Additional file 3. Flowchart of the invited and participating sample.

Additional file 2.

Additional file 1. Leisure Questionnaire

Additional file 3. Exploratory analysis including gender and cohort as predictors

Additional file 1: Supplement Figure S1. Bar graph for the different SPPB subtests.

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the...

Background: The four-dimensional (‘4-D’) model has been proposed as a theoretical framework to understand and delineate trauma-related dissociative experiences, categorizing symptoms into trauma-related altered states of consciousness (TRASC) and normal waking consciousness (NWC), which occur along four dimensions: time, thought, body and emotion. Objective: The main aim of the present study was to evaluate the validity of this model in patients with post-traumatic stress disorder (PTSD), with and without comorbid dissociative disorders. Method: The predictions...

The purpose of the present review is to report the incidence and characteristics of healthcare-associated urinary tract infections (HAUTIs) in urology with their microbiological and resistance patterns. Urinary tract infections are the main type of healthcare-associated infection in patients hospitalized in a urology ward. Patients admitted to urology departments report a high prevalence of urinary tract catheterization, up to 75% during the hospitalization period, and up to 20% had a urinary catheter before admission. An...

Additional file 2 Supplementary Material.

Additional file 2 Supplementary Material.

Objectives. Urinary albumin excretion is a risk marker for cardiovascular disease (CVD). Studies suggest that urinary orosomucoid may be a more sensitive marker of general endothelial dysfunction than albuminuria. The aim of this population-based cross-sectional study was to examine the associations between urinary orosomucoid to creatinine ratio (UOCR), urinary albumin to creatinine ratio (UACR) and subclinical CVD. Design. From the Tromsø Study (2007/2008), we included all men and women who had measurements of urinary orosomucoid...

Addiitional file 1: Figure S1. Comparison of transcript signal levels between os ilium–associated muscle and thigh muscle. Figure S2. Genes within the Diseases and Function category Vasculogenesis with increased (red) or reduced (green) expression end vs start of the training period in elderly as compared to young. Table S1. Common annotated genes changed in elderly in both Oslo and BSU cohorts at Q-value<0.1.

Additional file 1. Supplementary Figures 1–6.

Additional file 1: Section 1. Inclusion and Exclusion Criteria. Section 2. Supplementary Figures S1-S4. Fig. S1. Flow-chart of analyses population. Fig. S2. Margins plot of the estimated 30 days reduction at different intervals between first and second serum assessment. Fig. S3. Scatter plot of antibody levels and timing of blood sampling. Fig. S4. Levels of anti-RBD antibodies at first and second assessment across diagnoses. Section 3. Supplementary Tables S1-S5. Table S1. Predictors of anti-RBD level...

Meticulous inspection of the mucosa during colonoscopy, represents a lengthier withdrawal time, but has been shown to increase adenoma detection rate (ADR). We investigated if artificial intelligence-aided speed monitoring can improve suboptimal withdrawal time. We evaluated the implementation of a computer-aided speed monitoring device during colonoscopy at a large academic endoscopy center. After informed consent, patients ≥18 years undergoing colonoscopy between 5 March and 29 April 2021 were examined without the use of the speedometer,...

Cancers require telomere maintenance mechanisms for unlimited replicative potential. They achieve this through TERT activation or alternative telomere lengthening associated with ATRX or DAXX loss. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we dissect whole-genome sequencing data of over 2500 matched tumor-control samples from 36 different tumor types aggregated within the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium to characterize the genomic footprints of these mechanisms. While the...

Additional file 1. Dementia awareness questionnaire.

Additional file 2. Motivationto Change Lifestyle for Dementia Risk Reduction (MOHAD-10).

Additional file 3. Flowchart of the invited and participating sample.

The role of laparoscopy in the treatment of intrahepatic cholangiocarcinoma (ICC) remains unclear. This multicenter study examined the outcomes of laparoscopic liver resection for ICC. Patients with ICC who had undergone laparoscopic or open liver resection between 2012 and 2019 at four European expert centers were included in the study. Laparoscopic and open approaches were compared in terms of surgical and oncological outcomes. Propensity score matching was used for minimizing treatment selection bias and adjusting...

Additional file 1. SPIRIT 2013 Checklist: Recommended items to address in a clinical trial protocol and related documents*.

Additional file 2. Appendix II.

Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and evolutionary features. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we quantify hypoxia in 1188 tumours spanning...

Additional file 3. Exploratory analysis including gender and cohort as predictors

Supplemental Material for Marital Histories and Associations With Later-Life Dementia and Mild Cognitive Impairment Risk in the HUNT4 70+ Study in Norway by Vegard Skirbekk, Asta Håberg, Ekaterina Zotcheva, Bo Lars Engdahl, Steinar Krokstad, Hans-Peter Kohler, Astanand Jugessur, PhD, Bernt Bratsberg, Jordan Weiss, PhD, Catherine Bowen, Sarah Tom, PhD, Jennifer Harris, PhD, Yaakov Stern, PhD, Geir Selbæk, and Heine Strand, PhD in Journal of Aging and Health