Additional file 1: Supplemental file 1. Visualization of the Evolution of CIDO.

Additional file 1: Supplemental file 1. Visualization of the Evolution of CIDO.

Additional file 3: Supplemental Table 2. CIDO statistics including terms imported from major reference ontologies.

Additional file 3: Supplemental Table 2. CIDO statistics including terms imported from major reference ontologies.

The goal of the current study was to identify longitudinal changes in urinary metabolites following IR exposure and to determine potential alleviation of radiation toxicities by administration of recombinant APC formulations. Female adult WAG/RijCmcr rats were irradiated with 13.0 Gy leg-out partial body X-rays; longitudinally collected urine samples were subject to LC-MS based metabolomic profiling. Sub-cohorts of rats were treated with three variants of recombinant APC namely, rat wildtype (WT) APC, rat 3K3A mutant form...

Formula of PIMI calculation and simulation and experimental results for different sample status

Supplemental material, sj-docx-1-pie-10.1177_09544089221142205 for Control algorithm of weight on bit and rate of penetration based on drilling robot by Jianguo Zhao, Penghui Liang, Qingyou Liu, Shuo Han and Ying Zhang in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering

The massive application of agrochemicals and associated environmental residues greatly threaten human health. Cardiac dysfunction, as a major contributing factor to human mortality, is increasingly reported in health risk assessments to be associated with agrochemical exposure. In this mini-review, we summarize the cardiotoxicity of various agrochemicals including herbicides, insecticides, fungicides, and acaricides on zebrafish embryos/larvae and systematically discuss the role of cardiac development-related pathway disorders, imbalance in Ca2+ homeostasis, mitochondrial dysfunction, and general negative effects...

Additional file 1: Figure S1.The analysis of biological characteristics in human ADSCs.The ADSCs had successfully differentiated into chondrocytes(A), adipocytes(B), and osteoblasts(C). CD29, CD90, and CD105 were positive in human ADSCs(D). Figure S2.The ADSC-secreted EVs were incubated with M1 phenotype macrophages. Fluorescence images were used to evaluate localization of FITC-labeled NF-κB1 (p50) and Cy5-labeled NF-κB(p65). FQ,fluorescence quantitation; a.u., arbitrary unit. FigureS3. Internalizationof normal EVs and F4/80-EVs into M1 phenotype macrophages. Microscopic visualizationof internalization(left), and analysisof EVs...

Electrocatalytic CO2 reduction to fuel is one of the important ways to solve energy and environmental problems. In this work, the preparation of hollow Aux-Cu2O electrocatalyst and the performance of electrocatalytic CO2 reduction to ethanol were studied. Hollow Cu2O nanospheres were prepared by a soft template method, and Aux-Cu2O composites were prepared by galvanic replacement. The characterization results of XRD and XPS reveal that Cu+ is the main chemical state of Cu in the catalysts....

The antimicrobial activity and preservative effect of Ceylon spinach (Basella alba L.) seed protein extract on sturgeon fillets stored at 4°C were investigated in this study. The results showed that Ceylon spinach seed protein extract (CSSPE) had inhibitory effect on 33 microorganisms, including 1 fungus and 32 bacteria (25 gram-negative bacteria and 7 gram-positive bacteria). In addition, CSSPE inhibited bacterial growth (total viable counts, Pseudomonas, Aeromonas and psychrotrophs), suppressed ATP degradation and retained good-quality characteristic...

The massive application of agrochemicals and associated environmental residues greatly threaten human health. Cardiac dysfunction, as a major contributing factor to human mortality, is increasingly reported in health risk assessments to be associated with agrochemical exposure. In this mini-review, we summarize the cardiotoxicity of various agrochemicals including herbicides, insecticides, fungicides, and acaricides on zebrafish embryos/larvae and systematically discuss the role of cardiac development-related pathway disorders, imbalance in Ca2+ homeostasis, mitochondrial dysfunction, and general negative effects...

The goal of the current study was to identify longitudinal changes in urinary metabolites following IR exposure and to determine potential alleviation of radiation toxicities by administration of recombinant APC formulations. Female adult WAG/RijCmcr rats were irradiated with 13.0 Gy leg-out partial body X-rays; longitudinally collected urine samples were subject to LC-MS based metabolomic profiling. Sub-cohorts of rats were treated with three variants of recombinant APC namely, rat wildtype (WT) APC, rat 3K3A mutant form...

Supplemental material, sj-docx-1-tar-10.1177_17534666231155747 for Adenosine deaminase-based measurement in the differential diagnosis of pleural effusion: a multicenter retrospective study by Lijuan Gao, Wujun Wang, Ying Zhang, Xueru Hu, Jing An, Yang Li, Mei Chen and Yongchun Shen in Therapeutic Advances in Respiratory Disease

Breast cancer is one of the most common types of cancer in female patients with high morbidity and mortality. Multi-drug chemotherapy has significant advantages in the treatment of malignant tumors, especially in reducing drug toxicity, increasing drug sensitivity and reducing drug resistance. The objective of this research is to fabricate lipid nanoemulsions (LNs) for the co-delivery of PTX and docosahexaenoic acid (DHA) with folic acid (FA) decorating (PTX/DHA-FA-LNs), and investigate the anti-tumor activity of the...

Spoken sentences are continuous streams of sound, without reliable acoustic cues to word boundaries. We have previously proposed that language learners identify words via an implicit statistical learning mechanism that computes transitional probabilities between syllables. Neuroimaging studies in healthy young adults associate this learning with left inferior frontal gyrus, left arcuate fasciculus, and bilateral striatum. Here, we test the effects of healthy aging and left hemisphere (LH) injury on statistical learning. Following 10-minute exposure to...

Electrocatalytic CO2 reduction to fuel is one of the important ways to solve energy and environmental problems. In this work, the preparation of hollow Aux-Cu2O electrocatalyst and the performance of electrocatalytic CO2 reduction to ethanol were studied. Hollow Cu2O nanospheres were prepared by a soft template method, and Aux-Cu2O composites were prepared by galvanic replacement. The characterization results of XRD and XPS reveal that Cu+ is the main chemical state of Cu in the catalysts....

Supplemental material, sj-docx-1-cat-10.1177_10760296221139258 for Establishment of a Predictive Model for Poor Prognosis of Incomplete Revascularization in Patients with Coronary Heart Disease and Multivessel Disease by Huan Lian, Zhuoyan Zhao, Kelin Ma, Zhenjiang Ding, Lixian Sun and Ying Zhang in Clinical and Applied Thrombosis/Hemostasis

Arsenic has been identified as a carcinogen, although the molecular mechanism underlying itscarcinogenesis has not been fully elucidated. To date, only a few studies have attempted to confirm a direct link between oxidative stress and the Warburg effect . This study demonstrated that 0.2 μmol/L As3+ induced the Warburg effect to contribute to abnormal proliferation of L-02 cells, that was mediated by upregulation of hexokinase 2 (HK2), a key enzyme in glycolysis. Further study indicated...

Supplemental material, sj-pdf-1-smm-10.1177_09622802221129861 for A general method for calculating power for GEE analysis of complete and incomplete stepped wedge cluster randomized trials by Ying Zhang, John S Preisser, Elizabeth L Turner, Paul J Rathouz, Mark Toles and Fan Li in Statistical Methods in Medical Research

Supplemental material, sj-doc-1-jht-10.1177_10963480221137777 for When Service Customization in Tourism Backfires: Exploring the Value Restoration Mechanism to Prevent Value Codestruction by Lishan Xie, Xin Liu, Dongmei Li and Xinhua Guan in Journal of Hospitality & Tourism Research

Supplemental material, sj-docx-1-pie-10.1177_09544089221142205 for Control algorithm of weight on bit and rate of penetration based on drilling robot by Jianguo Zhao, Penghui Liang, Qingyou Liu, Shuo Han and Ying Zhang in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering

Formula of PIMI calculation and simulation and experimental results for different sample status

Preeclampsia (PE) is a disorder that occurs during the pregnancy and could affect the maternal and perinatal mortality as well as morbidity. The aim of our study is to investigate the associations between the hypertension susceptibility genes ITGA9, MOV10 and CACNB2 with PE in Chinese Han population. A case–control study including 178 PE patients and 202 healthy controls was conducted to assess the associations between three loci (ITGA9 rs155524, MOV10 rs2932538 and CACNB2 rs4373814) and...