6 Works
The mitochondrial genome of Chthamalus malayensis (Sessilia: Chthamalidae) and its molecular phylogeny within Cirripedia
Sheng Mao, Tian Ge, Yuefeng Cai, Nanjing Ji, Xue Kong & Xin Shen
Cirripedia is a lower crustacean that has an invaluable place in several aspects of intertidal ecology and anti-fouling research. In this study, we present the first mitochondrial genome of Chthamalus malayensis. The complete mitochondrial genome of C. malayensis is a circular molecule of 15,230 bp. In comparison to the pancrustacean ground pattern, the mitochondrial genome of C. malayensis has a deletion of the trnC gene. Phylogenetic analysis based on mitochondrial protein-coding genes showed that C....
Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment
Yu Wang, Qianmei Wang, Wei Feng, Qian Yuan, Xiaowei Qi, Sheng Chen, Pu Yao, Qing Dai, Peiyuan Xia, Dinglin Zhang & Fengjun Sun
Luteolin (Lut) is a natural flavonoid polyphenolic compound with multiple pharmacological activities, such as anti-oxidant, anti-inflammatory, and anti-tumor effects. However, the poor aqueous solubility and low bioactivity of Lut restrict its clinical translation. Herein, we developed a reactive oxygen species (ROS)-responsive nanoplatforms to improve the bioactivity of Lut. Folic acid (FA) was employed to decorate the nanoparticles (NPs) to enhance its targeting ability. The size of Lut-loaded ROS-responsive nanoparticles (Lut/Oxi-αCD NPs) and FA-modified Lut/Oxi-αCD NPs...
Folic acid-modified ROS-responsive nanoparticles encapsulating luteolin for targeted breast cancer treatment
Yu Wang, Qianmei Wang, Wei Feng, Qian Yuan, Xiaowei Qi, Sheng Chen, Pu Yao, Qing Dai, Peiyuan Xia, Dinglin Zhang & Fengjun Sun
Luteolin (Lut) is a natural flavonoid polyphenolic compound with multiple pharmacological activities, such as anti-oxidant, anti-inflammatory, and anti-tumor effects. However, the poor aqueous solubility and low bioactivity of Lut restrict its clinical translation. Herein, we developed a reactive oxygen species (ROS)-responsive nanoplatforms to improve the bioactivity of Lut. Folic acid (FA) was employed to decorate the nanoparticles (NPs) to enhance its targeting ability. The size of Lut-loaded ROS-responsive nanoparticles (Lut/Oxi-αCD NPs) and FA-modified Lut/Oxi-αCD NPs...
The mitochondrial genome of Chthamalus malayensis (Sessilia: Chthamalidae) and its molecular phylogeny within Cirripedia
Sheng Mao, Tian Ge, Yuefeng Cai, Nanjing Ji, Xue Kong & Xin Shen
Cirripedia is a lower crustacean that has an invaluable place in several aspects of intertidal ecology and anti-fouling research. In this study, we present the first mitochondrial genome of Chthamalus malayensis. The complete mitochondrial genome of C. malayensis is a circular molecule of 15,230 bp. In comparison to the pancrustacean ground pattern, the mitochondrial genome of C. malayensis has a deletion of the trnC gene. Phylogenetic analysis based on mitochondrial protein-coding genes showed that C....
Stress levels among an international sample of pregnant and postpartum women during the COVID-19 pandemic
Diego F. Wyszynski, Sonia Hernandez-Diaz, Vanessa Gordon-Dseagu, Noemi Ramiro & Karestan C. Koenen
Stress is a complex condition that can have a profound effect on an individual’s sense of wellbeing and their ability to live a happy and healthy life. COVID-19 and its associated stressors have the potential to disrupt numerous facets of our everyday lives. Pregnant and postpartum women are especially vulnerable to changes in the availability of routine health and social care services and of their support networks. The current study sought to explore stress levels...
Stress levels among an international sample of pregnant and postpartum women during the COVID-19 pandemic
Diego F. Wyszynski, Sonia Hernandez-Diaz, Vanessa Gordon-Dseagu, Noemi Ramiro & Karestan C. Koenen
Stress is a complex condition that can have a profound effect on an individual’s sense of wellbeing and their ability to live a happy and healthy life. COVID-19 and its associated stressors have the potential to disrupt numerous facets of our everyday lives. Pregnant and postpartum women are especially vulnerable to changes in the availability of routine health and social care services and of their support networks. The current study sought to explore stress levels...
Affiliations
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Massachusetts General Hospital6
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Tianjin Agricultural University2
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Hainan Medical University2
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Sun Yat-sen University2
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Shanghai University2
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West China Hospital of Sichuan University2
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Zhejiang University2
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Xuan Wu Hospital of the Capital Medical University2
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Air Force Medical University2
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Fudan University Shanghai Cancer Center2