Additional file 16: Figure S8. PheWAS meta-analysis results for the trans-ethnic nonHDL-C PGS in UK Biobank and MVP.

Additional file 1: Supplementary Figure 1 for Figure 2A (SIRT1), 2B (EZH2) and 2C (RUNX3) expression in keloid and normal tissue: this figure is full image of western blots combines with marker. Supplementary Figure 2 for Figure 3A (SIRT1, EZH2 and RUNX3) expression in Human Keloid fibroblast and Human fibroblasts: this figure is full image of western blots combines with marker. Supplementary Figure 3 for Figure 4 (RUNX3 and β-actin) expression after Transfection: this figure...

Additional file 31: Supplementary Note. Supplementary Note and Cohort Acknowledgments.

Additional file 1 Figure on histograms of some simulated abundances vs. true abundances.

Additional file 1 Figure on histograms of some simulated abundances vs. true abundances.

Additional file 1: Supplementary Table 1. The baseline difference between responders and non-responders according to TyG index. Supplementary Table 2. The coefficients and P values for each variable entered into the multivariable logistical analysis in Model 3.

Additional file 1: Supplementary Table 1. The baseline difference between responders and non-responders according to TyG index. Supplementary Table 2. The coefficients and P values for each variable entered into the multivariable logistical analysis in Model 3.

Additional file 24: Figure S9. Comparison of effect size estimates between males and females for index variants showing a significant difference in effect size between sexes.

Additional file 1: Supplementary Table 1. Components of the Dietary Inflammatory Index available in the WHI food frequency questionnaire*. Supplementary Table 2. Test for interaction between the dietary inflammatory index and obesity. Supplementary Table 3. Comparison of descriptive characteristics of women with different BMI categories.

Additional file 2: Supplement 2. Logistic regression results (survey analysis).

Additional file 1: Supplementary Figure 1. The flow chart of the inclusion for patients.

Additional file 1: Table S1-S3. Table S1: Quantitative RT-PCR primer sequences. Table S2: The results of GO TERM_BP enrichment analysis. Table S3: The results of KEGG_PATHWAY enrichment analysis.

Additional file 3: Table S1: Clinical features of congenital hemangioma

Supplemental Material for Prevalence and associating variables with fear of progression in Chinese pediatric cancer patients: A cross-sectional study by Ping Zhang, Meng Zhang, Qian Qu, Wanting Hu, Joseph Torres, Juan Yao, and Xiaorong Pan Hodge in Journal of Child Health Care

The constituents of Ceratocarpus arenarius L., as a traditional anticancer medicine of Kazakh, were firstly profiled with UHPLC-QTOF-MS/MS. The potential compounds against EGFR-TK were virtually screened. As a result, forty-four compounds were analyzed, including 18 flavonoids, 8 steroids, 4 phenolic acids, 9 fatty acids, 1 coumarin and 4 other compounds. Among them, 9 flavonoids, N-trans-Feruloyltyramine (5), stigmasterol (11) and carthamone (38) were recognized as potential key anti-tumor constituents of C. arenarius through docking to active...

Pseudorabies (PR) is an acute infectious disease caused by pseudorabies virus (PRV). There are no available drugs due to the emergence of variant of PRV. Dihydromyricetin (DMY) is a flavonoid extracted from Ampelopsis grossedentata (A. grossedentata), which has a variety of pharmacological activities. In this study, we aim to investigate the in vitro anti-PRV activity of DMY extracted from A. grossedentata. MTT assay was used to detect the cytotoxicity and antiviral activity of DMY. The...

figures of the result of the rest animals and humans

Additional file 1: Table S1. Comparison of characteristics between target population in 2009 and 2015.

Supplemental material, sj-docx-1-mdm-10.1177_0272989X221141381 for Mimicking Clinical Trials Using Real-World Data: A Novel Method and Applications by Wei-Jhih Wang, Aasthaa Bansal, Caroline Savage Bennette and Anirban Basu in Medical Decision Making

Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and evolutionary features. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we quantify hypoxia in 1188 tumours spanning...

The supporting material contains data and theoretical derivations that are not given in the manuscript, and it is a supplement to this work.

Drowned victims possibly obtain various pathogens from drowning sites. Using drowned renal donors to expand the donor pool still lacks consensus due to the potential risk of disease transmission. This retrospective study enrolled 38 drowned donor renal recipients in a large clinical center from August 2012 to February 2021. A 1:2 matched cohort was generated with donor demographics, including age, gender, BMI, and ICU durations. Donor microbiological results, recipient perioperative infections, and early post-transplant and...

Additional file 1: Supplementary results of gene differential analysis and functional enrichment analysis for asthenozoospermia.

Additional file 1: Supplementary results of gene differential analysis and functional enrichment analysis for asthenozoospermia.

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the...