Additional file 1.

Additional file 12: Supplementary Figure 6. Rectal propionate administration attenuated VDN-induced microbial dysbiosis in rats. (a) Relative abundance of intestinal microbiota constituents at the genus level. (b-j) Relative abundance of identified differentially abundant bacterial groups at different taxonomic levels. Data are presented as the mean ± standard deviation (SD). Statistical significance was determined using one-way ANOVA or the Kruskal–Wallis test (Tukey or Dunnett post hoc test). NS for P > 0.05, *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.

Additional file 13: Supplementary Figure 7. Alleviation of intestinal mucosal barrier impairment in rats by rectal propionate administration. (a) Typical haematoxylin-eosin (HE) staining, periodic acid-Schiff (PAS) staining and MUC2 immunohistochemical staining for intestinal tissues (original magnification ×200). (b), (c), (d) and (e) Parameters of crypt depth, intestinal wall thickness, goblet cell count and MUC2 expression levels, respectively. (f) and (g) Plasma D-lactate and diamine oxidase contents, respectively. (h) Spearman’s correlation analysis of the relationship of...

Additional file 17: Supplementary Figure 10. Attenuation of VDN-induced microbial dysbiosis in rats by Akkermansia. (a) Venn diagram showing gut microbiota constituents coenriched by oral and rectal propionate administration and propionate-modulated intestinal microbiota transplantation. (b) Receiver operating characteristic (ROC) curves showing the ability of Muribaculaceae and Akkermansia abundance to predict vascular calcification. (c) Relative abundance of intestinal microbiota constituents at the genus level. (d) Plasma LPS levels. (e-r) Relative abundance of identified differentially abundant bacterial...

Additional file 1:Figure S1. Comparison of the expression levels of cell-cycle related genes in young panicles of R498 and wg3 by qRT–PCR. Figure S2. Identification of the causal gene responsible for wide grains of the wg3 mutant using the MutMap strategy. Figure S3. Alignment of the amino acid sequences of WG3 from WT and mutants. Figure S4. Expression pattern analysis of WG3. Figure S5. A dlt mutant was identified from the R498 mutant library using...

Additional file 2: Materials and Methods.

Supplemental material, sj-docx-1-aut-10.1177_13623613221132743 for Socioeconomic factors and autism among 16- to 30-month-old children: Evidence from a national survey of China by Muqing Cao, Li Li, Hein Raat, Amy Van Grieken, Xin Wang, Lizi Lin, Qiang Chen and Jin Jing in Autism

Supplemental material, sj-pdf-1-imr-10.1177_03000605221121954 for The ultrastructural and morphological characteristics of the anterior cruciate ligament of the pig: a study using 7.0-Tesla diffusion tensor imaging by Tian You, Fujia Jiao, Wentao Zhang, Qingjun Yang, Wenqian Lu and Yong Luo in Journal of International Medical Research

Additional file 9.

Additional file 1: Fig. S1. Quality control of single-cell RNA sequencing data. Fig. S2. Identification of venous endothelial cell as another EC subtypes significantly changed under MCAO condition. Fig. S3. The differentiation path and stemness of Healing-state endothelial cell. Fig. S4. Demonstration of 3D tomography from different planes. Fig. S5. Cellular communication analysis indicating the key roles of endothelial cells in the brain microenvironment. Fig. S6. Aberrantly changed cell communication under MCAO condition. (DOCX)

Additional file 3: Supplemental file 3. Begg’s test and Egger's test for each outcome.

Additional file1: Fig. S1. OUM1 knockdown impairs UM cell metastasis and proliferation. Fig. S2. GO and pathway function analysis. Fig. S3. Bioinformatics analysis of OUM1 targets. Fig. S4. PTPRZ1 might be a target of OUM1. Fig. S5. Synergistic effect of SOV and OUM1 interference on apoptosis. Fig. S6. In vivo toxicity evaluation. Table S1. Downregulated and Upregulated gene. Table S2. Primers and siRNA used in this study. Table S3. Primers used in RNA-ChIP assay. Details...

Supplemental material, sj-docx-1-npx-10.1177_1934578X221136674 for Fisetin Ameliorates Levodopa-Induced Dyskinesia in Experimental Model Parkinson's Disease: Role of Mitochondrial Activities and Monoamines Turnover by Wenhui Cao, Shaodong Liang, Yindong Yang, Chuanzhen Zhu, Li Sun and Liming Zhang in Natural Product Communications

Additional file 9: Table S2. The Gating Scheme of Isolations of Cells from Whole Blood or PBMCs.

Additional file 9: Table S2. The Gating Scheme of Isolations of Cells from Whole Blood or PBMCs.

High-resolution figures for Fig. 4 (a)-(d), Fig. 5 (b)(e)(h), Fig.11 (a) (b) and Fig.14 (a)(b)(d)(e), respectively.

Supplemental material, sj-pdf-2-wso-10.1177_17474930221140792 for Human blood metabolites and lacunar stroke: A Mendelian randomization study by Meng-Nan Guo, Xiao-Yan Hao, Jie Tian, Yun-Chao Wang, Jia-Di Li, Yu Fan, Jing-Jing Shi, Dong-Rui Ma, Shuang-Jie Li, Chun-Yan Zuo, Yuan-Yuan Liang, Meng-Jie Li, Si Shen, Fen Liu, Da-Bao Yao, Yu-Ming Xu and Chang-He Shi in International Journal of Stroke

Supplemental Material for Modelling Chinese Youth Support for Military Intervention in the Diaoyu/Senkaku Islands: Beyond Nationalism and Militarism by Graeme Davies, Kingsley Edney, and Bo Wang in Journal of Conflict Resolution

Additional file 2. Supplementary files NO.2 Search strategy.

Additional file 1: Table S1. Primers used for qRT-PCR.

Two new complexes, [Cu(dmp)(2-bdppmapy)](CF3SO3)·CH2Cl2 (1) and [Cu(imidazo[4,5-f])(2-bdppmapy)](SCN) (2) (2-bdppmapy = N,N-bis[(diphenylphosphino)methyl]-2-pyridinamine, dmp = 2,9-dimethyl-(1,10)phenanthroline and imidazo[4,5-f] = 1H-imidazo[4,5f][1,10]phenanthroline), have been synthesized in mixed solvents of CH3OH and CH2Cl2 (1:1, V/V). On the basis of studying the structure and photophysical properties of the Cu(I) complexes, the effects of different N ligands and counter anions on the luminescence properties of the Cu(I) complexes were characterized by single-crystal X-ray diffraction, fluorescence spectra and terahertz time-domain spectroscopy (THz-TDS). The...

Supplemental material, sj-docx-1-wmr-10.1177_0734242X221136467 for Material flow analysis and characteristics of multiple-source organic solid wastes from a perspective of ecological network analysis: A case study in Hefei, China by Yulin Zhang, Chuncai Zhou, Jiao Du, Min Wang, Wentao Wu and Guijian Liu in Waste Management & Research

Additional file 4: Fig. S3 Effect of adipocyte CM on the expression level of Snail, Slug, ZEB1 and ZEB2 in EOC cells. A SKOV3 cells were serum starved overnight and cultured in SFM or adipocyte CM for 48 h. Expression levels of Snail, Slug, ZEB1 and ZEB2 were determined by Western blot and normalized to GAPDH. Densitometric analyses were shown on the right. Experiments have been carried out with adipocytes from 2 to 3 independent...

Additional file 5: Fig. S4 Inhibition of Twist1 by siRNA suppressed adipocyte-induced metastasis of EOC cells. A SKOV3 and HEY cells were transfected with negative control siRNA (si-Ctrl) or Twist1 siRNA (si-Twist1). 24 h after transfection, mRNA level of Twist1 was determined by qRT-PCR and normalized to GAPDH. Data are mean ± SD (n = 3). **P < 0.01; two-tailed Student’s t-test. B 48 h after transfection, protein level of Twist1 was determined by Western...

Additional file 6: Fig. S5 Inhibition of SphK1 suppressed omental metastasis of EOC in vivo. A Expression of SphK1 in stable transfected SKOV3 cells tested by qRT-PCR and Western blot. GAPDH was used as a loading control. Data are mean ± SD (n = 3). *P < 0.05 versus Blank; ns, no significance versus Blank; two-tailed Student’s t-test. B Representative images of disseminated tumors in intraperitoneal EOC xenograft mouse models injected with Ctrl shRNA (sh-Ctrl)...