Four new ionones and ionone glycosides (1–4) were isolated from the whole plant of Rehmannia piasezkii Maxim. Their planar structures as well as absolute configuration were confirmed via spectroscopic analysis, ECD calculation, and X-ray crystallography. Compounds 1–4 were tested for their cytotoxicity against five human tumor cell lines and ability to inhibit LPS-activated NO production in the BV2 cell line.

Additional file 2: Supplemental Table 1. Resources used for our coronavirus disease-related data collection.

Additional file 2: Supplemental Table 1. Resources used for our coronavirus disease-related data collection.

Supplemental figures

Additional file 1: Figure S1. Venn diagram of gene lists linked to type 2 diabetes by different types of evidence. Figure S2. Heterozygosity inferred by comparing the paternal and maternal scaffolded contigs, shown on the paternal scaffolds. Figure S3. Length distributions of structural variants. Figure S4. Functional classification of duplicated genes. Figure S5. Sequence alignment of Nile rat Gckr proteins to 113 mammalian orthologs. Figure S6. Missing Nile rat Hadh gene present in alternate haplotype...

Supplemental Material for Links of daily shared appraisal and collaboration to support, mood, and self-care in type 2 diabetes by Melissa Zajdel, Jeanean B Naqvi, Nynke MD Niezink and Vicki S Helgeson in Journal of Social and Personal Relationships

Supplemental figures

As part of an ongoing project on Rehmannia species, three new pyridine alkaloides (glutinosines A − C), and one new iridoid analogue (rehmaglutin E), were isolated from the leaves of Rehmannia glutinosa. The structures of the new compounds were established by extensive spectroscopic analysis and electronic circular dichroism calculations.

Fasting glucose variability (FGV) extensively promotes the onset and development of diabetic complications. This study aimed to evaluate the FGV in type 2 diabetes mellitus (T2DM) patients administered basal insulin using a needle-free insulin injector (NFII). This was a prospective randomized multicenter open-label crossover study. We randomly assigned 48 T2DM patients to receive basal insulin by NFII or conventional insulin pen (CIP) for 7–14 days and were then crossed over after washout. We conducted continuous...

Supplemental material for an investigation on the modelling of a finite porous liner for the sound propagation in a rectangular duct by Xiang Song, Jing jian Xu, Tian yue Yuan, Wen hao Sun, Dan Sui, He ye Xiao and Jie Zhou in Journal of Vibration and Control

Additional file 1: TableS1. Information on all metabolites. Table S2. Up- and downregulatedmetabolites. Table S3. RNA-sequencing profiles. Table S4. Number of up- anddownregulated differentially expressed genes. Table S5. The primers designedfor RT-qPCR.

Additional file 1: TableS1. Information on all metabolites. Table S2. Up- and downregulatedmetabolites. Table S3. RNA-sequencing profiles. Table S4. Number of up- anddownregulated differentially expressed genes. Table S5. The primers designedfor RT-qPCR.

As part of an ongoing project on Rehmannia species, three new pyridine alkaloides (glutinosines A − C), and one new iridoid analogue (rehmaglutin E), were isolated from the leaves of Rehmannia glutinosa. The structures of the new compounds were established by extensive spectroscopic analysis and electronic circular dichroism calculations.

Supplemental material for an investigation on the modelling of a finite porous liner for the sound propagation in a rectangular duct by Xiang Song, Jing jian Xu, Tian yue Yuan, Wen hao Sun, Dan Sui, He ye Xiao and Jie Zhou in Journal of Vibration and Control

Supplemental figures

Four new ionones and ionone glycosides (1–4) were isolated from the whole plant of Rehmannia piasezkii Maxim. Their planar structures as well as absolute configuration were confirmed via spectroscopic analysis, ECD calculation, and X-ray crystallography. Compounds 1–4 were tested for their cytotoxicity against five human tumor cell lines and ability to inhibit LPS-activated NO production in the BV2 cell line.

Additional file 1: Supplemental file 1. Visualization of the Evolution of CIDO.

Additional file 1: Supplemental file 1. Visualization of the Evolution of CIDO.

Additional file 3: Supplemental Table 2. CIDO statistics including terms imported from major reference ontologies.

Additional file 3: Supplemental Table 2. CIDO statistics including terms imported from major reference ontologies.

Fasting glucose variability (FGV) extensively promotes the onset and development of diabetic complications. This study aimed to evaluate the FGV in type 2 diabetes mellitus (T2DM) patients administered basal insulin using a needle-free insulin injector (NFII). This was a prospective randomized multicenter open-label crossover study. We randomly assigned 48 T2DM patients to receive basal insulin by NFII or conventional insulin pen (CIP) for 7–14 days and were then crossed over after washout. We conducted continuous...

Supplemental Material for Links of daily shared appraisal and collaboration to support, mood, and self-care in type 2 diabetes by Melissa Zajdel, Jeanean B Naqvi, Nynke MD Niezink and Vicki S Helgeson in Journal of Social and Personal Relationships

Additional file 1: Figure S1. Venn diagram of gene lists linked to type 2 diabetes by different types of evidence. Figure S2. Heterozygosity inferred by comparing the paternal and maternal scaffolded contigs, shown on the paternal scaffolds. Figure S3. Length distributions of structural variants. Figure S4. Functional classification of duplicated genes. Figure S5. Sequence alignment of Nile rat Gckr proteins to 113 mammalian orthologs. Figure S6. Missing Nile rat Hadh gene present in alternate haplotype...