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Boer Goat Production Performance, Constraints And Opportunites In Nepal

Sudha Sapkota, Manisha Kolakshyapati, Samaya Gairhe, Namdev Upadhyaya & Yogendra Acharya
Khari goat is an indigenous breed of goat (Capra hircus) in Nepal. Innovative farmers are eager to change the livelihood through raising new and improved breed of goat. This study was conducted to find out the Boer goat production performance, constraints and opportunities in Nepal. Primary data were collected from purposive sample of 43 respondents from Dhading district and 36 Boer and 36 Khari goats from Goat Research Station, Bandipur. The data were analyzed through...

Boer Goat Production Performance, Constraints And Opportunites In Nepal

Sudha Sapkota, Manisha Kolakshyapati, Samaya Gairhe, Namdev Upadhyaya & Yogendra Acharya
Khari goat is an indigenous breed of goat (Capra hircus) in Nepal. Innovative farmers are eager to change the livelihood through raising new and improved breed of goat. This study was conducted to find out the Boer goat production performance, constraints and opportunities in Nepal. Primary data were collected from purposive sample of 43 respondents from Dhading district and 36 Boer and 36 Khari goats from Goat Research Station, Bandipur. The data were analyzed through...

RAPID ASSESSMENT OF AVAILABILITY OF TOBACCO DEPENDENCE PHARMACOTHERAPY IN PHARMACIES IN SELECTED STATES OF INDIA-A TELEPHONIC SURVEY

Gunjan Kumar, Palanivel Chinnakali, Arvind Kumar, Jency Antony, Sitanshu Sekhar Kar, Senior Resident, Junior Resident & Mph Trainee

From Silos to Synergy: Learning from Politically Informed, Gender Aware Programmes

Chris Roche, Helen Derbyshire, Sam Gibson & David Hudson

Nucleoside diphosphate kinase 2 confers acquired 5-fluorouracil resistance in colorectal cancer cells

Shaojia Wen, Xun Wang, Yamin Wang, Jianfeng Shen, Junyi Pu, Hui Liang, Chao Chen, Linna Liu & Penggao Dai
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. 5-fluorouracil (5-FU)-based chemotherapeutic regimens are routinely used for the treatment of patients with CRC. However, recurrence and chemotherapeutic drug resistance limit the survival rates of patients with CRC. DNA methylation participates in diverse cellular processes by regulating the transcription of a large number of genes expression, cell division, apoptosis, cell adhesion and differentiation, and metabolism, thus it might mediate chemoresistance. Using an Illumina...

Nucleoside diphosphate kinase 2 confers acquired 5-fluorouracil resistance in colorectal cancer cells

Shaojia Wen, Xun Wang, Yamin Wang, Jianfeng Shen, Junyi Pu, Hui Liang, Chao Chen, Linna Liu & Penggao Dai
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. 5-fluorouracil (5-FU)-based chemotherapeutic regimens are routinely used for the treatment of patients with CRC. However, recurrence and chemotherapeutic drug resistance limit the survival rates of patients with CRC. DNA methylation participates in diverse cellular processes by regulating the transcription of a large number of genes expression, cell division, apoptosis, cell adhesion and differentiation, and metabolism, thus it might mediate chemoresistance. Using an Illumina...

Adoption Of Artificial Insemination Technology In Dairy Animals And Impact On Milk Production - A Case Study In Nawalparasi And Chitwan Districts Of Nepal

Sudha Sapkota, Samaya Gairhe, Manisha Kolakshyapati & Namdev Upadhyaya
Artificial insemination in dairy animals is a popular technology to show the performance of new breed in developed countries. Practice of AI is gaining popularity in Nepal also. Household survey, checklist, Focus Group Discussion (FGD) and Key Informant Information (KII) were used to collect the primary data. Secondary data were also collected by literature review. Statistical tools; mean and percentage were calculated and a probit model was run to analyze the data. Result of the...

Adoption Of Artificial Insemination Technology In Dairy Animals And Impact On Milk Production - A Case Study In Nawalparasi And Chitwan Districts Of Nepal

Sudha Sapkota, Samaya Gairhe, Manisha Kolakshyapati & Namdev Upadhyaya
Artificial insemination in dairy animals is a popular technology to show the performance of new breed in developed countries. Practice of AI is gaining popularity in Nepal also. Household survey, checklist, Focus Group Discussion (FGD) and Key Informant Information (KII) were used to collect the primary data. Secondary data were also collected by literature review. Statistical tools; mean and percentage were calculated and a probit model was run to analyze the data. Result of the...

Remediation in Canadian medical residency programs: Established and emerging best practices

Cindy Shearer, Mark Bosma, Fiona Bergin, Joan Sargeant & Andrew Warren
Background: Policies to guide remediation in postgraduate medical education exist in all Canadian medical schools. This study examines concordance between these policies and processes, and published “best practices” in remediation. Method: We conducted a literature review to identify best practices in the area of remediation. We then reviewed remediation policies from all 13 English medical schools in Canada other than our own and conducted interviews with key informants from each institution. Each policy and interview...

Remediation in Canadian medical residency programs: Established and emerging best practices

Cindy Shearer, Mark Bosma, Fiona Bergin, Joan Sargeant & Andrew Warren
Background: Policies to guide remediation in postgraduate medical education exist in all Canadian medical schools. This study examines concordance between these policies and processes, and published “best practices” in remediation. Method: We conducted a literature review to identify best practices in the area of remediation. We then reviewed remediation policies from all 13 English medical schools in Canada other than our own and conducted interviews with key informants from each institution. Each policy and interview...

Cu(II) complexes of cytosine and 1-methylcytosine with bromide: old motifs and new structures*

Rosaria Bruno, Nadia Marino, Rosanna Adduci, Donatella Armentano & Giovanni De Munno
The preparation from aqueous solutions and crystal structures of the compounds trans-[Cu(1-Mecyt)2Br2] (1), trans-[Cu(cyt)2Br2] (2), [Cu(cyt)4]Br2·2H2O (3), and [Cu(cyt)Br3][Hcyt] (4) (where 1-Mecyt = 1-Methylcytosine and cyt = cytosine) is reported. Compounds 1 and 2 are made of trans-CuL2Br2 molecules [L = 1-Mecyt (1) or cyt (2)]. In 1, the coordination geometry around the central Cu(II) is distorted square pyramidal, while in 2 no such distortion is observed. Two solid-state polymorphs of 1 have been isolated, 1a and 1b, both of which...

Cu(II) complexes of cytosine and 1-methylcytosine with bromide: old motifs and new structures*

Rosaria Bruno, Nadia Marino, Rosanna Adduci, Donatella Armentano & Giovanni De Munno
The preparation from aqueous solutions and crystal structures of the compounds trans-[Cu(1-Mecyt)2Br2] (1), trans-[Cu(cyt)2Br2] (2), [Cu(cyt)4]Br2·2H2O (3), and [Cu(cyt)Br3][Hcyt] (4) (where 1-Mecyt = 1-Methylcytosine and cyt = cytosine) is reported. Compounds 1 and 2 are made of trans-CuL2Br2 molecules [L = 1-Mecyt (1) or cyt (2)]. In 1, the coordination geometry around the central Cu(II) is distorted square pyramidal, while in 2 no such distortion is observed. Two solid-state polymorphs of 1 have been isolated, 1a and 1b, both of which...

Molecular diversity of tuliposide B-converting enzyme in tulip (Tulipa gesneriana): identification of the third isozyme with a distinct expression profile

Taiji Nomura, Ryo Kuchida, Naoki Kitaoka & Yasuo Kato
6-Tuliposide B (PosB), a major secondary metabolite that accumulates in tulip (Tulipa gesneriana), is converted to the antibacterial lactone, tulipalin B (PaB), by PosB-converting enzyme (TCEB). TgTCEB1 and TgTCEB-R, which encode TCEB, are specifically expressed in tulip pollen and roots, respectively, but are hardly expressed in other tissues (e.g. leaves) despite the presence of substantial PosB-converting activity, suggesting the existence of another TCEB isozyme. Here, we describe the identification of TgTCEB-L (“L” for leaf), a...

Molecular diversity of tuliposide B-converting enzyme in tulip (Tulipa gesneriana): identification of the third isozyme with a distinct expression profile

Taiji Nomura, Ryo Kuchida, Naoki Kitaoka & Yasuo Kato
6-Tuliposide B (PosB), a major secondary metabolite that accumulates in tulip (Tulipa gesneriana), is converted to the antibacterial lactone, tulipalin B (PaB), by PosB-converting enzyme (TCEB). TgTCEB1 and TgTCEB-R, which encode TCEB, are specifically expressed in tulip pollen and roots, respectively, but are hardly expressed in other tissues (e.g. leaves) despite the presence of substantial PosB-converting activity, suggesting the existence of another TCEB isozyme. Here, we describe the identification of TgTCEB-L (“L” for leaf), a...

Xylanase and feruloyl esterase from actinomycetes cultures could enhance sugarcane bagasse hydrolysis in the production of fermentable sugars

Nanik Rahmani, Prihardi Kahar, Puspita Lisdiyanti, Euis Hermiati, Jaemin Lee, Yopi, Bambang Prasetya, Chiaki Ogino & Akihiko Kondo
The addition of enzymes that are capable of degrading hemicellulose has a potential to reduce the need for commercial enzymes during biomass hydrolysis in the production of fermentable sugars. In this study, a high xylanase producing actinomycete strain (Kitasatospora sp. ID06-480) and the first ethyl ferulate producing actinomycete strain (Nonomuraea sp. ID06-094) were selected from 797 rare actinomycetes, respectively, which were isolated in Indonesia. The addition (30%, v/v) of a crude enzyme supernatant from the...

Xylanase and feruloyl esterase from actinomycetes cultures could enhance sugarcane bagasse hydrolysis in the production of fermentable sugars

Nanik Rahmani, Prihardi Kahar, Puspita Lisdiyanti, Euis Hermiati, Jaemin Lee, Yopi, Bambang Prasetya, Chiaki Ogino & Akihiko Kondo
The addition of enzymes that are capable of degrading hemicellulose has a potential to reduce the need for commercial enzymes during biomass hydrolysis in the production of fermentable sugars. In this study, a high xylanase producing actinomycete strain (Kitasatospora sp. ID06-480) and the first ethyl ferulate producing actinomycete strain (Nonomuraea sp. ID06-094) were selected from 797 rare actinomycetes, respectively, which were isolated in Indonesia. The addition (30%, v/v) of a crude enzyme supernatant from the...

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