49 Works

A closer look at Malaita's lithics. Preliminary results of a functional study of the lithic tools from Apunirereha and Ria, Solomon Islands

Julia Tomasso & Johannes Moser
Journal of Global Archaeology, 2020

Bibliopol@: The Book Market in the Renaissance between France and the Low Countries

Renaud Adam & Chiara Lastraioli

Validation of a French-language version of TeamSTEPPS® T-TPQ and T-TAQ questionnaires

Anh Nguyet Diep, Méryl Paquay, Jean-Christophe Servotte, Nadia Dardenne, Laure Istas, Pauline Van Ngoc, Mathilde Charlier, Alexandre Ghuysen & Anne-Françoise Donneau
Teamwork training and evaluation are essential to enhance safety and quality of care. The lack of the psychometric testing of the TeamSTEPPS® Teamwork Attitudes Questionnaire (T-TAQ) and Teamwork Perceptions Questionnaire (T-TPQ) across different language and cultural settings has questioned their widespread use because such attitudes and perceptions are highly subjective and context-bound. The present study aims to translate the T-TAQ and T-TPQ into the French language and validate the psychometric properties of the two questionnaires...

Additional file 15 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 15: Fig. S6. Sensitivity analysis: impact of the number of initialization on the canalization results during the Monte Carlo. The percentage of random initialization reaching each attractor is displayed with the Sox9 positive state (healthy) in orange, the Runx2 positive state in blue and the None in grey. Data labels indicate the absolute amount of state reaching the attractors. None of initializations reached an alternative attractor, even for higher amount of random initializations...

Additional file 16 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 16: Fig. S7. Pseudo-time evolution of variables during simulations. The sequence of variable updating over each time steps after introducing a perturbation from the healthy state was saved as a timeseries and plotted. It shows the discrete behavior of the simulation and that a steady state is reached way before the duration of the perturbation (1000 time steps) is reached in such a way that maintain the perturbation longer would not change the...

Additional file 1 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 1: Table S1. Definitions. Definitions of technical terms pertaining to biological signaling network modeling with a semi-quantitative additive formalism.

Additional file 7 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 7: Table S3. Validation of transcriptional data-inferred regulatory interactions. Transcriptional interactions were inferred from the merged OA dataset. Inference was run with three algorithms and only interactions that were present in the results of the three algorithms (GENIE3, ARACNE, TIGRESS) were considered as additions to the model. An interaction was considered present for one algorithm if it scored higher than a threshold defined as the difference between the mean and standard deviation of...

Additional file 7 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 7: Table S3. Validation of transcriptional data-inferred regulatory interactions. Transcriptional interactions were inferred from the merged OA dataset. Inference was run with three algorithms and only interactions that were present in the results of the three algorithms (GENIE3, ARACNE, TIGRESS) were considered as additions to the model. An interaction was considered present for one algorithm if it scored higher than a threshold defined as the difference between the mean and standard deviation of...

Additional file 10 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 10: Fig. S2. Effect of ALKs ratio in the influence of inflammation and TGFβ signaling on chondrocyte hypertrophy. Percentage of perturbations remaining in the healthy state (right) or transitioning towards the hypertrophic one (left) during inflammatory pathway activation with TGF-B treatment while changing the ratio between ALK1 and ALK5. The inflammatory and TGF-B profiles that were imposed are the same as in Fig. 4A except that the value imposed for ALK1 and ALK5...

Additional file 13 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 13: Fig. S4. Decision tree summarizing the variable updating scheme employed in algorithm to simulate the in silico chondrocyte. Each biological component is represented by the gene expression level (slow variable) and the protein activity potential (fast variable). Variables are updated based on the rules stored in the model’s equations. First, fast variables are updated in random order, when a pseudo-stable state is reached and that all fast variables have been updated, the...

Additional file 1 of In silico optimization of RNA–protein interactions for CRISPR-Cas13-based antimicrobials

Ho-min Park, Yunseol Park, Urta Berani, Eunkyu Bang, Joris Vankerschaver, Arnout Van Messem, Wesley De Neve & Hyunjin Shim
Additional file 1. Supplementary Figures S1–S15 and Supplementary Tables S1–S17.

Observation on the effect of platelet-rich plasma combined with drugs in the treatment of herpes zoster neuralgia

Zenghua Zhou, Xin Hu, Fangran Yan, Yanhua Zhou, Ruilin He, Xiaolong Ye & Zongbin Jiang
To observe the effect of ultrasound-guided platelet-rich plasma (PRP) injection in the treatment of herpes zoster neuralgia (HZN). Eighty patients with HZN were randomly divided into observation group and control group, with 40 cases in each group. The observation group was treated with ultrasound-guided PRP injection of target nerves combined with drugs. The control group was treated with drugs alone. The pain scores of before treatment (T0), and 1 week (T1), 1 month (T2), 3...

sj-docx-1-jdr-10.1177_00220345221123256 – Supplemental material for TRAF3IP2–IL-17 Axis Strengthens the Gingival Defense against Pathogens

J. Zhang, L. Sun, M.H.H. Withanage, S.M. Ganesan, M.A. Williamson, J.T. Marchesan, Y. Jiao, F.R. Teles, N. Yu, Y. Liu, D. Wu, K.L. Moss, A.K. Mangalam, E. Zeng, Y.L. Lei & S. Zhang
Supplemental material, sj-docx-1-jdr-10.1177_00220345221123256 for TRAF3IP2–IL-17 Axis Strengthens the Gingival Defense against Pathogens by J. Zhang, L. Sun, M.H.H. Withanage, S.M. Ganesan, M.A. Williamson, J.T. Marchesan, Y. Jiao, F.R. Teles, N. Yu, Y. Liu, D. Wu, K.L. Moss, A.K. Mangalam, E. Zeng, Y.L. Lei and S. Zhang in Journal of Dental Research

sj-docx-1-cre-10.1177_02692155231152567 - Supplemental material for Effect of robot-assisted gait training on quality of life and depression in neurological impairment: A systematic review and meta-analysis

Meike den Brave, Charlotte Beaudart, Benoit Maertens de Noordhout, Vincent Gillot & Jean-Francois Kaux
Supplemental material, sj-docx-1-cre-10.1177_02692155231152567 for Effect of robot-assisted gait training on quality of life and depression in neurological impairment: A systematic review and meta-analysis by Meike den Brave, Charlotte Beaudart, Benoit Maertens de Noordhout, Vincent Gillot and Jean-Francois Kaux in Clinical Rehabilitation

Indian philosophy and the value of transformative experiences. An interview with Monima Chadha by Edvard Avilés and Matthieu Koroma

Monima Chadha, Edvard Avilés & Matthieu Koroma
In this interview, we engage in a cross-cultural discussion about the diversity of consciousness. Indian philosophy can seem quite cryptic and difficult to follow because it is a primary oral tradition. However, Monima Chadha has developed a series of work aiming at introducing the rich insights of Indian philosophy of mind into Western literature. Indeed, the translation of concepts and practices from the Indian to the Western context requires a solid knowledge of the Indian...

Observation on the effect of platelet-rich plasma combined with drugs in the treatment of herpes zoster neuralgia

Zenghua Zhou, Xin Hu, Fangran Yan, Yanhua Zhou, Ruilin He, Xiaolong Ye & Zongbin Jiang
To observe the effect of ultrasound-guided platelet-rich plasma (PRP) injection in the treatment of herpes zoster neuralgia (HZN). Eighty patients with HZN were randomly divided into observation group and control group, with 40 cases in each group. The observation group was treated with ultrasound-guided PRP injection of target nerves combined with drugs. The control group was treated with drugs alone. The pain scores of before treatment (T0), and 1 week (T1), 1 month (T2), 3...

Additional file 5 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 5: Fig. S1. Individual dataset clustering and heatmap. The microarray sub-datasets, used in the merged dataset, were also investigated individually. They were pre-processed (i.e. processing steps before merging and correcting for batch effect) in the same way as the merged dataset but the unsupervised clustering analysis was done on each sub-dataset separately in order to compare the biological or OA related information content before and after the data merging. The heatmaps show the...

Additional file 11 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 11: Fig. S3. Screenshot of the user-friendly interface for the virtual chondrocytes App. The standalone Matlab-based applications can be launched and used without Matlab license, provided that the compiler Matlab Runtime is installed ( https://nl.mathworks.com/products/compiler/matlab-runtime.html ). The virtual chondrocyte initial state can be set as healthy or hypertrophic, allowing the user to test any scenarios. All the 60 components may be perturbed alone or in any sort of combination by forcing the variables...

sj-docx-1-cre-10.1177_02692155231152567 - Supplemental material for Effect of robot-assisted gait training on quality of life and depression in neurological impairment: A systematic review and meta-analysis

Meike den Brave, Charlotte Beaudart, Benoit Maertens de Noordhout, Vincent Gillot & Jean-Francois Kaux
Supplemental material, sj-docx-1-cre-10.1177_02692155231152567 for Effect of robot-assisted gait training on quality of life and depression in neurological impairment: A systematic review and meta-analysis by Meike den Brave, Charlotte Beaudart, Benoit Maertens de Noordhout, Vincent Gillot and Jean-Francois Kaux in Clinical Rehabilitation

sj-docx-1-jdr-10.1177_00220345221123256 – Supplemental material for TRAF3IP2–IL-17 Axis Strengthens the Gingival Defense against Pathogens

J. Zhang, L. Sun, M.H.H. Withanage, S.M. Ganesan, M.A. Williamson, J.T. Marchesan, Y. Jiao, F.R. Teles, N. Yu, Y. Liu, D. Wu, K.L. Moss, A.K. Mangalam, E. Zeng, Y.L. Lei & S. Zhang
Supplemental material, sj-docx-1-jdr-10.1177_00220345221123256 for TRAF3IP2–IL-17 Axis Strengthens the Gingival Defense against Pathogens by J. Zhang, L. Sun, M.H.H. Withanage, S.M. Ganesan, M.A. Williamson, J.T. Marchesan, Y. Jiao, F.R. Teles, N. Yu, Y. Liu, D. Wu, K.L. Moss, A.K. Mangalam, E. Zeng, Y.L. Lei and S. Zhang in Journal of Dental Research

Additional file 2 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 2. Supplementary computational method. Equations, mathematical framework and justification of deviation from the general rule in the equations.

Additional file 2 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 2. Supplementary computational method. Equations, mathematical framework and justification of deviation from the general rule in the equations.

Additional file 3 of An integrated in silico-in vitro approach for identifying therapeutic targets against osteoarthritis

Raphaëlle Lesage, Mauricio N. Ferrao Blanco, Roberto Narcisi, Tim Welting, Gerjo J. V. M. van Osch & Liesbet Geris
Additional file 3: Table S2. List of variables and mouse genes correspondence. All mathematical variables and the corresponding node in the network have names written in upper cases and do not reflect the official human or mouse nomenclatures. To relate those variables to actual genes more easily, we provide this table of correspondence. A related mouse gene name and NCBI ID is indicated for each variable. Nevertheless, this is not exhaustive since some variables represent...

Additional file 1 of Predictors of nursing home admission in the older population in Belgium: a longitudinal follow-up of health interview survey participants

Finaba Berete, Stefaan Demarest, Rana Charafeddine, Karin De Ridder, Johan Vanoverloop, Herman Van Oyen, Olivier Bruyère & Johan Van der Heyden
Additional file 1.

The use of psychedelics in the treatment of disorders of consciousness. An interview with Olivia Gosseries by Charlotte Martial.

Olivia Gosseries & Charlotte Martial
In this interview, we discuss the use of psychedelic drugs as a promising treatment in disorders of consciousness. Psilocybin, a classic psychedelic, is currently undergoing substantial clinical investigations in healthy volunteers, but also in clinical populations. Recently, experts in the field of psychedelics have addressed the attractive possibility to use such psychedelics on patients suffering from disorders of consciousness. Building on her empirical and theoretical research on disorders of consciousness, Olivia Gosseries gives us her...

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