46 Works

Telomere length and mitochondrial DNA copy number in bipolar disorder: A sibling study

Luana Spano, Bruno Etain, Jean-Louis Laplanche, Marion Leboyer, Sébastien Gard, Frank Bellivier & Cynthia Marie-Claire
An accelerated cellular ageing has been observed in bipolar disorder (BD) using biomarkers such as telomere length (TL) and mitochondrial DNA copy number (mtDNAcn). Several risk factors might drive premature ageing in individuals with BD, including a familial predisposition. This study compared TL and mtDNAcn between individuals with BD and their (un)-affected siblings, and explored factors that may explain proband-sibling differences. Sixty individuals with BD and seventy-four siblings (34 affected with BD or mood disorders...

Additional file 1 of Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

Sarah Aissi James, Christophe Guervilly, Mathieu Lesouhaitier, Alexandre Coppens, Clément Haddadi, Guillaume Lebreton, Jacky Nizard, Nicolas Brechot, Benjamin Assouline, Ouriel Saura, David Levy, Lucie Lefèvre, Pétra Barhoum, Juliette Chommeloux, Guillaume Hékimian, Charles-Edouard Luyt, Antoine Kimmoun, Alain Combes & Matthieu Schmidt
Additional file 1 Study flowchart. ECMO, extracorporeal membrane oxygenation; VV, veno venous; ARDS, acute respiratory distress syndrome.

Additional file 2 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 2 Supplementary Table 2. List of 57 common transcripts between those differentially expressed in our dataset (BD responders (R) versus non-responders (NR)) and other available transcriptomic studies in Pubmed. *: LCLs from Li-responders versus Li non-responders patients diagnosed with BD. #: Li-treated vs vehicle-treated LCLs from patients diagnosed with BD. Δ: before Li-treatment versus after Li-treatment in healthy controls. +: Li-treated vs vehicle-treated LCLs from Li-responders and Li non-responders patients diagnosed with BD....

Additional file 2 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 2 Supplementary Table 2. List of 57 common transcripts between those differentially expressed in our dataset (BD responders (R) versus non-responders (NR)) and other available transcriptomic studies in Pubmed. *: LCLs from Li-responders versus Li non-responders patients diagnosed with BD. #: Li-treated vs vehicle-treated LCLs from patients diagnosed with BD. Δ: before Li-treatment versus after Li-treatment in healthy controls. +: Li-treated vs vehicle-treated LCLs from Li-responders and Li non-responders patients diagnosed with BD....

Additional file 2 of Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors

Alice Blet, Joel B. McNeil, Julie Josse, Bernard Cholley, Raphaël Cinotti, Gad Cotter, Agnès Dauvergne, Beth Davison, Kévin Duarte, Jacques Duranteau, Marie-Céline Fournier, Etienne Gayat, Samir Jaber, Sigismond Lasocki, Thomas Merkling, Katell Peoc’h, Imke Mayer, Malha Sadoune, Pierre-François Laterre, Romain Sonneville, Lorraine Ware, Alexandre Mebazaa & Antoine Kimmoun
Additional file 2: Supplemental Text.

Additional file 1 of Accuracy of clinicians’ ability to predict the need for renal replacement therapy: a prospective multicenter study

Alexandre Sitbon, Michael Darmon, Guillaume Geri, Paul Jaubert, Pauline Lamouche-Wilquin, Clément Monet, Lucie Le Fèvre, Marie Baron, Marie-Line Harlay, Côme Bureau, Olivier Joannes-Boyau, Claire Dupuis, Damien Contou, Virginie Lemiale, Marie Simon, Christophe Vinsonneau, Clarisse Blayau, Frederic Jacobs & Lara Zafrani
Additional file 1: Figure S1. Physician prediction: Visual Likert Scale. Figure S2. PresagEER study timeline. Table S1. Delays between ICU admission, AKI diagnosis and RRT initiation. Table S2. RRT characteristics. Table S3. Characteristics and outcomes of AKI patients (n (%) or median (IQR)). Table S4. Multivariate analysis including variables associated with the risk of requiring RRT (without physician prediction).

Additional file 1 of Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults

Juliette Patrier, Khanh Villageois-Tran, Piotr Szychowiak, Stéphane Ruckly, Rémi Gschwind, Paul-Henri Wicky, Signara Gueye, Laurence Armand-Lefevre, Mehdi Marzouk, Romain Sonneville, Lila Bouadma, Marie Petitjean, Fariza Lamara, Etienne de Montmollin, Jean-Francois Timsit & Etienne Ruppé
Additional file 1: Table S1. Result of the initial 16S rDNA sequencing in rectal samples. Table S2. Per pathogen rectal and oropharyngeal culture positivity, time to first positivity and abundance at first positivity. Table S3. Adjusted impact of abundance of Enterococcus spp., S. aureus and Candida spp. in oropharynx and rectum on day 90 mortality. (one adjusted model for each). Table S4. Univariate analysis of day 90 mortality* comparing survivors versus descedents. Fig S1. Quantitative...

Additional file 1 of Clinical outcome of wild-type AmpC-producing Enterobacterales infection in critically ill patients treated with β-lactams: a prospective multicenter study

Roman Mounier, Ronan Le Guen, Paul-Louis Woerther, Mathieu Nacher, Clément Bonnefon, Nicolas Mongardon, Olivier Langeron, Eric Levesque, Séverine Couffin, Stéphanie Houcke, Michel Wolff, Ariane Roujansky, Caroline Schimpf, Armand Mekontso Dessap, Fabrice Cook, Keyvan Razazi & Hatem Kallel
Additional file 1. supplementary data on the methods and outcomes of the secondary objectives of the study.

Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?

Philippa C Matthews, Cori Campbell, Oana Săndulescu, Mojca Matičič, Simona Maria Ruta, Antonio Rivero-Juárez, Berend Joost van Welzen, Boun Kim Tan, Federico Garcia, George Sebastian Gherlan, Güle Çınar, İmran Hasanoğlu, Ivana Gmizić, Laura Ambra Nicolini, Lurdes Santos, Narina Sargsyants, Petar Velikov, Selma Habibović, Slim Fourati, Snježana Židovec-Lepej, Vanessa Herder, Susanne Dudman, Victor Daniel Miron, William Irving, Gülşen Özkaya Şahin … & ESCMID Study Group for Viral Hepatitis
During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged <6 years. Sporadic cases were then reported across Europe and worldwide, although in most countries incidence did not increase above the expected baseline. There were no consistent epidemiological links between cases,...

Additional file 4 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 4 Supplementary Table 4. List of 21 relevant functional networks identified by performing a network analysis in IPA on 335 differentially expressed mRNAs.

Additional file 1 of Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

Sarah Aissi James, Christophe Guervilly, Mathieu Lesouhaitier, Alexandre Coppens, Clément Haddadi, Guillaume Lebreton, Jacky Nizard, Nicolas Brechot, Benjamin Assouline, Ouriel Saura, David Levy, Lucie Lefèvre, Pétra Barhoum, Juliette Chommeloux, Guillaume Hékimian, Charles-Edouard Luyt, Antoine Kimmoun, Alain Combes & Matthieu Schmidt
Additional file 1 Study flowchart. ECMO, extracorporeal membrane oxygenation; VV, veno venous; ARDS, acute respiratory distress syndrome.

Additional file 2 of Delivery decision in pregnant women rescued by ECMO for severe ARDS: a retrospective multicenter cohort study

Sarah Aissi James, Christophe Guervilly, Mathieu Lesouhaitier, Alexandre Coppens, Clément Haddadi, Guillaume Lebreton, Jacky Nizard, Nicolas Brechot, Benjamin Assouline, Ouriel Saura, David Levy, Lucie Lefèvre, Pétra Barhoum, Juliette Chommeloux, Guillaume Hékimian, Charles-Edouard Luyt, Antoine Kimmoun, Alain Combes & Matthieu Schmidt
Additional file 2 Comparison of health-related quality of life assessed by mean SF-36 scores in ECMO-rescued ARDS survivors according to the timing of delivery. ECMO, extracorporeal membrane oxygenation; ARDS, acute respiratory distress syndrome; ICU, intensive care unit; IES, impact of event scales; PTSD, post-traumatic stress disorder.

Additional file 1 of Physiological response to prone positioning in intubated adults with COVID-19 acute respiratory distress syndrome: a retrospective study

Andrea Boffi, Maximilien Ravenel, Ermes Lupieri, Antoine Schneider, Lucas Liaudet, Michel Gonzalez, Jean-Daniel Chiche & Lise Piquilloud
Additional file 1: Table S1. Physiological, ventilatory and hemodynamic data for all the sessions considered together (n=191) and for the first (n=42), the second (n=37), the third (n=31), the fourth (n=18) and the fifth (n=14) proning sessions). Table S2. Variations in physiological and ventilatory parameters during the fourth (n=18), the fifth (n=14) proning sessions. Comparisons between the success and failure group.

Additional file 1 of Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review

Senta Jorinde Raasveld, Carolien Volleman, Alain Combes, Lars Mikael Broman, Fabio Silvio Taccone, Elma Peters, Sanne ten Berg, Charissa E. van den Brom, Holger Thiele, Roberto Lorusso, José P. S. Henriques & Alexander P. J. Vlaar
Additional file 1. Supplementary materials.

Acute severe hepatitis outbreak in children: A perfect storm. What do we know, and what questions remain?

Philippa C Matthews, Cori Campbell, Oana Săndulescu, Mojca Matičič, Simona Maria Ruta, Antonio Rivero-Juárez, Berend Joost van Welzen, Boun Kim Tan, Federico Garcia, George Sebastian Gherlan, Güle Çınar, İmran Hasanoğlu, Ivana Gmizić, Laura Ambra Nicolini, Lurdes Santos, Narina Sargsyants, Petar Velikov, Selma Habibović, Slim Fourati, Snježana Židovec-Lepej, Vanessa Herder, Susanne Dudman, Victor Daniel Miron, William Irving, Gülşen Özkaya Şahin … & ESCMID Study Group for Viral Hepatitis
During the first half of 2022, the World Health Organization reported an outbreak of acute severe hepatitis of unknown aetiology (AS-Hep-UA) in children, following initial alerts from the United Kingdom (UK) where a cluster of cases was first observed in previously well children aged <6 years. Sporadic cases were then reported across Europe and worldwide, although in most countries incidence did not increase above the expected baseline. There were no consistent epidemiological links between cases,...

Additional file 1 of Knowledge gaps and research priorities in adult veno-arterial extracorporeal membrane oxygenation: a scoping review

Senta Jorinde Raasveld, Carolien Volleman, Alain Combes, Lars Mikael Broman, Fabio Silvio Taccone, Elma Peters, Sanne ten Berg, Charissa E. van den Brom, Holger Thiele, Roberto Lorusso, José P. S. Henriques & Alexander P. J. Vlaar
Additional file 1. Supplementary materials.

Mid-trimester miscarriage and subsequent pregnancy outcomes: the role of cervical insufficiency in a cohort of 175 cases

Marion Joubert, Jeanne Sibiude, Stéphane Bounan & Laurent Mandelbrot
To evaluate the causes of MTM and their impact on subsequent pregnancies. A retrospective single-center cohort study of all pregnancies with a second-trimester pregnancy loss between 14 weeks and 21 weeks + 6 days gestation, excluding terminations of pregnancy (TOP) and in utero fetal deaths. Predefined criteria were used to allocate cases to one of 6 primary etiologic diagnoses: cervical insufficiency, chorioamnionitis, placental anomalies, fetal anomalies, iatrogenic causes, or abdominal trauma. Among 578 mid-trimester fetal...

Additional file 1 of Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults

Juliette Patrier, Khanh Villageois-Tran, Piotr Szychowiak, Stéphane Ruckly, Rémi Gschwind, Paul-Henri Wicky, Signara Gueye, Laurence Armand-Lefevre, Mehdi Marzouk, Romain Sonneville, Lila Bouadma, Marie Petitjean, Fariza Lamara, Etienne de Montmollin, Jean-Francois Timsit & Etienne Ruppé
Additional file 1: Table S1. Result of the initial 16S rDNA sequencing in rectal samples. Table S2. Per pathogen rectal and oropharyngeal culture positivity, time to first positivity and abundance at first positivity. Table S3. Adjusted impact of abundance of Enterococcus spp., S. aureus and Candida spp. in oropharynx and rectum on day 90 mortality. (one adjusted model for each). Table S4. Univariate analysis of day 90 mortality* comparing survivors versus descedents. Fig S1. Quantitative...

Additional file 1 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 1 Supplementary Table 1. List of 335 differentially expressed mRNAs identified in Li responders (R) versus non-responders (NR) with |FC| ≥ 1.2 and p-value ≤0.05.

Additional file 4 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 4 Supplementary Table 4. List of 21 relevant functional networks identified by performing a network analysis in IPA on 335 differentially expressed mRNAs.

Additional file 5 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 5 Supplementary Table 5. List of 77 differentially expressed mature miRNAs identified in Li responders (R) versus non-responders (NR) with |FC| ≥ 1.2 and p-value ≤0.05.

Additional file 6 of Transcriptomics and miRNomics data integration in lymphoblastoid cells highlights the key role of immune-related functions in lithium treatment response in Bipolar disorder

Nadia Cattane, Cindie Courtin, Elisa Mombelli, Carlo Maj, Cristina Mora, Bruno Etain, Frank Bellivier, Cynthia Marie-Claire & Annamaria Cattaneo
Additional file 6 Supplementary Table 6. List of 77 statistically significant pathways targeted by differentially modulated miRNAs identified using Diana Tool software (miRPath v.3). MiRNAs and their targeted mRNAs are also reported.

Additional file 1 of Growth pattern in children with X-linked hypophosphatemia treated with burosumab and growth hormone

Diana-Alexandra Ertl, Justin Le Lorier, Andreas Gleiss, Séverine Trabado, Candace Bensignor, Christelle Audrain, Volha Zhukouskaya, Régis Coutant, Jugurtha Berkenou, Anya Rothenbuhler, Gabriele Haeusler & Agnès Linglart
Additional file 1: Table S1. Demographic, clinical and biochemical characteristics for group 1 (burosumab only). Median, minimum and maximum for demographic and biochemical parameters.

Additional file 2 of Growth pattern in children with X-linked hypophosphatemia treated with burosumab and growth hormone

Diana-Alexandra Ertl, Justin Le Lorier, Andreas Gleiss, Séverine Trabado, Candace Bensignor, Christelle Audrain, Volha Zhukouskaya, Régis Coutant, Jugurtha Berkenou, Anya Rothenbuhler, Gabriele Haeusler & Agnès Linglart
Additional file 2: Table S2 Demographic, clinical and biochemical characteristics for group 2 (burosumab and rhGH). Median, minimum and maximum for demographic and biochemical parameters

Additional file 1 of Accuracy of clinicians’ ability to predict the need for renal replacement therapy: a prospective multicenter study

Alexandre Sitbon, Michael Darmon, Guillaume Geri, Paul Jaubert, Pauline Lamouche-Wilquin, Clément Monet, Lucie Le Fèvre, Marie Baron, Marie-Line Harlay, Côme Bureau, Olivier Joannes-Boyau, Claire Dupuis, Damien Contou, Virginie Lemiale, Marie Simon, Christophe Vinsonneau, Clarisse Blayau, Frederic Jacobs & Lara Zafrani
Additional file 1: Figure S1. Physician prediction: Visual Likert Scale. Figure S2. PresagEER study timeline. Table S1. Delays between ICU admission, AKI diagnosis and RRT initiation. Table S2. RRT characteristics. Table S3. Characteristics and outcomes of AKI patients (n (%) or median (IQR)). Table S4. Multivariate analysis including variables associated with the risk of requiring RRT (without physician prediction).

Registration Year

  • 2022
    44
  • 2021
    2

Resource Types

  • Text
    46

Affiliations

  • Assistance Publique - Hôpitaux de Paris
    46
  • University of Paris
    33
  • Inserm
    26
  • Fondation FondaMental
    11
  • University Hospital Cologne
    11
  • Hôpital Bichat-Claude-Bernard
    10
  • University of Paris-Saclay
    10
  • University of Milan
    9
  • Sorbonne University
    9
  • Centro San Giovanni di Dio Fatebenefratelli
    8