Supplementary Material 1

Additional file 4: Supplementary Table 1. List of top 5 candidates of RalA-interacting proteins that were identified by co-immunoprecipitation and MS. Supplementary Table 2. ZDOCK used to predict the binding sites of RalA and ANXA2. Supplementary Table 3. The sequences of the primers. Supplementary Table 4. The antibodies applied in this study.

To explore the distribution law of traditional Chinese medicine (TCM) syndrome types in patients with psoriasis vulgaris complicated by metabolic disorders based on the same pathogenic factors as blood-heat and blood-stasis in the pathogenesis of psoriasis and metabolic disorders and to further analyze the correlation between adiponectin and the distribution law. From 1 January 2018 to 31 December 2019, patients diagnosed with psoriasis in the inpatient or outpatient department of Dermatology Ward of Shanghai Yueyang...

Additional file 3: Table S2. The number of paired ends reads for the ferret lung samples.

Supplementary information

The molecular signature response classifier (MSRC) predicts tumor necrosis factor-ɑ inhibitor (TNFi) non-response in rheumatoid arthritis. This study evaluates decision-making, validity, and utility of MSRC testing. This comparative cohort study compared an MSRC-tested arm (N = 627) from the Study to Accelerate Information of Molecular Signatures (AIMS) with an external control arm (N = 2721) from US electronic health records. Propensity score matching was applied to balance baseline characteristics. Patients initiated a biologic/targeted synthetic disease-modifying...

When used in clinical trial adaptive designs, conditional power (CP) is most commonly calculated assuming the current trend, but this approach has been criticized for substantially deviating from the actual CP due to “double-dipping” the interim data (i.e., using the interim data as part of the final analysis test statistic and as the assumption for the remainder of the trial). By contrast, CP assuming the design assumption preserves the shape of the CP curve by...

Thermal ablation is widely used in the treatment of lung cancer and is beneficial for the overall survival of patients in clinic. However, there is barely a priority in which ablation system should be chosen under different periods of tumor progression in lung cancer. The present study investigated different modes of thermal ablation systems in mice with transplanted Lewis lung carcinoma tumors and their various biological effects in local regions using untargeted metabolomics. The results...

Thermal ablation is widely used in the treatment of lung cancer and is beneficial for the overall survival of patients in clinic. However, there is barely a priority in which ablation system should be chosen under different periods of tumor progression in lung cancer. The present study investigated different modes of thermal ablation systems in mice with transplanted Lewis lung carcinoma tumors and their various biological effects in local regions using untargeted metabolomics. The results...

Three previously undescribed aromatic diglycosides (1, 5, and 8) and six known analogs (2–4, 6, 7, and 9) were isolated from the roots and rhizomes of Sophora tonkinensis Gagnep. Their structures were elucidated by detailed spectroscopic analysis. The absolute configuration of compound 8 was determined by comparing the experimental and TDDFT calculated ECD spectra of 8 and aglycone 8a. Furthermore, a multistep conformer filtering procedure for TDDFT calculation of flexible glycoside was proposed, which afforded...

Whether hemostatic status was correlated with the diverse types of acute kidney injury in cirrhotic patients is unclear. The present study aimed to investigate the relationship between hemostatic markers and the diverse types of acute kidney injury (AKI) in liver cirrhosis. Cirrhotic patients with consecutive treatment at the First Affiliated Hospital of Medicine School, Zhejiang University, were pooled in a cohort. Their demographic and clinical data, biochemistry parameters and hemostatic markers were assessed to identify...

The integration of nanofiltration with catalysis enables high-efficient removal of micropollutants due to its remarkable high selectivity and superior degradation efficacy. Meanwhile, the catalysis-assisted nanofiltration can largely alleviate the issues of inferior low-molecular-weight micropollutants selectivity, membrane fouling and tradeoff limitation. Two different technical routes, catalytic coupled nanofiltration system and catalytic nanofiltration membrane, have been developed based on nanofiltration module and material design for micropollutants separation enhancement. In this review, we first summarize the underlying governing...

Additional file 1: Figure S1. DLS analysis of F68@TA prepared by different mass ratio of F68 and TA. (n=3). Figure S2. TEM images of F68@TA@Ag NPs prepared with different content of AgNO3. Figure S3. (A) Size distributions and (B) zeta potentials of F68@TA, F68@TA/CDDP, and AINR solutions. Figure S4. Tyndall Effects of F68@TA/CDDP solution at different pHs for 1 h. Figure S5. DLS analysis of F68@TA/CDDP treated with PBS at different pHs for 48 h....

Additional file 1.

Additional file 1: Table S1. Intergroup differences in demographics, health conditions, and living habits. Table S2. Intergroup differences in detailed items of leisure activities. Table S3. Results of the relative importance of influencing factors to each cognitive domain in the full sample (N = 1347). Table S4. Estimated direct and indirect effects of the grouped sample (N = 583) SEM with ECR, LLA, and four cognitive domains as latent factors. Table S5. Estimated direct and...

Supplementary information

Additional file 2. Pre-course knowledge assessment of the learners

Supplementary Material 1

Supplementary Material 1

Additional file 1: Figure S1. Sex-stratified Clinical and Functional Measures in (A) Females and (B) Males with handgrip strengthdata. Values in red correspond to mean handgrip strength. * Corresponds to a statistically significant (p< 0.05)difference between participants with COPD and smoking controls.

Additional file 1. RHC and BPA procedure.

Supplemental material, sj-pdf-4-jva-10.1177_11297298221139640 for Risk factors for in-stent restenosis in maintenance hemodialysis patients with central venous occlusive disease and biomechanical assessment of stents by Yang Yu, Yuqin Xiong, Tao Li, Jingyuan Zhou, Weijie Yan, Yan Xiong, Yu Chen and Ping Fu in The Journal of Vascular Access

Supplemental material, sj-docx-1-tag-10.1177_17562848221142913 for Hereditary hemorrhagic telangiectasis with juvenile polyposis syndrome: a case report by Meng-Yu Tao, Kai-Yi Wang, Xin Li, Chen Yu, Qin-Si Wan, Xu Shu, You-Xiang Chen and Wang-Di Liao in Therapeutic Advances in Gastroenterology

Glioblastoma multiforme (GBM) is the most aggressive and deadliest type of brain tumor with a > >th he most aggressive and deadliest type of brain tumor witnear-infrared fluorescent dye, but it is hard to directly target brain tumor. Therefore, our study aimed to develop a new carrier for ICG to accurately visualize cancer tissue during surgery. Exosomes were isolated from culture U-87 MG cells, then loaded with Indocyanine green (ICG) and conjugated with RGERPPR peptide...

Additional file 1. Table S1: Median fluid accumulation through Day 14, in the modified intention to treat population, stratified by subgroups. Table S2: The effect of accelerated vs standard RRT strategy on outcomes across deciles of baseline fluid balance. Table S3: The effect of accelerated vs standard RRT strategy on outcomes in patients with ≤ or > 10% fluid overload at baseline.