The antimicrobial activity and preservative effect of Ceylon spinach (Basella alba L.) seed protein extract on sturgeon fillets stored at 4°C were investigated in this study. The results showed that Ceylon spinach seed protein extract (CSSPE) had inhibitory effect on 33 microorganisms, including 1 fungus and 32 bacteria (25 gram-negative bacteria and 7 gram-positive bacteria). In addition, CSSPE inhibited bacterial growth (total viable counts, Pseudomonas, Aeromonas and psychrotrophs), suppressed ATP degradation and retained good-quality characteristic...

Although cardiac disorder-related adverse events (AEs) have been reported in patients treated with aryl hydrocarbon receptor (AHR) agonists, their safety profiles remain unknown. Here, we identified significant cardiac disorders associated with AHR agonists and further evaluated their relevance. Database queries were performed using OpenVigil 2.1 and AEs voluntarily submitted to Food and Drug Administration Adverse Event Reporting System (FAERS) between 2004 and 2020 were included. This study based on the Medical Dictionary for Regulatory Activities...

The microstructure of fibrous paper plays an important role in its property investigation. In this study, an approach is proposed to extrapolate a 2D image into a virtual 3D microstructure. Five types of handsheets made of different pulps were prepared. Then, a hybrid function of two-point correlation and lineal-path function (S2&L2) and co-occurrence correlation functions (CCFs) was used in the simulated annealing reconstruction method. Thus, microstructures of two-phase fiber-pore handsheets were reconstructed using 2D scanning...

Research Data for A case series of constrictive pericarditis and suggested echocardiographic diagnostic criteria by Junfang Li, Rong Li, Guangting Cheng, Changhong Lu, Weigang Liu, Dongmei Sun, Xue Li and Zhibin Wang in Journal of International Medical Research

Phosphatidylinositol 3,4,5-triphosphate (PIP3) plays a key role in neuronal polarization and axon formation. PIP3-containing vesicles are transported to axon tips by the kinesin KIF13B via an adaptor protein, centaurin α1 (CENTA1). KIF13B interacts with CENTA1 through its forkhead-associated (FHA) domain. We solved the crystal structures of CENTA1 in ligand-free, KIF13B-FHA domain-bound, and PIP3 head group (IP4)-bound conformations, and the CENTA1/KIF13B-FHA/IP4 ternary complex. The first pleckstrin homology (PH) domain of CENTA1 specifically binds to PIP3, while...

Additional File 2: Supplementary Figure

Coxsackievirus A10 (CV-A10) has become one of the major pathogens of hand, foot and mouth disease (HFMD), and studies on the vaccine and animal model of CV-A10 are still far from complete. Our study used a mouse-adapted CV-A10 strain, which was lethal for 14-day-old mice, to develop an infected mouse model. Then this model was employed to establish an actively immunized-challenged mouse model to evaluate the efficacy of a formaldehyde-inactivated CV-A10 vaccine, which was prepared...

Supplementary Material 3: Table S1: The specific search strategies

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Additional file 1: Table S1. Information of PEDV strains obtained in this study. The information including strain name, collection date, collection region, S gene length, virus isolation and accession number.

Additional file 5: Fig. S1. MβCD plus anti-GD2 treatment inhibits tumor growth in vivo. A, Schematic of MβCD and anti-GD2 treatments. B, Representative images of xenograft 9464D tumors with different treatments. C, The tumors were removed for weight analysis 21 days after the beginning of treatments. D, Tumor growth curves of subcutaneous 9464D cells with different treatments. Fig. S2. Monitoring of mouse weight during the experiment.

Additional file 1: Extract parameter details and the results of each step of feature extraction.

Additional file 2: Table S2. Immunohistochemical reaction protocols.

Additional file 3: Table S3. Antigen retrieval protocol.

Additional file 3: Table S3. Antigen retrieval protocol.

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Additional file 2. National Health Commission of China for Guiding Principle of Clinical Use of Antibiotics.

Supplemental material, sj-docx-1-cre-10.1177_02692155221135729 for Effect of respiratory muscle training in patients with chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials by Fan Zhang, Hui Wang, Yan Bai, Liuyan Huang and Huachun Zhang in Clinical Rehabilitation

Supplemental material, sj-docx-4-cre-10.1177_02692155221135729 for Effect of respiratory muscle training in patients with chronic kidney disease: A systematic review and meta-analysis of randomized controlled trials by Fan Zhang, Hui Wang, Yan Bai, Liuyan Huang and Huachun Zhang in Clinical Rehabilitation

Supplemental material, sj-pdf-2-imr-10.1177_03000605221139667 for Osteoperiosteal decortication and bone grafting combined with wave plating for femoral shaft aseptic atrophic nonunion after intramedullary nailing by Yao Lu, Liang Sun, Qian Wang, Cheng Ren, Yibo Xu, Haobo Ye, Ming Li, Hanzhong Xue, Qiang Huang, Zhong Li, Kun Zhang and Teng Ma in Journal of International Medical Research

Additional file 1: Figure S1. A. CS-1 loading capacity and encapsulation efficiency of CPCCM NPs. B. Ce6 loading capacity and encapsulation efficiency of CPCCM NPs. Figure S2. Cell viability assay. A. Viability of 4T1 cells treated with CS-1. B. Viability of MDA-MB-231 cells treated with CS-1. The concentrations of CS-1 are 0, 1, 2.5, 5, 10, 15, and 20 μM, respectively. Figure S3. Viability of MDA-MB-231 cells treated with CS-1, Ce6, CPCC, and CPCCM with/without...

Additional file 5. Fig. S32: The host assignment of plant-associated viruses by using BLASTx searching the contigs assembled from the NGS data of each plant species (those containing possible non-plant-infecting virus) against the total mitochondrial proteome database that were downloaded from GenBank.

Supplement 1

Supplemental material, sj-pdf-2-ict-10.1177_15347354221137285 for Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer by Samantha K. Greaney, Neha Amin, Bethany C. Prudner, Maggie Compernolle, Linda J. Sandell, Susan C. Tebb, Katherine N. Weilbaecher, Peri Abeln, Jingqin Luo, Yu Tao, Angela C. Hirbe and Lindsay L. Peterson in Integrative Cancer Therapies

The integration of nanofiltration with catalysis enables high-efficient removal of micropollutants due to its remarkable high selectivity and superior degradation efficacy. Meanwhile, the catalysis-assisted nanofiltration can largely alleviate the issues of inferior low-molecular-weight micropollutants selectivity, membrane fouling and tradeoff limitation. Two different technical routes, catalytic coupled nanofiltration system and catalytic nanofiltration membrane, have been developed based on nanofiltration module and material design for micropollutants separation enhancement. In this review, we first summarize the underlying governing...