Additional file 1. Figure S1. ABCB4 genotypes of the 12 unrelated families on Sangersequencing or next generation sequencing. Arrows indicated the mutations. Since Sangervalidation through forward sequencing or reverse sequencing, the base of the peak map maybe the reverse complemen tation sequence of the base detected.

Additional file 2: Fig. S2. Effet of Pro on OBs and PCa cells. (A) Compounds that suppress the viability of C4-2B cells have different effects on RLI. (B) Viability of C4-2B cells treated with Pro at indicated concentrations.

Additional file 2: Fig. S1. Selection of a base medium for HA production.

Additional file 2: Fig. S1. Selection of a base medium for HA production.

Additional file 4: Fig. S3. Phylogenetic analysis based on the amino acid sequences of proteins encoded by ORF22 a and ORF2643 b in P. agglomerans ZJU23.

Additional file 4: Figure S3. Impact of IRAK-M knockdown on cytokines production in A549 cells. Expression of IL-6, IL-8, CXCL10, CXCL11 and IFN-γ at both mRNA level and protein level after (a) IL-1β (1 ng/ml), (b) TNF-α (10 ng/ml), (c) IL-33 (100 ng/ml) and (d) HDM (10 μg/ml) stimulation for 24 h. mRNA expression of IL-6, IL-8, CXCL10, CXCL11 and IFN-γ were normalized to GAPDH. Values are expressed as mean ± SEM (n = 3)....

Additional file 2: Figure S1. IRAK-M expression is inducible by multiple stimuli in A549 cells. IRAK-M protein expression at 0, 6, 12, 24 h after (a) IL-1β (1 ng/ml), (b) TNF-α (10 ng/ml), (c) IL-33 (100 ng/ml) and (d) HDM (10 μg/ml) exposure. IRAK-M protein expression was normalized to GAPDH. Values are expressed as mean ± SEM (n = 3). *P < 0.05.

Additional file 4: Figure S4.Relative expression of CeqSnRK genes in shoots following different NaCltreatments as determined by RT-qPCR. The Y-axis and X-axisindicate relative expression levels and salt concentration of stress treatment,respectively. Mean values and standard deviations (SDs) were obtained fromthree biological and three technical replicates. The error bars indicate standarddeviation. **P < 0.01 and *P < 0.05.

Additional file 3: Figure S3. Change of stroma percentage between primary site and bone metastasis in Luminal type, HER2 positive type and triple negative type breast cancers.

Additional file 9: Figure S9. Differential expression analysis of BRIP1 in various subtypes across different cancers via TISIDB. Cancer types without statistical significance were shown. (a) The expression of BRIP1 in different molecular subtypes and (b) immune subtypes of cancers.

Additional file 16: Figure S16. Correlation analysis between BRIP1 expression and immune infiltration of CD8+ T-cells. Different algorithms were used to explore the potential correlation between the expression levels of BRIP1 and the infiltration levels of CD8+ T-cells across all types of cancer in TCGA.

Additional file 20: Figure S20. Correlation between BRIP1 expression, immune pathways (a), and immune checkpoints (b) across all TCGA tumors.

Additional file 2. Study and analysis flow chart.

Additional file 1: Fig. S1. Purified macrogametocytes of E. necatrix observed by light microscope. Bar represents 20 μm.

Additional file 1: Fig. S1. Purified macrogametocytes of E. necatrix observed by light microscope. Bar represents 20 μm.

Supplementary Material 1

Additional file 7: Figure S7. Representative FACS plots and bar graphs showing CD45R/B220+ B cells in the spleens of B-NDG mice in non-IR + PBS, IR + PBS, IR + GA, IR-OEa8 + PBS, and IR-OEa8 (PM69) + GA groups.

Additional file 1: Supplementary Figure 1. Normalization processing and analysis of six GEO datasets (GSE4797, GSE6023, GSE45885, GSE45887, GSE9210, and GSE145467).

Additional file 1.

Additional file 2: Supplementary figure 2.

Supplemental material, sj-jpg-1-tam-10.1177_17588359231167818 for Circulating tumor cells dynamics during chemotherapy predict survival and response in advanced non-small-cell lung cancer patients by Zhen Wang, Xu-Chao Zhang, Wei-Neng Feng, Li Zhang, Xiao-Qing Liu, Wei-Bang Guo, Yan-Ming Deng, Qing-Feng Zou, Jin-Ji Yang, Qing Zhou, Bin-Chao Wang, Hua-Jun Chen, Hai-Yan Tu, Hong-Hong Yan and Yi-Long Wu in Therapeutic Advances in Medical Oncology

Additional file 1: Figure S1. Phylogenetic tree of the known dipteran insulin receptor.

Additional file 4: Figure S4. The body size of the female and male adults after feeding dsRNA.

Additional file 3: Figure S3. PCR identification of the recombinant bacterial vector L4440-dsInR and L4440-dsEGFP.

Additional file 2: Figure S2. Expression of ILPs and InR in different tissues of female adults.