1,668 Works

The hydromedusae of the west coast of North America with special reference ot those of the Vancouver Island region

R. Earle Foerster
[Abstract not available]
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Protein tyrosine phosphatase PRL-3 expression and transcriptional regulation in cancer and metastasis

Patrick Chun Wei Wong
Elevated expression of protein tyrosine phosphatase PRL-3 is implicated in cell migration, invasion, and metastasis, although the molecular targets of this phosphatase remain unidentified. PRL-3 expression is strikingly upregulated in metastatic colon carcinoma, compared with much lower expression in primary colon tumours and virtually undetectable expression in normal colon epithelia. Increased transcriptional activity is suggested to account for increased PRL-3 expression in 75% of the metastatic samples. We used bioinformatics analyses and cell-based promoter assays...
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The systematics, zoogeography and evolution of Dolly Varden and bull trout in British Columbia

Gordon Robert Haas
An analysis of the systematics, zoogeography and evolution of the Dolly Varden char species complex in British Columbia is presented. These features of this species complex and the morphometric statistical procedures used in these analyses have both long been the subjects of strong debate and also have recently seen much renewed interest and work. This thesis assesses both these areas and is divided into those two parts. The first section deals with these three biological...
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Studies on the structure of human haptoglobin chain

Choy-Leong Hew
Haptoglobins are a group of glycoproteins found in normal human serum and are capable of binding hemoglobin both in vivo and in vitro. Haptoglobin 2-1, one of the common haptoglobin phenotypes was isolated in large quantity from the ascites fluid. Upon reduction and alkylation in the presence of 8 M urea, haptoglobin dissociates into two different classes of polypeptide chains, the α and the β chains. The haptoglobin β chain, which is the larger and...
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Separation of immunoglobulins from egg yolk using metal chelate interaction chromatography and ion exchange chromatography

Anne Marie McCannel
The immune response of chickens immunized with β-N-acetylglucosaminidase was monitored in the egg yolks of the birds using an enzyme-linked immunosorbent assay. Significantly higher levels of specific antibodies were detected in the yolks of the birds immunized with the enzyme when compared with the yolks of a control bird collected over the same period significant differences also were found in the response within the immunized group of birds, indicating individual variability to the injections. Immunoglobulins...
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The Geology and ore deposits of the Howards Pass Area, Yukon and Northwest Territories : the origin of basinal sedimentary stratiform sulphides deposits

John Michael Morganti
Economically important sedimentary-type stratiform Zn-Pb deposits exist in the Lower Silurian basinal facies of the Selwyn Basin along the Yukon-Northwest Territories border. Three major similar deposits have been defined to date, and are referred to collectively as the Howards Pass deposits. The Pre-Mesozoic history of the Howards Pass area was dominated by three major basin systems. During the Late Hadrynian to Early Cambrian the 'Grit Unit' was deposited as a clastic wedge with a western...
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Primary photochemical processes in hexafluorobiacetyl

William John Reid
Absolute photochemical quantum yields of hexafluoro-biacetyl vapour have been obtained at various exciting wavelengths between 250 and 440 nm over the range 0.5 - 400 torr. The yields are strongly dependent on pressure demonstrating that vibrational relaxation is the dominant process competing with unimolecular dissociation. It is found that two different states contribute to dissociation. One is identified as the excited singlet level reached on excitation. The other is attributed to the vibronic level reached...
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Geology of the guano-guayes rare earth element bearing Skarn property, Pelly Mountains, Yukon Territory

Felicie Jane Chronic
The Guano-Guayes property, in the Pelly Mountains of the Yukon Territory, covers a rare earth element (REE) bearing contact metamorphic aureole which developed around a syenite stock during Mississippian time (319 ± 10 Ma phlogopite K-Ar date, 333 ± 10 Ma Rb-Sr skarn mineral isochron). Sedimentary rocks consist of several hundred metres of Ordovician dark gray shale which are faulted upward adjacent to 450 m of Silurian interbedded impure calcite and dolomite marbles and quartzites...
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Electron spin resonance of some vanadyl, copper and cobalt porphyrins

Pui-Wah Lau
Electron Spin Resonance study was carried out on a series of metalloporphyrins (where metal = VO²⁺, ⁶³Cu²⁺ , and CO²⁺, porphyrin = (4-pyridyl)porphin, (p-carboxylphenyl)porphin, tetrabenzporphyrin, and octamethyltetrabenzporphyrin), magnetically diluted in the free base porphyrins, or organic solvents, aiming at the understanding of the electronic structures of these biological important compounds and the factors affected them. In the case of vanadyl porphyrin, the unpaired electron was found to be in the b₂ orbital. The changes in...
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Chld’s play : a children’s theatre at Vanier Park

Brian Laing Billingsley
The design of a children's theatre at Vanier Park in Vancouver, British Columbia, is loosely based upon the model and philosophical underpinnings of the Vancouver Children's Festival. The theatre is situated in the present site of the Children's Festival, designed to provide children with year round access to the arts. A liaison between school children or a venue for professional travelling troupes, the theatre is designed to accommodate any size of performance. The integration of...
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Images and structure in Nathanael West's novel satires

Gordon Burnett Alexander
Before we can judge a writer, we must tentatively decide upon the appropriate criteria by which to measure his achievement. Various critics have praised Nathanael West for the exact things for which others have damned him. This study is an attempt to clarify the nature of West's work, and thereby to clarify the grounds upon which he must be judged. The nature of his fictional world is crucial. This study puts West's images, which are...
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The leftovers of planet formation : small body populations of our solar system and exoplanet systems

Samantha Lawler
The small body populations within a planetary system give information about the planet formation and migration history of the system. In our Solar System, we study these bodies (asteroids, comets, and trans-Neptunian objects), by directly observing them in reflected light. In other solar systems, dust traces the position of the planetesimal belts that produce it, and is observed as an excess above the stellar flux in the infrared. The dust is visible and not the...
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The development of a garrison mentality among the English in Lower Canada, 1793-1811

Frank Murray Greenwood
The mutual antagonism of French and English speaking Canadians, during the first decade of the nineteenth century has been explained by historians in a variety of ways. Traditional French Canadian historiography attributes much of the trouble to the machinations and religious and racial bigotry of a handful of bureaucrats. The neo-nationalist school of the University of Montreal maintains that the conflict was the inevitable result of the "decapitation" of French Canadian society at the Conquest...
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Building on a living heritage : adaptive reuse of a railyard roundhouse

Barbara Lynn Gordon-Findlay
The reuse of existing buildings designed for a specific purpose that has become obsolete is an activity increasingly relevant in today's society. At one end of the spectrum is the complete obliteration of historical artifacts to make way for new development. At the other end is the preservation of an instant in time held eternally distant as a museum. The body of effort expended in the 1970's resulted in much commendable legislation to protect our...
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Reducing the surface checking of deck-boards exposed to natural weathering: effects of wood species and surface profiling

Kenneth Jenkye Cheng
Surface checking is a defect in wood decking that is highly disliked by consumers. Surface checking can be reduced by selecting species that are more resistant to checking, or profiling deck-boards with a series of V(rib) or U(ripple) shaped grooves. Most literature on checking of decking focuses on species that are already used as exterior products. This provides an opportunity to investigate the use of other under-utilized species as deck-boards. Surface profiling has been applied...
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Roles of mother in Humperdinck's Hansel and Gretel and Popova in Walton's The Bear

Karyn Audra Way-McClarty
None provided.
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Stress in the hospital setting and the use of critical incident stress debriefing

Marilyn May Gough
Unaddressed worker stress among hospital based professionals represents a serious threat to quality health care. Such costly outcomes as increased absenteeism, job turnover and substandard or failed client interventions are only a few of the possible serious consequences. In spite of this threat, minimal attention has been given to developing and implementing comprehensive stress management programs in this setting. Stress management strategies that do exist tend to be short term and focused on high profile...
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Effect of grass maturity and wilting on the nitrogen fractions in silage, their rate and extent of degradation in the rumen

Nathaniel Fungayi Makoni
The available literature indicates that, silages containing more undegraded protein will be better feeds for high levels of production from ruminants. Ensiling excessively wet herbage will increase degradation of both protein and energy. Ensiling wilted herbage will increase aerobic losses initially, during compaction and later, during removal which decreases digestibility. This study was carried out, to evaluate the effect of grass/legume maturity and wilting on the nitrogen fractions in silage, their rate and extent of...
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Synthesis of P,N-chelate phosphaalkene–oxazoline ligands and their applications in asymmetric catalysis

Julien Dugal-Tessier
This thesis outlines the design, synthesis and utilization of phosphaalkene-based ligands for asymmetric catalysis. Transition metal catalysis studies that utilize achiral phosphaalkene-based ligands are reviewed in Chapter 1. In addition, the synthesis and reactivity of phosphaalkenes are briefly introduced in this chapter. The reactivity of a palladium(II) phosphaalkene complex [MesP=CPh(2-py)⋅PdCl₂] bearing the smaller P-Mes substituent compared to the traditional Mes* is described in Chapter 2. This complex was found to be a competent catalyst for...
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Structure-function relationships in a f3-1,4-glycanase (Cex) from Cellulomonas fimi: identification of catalytic residues

Alasdair Muir MacLeod
The objective of this study was to identify and examine the roles of catalytic residues in the active site of a ß-1,4-glycanase (Cex) from the bacterium Cellulomonas fimi. The use of the Gram positive bacterium, Streptomyces lividans, as a host for the expression of the cex gene was explored. The cex gene was successfully expressed in S. lividans from the aph promoter of p1J680-cex. The polypeptide was efficiently exported to the culture medium. Yields of...
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The B.C. mushroom industry : an analysis of demand and supply

Hsin Chung Huang
The mushroom industry in British Columbia markets and distributes through a central selling agency under the trademark Money's Mushrooms. This member owned agency also exercises control, through production area quotas, on member production. This study analyses the market behavior of the B.C. mushroom industry¹, in order to ascertain whether producers collectively exercise monopoly control over the industry. The main structural components of the industry are described in a mathematical model using a partial equilibrium analysis....
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The syntheses and reactions of carbonyl(phosphine)(thiolator)ruthenium(II) complexes

Philip Gregory Jessop
The chemistry of homogeneous transition metal systems offer parallels to the reactions on the surfaces of industrial hydrodesulphurization catalysts. The reactions of several ruthenium complexes with sulphur-containing reagents are described, with an emphasis on the kinetics and mechanisms thereof. The complex Ru(CO)₂(PPh₃)₃ (2), for example, reacts quickly with thiols and disulphides, producing cct-RuH(SR)(CO)₂(PPh₃)₂ (9) and cct-Ru(SR)₂(CO)₂(PPh₃)₂ (14), respectively, although 2 fails to react with unstrained thioethers. Reactions of the related complex Ru(CO)₂(PPh₃)(dpm) (dpm=Ph₂PCH₂PPh₂) are complicated...
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Influence of brood-size on reproductive success of two species of cormorant, Phalacrocorax auritus & P. pelagicus, and its relation to the problem of clutch-size.

Ian Robertson
Brood-rearing capabilities and their relation to the problem of clutch-size were investigated in two cormorant species, Phalacrocorax auritus and P. pelagicus, at Mandarte Island, British Columbia. Extra chicks were added to normal sized broods (1 to 4 chicks) so that the range of brood-sizes studied was 1 to 8 in Double-crests (auritus) and 1 to 7 in Pelagics (pelagicus). Fledging success in Double-crests is generally 90 per cent or higher in broods of up to...
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New [3+3] Schiff-base macrocycles and their complexes

Amanda Jane Gallant
A series of conjugated [3+3] Schiff-base macrocycles containing both a central crown ether-like pocket and three tetradentate N[sub 2]O[sub 2] binding sites were prepared and investigated. The formation mechanism was investigated through the synthesis and study of macrocycle fragments. Further understanding of the macrocycle conformations and dynamics was obtained through computational studies. A monoreduced macrocycle where one of the six imines has been reduced was obtained as a by-product of macrocycle formation. Reactivity studies and...
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The molecular pathology of lecithin : cholesterol acyltransferase deficiencuy

John Stuart Hill
Epidemiological studies have indicated that decreased levels of plasma HDL are associated with an increased risk of coronary artery disease. However, there are several rare familial disorders of HDL metabolism in which, despite very low levels of HDL cholesterol, affected individuals do not appear to be at an increased risk for premature atherosclerosis. Examples of such disorders include familial LCAT deficiency and fish eye disease which are rare autosomal recessive diseases associated with inherited defects...
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Registration Year

  • 2015
    1,668

Resource Types

  • PhysicalObject
    1,668