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TREND: Bureau of Labor Statistics. Employment and Unemployment - Seasonally Adjusted: Unemployment Rate - Seasonally Adjusted, 01/2012 - 03/2019. Data Planet™ Statistical Datasets: A SAGE Publishing Resource Dataset-ID: 002-001-001

Bureau Of Labor Statistics
datasets.shared.infosheet.CitationMgr@134c Dataset: The unemployment rate represents the number unemployed as a percent of the labor force. Seasonally adjusted estimates are provided for total employment, unemployment, and the unemployment rate. Seasonal adjustment removes the effects of events that follow a more or less regular pattern each year, in order to make it easier to observe the cyclical and other nonseasonal movements in a data series. Data are from the LAUS program (Local Area Unemployment Statistics) program,...

High diagnostic yield and novel variants in very late-onset spasticity

Momen Almomen, Kristina Martens, Asfia Quadir, Carly Sabine Pontifex, Alexandra Hanson, Lawrence Korngut & Gerald Pfeffer
Hereditary spastic paraplegias (HSPs) are a diverse group of genetic conditions with variable severity and onset age. From a neurogenetic clinic, we identified 14 patients with very late-onset HSP, with symptoms starting after the age of 35. In this cohort, sequencing of known genetic causes was performed using clinically available HSP sequencing panels. We identified 4 patients with mutations in SPG7 and 3 patients with SPAST mutations, representing 50% of the cohort and indicating a...

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