Supplemental material, sj-docx-1-cre-10.1177_02692155221136046 for Effect of pelvic floor muscle training on urinary incontinence after radical prostatectomy: An umbrella review of meta-analysis and systematic review by Jia-ming Yang, Hua Ye, Yi Long, Qiang Zhu, Hui Huang, Hui-yong Xie, Yun Luo, Yan-biao Zhong, Jing Chen and Mao-yuan Wang in Clinical Rehabilitation

Supplemental Material for The Serum- and Glucocorticoid-Inducible Kinase 1 (SGK1) as a Novel Therapeutic Target in Mantle Cell Lymphoma by Jiao Li, Hui Yu, Xing Wang, Yingying Ye, Wei Fang, Ning Ding, Lan Mi, Lingyan Ping, Xiaogan Wang, Yuqin Song and Jun Zhu in Cancer Control

Supplemental information

This study evaluated the effect of encapsulated thymol and carvacrol mixture (ETCM) on the growth performance, antioxidant capacity, immune function and intestinal health of broilers. In total, 400 one-day-old male Arbour Acres broilers were randomly allocated to two groups with eight replicates of 25 birds each and fed a basal diet (control) or a basal diet supplemented with 150 mg/kg ETCM. The trial lasted 42 days. ETCM supplementation significantly increased (p < .05) average daily...

This study evaluated the effect of encapsulated thymol and carvacrol mixture (ETCM) on the growth performance, antioxidant capacity, immune function and intestinal health of broilers. In total, 400 one-day-old male Arbour Acres broilers were randomly allocated to two groups with eight replicates of 25 birds each and fed a basal diet (control) or a basal diet supplemented with 150 mg/kg ETCM. The trial lasted 42 days. ETCM supplementation significantly increased (p < .05) average daily...

Additional file 22: Fig. S22. Hematoxylin and eosin (H&E) staining on PDACs. The tumor cell purities of tumor tissues and the non-tumor cell purities of tumor-adjacent tissues.

Supplemental material, sj-pdf-5-imr-10.1177_03000605221134467 for Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis by Peng Wang, Wei Cao, Hong Zhou, Huan Xin Zhang, Lunzhong Zhang, Li Liu, Yunlong Sui, Zhen Zhang, Xiaoyu Yin, Fan Yang and Li Kong in Journal of International Medical Research

The jute/polylactic acid (PLA) composite material has been widely concerned in the field of composite materials because of its green, degradable and renewable properties, but its low mechanical properties limit the application field. In order to improve the mechanical properties of jute/PLA composites, styrene butadiene rubber (SBR) particles modified by different silane coupling agents were introduced into PLA matrix, and jute/PLA composites were prepared by solution casting and molding method. The changes in the mechanical...

supplementary material on the derivation of the forward matrix

Additional file 5. Fig. S32: The host assignment of plant-associated viruses by using BLASTx searching the contigs assembled from the NGS data of each plant species (those containing possible non-plant-infecting virus) against the total mitochondrial proteome database that were downloaded from GenBank.

Two unusual novel iridoid glycosides, cornsecoside A (1) and cornsecoside B (2), were isolated from a 40% ethanol elution fraction of a 50% ethanol extract of Cornus officinalis fruit. Their structures were determined by spectroscopic data analysis combined with hydrolysis and ECD spectroscopy. In addition, compounds 1 and 2 exhibited cytotoxic activity against Bel-7402 cells with IC50 values of 8.12 and 9.31 µM, and were neuroprotective against H2O2-induced SH-SY5Y cell injure at a concentration of...

Supplemental material, sj-docx-1-tag-10.1177_17562848221142913 for Hereditary hemorrhagic telangiectasis with juvenile polyposis syndrome: a case report by Meng-Yu Tao, Kai-Yi Wang, Xin Li, Chen Yu, Qin-Si Wan, Xu Shu, You-Xiang Chen and Wang-Di Liao in Therapeutic Advances in Gastroenterology

Additional file 3: Fig. S3. The impacts of somatic copy number alterations in PDAC cohort, related to Fig. 2. A Bar plots showing pathway enrichment of cis/trans-effect between CNA and protein (left) or phosphoprotein (right). B Distribution of IRF6 status between the younger patients’ group (≤ 60) and the older patients’ group (> 60) (left). The boxplot reveals the comparison of the mRNA (middle) and protein (right) abundance of IRF6 between the younger patients (≤...

Additional file 4: Fig. S4. Characteristics of PDAC patients with KRASG12D mutations. A The volcano plot showing the phosphosites that significantly altered between tumors with KRASG12D and with other types of KRAS mutations. B The heatmap indicating the phosphorylation abundance of RAF1, MAP2K2, MAPK1 across tumors with different KRAS mutations. C Kaplan-Meier curves for overall survival based on the phosphorylation of E2F1 at S364 (left) and based on the TF activity of E2F1 (right). D...

Additional file 5: Fig. S5. Integrated multi-omics features in tumor tissues compared with NATs of the PDAC, related to Fig. 3. A Principal component analysis (PCA) of RNA-Seq (19,992 genes) in 54 tumors and 51 NATs. Red, tumors; blue, NATs. B PCA of 7,399 phosphoproteins in 113 paired samples. Red, tumors; blue, NATs. C A volcano plot showing the results of a two-tailed Student’s t test comparing tumors and NATs at transcriptome level. D A...

Additional file 7: Fig. S7. The expression of phosphotyrosine in PDAC cohort, related to Fig. 3. A. The proportion of phosphorylation sites S, T and Y in tumors and NATs, respectively. B. The comparison of the percentage of phosphorylation sites S, T and Y in Fudan cohort and other gastrointestinal tumor cohorts. C. The scatter plot demonstrating the T/NAT ratio of phosphotyrosine (y axis) and T/NAT ratio of their corresponding proteins (x axis). D. Heatmap...

Additional file 8: Fig. S8. The effects of diabetes on the proteogenomic characteristics of PDAC, related to Fig. 4. A The boxplot representing the comparison of blood glucose concentration between patients with diabetes and without diabetes. B The Kaplan-Meier curves for overall survival based on diabetic patients with or without medical treatment. C The heatmap showing the distribution of 10q25.3 deletion and MTOR mutations across different samples in TCGA cohort. D The bar plot showing...

Additional file 9: Fig. S9. 8p11.22 amplification is associated with PDAC metastasis, related to Fig. 5. A Western blot assays were conducted for detecting ADAM9 protein in PANC-1 cells after si-ADAM9-1 and si-ADMA9-2 knocked down. B The scatter plot depicting the correlation between ADAM9 expression and expression of ADAM9-interacting proteins (Spearman’s correlation). C The scatter plot depicting the correlation between the abundance of SRC and pathways (GSVA score). D The boxplots indicating the protein expression...

Additional file 2. Supplementary Table.

supplementary material on the derivation of the forward matrix

Five extracts of the aerial parts of Aconitum carmichaeli were obtained by different solvent extraction or macroporous adsorption resin purification: ethyl acetate layer extract (EAE), n-butanol layer extract (BuE), water layer extract (WE), extract eluted by 10% ethanol from macroporous resin (10�), extract eluted by 80% ethanol from macroporous resin (80�). Antioxidant activities of the five extracts were determined by ABTS, DPPH, FRAP assays, anti-AChE activities by modified Ellman’s method, in vitro anti-hepatoma activities by...

Chinese shidu parents (bereaved parents over the age of 49 who have lost their only child) are potentially at a high risk of prolonged grief disorder (PGD), posttraumatic stress disorder (PTSD) and insomnia. The current study aimed to estimate three network models in 310 shidu parents who met the ICD-11 criteria for PGD: (1) a PGD network to identify central symptoms; (2) a comorbidity network to explore bridge symptoms between PGD and PTSD; (3) a...

Two new sesquiterpenoids, flammupin A (1) and flammupin B (2), along with two known compounds, enokipodin C (3) and 5,5'-dibuthoxy-2,2'-bifuran (4) were obtained from Flammulina velutipes, an endophytic fungus isolated from the roots of Caulophyllum robustum Maxim. The structures were elucidated by the combination of HR-ESI-MS, NMR, and ECD analyses. Compound 3 exhibited moderate to potent cytotoxicity against A549, HeLa, and SMMC-7721 cells with IC50 values ranged from 3.69 to 11.84 μM.

Diamond is an ultrawide bandgap semiconductor with excellent electronic and photonic properties, which has great potential applications in microelectronic and optoelectronic devices. As an allotrope of diamond, graphene also has many fantastic properties like diamond, which caught much attention in combing them together. In this work, a direct sp3-to-sp2 conversion method was proposed to fabricate graphene layers on single crystal diamond by thermal treatment with Ni film catalyst. By optimizing the conversing conditions, a thin...

Osteoarthritis (OA) is a well-known chronic degenerative joint disease, with multiple changes in the phenotype of chondrocytes. Circular RNAs (circRNAs) have been shown to be involved in various human diseases, including OA. The purpose of this study was to determine the role of circ_0020093 in OA pathological changes in vitro. C28/I2 cells were treated with interleukin-1 beta (IL-1β) to mimic OA pathological conditions. The expression levels of circ_0020093, miR-181a-5p and ETS-related gene (ERG) mRNA were...