5 Works

Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif

Robert Brewster
Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network, whose role in altering gene expression remains unclear. Here, we study a common autoregulatory network motif, the negative single-input module, to explore the regulatory properties inherited from the motif. Using stochastic simulations and a synthetic biology approach in E. coli, we find that the TF gene and its...

Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif

Robert Brewster
Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network, whose role in altering gene expression remains unclear. Here, we study a common autoregulatory network motif, the negative single-input module, to explore the regulatory properties inherited from the motif. Using stochastic simulations and a synthetic biology approach in E. coli, we find that the TF gene and its...

Inherent regulatory asymmetry emanating from network architecture in a prevalent autoregulatory motif

Robert Brewster
Predicting gene expression from DNA sequence remains a major goal in the field of gene regulation. A challenge to this goal is the connectivity of the network, whose role in altering gene expression remains unclear. Here, we study a common autoregulatory network motif, the negative single-input module, to explore the regulatory properties inherited from the motif. Using stochastic simulations and a synthetic biology approach in E. coli, we find that the TF gene and its...

Coronavirus Infographic

Angela Messmer-Blust
To help give children a better understanding of the coronavirus that is causing the COVID-19 disease and the disruption in our daily lives, the RNA Therapeutics Institute (RTI) at UMass Medical created this infographic just for kids. We hope parents and teachers can use it to help explain this complex situation, while also teaching the wonders of science.

ABCs of COVID-19 Coloring Page

Angela Messmer-Blust
To help give children a better understanding of the coronavirus that is causing the COVID-19 disease and the disruption in our daily lives, the RNA Therapeutics Institute (RTI) at UMass Medical created this coloring page just for kids. We hope parents and teachers can use it to help explain this complex situation, while also teaching the wonders of science.

Registration Year

  • 2020
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Resource Types

  • Image
    5

Affiliations

  • University of Massachusetts Medical School
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