730 Works

Hygiene in der Arztpraxis - Infektionsprävention in der ambulanten Versorgung

Tobias Kramer, Andreas Suck, Hedwig François-Kettner, Petra Gastmeier, Bernd Gruber, Katja Heinze, Elena Kortemeyer, Moritz Liewer, Pamela Reißner, Katharina Rubin, Cornelia Schmitz, Anke Westerberg, Cornelia Winten & Conny Wiebe-Franzen
Die Handlungsempfehlung wendet sich an Sie als Ärzte, Betreiber und Medizinische Fachangestellte (MFA) in ambulanten Praxen und Medizinischen Versorgungszentren (MVZ) sowie an zugehörige Ausbildungsbereiche. Durch ausgewählte praxisnahe Beispiele gibt Ihnen die Handlungsempfehlung die Möglichkeit, Infektionsrisiken im täglichen Umgang mit ihren Patienten zu identifizieren. Die Empfehlungen beleuchten eine Auswahl relevanter Aspekte zur Sicherung ihrer Patienten und Mitarbeitenden. Sie bilden den Stand des aktuellen Wissens ab und stellen in ihrer Umsetzung eine Mindestanforderung dar. Daher fokussiert die...

Current Advances, Challenges, and Opportunities in Stroke Research, Management, and Care

Julius Emmrich, Samuel Knauss & Matthias Endres
Stroke is the second leading cause of death (after heart disease) and a major cause of disability worldwide. Also called a brain attack, typical symptoms of stroke include sudden one-sided weakness and numbness in the face and arm as well as altered speech. Most strokes are ischaemic strokes where arterial blood flow to the brain is interrupted by an embolism or thrombosis. Strokes are less frequently caused by haemorrhage. Non-contrast cranial computed tomography (CT) imaging,...

Tumor heterogeneity in autophagy-dependent ferroptosis

Jingbo Li, Jiao Liu, Yinghua Xu, Runliu Wu, Xin Chen, Xinxin Song, Herbert Zeh, Rui Kang, Daniel J. Klionsky, Xiaoyan Wang & Daolin Tang
Macroautophagy (hereafter referred to as “autophagy”) is a lysosome-mediated degradation process that plays a complex role in cellular stress, either promoting survival or triggering death. Early studies suggest that ferroptosis, an iron-dependent form of regulated cell death, is not related to autophagy. Conversely, recent evidence indicates that the molecular machinery of autophagy facilitates ferroptosis through the selective degradation of anti-ferroptosis regulators. However, the mechanism of autophagy-dependent ferroptosis remains incompletely understood. Here, we examine the early...

Does cumulative exposure to traumatic stressors predict treatment outcome of community-implemented exposure-based therapy for PTSD?

Anna Schneider, Anett Pfeiffer, Daniela Conrad, Thomas Elbert, Iris-Tatjana Kolassa & Sarah Wilker
Background: Posttraumatic Stress Disorder (PTSD) is associated with high levels of functional impairments such as difficulties in academic or occupational performance and in social relationships. With an increasing number of traumatic event types experienced (trauma load), PTSD risk increases in a dose-dependent manner. Accordingly, high rates of PTSD can impair the reconstruction process in post-conflict societies. In order to meet these high needs for mental health services in societies with little access to professional care,...

Does cumulative exposure to traumatic stressors predict treatment outcome of community-implemented exposure-based therapy for PTSD?

Anna Schneider, Anett Pfeiffer, Daniela Conrad, Thomas Elbert, Iris-Tatjana Kolassa & Sarah Wilker
Background: Posttraumatic Stress Disorder (PTSD) is associated with high levels of functional impairments such as difficulties in academic or occupational performance and in social relationships. With an increasing number of traumatic event types experienced (trauma load), PTSD risk increases in a dose-dependent manner. Accordingly, high rates of PTSD can impair the reconstruction process in post-conflict societies. In order to meet these high needs for mental health services in societies with little access to professional care,...

Accumulation and translocation of selenium in a soil–rice system in Guangxi, China

Zhen Wang, Fei Pang & Wei Huang
Selenium (Se) is an essential element for the human body. Humans meet their basic Se requirements primarily through food consumption. The largest Se-rich contiguous area in China is located in the southeast of Guangxi. In this study, the Se accumulation and translocation in the Guangxi rice–soil system was assessed. Organically bound Se (O-Se) was found to be the main type of soil Se (72.5%), and had a good linear relationship with soil total Se (TSe)...

N-terminal prohormone B-type natriuretic peptide variability acts as a predictor of poor prognosis in patients with cardiorenal syndrome type 2

Mingming Ma, Qiao Luo, Xiangnan Dong, Shuang Cui, Berthold Hocher, Shufei Zeng, Wenxue Liang, Qiang Li, Xiaoyi Chen, Xin Chen, Yu Meng, Yongping Lu, Deguang Yang & Lianghong Yin
This study aims to explore the effect of N-terminal pro-brain natriuretic peptide (NT-proBNP) variability (mean absolute difference of the log2 NT-proBNP level measured in hospital) on the prognosis of patients with cardiorenal syndrome (CRS) type 2. Patients with CRS type 2 were retrospectively included. The varied NT-proBNP indications were analyzed. They were NT-proBNP I(pre-treatment), NT-proBNP II(post-treatment), NT-proBNP II/I, ΔNT-proBNP, log2 (NT-proBNP) variability and mean log2 (NT-proBNP). A logistic regression model and survival curves (Kaplan–Meier analysis)...

sj-docx-1-dhj-10.1177_20552076221143903 - Supplemental material for The medical profession transformed by artificial intelligence: Qualitative study

Lina Mosch, Daniel Fürstenau, Jenny Brandt, Jasper Wagnitz, Sophie AI Klopfenstein, Akira-Sebastian Poncette & Felix Balzer
Supplemental material, sj-docx-1-dhj-10.1177_20552076221143903 for The medical profession transformed by artificial intelligence: Qualitative study by Lina Mosch, Daniel Fürstenau, Jenny Brandt, Jasper Wagnitz, Sophie AI Klopfenstein, Akira-Sebastian Poncette and Felix Balzer in Digital Health

Title_authorname_figures_table_ESM.docx from Feasibility of urban bird occurrence and nest amount evaluation by the street-view image virtual survey

Panli Tian, Lei Wang, Qi Li, Chentao Liang, Danqi She, Siyu Liu, Yuwen Chen, Liuyang Yao, Weiqi Wang, Huimei Wang & Wenjie Wang
Bird observation mainly relies on field surveys, which are time-consuming and laborious. In this study, we explored using street-view images in the virtual survey of urban birds and nests. Using the coastal city of Qingdao as the study area, 47 201 seamless spherical photos at 2741 sites were collected using the Baidu street-view (BSV) map. Single-rater-all photo checks and seven-rater-metapopulation checks were used to find inter–rater repeatability, the best viewing layer for BSV collection, and...

Additional file 1 of Reducing urinary catheter use in geriatric patients - results of a single-center champion-led intervention

L Mrziglod, S Saydan, F Schwab, D Zohlnhöfer-Momm, P Gastmeier & S Hansen
Supplementary Material 1

Additional file 1 of The effect of denosumab on disseminated tumor cells (DTCs) of breast cancer patients with neoadjuvant treatment: a GeparX translational substudy

Pauline Wimberger, Jens-Uwe Blohmer, Petra Krabisch, Theresa Link, Marianne Just, Bruno Valentin Sinn, Eike Simon, Christine Solbach, Tanja Fehm, Carsten Denkert, Cristin Kühn, Kerstin Rhiem, Hans Tesch, Sherko Kümmel, Andrea Petzold, Oliver Stötzer, Cornelia Meisel, Jan Dominik Kuhlmann, Valentina Nekljudova & Sibylle Loibl
Additional file 1: Table S1. Baseline Characteristics of the DTC substudy.

Additional file 1 of The impact of the COVID-19 pandemic on processes, resource use and cost in palliative care

Farina Hodiamont, Caroline Schatz, Eva Schildmann, Zulfiya Syunyaeva, Katerina Hriskova, Constanze Rémi, Reiner Leidl, Susanne Tänzler & Claudia Bausewein
Additional file 1: Appendix 1. Boxplots on documented mean minutes spent on patientcare in 2019 and 2020.

Additional file 1 of Genetic liability to age at first sex and birth in relation to cardiovascular diseases: a Mendelian randomization study

Miao Chen, Zhen Wang, Hongfei Xu, Xiaofang Chen, Peng Teng & Liang Ma
Additional file 1. Supplementary Tables of Genetic liability to age at first sex and birth in relation to cardiovascular diseases: A Mendelian Randomization study.

Additional file 2 of Genome-wide characterization of the Triplophysa dalaica slc4 gene family and expression profiles in response to salinity changes

Chuanjiang Zhou, Bo Hu, Yongtao Tang, Xin Chen, Zhigang Ma, Qiqi Ding & Guoxing Nie
Additional file 2: Table S1. Primers used for qRT-PCR of slc4 gene family.

Additional file 3 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

Emily Haeuser, Audrey L. Serfes, Michael A. Cork, Mingyou Yang, Hedayat Abbastabar, E. S. Abhilash, Maryam Adabi, Oladimeji M. Adebayo, Victor Adekanmbi, Daniel Adedayo Adeyinka, Saira Afzal, Bright Opoku Ahinkorah, Keivan Ahmadi, Muktar Beshir Ahmed, Yonas Akalu, Rufus Olusola Akinyemi, Chisom Joyqueenet Akunna, Fares Alahdab, Fahad Mashhour Alanezi, Turki M. Alanzi, Kefyalew Addis Alene, Robert Kaba Alhassan, Vahid Alipour, Amir Almasi-Hashiani, Nelson Alvis-Guzman … & Laura Dwyer-Lindgren
Additional file 3: Supplemental figures.Figure S1. Prevalence of male circumcision. Figure S2. Prevalence of signs and symptoms of sexually transmitted infections. Figure S3. Prevalence of marriage or living as married. Figure S4. Prevalence of partner living elsewhere among females. Figure S5. Prevalence of condom use during most recent sexual encounter. Figure S6. Prevalence of sexual activity among young females. Figure S7. Prevalence of multiple partners among males in the past year. Figure S8. Prevalence of...

Additional file 7 of The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model

Yunfei Li, Junjie Xu, Xuefei Guo, Zhiwei Li, Lili Cao, Shengde Liu, Ying Guo, Guodong Wang, Yujie Luo, Zeming Zhang, Xuemei Wei, Yingchi Zhao, Tongtong Liu, Xiao Wang, Huawei Xia, Ming Kuang, Qirui Guo, Junhong Li, Luoying Chen, Yibing Wang, Qi Li, Fengchao Wang, Qinghua Liu & Fuping You
Additional file 7: Table S6. The sequence of the crRNAs and gRNAs used in this study.

Additional file 8 of The collateral activity of RfxCas13d can induce lethality in a RfxCas13d knock-in mouse model

Yunfei Li, Junjie Xu, Xuefei Guo, Zhiwei Li, Lili Cao, Shengde Liu, Ying Guo, Guodong Wang, Yujie Luo, Zeming Zhang, Xuemei Wei, Yingchi Zhao, Tongtong Liu, Xiao Wang, Huawei Xia, Ming Kuang, Qirui Guo, Junhong Li, Luoying Chen, Yibing Wang, Qi Li, Fengchao Wang, Qinghua Liu & Fuping You
Additional file 8. Uncropped western blot images.

Additional file 1 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

Emily Haeuser, Audrey L. Serfes, Michael A. Cork, Mingyou Yang, Hedayat Abbastabar, E. S. Abhilash, Maryam Adabi, Oladimeji M. Adebayo, Victor Adekanmbi, Daniel Adedayo Adeyinka, Saira Afzal, Bright Opoku Ahinkorah, Keivan Ahmadi, Muktar Beshir Ahmed, Yonas Akalu, Rufus Olusola Akinyemi, Chisom Joyqueenet Akunna, Fares Alahdab, Fahad Mashhour Alanezi, Turki M. Alanzi, Kefyalew Addis Alene, Robert Kaba Alhassan, Vahid Alipour, Amir Almasi-Hashiani, Nelson Alvis-Guzman … & Laura Dwyer-Lindgren
Additional file 1: Supplemental information.1. Compliance with the Guidlines for Accurate and Transparent Health Estimates Reporting (GATHER). 2. HIV data sources and data processing. 3. Covariate and auxiliary data. 4. Statistical model. 5. References.

Additional file 1 of Mapping age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018

Emily Haeuser, Audrey L. Serfes, Michael A. Cork, Mingyou Yang, Hedayat Abbastabar, E. S. Abhilash, Maryam Adabi, Oladimeji M. Adebayo, Victor Adekanmbi, Daniel Adedayo Adeyinka, Saira Afzal, Bright Opoku Ahinkorah, Keivan Ahmadi, Muktar Beshir Ahmed, Yonas Akalu, Rufus Olusola Akinyemi, Chisom Joyqueenet Akunna, Fares Alahdab, Fahad Mashhour Alanezi, Turki M. Alanzi, Kefyalew Addis Alene, Robert Kaba Alhassan, Vahid Alipour, Amir Almasi-Hashiani, Nelson Alvis-Guzman … & Laura Dwyer-Lindgren
Additional file 1: Supplemental information.1. Compliance with the Guidlines for Accurate and Transparent Health Estimates Reporting (GATHER). 2. HIV data sources and data processing. 3. Covariate and auxiliary data. 4. Statistical model. 5. References.

Additional file 1 of Deep generative model for drug design from protein target sequence

Yangyang Chen, Zixu Wang, Lei Wang, Jianmin Wang, Pengyong Li, Dongsheng Cao, Xiangxiang Zeng, Xiucai Ye & Tetsuya Sakurai
Additional file 1: Figures and Tables of the comparison method.

Additional file 1 of IBIS: identify biomarker-based subgroups with a Bayesian enrichment design for targeted combination therapy

Xin Chen, Jingyi Zhang, Liyun Jiang & Fangrong Yan
Additional file 1. Supplemental simulation results.

Additional file 1 of Cardiovascular magnetic resonance-derived left atrioventricular coupling index and major adverse cardiac events in patients following acute myocardial infarction

Torben Lange, Sören J. Backhaus, Alexander Schulz, Ruben Evertz, Johannes T. Kowallick, Boris Bigalke, Gerd Hasenfuß, Holger Thiele, Thomas Stiermaier, Ingo Eitel & Andreas Schuster
Additional file 1: Figure S1. Kaplan–Meier curves for survival analyses in subgroup of low-risk patients. Left atrioventricular coupling index (LACI) and survival in low-risk patients according to left ventricular ejection fraction (LVEF) after acute myocardial infarction. Incidence of MACE (major adverse cardiac events) according to high and low LACI classified according to Youden Index.

Additional file 1 of Smartphone-assisted training with education for patients with hip and/or knee osteoarthritis (SmArt-E): study protocol for a multicentre pragmatic randomized controlled trial

Franziska Weber, Carsten Müller, Carolin Bahns, Christian Kopkow, Francesca Färber, Paul Gellert, Ina Otte, Horst Christian Vollmar, Werner Brannath, Freya Diederich, Stephan Kloep, Heinz Rothgang, Valerie Dieter, Inga Krauß, Corelien Kloek, Cindy Veenhof, Sandra Collisi, Ute Repschläger, Hannes Böbinger, Christian Grüneberg, Christian Thiel & Dirk Peschke
Additional file 1.

Additional file 1 of Field-measured canopy height may not be as accurate and heritable as believed: evidence from advanced 3D sensing

Jingrong Zang, Shichao Jin, Songyin Zhang, Qing Li, Yue Mu, Ziyu Li, Shaochen Li, Xiao Wang, Yanjun Su & Dong Jiang
Additional file 1: Fig. S1. Canopy height correlations between the field measurement and DAP estimates at different flight heights. (a), (b), (c), and (d) are the results of flight height at 10, 20, 30, and 40m, respectively. The solid line represents the fitted line, and the dashed line represents the 1:1 line. The color bar shows the kernel density value of the point distribution, and the green to yellow represents the increase in kernel density....

Additional file 1 of Epigenetic aging in patients diagnosed with coronary artery disease: results of the LipidCardio study

Verena Laura Banszerus, Maximilian König, Ulf Landmesser, Valentin Max Vetter & Ilja Demuth
Additional file 1. Supplementary Table 1. Correlation table of DNAmAA and potentially confounding variables (Spearman’s r).

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