2 Works

Polydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy

Yi Wei, Li Gao, Lu Wang, Lin Shi, Erdong Wei, Baotong Zhou, Li Zhou & Bo Ge
Journal Contribution published via Taylor & Francis
We reported a simple polydopamine (PDA)-based surface modification method to prepare novel targeted doxorubicin-loaded mesoporous silica nanoparticles and peptide CSNRDARRC conjugation (DOX-loaded MSNs@PDA-PEP) for enhancing the therapeutic effects on bladder cancer. Drug-loaded NPs were characterized in terms of size, size distribution, zeta potential, transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET) surface area and drug loading content. In vitro drug release indicated that DOX-loaded MSNs@PDA and MSNs@PDA-PEP had similar release kinetic profiles of DOX. The PDA coating...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.4880774 Cite

Polydopamine and peptide decorated doxorubicin-loaded mesoporous silica nanoparticles as a targeted drug delivery system for bladder cancer therapy

Yi Wei, Li Gao, Lu Wang, Lin Shi, Erdong Wei, Baotong Zhou, Li Zhou & Bo Ge
Journal Contribution published via Taylor & Francis
We reported a simple polydopamine (PDA)-based surface modification method to prepare novel targeted doxorubicin-loaded mesoporous silica nanoparticles and peptide CSNRDARRC conjugation (DOX-loaded MSNs@PDA-PEP) for enhancing the therapeutic effects on bladder cancer. Drug-loaded NPs were characterized in terms of size, size distribution, zeta potential, transmission electron microscopy (TEM), Brunauer–Emmett–Teller (BET) surface area and drug loading content. In vitro drug release indicated that DOX-loaded MSNs@PDA and MSNs@PDA-PEP had similar release kinetic profiles of DOX. The PDA coating...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.4880774.v1 Cite

Registration Year

  • 2017
    2

Resource Types

  • Text
    2

Affiliations

  • Yunnan University
    2
  • Second Affiliated Hospital of Guangzhou Medical University
    2
  • Institute of Hydrobiology
    2
  • University of Greenwich
    2
  • University of Newcastle Australia
    2
  • University of Michigan–Ann Arbor
    2
  • Peking University Cancer Hospital
    2
  • Huazhong University of Science and Technology
    2
  • Minjiang University
    2
  • University of Rochester Medical Center
    2

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