Supplemental material, sj-docx-1-chl-10.1177_17475198221116827 for The design and synthesis of benzylpiperazine-based edaravone derivatives and their neuroprotective activities by Mengjie Gao, Shuangyan Ma, Tong Xu, Nan Jiang, Yi Xu, Yan Zhong and Bin Wu in Journal of Chemical Research

Supplemental material, sj-pdf-1-smm-10.1177_09622802221129861 for A general method for calculating power for GEE analysis of complete and incomplete stepped wedge cluster randomized trials by Ying Zhang, John S Preisser, Elizabeth L Turner, Paul J Rathouz, Mark Toles and Fan Li in Statistical Methods in Medical Research

Additional file 3: Supplement Fig. 3. Western blot analysis between recombinant antigen and purified polyclonal antibody. The blot membrane was cut prior to hybridization with polyclonal antibody A: the blot membrane was in the Brightfield; B: the blot membrane was imaged by the Bio-Rad ChemiDoc XRS+.

Additional file 4: Supplementary Table 1. A total 36 samples was detected by the commercial ELISA Kit and the OD values at 450 nm was presented in this table.

Additional file 1: Demographic, breast cancer epidemiological and screening factors of the female populations in China.

Additional file 3: Age-specific incidence, mortality and survival rates of breast cancer.

Additional file 2.

Additional file 1: Figure S1. (A) Representative images of dissected tumors across the different treatment groups. (B-C) PCNA protein expression levels were selected as indices of tumor tissue proliferation for immunohistochemical detection and analysis. (D-E) TUNEL experiment of tumor tissues in different treatment groups. Figure S2. Hematoxylin and eosin staining tests (Figure S2A) and serum biochemical indices, including albumin, alanine aminotransferase, creatinine, and urea levels,(Figure S2B-E) showed that there was no significant histological evidence of...

3D printing technology has significant advantages in the processing field of vascular tissue engineering. We have developed KCMA/SA hydrogels based on methacrylated carrageenan (KCMA) and sodium alginate (SA), which have low viscosity and shear thinning properties and can be used for 3D printing. The physicochemical double cross-linked network structure leads to good mechanical properties. The composite hydrogels maintain the liquid crystallinity of KC, which causes the HUVECs to align. The KCMA/SA gel filaments printed by...

Pilots’ operation behavior in flight is associated with their mental state variables such as workload, situation awareness, stress, etc. The objective of this study was to investigate the dynamic process of mental workload for pilots who perform a risky flight task in simulated scenarios. Two empirical experiments were conducted to address this issue. In experiment one, 19 trainee pilots divided into high-risk and low-risk groups performed a target-search task in a low-altitude visual flight. The...

The detection of fungi in the human respiratory tract may represent contamination, colonization or a respiratory infection. To develop effective management strategies, a more accurate and comprehensive understanding of the lung fungal microbiome is required. Therefore, the objective of the present study was to define the “mycobiome” of mechanically ventilated patients admitted to an intensive care unit (ICU) using broncho-alveolar aspirate (“sputum”) samples and correlate this with clinical parameters and the bacterial microbiota. To this...

In the current work, the RBE of a 212Pb-conjugated anti-HER2/neu antibody construct has been evaluated, in vitro, by colony formation assay. The RBE was estimated by comparing two absorbed dose-survival curves: the first obtained from the conjugated 212Pb experiments (test radiation), the second obtained by parallel experiments of single bolus irradiation of external beam (reference radiation). Mammary carcinoma NT2.5 cells were treated with (0–2.47) kBq/ml of radiolabeled antibody. Nonspecific binding was assessed with addition of...

Resource conservation, sustainability, quality, and cost control have been considered significant issues for the construction sector worldwide. Green Lean Six Sigma not only improves quality, process flow, resource conservation, and environmental performance but also minimizes cost, waste, and lead time. The construction sector in Pakistan is struggling to adopt sustainable and quality-oriented practices. In this context, this paper aims to identify Green Lean Six Sigma enablers from the perspective of Pakistan’s construction industry. Interpretive Structural...

A high-dimensional neural network interatomic potential was developed and used in molecular dynamics simulations of condensed phase Ni and Ni systems with liquid–solid phase coexistence. The reference data set was generated by sampling the potential energy surface over a broad temperature-pressure domain using ab initio MD simulations to train a unified potential. Excellent agreement was achieved between bulk face-centred cubic nickel thermal expansion simulations and relevant experimental data. The same potential also yields accurate structures...

Additional file 2. Fig. S1: Pictures of plant strains or leaves collected in the present study.

Additional file 1: Table S1. Serum concentration of CTRP9 and APN in patients of different infarct stages.

Additional file 1. Table S-1. Comparison of different architectures of deep neural networks. Table S-2. Results of deep learning features.

Additional file 1: Supplemental Table 1. Interaction and stratified analysis results for the association between marijuana use and GrimAge acceleration at examination years 15 and 20 by tobacco smoking status. Supplemental Table 2. Interaction and stratified analysis results for the association between marijuana use and GrimAge acceleration at examination years 15 and 20 by race. Supplemental Table 3. Interaction and stratified analysis results for the association between marijuana use and GrimAge acceleration at examination years...

Additional file 1. Figure S1: Mendelian error rate of all families. Figure S2: The number of de novo mutations in probands and siblings followed Poisson distribution. Figure S3: Gene (protein synthesis) expression in different brain regions at various periods. Figure S4: Gene (energy) expression in different brain regions at various periods. Figure S5: Gene (pressure) expression in different brain regions at various periods. Figure S6: Gene (amino acid) expression in different brain regions at various...

Additional file 1.

Additional file 1: Table S1. Baseline demographics of MSA. Table S2. The comparison of frequency of each NMSS domain at baseline and 1- and 2-year follow-up.

High-resolution figures for Fig. 4 (a)-(d), Fig. 5 (b)(e)(h), Fig.11 (a) (b) and Fig.14 (a)(b)(d)(e), respectively.

Supplemental material, sj-docx-1-ict-10.1177_15347354221137285 for Yoga Therapy During Chemotherapy for Early-Stage and Locally Advanced Breast Cancer by Samantha K. Greaney, Neha Amin, Bethany C. Prudner, Maggie Compernolle, Linda J. Sandell, Susan C. Tebb, Katherine N. Weilbaecher, Peri Abeln, Jingqin Luo, Yu Tao, Angela C. Hirbe and Lindsay L. Peterson in Integrative Cancer Therapies

Additional file 3. Informed consent in Chinese.

Additional file 4. Informed consent in English.