839 Works

Evaluation of an enclosed air-lift photobioreactor (ALPBR) for biomass and lipid biosynthesis of microalgal cells grown under fluid-induced shear stress

Ning Ding, Chao Li, Tao Wang, Meijin Guo, Ali Mohsin & Siliang Zhang
An enclosed air-lift photobioreactor (ALPBR) is considered an efficient lab-scale bioreactor for microalgae cell growth and lipid biosynthesis. However, fluid-induced shear stress and mixing are two main factors that affect physiological metabolism in microalgal cell cultures. Herein, a 50-L ALPBR after being designed and manufactured was evaluated for microalgal suspension culture. Moreover, computational fluid dynamics (CFD) simulation was used to characterize the hydrodynamics of ALPBR. Specifically, two model microalgae species Chlorella vulgaris and Chlorella protothecoides...

Comprehensive analysis of lncRNA expression profiles in cytopathic biotype BVDV-infected MDBK cells provides an insight into biological contexts of host–BVDV interactions

Xuwen Gao, Chao Niu, Zhuo Wang, Shuo Jia, Meijing Han, Yingying Ma, Xueting Guan, Li Wang, Xinyuan Qiao & Yigang Xu
Bovine viral diarrhea virus (BVDV) is the causative agent of bovine viral diarrhea-mucosal disease, which significantly affects the production performance of cattle, causing serious economic losses to the cattle industries worldwide. Up to now, some mechanisms involved in host–BVDV interaction are still not fully understood. The discovery of long non-coding RNAs (lncRNAs) has provided a new perspective on gene regulation in diverse biological contexts, particularly in viral infection and host immune responses. However, little is...

Heterologous expression and enzymatic identification of two novel soluble pyridine nucleotide transhydrogenases from Acidobacteria bacterium KBS 146 and Nocardia jiangxiensis

Zhengyu Cao, Rui Meng, Peng Wang & Guoping Zhu
Soluble pyridine nucleotide transhydrogenase (STH), catalyzes a reversible hydrogen transfer between NADH and NADPH, is widely utilized in cofactor engineering. In the present study, we expanded the distribution range of STH to more unreported bacteria. Meanwhile, STH was mainly found in α, γ, δ-proteobacteria, acidobacteria, actinobacteria and planctomycetes. The enzymological properties of two novel STHs from Acidobacteria bacterium KBS 146 (AbSTH) and Nocardia jiangxiensis (NjSTH) were characterized. The optimum temperature and pH of AbSTH and...

Supplemental Material, sj-pdf-1-ssc-10.1177_08944393211042575 - Strategic Framing Matters But Varies: A Structural Topic Modeling Approach to Analyzing China’s Foreign Propaganda About the 2019 Hong Kong Protests on Twitter

Maggie Mengqing Zhang, Xiao Wang & Yang Hu
Supplemental Material, sj-pdf-1-ssc-10.1177_08944393211042575 for Strategic Framing Matters But Varies: A Structural Topic Modeling Approach to Analyzing China’s Foreign Propaganda About the 2019 Hong Kong Protests on Twitter by Maggie Mengqing Zhang, Xiao Wang and Yang Hu in Social Science Computer Review

A transcriptomic analysis of neuropathic pain in the anterior cingulate cortex after nerve injury

Yu Zhang, Shiwei Jiang, Fei Liao, Zhifeng Huang, Xin Yang, Yu Zou, Xin He, Qulian Guo & Changsheng Huang
The anterior cingulate cortex (ACC) is a core brain region processing pain emotion. In this study, we performed RNA sequencing analysis to reveal transcriptomic profiles of the ACC in a rat chronic constriction injury (CCI) model. A total of 1628 differentially expressed genes (DEGs) were identified by comparing sham-operated rats with rats of 12 hours, 1, 3, 7, and 14 days after surgery, respectively. Although these inflammatory-related DEGs were generally increased after CCI, different kinetics...

Molecular evidence to the day length in regulating the short shoot phenomenon during summer in roses (Rosa sp.)

Li Wang, Wan Jiang, Wuhua Zhang, Weitong Chen, Yu Mo, Tong Zhou, Jinzhu Zhang & Daidi Che
The short shoot phenomenon is an important phenotype underlying the economic value of roses – node number can directly affect shoot length. To elucidate the molecular mechanism of how day length affects shoot length, the effect of 8, 10, and 12 h day lengths on node number were studied. The number of nodes between the 8 and 12 h treatment groups significantly differed. Node development in the 12 h treatment group occurred significantly earlier than...

Synthesis, herbicidal activity study, and molecular docking of novel acylthiourea derivatives

Binbin Jiang, Yunlong Chai, Xu He, Yan Wang, Bo Chen, Yang Li & Ranhong Li
A series of new acylthiourea derivatives were synthesized and characterized. The results of preliminary herbicidal activity tests showed that most compounds had good herbicidal activity against Digitaria adscendens and Amaranthus retroflexus, especially for compounds 4b (N-(2-chloro-4-methylsulfonylbenzoyl)-N’-(2-chlorophenyl) thiourea) and 4f (N-(2-chloro-4-methylsulfonylbenzoyl)-N’-(2,3-dichlorophenyl) thiourea). In vivo acetylhydroxylate synthase (AHAS) enzyme activity inhibition tests showed that all compounds had inhibitory activities against the enzyme at a concentration of 100 mg·L−1, with the highest inhibition rate up to 37.05% (compound...

E74 Like ETS Transcription Factor 3 is a Negative Regulator of Pathogenic Lamina Propria T Helper 17.1 Cells in Murine Colitis

Bo Hu, Hao Wang & Fei Xiao
Interleukin-17A (IL-17A)-expressing T cells, including T helper 17 (Th17) and T helper 17.1 (Th17.1) cells, play a significant role in inflammatory bowel diseases (IBDs). Identifying the mechanisms underlying the heterogeneity and plasticity of IL-17A-expressing T cells is crucial for understanding and controlling their pathogenicity. The role of E74 like ETS transcription factor 3 (ELF3) in regulating the pathogenicity of IL-17A-expressing T cells has not been studied before. Dextran sulfate sodium was used to induce acute...

Offshore Island Connection Line: A new perspective of coastal urban development boundary simulation and multi-scenario prediction

Fei He, Jun Yang, Yuqing Zhang, Dongqi Sun, Li Wang, Xiangming Xiao & Jianhong Xia
The urban development boundary (UDB) is a core issue in territorial spatial planning and remains a research focus in urban development. However, in the past, land use simulations of coastal cities have had some limitations. For example, new urban land outside the research boundary could not be effectively simulated, resulting in a large gap between the simulation results and reality. In this study, an artificial neural network (ANN) cellular automata (CA) model based on a...

Use of sponge iron dosing in baffled subsurface-flow constructed wetlands for treatment of wastewater treatment plant effluents during autumn and winter

Muyu Feng, Jinming Liang, Peng Wang, Ya’e Wang & Jie Li
Sponge iron (SI) is widely used in water treatment. As effluents from wastewater treatment plant (WWTP) require advanced treatment methodology, three forms of constructed wetlands (CWs): wetlands with sponge iron (SI), copper sulfate modified sponge iron (Cu/SI), and sponge iron coupled with solid carbon sources (C/SI), have been investigated in this paper for the removal effects of organic matter and nutrients in WWTP effluents, and the corresponding mechanisms have been analyzed. The results showed the...

An Additive Graphical Model for Discrete Data

Jun Tao, Bing Li & Lingzhou Xue
We introduce a nonparametric graphical model for discrete node variables based on additive conditional independence. Additive conditional independence is a three-way statistical relation that shares similar properties with conditional independence by satisfying the semi-graphoid axioms. Based on this relation we build an additive graphical model for discrete variables that does not suffer from the restriction of a parametric model such as the Ising model. We develop an estimator of the new graphical model via the...

Supplementary material.docx from Transcriptome analysis and mining of genes related to shade tolerance in foxtail millet (Setaria italica (L.) P. Beauv.)

Dan Liu, Yanjiao Cui, Zilong Zhao, Jing Zhang, Suying Li & Zhengli Liu
A stereo interplanting system with foxtail millet beneath chestnut trees is an effective planting method to raise the utilization of land in chestnut orchards, increase yields and improve quality of chestnut nuts. Consequently, exploration of genes involved in shade tolerance response in foxtail millet and breeding shade-tolerant varieties have become urgent issues. In this study, RNA-seq of leaf samples from two shade-tolerant varieties and three shade-intolerant varieties of foxtail millet at the booting stage was...

Additional file 4 of Microbiota and metabolites alterations in proximal and distal gastric cancer patients

Yan Yang, Daofeng Dai, Wen Jin, Yingying Huang, Yingzi Zhang, Yiran Chen, Wankun Wang, Wu Lin, Xiangliu Chen, Jing Zhang, Haohao Wang, Haibin Zhang & Lisong Teng
Additional file 4: Figure S3. Differential microbiota of gastric cancer tissues and non-tumor tissues. A Differential taxa from phylum to genus of Distal T and Distal N. B Differential taxa from phylum to genus of Proximal T and Proximal N.

Molecular epidemiology and clinical features of hand, foot and mouth disease requiring hospitalization after the use of enterovirus A71 inactivated vaccine in chengdu, China, 2017-2022: a descriptive study

Xiaoxia Duan, Chaoyong Zhang, Xiao Wang, Xueling Ren, Hongxia Peng, Xueqin Tang, Liangzhi Zhang, Zhenhua Chen, Yan Ye, Mengmou Zheng, Wanzhen Zhong, Xiyue Chen, Yilan Zeng, Ping Yuan & Lu Long
Three inactivated enterovirus A71 (EV-A71) vaccines have been widely vaccinated among children in the targeted age group in mainland China since mid-2016. However, comprehensive virological surveillance of hand, foot and mouth disease (HFMD) over multiple years after the use of EV-A71 vaccines has rarely been conducted. Using long-term data extracted from the Public Health and Clinical Center of Chengdu, we described the clinical, aetiological, and epidemiological characteristics of HFMD inpatients after the use of EV-A71...

Predictors of HbA1c reduction and hypoglycemia in type 2 diabetes mellitus individuals switching from premixed to basal insulin: an exploratory analysis of optimization study

Wenying Yang, Juan Du, Minlu Zhang, Jing Hou, Xia Zhang & Nan Cui
To identify population with type 2 diabetes mellitus (T2DM) who are more likely to benefit from switching to basal insulin (BI) treatment from premixed insulin. This secondary analysis included data from a previously published study (Optimization: NCT00693771) which was a single-arm, multicenter, 16 weeks, phase IV study. The analysis included participants with T2DM inadequately controlled with premixed insulin plus oral hypoglycemic drugs (OADs) who switched to BI plus OADs. Among the 297 participants included for...

Additional file 1 of Microbiota and metabolites alterations in proximal and distal gastric cancer patients

Yan Yang, Daofeng Dai, Wen Jin, Yingying Huang, Yingzi Zhang, Yiran Chen, Wankun Wang, Wu Lin, Xiangliu Chen, Jing Zhang, Haohao Wang, Haibin Zhang & Lisong Teng
Additional file 1: Table S1. Clinicopathological characteristics of patients with gastric cancer in this study. Table S2. Different microorganisms in Proximal T and Distal T compared to their respective non tumor samples. Table S3. Significant differences in metabolites between Distal T and Distal N. Table S4. Significant differences in metabolites between Proximal T and Proximal N. Table S5. Metabolic pathway enrichment of differential metabolites between Distal T and Distal N. Table S6. Metabolic pathway enrichment...

Additional file 1 of The efficacy and safety of acupuncture and nicotine replacement therapy for smoking cessation: study protocol for a randomized controlled trial

Qingsheng Wang, Runjing Dai, Hailiang Zhang, Xiaomei Jiang, Xiaojing Ma, Xiangrong Zhang, Shisan Bao, Dong Ren & Jingchun Fan
Supplementary file 1. SPIRIT Checklist for Trials.

Study on Physicochemical Properties and Potential Applications of Chemically Treated Luffa Sponge Fibers

Beibei Weng, Dao Cheng, Fangcheng Yuan, Xinzhou Wang, Fuli Wang, Hao Wang, Qingyang Zhang, Kaiting Zhang, Shanshan Wu, Yuhong Gao, Jiachen Wang, Yan Lv, Zicheng Wu, Yingquan Tan, Yong Guo & Yuxia Chen
To explore and expand the application of luffa sponge (LS) fiber, three methods were used to chemically modify the LS fibers. The nanoindentation (NI) results show that the LS fibers exhibit a high elastic modulus (12.4 GPa) and hardness (0.7 GPa). Upon treating the fibers with 5%NaOH-5%H2O2, the NI hardness of the fibers increases by 14.3%. However, when 10%NaOH-20%CH3COOH (method B) is used, the hardness of the cell walls decreases by 28.6%. In this case,...

Additional file 2 of Identification of HMGB2 associated with proliferation, invasion and prognosis in lung adenocarcinoma via weighted gene co-expression network analysis

Xie Qiu, Wei Liu, Yifan Zheng, Kai Zeng, Hao Wang, Haijun Sun & Jianhua Dai
Additional file 2: Figure S1. Original blot and images. Figure S2. HMGB2 expression is not correlated with survival of patients with LUSC.

Additional file 1 of TNFα and IFNγ rapidly activate PI3K-AKT signaling to drive glycolysis that confers mesenchymal stem cells enhanced anti-inflammatory property

Chenchang Xu, Chao Feng, Peiqing Huang, Yinghong Li, Rui Liu, Chunxiao Liu, Yuyi Han, Lei Chen, Yayun Ding, Changshun Shao & Yufang Shi
Additional file 1. Table S1. The primers used for real-time PCR.

Additional file 1 of Facilitators, barriers and strategies for health-system guidance implementation: a critical interpretive synthesis protocol

Qi Wang, Ying Zhu, Shitong Xie, Mohammad Golam Kibria, Qiangqiang Guo, Ahmed Atef Belal, Yanfei Li, Jingyi Zhang, Yaolong Chen, Holger J. Schünemann, Michael G. Wilson, Kehu Yang & John N. Lavis
Additional file 1. PRISMA-P 2015 checklist.

Additional file 1 of The diversity and evolutionary relationships of ticks and tick-borne bacteria collected in China

JunHua Tian, Xin Hou, MiHong Ge, HongBin Xu, Bin Yu, Jing Liu, RenFu Shao, Edward C. Holmes, ChaoLiang Lei & Mang Shi
Additional file 1: Table S1. Detailed information on the 96 tick libraries examined here. Figure S1. Gene arrangements in tick mitochondrial genomes across eight genera. There are 23 linear maps in 19 species of Haemaphysalis, nine in Amblyomma species, two in Bothriocroton species, three in two Hyalomma species, 13 in 10 Rhipicephalus species, 18 in 16 Ixodes species, one of Nuttalliellidae species and 26 linear maps of Argasid ticks. Each mitochondrial genome has 13 protein-coding...

Additional file 1 of Jin-Tian-Ge ameliorates ovariectomy-induced bone loss in rats and modulates osteoblastogenesis and osteoclastogenesis in vitro

Yi Shen, Na Wang, Qi Zhang, Yuling Liu, Qudi Wu, Yuqiong He, Yang Wang, Xiaoyan Wang, Qiming Zhao, Quanlong Zhang, Luping Qin & Qiaoyan Zhang
Additional file 1: Table S1. The correlation coefficient and coefficient T test between BMD and bone biomechanics.

Supplemental Material - Dynamic response control of centrifugal pendulum vibration absorber with motion-limiting device during startup in gravity field

Yi Zhang, Guangqiang Wu & Yiming Long
Supplemental Material for Dynamic response control of centrifugal pendulum vibration absorber with motion-limiting device during startup in gravity field by Yi Zhang, Guangqiang Wu, Yiming Long in Journal of Vibration and Control

Physical activity during pregnancy and adverse birth outcome: a prospective cohort study in China

Jinxiu Li, Dongping Huang, Jun Liang, Jiehua Chen, Lei Lei, Mengrui Lin, Kaili Wu, Suyang Xiao, Mingshuang Lai, Xiaoqiang Qiu, Zhengmin Qian, Michael G. Vaughn, Stephen Edward McMillin, GuangHui Dong, Xiaoyun Zeng & Shun Liu
Objectives The relationship between prenatal physical activity (PA) and adverse birth outcomes is still inconclusive. We aimed to investigate the association between PA during pregnancy and adverse birth outcomes by using data from the Guangxi Zhuang birth cohort (GZBC) in China. Study Design A total of 11,292 mother-infant pairs were included from GZBC in China. The information on PA status, intensity, adequacy, and volume and birth outcomes were collected. Multivariable linear and logistic regression models...

Registration Year

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  • Tianjin University
  • Chinese Academy of Medical Sciences & Peking Union Medical College
  • Shanghai Jiao Tong University
  • Sun Yat-sen University
  • Zhejiang University
  • Fudan University
  • Capital Medical University
  • Huazhong University of Science and Technology
  • Sichuan University
  • Chinese Academy of Sciences