22,685 Works

Effective brain connectivity through a constrained autoregressive model

Alessandro Crimi, Luca Dodero, Vittorio Murino & Diego Sona
Integration of functional and structural brain connectivity is a topic receiving growing attention in the research community. Their fusion can, in fact, shed new light on brain functions. Targeting this issue, the manuscript proposes a constrained autoregressive model allowing to generate an “effective” connectivity matrix that model the structural connectivity integrating the functional activity. In practice, an initial structural connectivity representation is altered according to functional data, by minimizing the reconstruction error of an autoregressive...

Consolidated ITS2 database and search engines for plant biomarker analyses

, Hong Bai, & Kang Ning

Computational workflows for research students

& Melissa J. Davis
The majority of new bioinformatics research students are often not acquainted with the common computational workflows and resources. Students may spend several months writing scripts to perform routine analysis, for which a comprehensive set of tools might have already been developed.

In this talk/poster, the core Bioconductor technologies are introduced. The term Reproducible Research is defined. I, then, introduce Docker and explain how it can be deployed to build a digital archive that reproduces the research...

SuperTranscript: a reference for the visualisation and analysis of transcriptome data.

Anthony Hawkins, Alicia Oshlack & Nadia Davidson
A poster presentation explaining the novel reference of the transcriptome: a SuperTranscript, as well as documentation of the methodology of the Lace software which produces SuperTranscript from RNA-seq data (for non-model and model organisms). Several of the new and exciting applications for SuperTranscripts are described in the poster. The poster was created for the ABA3CUS conference in Brisbane, Australia 2016.

Epidemiological and etiological diagnosis of suppurative keratitis in Vadodara,Gujarat,India

Priyanka Sharma
Background- Corneal blindness is a major public health problem in India and infections constitute a major cause, second only to cataract .The purpose of this study was to identify the specific organisms responsible for suppurative keratitis, and to determine the risk factors predisposing to suppurative keratitis in Vadodara, Gujarat.

Conclusions- Suppurative keratitis is one of the leading causes of blindness in rural India and most often occurs due to superficial corneal trauma, accounting for 84.84% of...

Outbreak of measles in Bhelterghat, Ghanapara and Pekbeki, Goalpara, Assam, India, 2015

, Samir Sodha, , , , Anil Kumar & Srinivas Venkatesh
Background
Among 21.5 million children globally who did not receive a single dose of measles vaccine in 2013, 6.4 million (30%) were in India, resulting in a large susceptible population at risk for propagating measles outbreaks. On March 20, 2015, a single health facility in Goalpara District in Assam reported 73 children < 18 years with fever and rash. We investigated the suspected measles outbreak to confirm and describe the outbreak, estimate vaccine effectiveness, and propose...

Cryptococcus meningitis and the genotypes of Cryptococcus neoformans prevalent in Western Maharashtra, India

Sujata Dharmshale, Renu Bharadwaj & Anju Kagal
Cryptococcosis is second most common opportunistic fungal infection in immuno-compromised patient with increased mortality and morbidity. It is caused mostly by C. neoofrmans var grubii (serotype 'A'). Other species C. gattii predominantly isolated from immunocompetent patient. There are various diagnostic methods available viz: microscopy, culture, antigen detection and molecular tests. In the present study diagnostic techniques used were evaluated using PCR as reference method. It was found that antigen detection method was more sensitive and...

Towards a national action plan for antimicrobial resistance: the Kenyan experience

Eveline Wesangula, Veronica Kamau, , & Rachel Kamau

Viral aetiologies of acute encephalitis in a hospital-based population in Sri Lanka

, , , , Padma Gunaratne, , &

Detection of clusters and geographical hotspots for Lassa fever in Edo Central Senatorial District of Nigeria: a step into a Nation-wide mapping of Lassa fever

& Danny Asogun
Lassa fever is a viral hemorrhagic fever and a neglected tropical disease which was first discovered in Nigeria in 1969. The disease occurs mainly in West Africa with a few imported cases into Europe. The first reported outbreak was in a village called Lassa located in the North Eastern part of Nigeria followed by a nosocomial outbreak in a mission hospital in Jos, Nigeria. This initial report was restricted to only two states in Northern...

Molecular diversity of rotavirus strains from hospitalized children in Central Kerala

, , , , Seema Oommen & Sara Chandy

The human microbiome research in Africa – a systematic review

Michelle Ngwarai, , Heather Zar, Mark Nicol & Mamadou Kaba
Background: The increasing interest in the human microbiome was sparked in part by two initiatives launched in 2008, the European and Chinese-led Metagenomics of the Human Intestinal Tract Consortium and the National Institutes of Health (NIH)-sponsored Human Microbiome Project. The new knowledge provided by these initiatives and others worldwide are transforming our understanding of the pathogenesis of several diseases, including asthma, inflammatory bowel diseases, obesity and Type 1 diabetes, as well as the development of...

Aerobic bacteria in infected breast of Turkish woman: prevalence and antimicrobial resistance evaluated in cases with lactational mastitis, periductal mastitis and granulomatous mastitis

Zeynep Taner, , Mehmet Velidedeoğlu, , Varol Celik, Mehmet Demirci, Fatih Dal, Yasemin Kucuk, Birgül Mete, , Suphi Vehid, Bekir Kocazeybek, Bekir Gunaydın & Nuri Kiraz
Mastitis is a disease causing serious psychological and physical difficulties in women. We report the aerobic bacteria isolated from infected breasts of 44 women diagnosed with lactational mastitis, 10 with periductal mastitits and 40 diagnosed with granulomatous mastitis.

Insilico analysis of Micro RNA based target interaction associated with pharmacogenomics of acquired immune deficiency syndrome

& Daniel Alex Anand
Analysis of Micro RNA based regulatory networks in Infectious diseases is a challenging task in the era of Post genomics and prediction of the miRNAs associated with Pharmacogenomics of Acquired Immune Deficiency Syndrome (AIDS) is an initiation towards the miRNA based therapy for AIDS.

Based on the statistical analysis of gene and miRNA regulated networks, it was found that hsa-miR-18a show a good statistical significance towards genes which are related to AIDS and in future, hsa-miR-18a...

An outbreak of diphtheria in K’Bang district, Gia Lai, Viet Nam, October 2013 – July 2014

Doanh Pham, Duoc Pham, Long Vu, Hien Do, Tuyen Chu, Vinh Nguyen, Hoa Ra Lan, Trang Ly, Thanh Pham, Ha Nguyen, Ha Ninh &
Background: Diphtheria has not been recorded in Gia Lai province since 2004. Beginning in October 2013 a large number of suspected cases were reported from K’Bang District hospital, including two deaths. This study describes the epidemiological characteristics of these cases.

Conclusions: The diphtheria outbreak in K’Bang from 2013 through 2014 disproportionately affected children <15 years old, an ethnic minority group, and children of the poor, and illiterate. Rates of immunization in this community have been...

Leishmania disease gap analysis study – Pakistan

Syed Mursalin &
Pakistan is rated among one of the high Leishmania prevalent countries. The rising incidence of Leishmania in Pakistan are marked by poverty, poor healthcare, inadequate vector control, refugees, inadequate healthcare system and drug shortages. Disease is being reported from all over the country specially the remote underserved mountainous areas of Sindh, Khyber and Baluchistan provinces.

To address this Pakistan OneHealth Alliance (POHA) in partnership with Ministry of Health Services (MOHS), and international partners (CORDS, SECID,...

Antibiotic resistance pattern of HA-MRSA strains isolated from leukemia patients in Baghdad, Iraq

Noor Al-Azawi, Khalid Mohammed Ali, Alaa Alwan, Sinan Al-Rifai &
This study aimed to evaluate MRSA strains isolated from leukemia patients admitted to hospitals in regard to drug resistance.

Molecular characterization of Mycobacterium tuberculosis Strains isolated in India

, Mani Sankar, Parveen Kumar, David Couvin, &
Background: Genotypic analyses of Mycobacterium tuberculosis are essential in understanding its epidemiology and transmission in a region. Spoligotyping and 24 Loci MIRU-VNTR are widely used PCR based rapid methods for genotyping M. tuberculosis complex (MTB) strains. Only few in-depth analyses of the population structure of MTB are known from India. In this study we executed genotyping of M. tuberculosis complex clinical isolates from different geographical regions of India.
Materials and Methods: A total of 628 M....

Antibiotic sensitivity Patterns among ESBL UTIs in Sri Lanka

, , , , , , & Ranjan Premaratna

Sri Lanka: nationwide epidemiology of melioidosis

, Jayanthi Masakorala, , , , & Tim Inglis
This study is first nationwide study on the epidemiology of melioidosis in South Asia. It documents the demographic and geographic distribution of melioidosis including probable exposures, underlying comorbidities, clinical presentation and outcome. South Asia has probably the largest burden of disease in melioidosis but it is largely unknown. This study uses passive laboratory based and active ward based surveillance to elucidate the distribution of melioidosis in Sri Lanka. It has revealed that melioidosis is not...

Evaluation of acute Encephalitis syndrome/Japanese Encephalitis surveillance system, Barpeta and Sivasagar Districts, Assam, India 2012-2013

&
Background: Japanese Encephalitis (JE) virus leads to acute encephalitis syndrome (AES) and is the leading cause of vaccine-preventable encephalitis in Asia. We evaluated the AES/JE surveillance system in Assam, India to identify strengths and constraints.

Conclusion: Our surveillance evaluation found the JE surveillance system was timely but not representative, as all private health facilities were not reporting. This system has high sensitivity. We recommend increasing awareness of AES/JE and improved coordination with public and private health...

Atypical enteropathogenic E. coli as a cause of pediatric diarrhea

Deepika Manjunathan, , Jharna Mandal, , & Rahul Dhodapkar
Diarrhogenic Escherichia coli (DEC) is the second most important cause for mortality and morbidity among children. Among the DEC, enteropathogenic E.coli(EPEC) has become the major cause for diarrhea in children less than five years of age. Serotyping helps in determining the pathotype but is cumbersome, expensive and has lot of cross reactions. In this regard, Polymerase chain reaction (PCR) is a reliable and rapid tool for its identification than serotyping.

Aim: This study was conducted to...

Registration Year

  • 2016
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Affiliations

  • University of California, Berkeley
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