346 Works

Effect of exogenous melatonin on salt stress in cucumber: alleviating effect and molecular basis

Tingting Liu, Guoming Xing, Zhifeng Chen, Xijiao Zhai, Xuyang Wei, Chen Wang, Tianmeng Li & Shaowen Zheng
Cucumber (Cucumis sativus L.) is sensitive to the salinization of environment. Soil salinization in facility environment affects the yield and quality of cucumber. Melatonin (N-acetyl-5-methoxytryptamine) is an effective free radical scavenger in plants and could effectively alleviate the abiotic stress injury of plants. In this study, we investigated the effect of different concentrations of exogenous melatonin in mitigating salt stress in cucumber and some underlying molecular mechanisms. The results indicated that 100 μmol/L melatonin-treated plants...

Additional file 1 of Multiparametric liver MRI for predicting early recurrence of hepatocellular carcinoma after microwave ablation

Zhaohe Zhang, Jie Yu, Sisi Liu, Linan Dong, Tiefang Liu, Haiyi Wang, Zhiyu Han, Xiaojing Zhang & Ping Liang
Additional file 1.

Additional file 2 of A unified global genotyping framework of dengue virus serotype-1 for a stratified coordinated surveillance strategy of dengue epidemics

Liqiang Li, Xiang Guo, Xiaoqing Zhang, Lingzhai Zhao, Li Li, Yuji Wang, Tian Xie, Qingqing Yin, Qinlong Jing, Tian Hu, Ziyao Li, Rangke Wu, Wei Zhao, Sherman Xuegang Xin, Benyun Shi, Jiming Liu, Shang Xia, Zhiqiang Peng, Zhicong Yang, Fuchun Zhang, Xiao-Guang Chen & Xiaohong Zhou
Additional file 2. Characteristics of 5003 DENV-1 isolates worldwide from 1944 to 2018 inclusive in this study.

Additional file 1 of A unified global genotyping framework of dengue virus serotype-1 for a stratified coordinated surveillance strategy of dengue epidemics

Liqiang Li, Xiang Guo, Xiaoqing Zhang, Lingzhai Zhao, Li Li, Yuji Wang, Tian Xie, Qingqing Yin, Qinlong Jing, Tian Hu, Ziyao Li, Rangke Wu, Wei Zhao, Sherman Xuegang Xin, Benyun Shi, Jiming Liu, Shang Xia, Zhiqiang Peng, Zhicong Yang, Fuchun Zhang, Xiao-Guang Chen & Xiaohong Zhou
Additional file 1. Supplementary Figures and tables for this study.

Additional file 3 of A unified global genotyping framework of dengue virus serotype-1 for a stratified coordinated surveillance strategy of dengue epidemics

Liqiang Li, Xiang Guo, Xiaoqing Zhang, Lingzhai Zhao, Li Li, Yuji Wang, Tian Xie, Qingqing Yin, Qinlong Jing, Tian Hu, Ziyao Li, Rangke Wu, Wei Zhao, Sherman Xuegang Xin, Benyun Shi, Jiming Liu, Shang Xia, Zhiqiang Peng, Zhicong Yang, Fuchun Zhang, Xiao-Guang Chen & Xiaohong Zhou
Additional file 3. Features of the selected 910 E complete sequences for temporal phylogenic reconstruction covering all spatio-temporal distributions and representing all designated subgenotypes and clades in genotypes I, IV, and V from 5003 DENV-1 strains worldwide.

sj-doc-1-tau-10.1177_17562872221128473 – Supplemental material for Furosemide improves the stone clearance rate of extracorporeal shockwave lithotripsy for kidney stones but not ureteral stones: a systematic review and meta-analysis

Feng Yao, Ke Li, ShiQuan Huang, XueSong Cheng & XiaoLiang Jiang
Supplemental material, sj-doc-1-tau-10.1177_17562872221128473 for Furosemide improves the stone clearance rate of extracorporeal shockwave lithotripsy for kidney stones but not ureteral stones: a systematic review and meta-analysis by Feng Yao, Ke Li, ShiQuan Huang, XueSong Cheng and XiaoLiang Jiang in Therapeutic Advances in Urology

Supplemental Material - Construction of a Carcinoembryonic Antigen Surface-Enhanced Raman Spectroscopy (SERS) Aptamer Sensor Based on the Silver Nanorod Array Chip

Rui Li, Lijun Li, Yan Zhang, Xin Lin, Heyuanxi Guo, Chubing Lin & Jun Feng
Supplemental Material for Construction of a Carcinoembryonic Antigen Surface-Enhanced Raman Spectroscopy (SERS) Aptamer Sensor Based on the Silver Nanorod Array Chip by Rui Li, Lijun Li, Yan Zhang, Xin Lin, Heyuanxi Guo, Chubing Lin, and Jun Feng in Applied Spectroscopy

Additional file 1 of Predictive worth of estimated glucose disposal rate: evaluation in patients with non-ST-segment elevation acute coronary syndrome and non-diabetic patients after percutaneous coronary intervention

Chi Liu, Xiaoli Liu, Xiaoteng Ma, Yujing Cheng, Yan Sun, Dai Zhang, Qi Zhao & Yujie Zhou
Additional file 1: Table S1. Unadjusted Cox regression analysis investigating predictors of MACCE. Figure S1. Calculation of Gensini score of representative case.

Additional file 1 of A simplified multiplex methylated DNA testing for early detection of colorectal cancer in stool DNA

Yanmiao Dai, Guodong Zhao, Jun Yang, Xilang Zhou, Shangmin Xiong, Xirong Lu, Liming Gao, Jianfang Wu, Zouhua Xu, Sujuan Fei, Minxue Zheng & Hongwei Xu
Additional file 1: Supplemental Figure.

Additional file 3 of Gastric cancer-derived exosomal miR-519a-3p promotes liver metastasis by inducing intrahepatic M2-like macrophage-mediated angiogenesis

Shengkui Qiu, Li Xie, Chen Lu, Chao Gu, Yiwen Xia, Jialun Lv, Zhe Xuan, Lang Fang, Jing Yang, Lu Zhang, Zheng Li, Weizhi Wang, Hao Xu, Bowen Li & Zekuan Xu
Additional file 3.

Additional file 1 of Comprehensive characterization of ubiquitinome of human colorectal cancer and identification of potential survival-related ubiquitination

Wei Zhang, Yan Yang, Liewen Lin, Jingquan He, Jingjing Dong, Bin Yan, Wanxia Cai, Yumei Chen, Lianghong Yin, Donge Tang, Fanna Liu & Yong Dai
Additional file 1: Figure S1. The length of all identified ubiquitinated peptides. Figure S2. The numbers of all identified spectrums, peptides and proteins. Figure S3. The screening of potential functional ubiquitination in CRC patients.

DFT study on Fe and N decorated graphene as the drug delivery system for β-lapachone anticancer drug

Wei Zhang
The β-lapachone anticancer drug performs efficiently in preventing the growth of cancer cells. Transporting the pharmaceutical compound to its target cell is a hot topic in target-direct treatment. Here, we propose a new kind of drug delivery, Fe and N decorated graphene (Fe-N-Graphene), based on density functional theory, showing high performance in the transportation of β-lapachone anticancer drugs. Results indicate Fe-N-Graphene exhibits high adsorption energies of 1.67–1.73 eV for β-lapachone molecules, which guarantees stability during...

Additional file 1 of Identification of DNA methylation-regulated genes as potential biomarkers for coronary heart disease via machine learning in the Framingham Heart Study

Xiaokang Zhang, Chen Wang, Dingdong He, Yating Cheng, Li Yu, Daoxi Qi, Boyu Li & Fang Zheng
Additional file 1: Table S1. Performance of the expression and methylation models applied to datasets from GEO. Table S2. Clinical baseline information of participants in the transcriptome sequencing and methylation microarray.

Supplemental Material - Functional Limitations and Physical Health in Community-Dwelling Medicare Advantage Beneficiaries: Variation by Race and Hispanic Subgroup

Jeff Luck, Diana Govier, Lan N. Ðoàn, Shyama Mahakalanda, Wei Zhang & Carolyn Mendez-Luck
Supplemental Material for Functional Limitations and Physical Health in Community-Dwelling Medicare Advantage Beneficiaries: Variation by Race and Hispanic Subgroup by Jeff Luck, Diana Govier, Lan N. Ðoàn, Shyama Mahakalanda, Wei Zhang, and Carolyn Mendez-Luck in Journal of Aging and Health

The feasibility of one-stage flexible ureteroscopy lithotripsy in solitary kidney patients with 1–3 cm renal stones and risk factors of renal function changes

Yang Pan, Han Chen, Hualin Chen, Xiaoxiang Jin, Yunxiao Zhu & Gang Chen
To compare perioperative outcomes and long-term renal function changes between prior stenting (PS) and not prior stenting (NPS) before flexible ureteroscopy lithotripsy (f-URS) for solitary kidney patients. Solitary kidney patients with 10–30 mm renal stones were enrolled in this historical control study. Perioperative parameters and complications were compared. Stone-free was defined as the absence of any residual stones on a CT scan. Renal function changes were evaluated by estimated glomerular filtration rate (eGFR) and adjusted...

Specific alterations in gut microbiota in patients with chronic kidney disease: an updated systematic review

Jin Zhao, Xiaoxuan Ning, Baojian Liu, Ruijuan Dong, Ming Bai & Shiren Sun
Emerging evidence demonstrates that gut dysbiosis is implicated in the pathogenesis of chronic kidney disease (CKD) with underlying mechanisms involving mucosal and/or systematic immunity or metabolic disorders. However, the profile of gut microbiota in patients with CKD has not been completely explored. Databases from their date of inception to 31 March 2020 were systematically searched for case-control or cross-sectional studies comparing the gut microbial profiles in adult patients with CKD or end-stage renal disease (ESRD)...

Additional file 1 of Comparison of transvaginal cervical cerclage versus laparoscopic abdominal cervical cerclage in cervical insufficiency: a retrospective study from a single centre

Guiqiong Huang, Chunyan Deng, Hua Liao, Qing Hu, Haiyan Yu & Xiaodong Wang
Supplementary Material 1

Additional file 3 of Simplified regimen of combined low-dose rituximab for autoimmune encephalitis with neuronal surface antibodies

Ying Du, Chao Zhao, Juntong Liu, Chuan Li, Qi Yan, Lin Li, Yunfeng Hao, Dan Yao, Huaxing Si, Yingjun Zhao & Wei Zhang
Additional file 3: Table S3. Comparison of clinical outcomes between early and delayed initiation of rituximab subgroups in rituximab cohort

Additional file 2 of Simplified regimen of combined low-dose rituximab for autoimmune encephalitis with neuronal surface antibodies

Ying Du, Chao Zhao, Juntong Liu, Chuan Li, Qi Yan, Lin Li, Yunfeng Hao, Dan Yao, Huaxing Si, Yingjun Zhao & Wei Zhang
Additional file 2: Table S2. Comparison of clinical outcomes between single first-line and repeated first-line treatment subgroups in rituximab cohort

Additional file 1 of Effectiveness of inactivated and Ad5-nCoV COVID-19 vaccines against SARS-CoV-2 Omicron BA. 2 variant infection, severe illness, and death

Zhuoying Huang, Shuangfei Xu, Jiechen Liu, Linlin Wu, Jing Qiu, Nan Wang, Jia Ren, Zhi Li, Xiang Guo, Fangfang Tao, Jian Chen, Donglei Lu, Xiaodong Sun & Weibing Wang
Additional file 1: Table S1. The definitions of the variables. Table S2. Vaccine effectiveness of Ad5-vectored vaccine against documented SARS-CoV-2 infection, severe or critical illness and death in matched case-control analysis. Table S3. Sensitivity analysis for vaccine effectiveness of any vaccine in matched case-control assuming exposure window 7 days prior to onset date. Table S4. Sensitivity analysis for vaccine effectiveness of inactivated vaccines in matched case-control analysis assuming exposure window 7 days prior to onset...

Additional file 1 of Molecular characteristics of global β-lactamase-producing Enterobacter cloacae by genomic analysis

Jincao Hu, Jia Li, Chang Liu, Yan Zhang, Hui Xie, Chuchu Li, Han Shen & Xiaoli Cao
Additional file 1.

Additional file 2 of In-hospital initiation of PCSK9 inhibitor and short-term lipid control in patients with acute myocardial infarction

Bowen Lou, Hui Liu, Yongbai Luo, Gulinigaer Tuerhong Jiang, Haoyu Wu, Chen Wang, Yue Wu, Bo Zhou, Zuyi Yuan, Jianqing She & Junhui Liu
Additional file 2: Fig. S2. Jitter and hist plots (triple therapy-based PSM).

Additional file 1 of Bifunctional anti-PD-L1/TGF-βRII agent SHR-1701 in advanced solid tumors: a dose-escalation, dose-expansion, and clinical-expansion phase 1 trial

Dan Liu, Jun Zhou, Yongsheng Wang, Mingjun Li, Haiping Jiang, Yunpeng Liu, Xianli Yin, Minghua Ge, Xiaojun Xiang, Jieer Ying, Jian Huang, Yan-qiao Zhang, Ying Cheng, Zhigang Huang, Xianglin Yuan, Weiqing Han, Dong Yan, Xinshuai Wang, Pan Liu, Linna Wang, Xiaojing Zhang, Suxia Luo, Tianshu Liu & Lin Shen
Additional file 1: Figure S1. Study design. Figure S2. Tumor response of patients in the dose-escalation and dose-expansion phase. Figure S3. Percentage change from baseline in target lesion tumour burden over time in patients with select tumors at the recommended dose (30 mg/kg q3w). Figure S4. Receiver operating characteristic curve analysis of pSmad2 level in tumor cells for ORR per RECIST v1.1. Table S1. Pharmacokinetic parameters following a single infusion. Table S2. Summary of treatment-related...

Additional file 3 of In-hospital initiation of PCSK9 inhibitor and short-term lipid control in patients with acute myocardial infarction

Bowen Lou, Hui Liu, Yongbai Luo, Gulinigaer Tuerhong Jiang, Haoyu Wu, Chen Wang, Yue Wu, Bo Zhou, Zuyi Yuan, Jianqing She & Junhui Liu
Additional file 3: Table. S1. Summary of statin plus evolocumab therapy-based PSM.

Emerging pharmacologic interventions for pre-eclampsia treatment

Xiao Zhang, Yue Chen, Dongli Sun, Xiaojun Zhu, Xia Ying, Yao Yao, Weidong Fei & Caihong Zheng
Pre-eclampsia is a serious pregnancy complication and a major global concern for the mortality of both mother and fetus. Existing symptomatic treatments do not delay disease progression; thus, timely delivery of the baby is the most effective measure. However, the risk of various maternal and fetal injuries remains. In this review, we summarize potential strategies for pharmacologic interventions in pre-eclamptic therapy. Specifically, we discuss the pathophysiological process of various effective candidate therapeutics that act on...

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  • Agricultural University of Hebei
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  • Chinese Academy of Medical Sciences & Peking Union Medical College
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  • Chinese Academy of Sciences
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