2 Works

Liberal versus Political Models of Global Governance (LIEPP Working Paper, n°97)

Ian Hurd
Scholarship on international law in political science is dominated by a liberal paradigm that seeks to distinguish legal forms from political ones. The liberal approach offers a consensual model of international law in which legalization is a manifestation of intergovernmental cooperation in the pursuit of mutual goals. These two assumptions - that law is cooperative and that cooperation is a normative good - lead liberal global governance scholars away from key political questions about international...

Booster vaccination is required to elicit and maintain COVID-19 vaccine-induced immunity in SIV-infected macaques

Pingchao Li, Qian Wang, Yizi He, Chenchen Yang, Zhengyuan Zhang, Zijian Liu, Bo Liu, Li Yin, Yilan Cui, Peiyu Hu, Yichu Liu, Pingqian Zheng, Wei Wang, Linbing Qu, Caijun Sun, Suhua Guan, Liqiang Feng & Ling Chen
Prolonged infection and possible evolution of SARS-CoV-2 in patients living with uncontrolled HIV-1 infection highlight the importance of an effective vaccination regimen, yet the immunogenicity of COVID-19 vaccines and predictive immune biomarkers have not been well investigated. Herein, we report that the magnitude and persistence of antibody and cell-mediated immunity (CMI) elicited by an Ad5-vectored COVID-19 vaccine are impaired in SIV-infected macaques with high viral loads (> 105 genome copies per ml plasma, SIVhi) but...

Registration Year

  • 2022
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Affiliations

  • Northwestern University
    2
  • University of Tennessee Health Science Center
    1
  • Yunnan University
    1
  • North West Agriculture and Forestry University
    1
  • Sixth Affiliated Hospital of Sun Yat-sen University
    1
  • Sun Yat-sen University
    1
  • Agricultural Genomics Institute at Shenzhen
    1
  • West China Hospital of Sichuan University
    1
  • Zhejiang University
    1
  • Institute of Hydrobiology
    1