OS); Middle 1/3 (C: DFS; D: OS); Deep 1/3 (E: DFS; F: OS). ORH, open radical hysterectomy; MLRH, modified laparoscopic radical hysterectomy; OS, overall survival; DFS, disease-free survival; PFS, progression-free survival.

Additional file 3: Figure S1. The cell viability of MSC or MSCATV after 72h treatment measured by MTT assay. ns: no significance.

Additional file 5: Figure S2. Molecule size ranges of RNA samples from MSC-EV and MSCATV-EV. RNA molecule size ranges of four MSC-EV (A) and four MSCATV-EV (B) were established by Agilent 2200 TapeStation Instrument. HSRNA ladders include 25, 200, 500, 1,000, 2,000, 4,000 and 6,000 nt.

Additional file 6: Figure S3. Non-coding RNA annotation of MSC-EV and MSCATV-EV. The mapped read counts were plotted on a log-scale. “Others” refer to the reads that cannot be mapped to the known non-coding RNA reads.

Additional file 8: Figure S5. The original image of Fig. 4G (Interaction network between target genes of three upregulated miRNAs (miR-139-3p, miR-320-3p, miR-501-3p) and downregulated genes in human monocyte-derived M2 macrophages (GEO: GSE32164)).

Additional file 9: Figure S6. Consensus sequence of rno-miR-139. Stacked histogram displays the counts of mapped reads to rno-miR-139 in miRNA-seq of MSC-EV (red) and MSCATV-EV (blue). Seqlogos of mapped reads were displayed above the histogram while reference sequence of rno-mir-139 marked with the locations of rno-miR-139-5p and rno-miR-139-3p were displayed below the histogram.

Additional file 7: Fig. S7. Structure of nirK and nirS communities in the absence or presence of AMF. Pot expt 1. Relative abundance of major taxonomic groups of nirK and nirS communities under the −AMF and +AMF treatments in different patches (n = 8). Control, soil patch; NSfaba and Sfaba, patches with unsterilized (NS) or sterilized (S) faba bean residues, respectively; asterisks, significant differences between the −AMF and +AMF treatments in each patch type according...

Additional file 1: sFigure 1. Accumulation of hyperphosphorylated tau is remarkably increased in the medial septum (MS) of AD mouse models. (A-B) Representative images showing prominent accumulation of phosphorylated tau (pT205 and pT231) in the MS of 9-month 3xTg AD mice (A) and 5xFAD mice (B) measured by immunofluorescence staining. N = 3 mice per group. Scale bar, 50 μm.

Supplemental material, sj-png-1-taj-10.1177_20406223221143245 for Chest X-ray features facilitate screening for pulmonary hypertension caused by fibrosing mediastinitis by Mingfang Zhou, Bo Li, Yaling Chen, Aqian Wang, Yining Zhu, Yu Li, Hongling Su, Jingchun Fan, Yan Zhang and Yunshan Cao in Therapeutic Advances in Chronic Disease

Shared seismic reflection sections used in the paper "New genesis model of megacorrugations in detachment faults documents the evolution of intermediate-type passive continental margins" published on Tecronics.