2,791 Works

Spatial and temporal evolution of paleo-highs/lows of the permian strata and its petroleum significance in the Sichuan basin, SW China

Ben Feng, Yangwen Pei, Nan Su, Zhengshuo Miao, Yu Qiu, Hua Jiang & Han Liang
The Sichuan basin has a great potential for hydrocarbon exploration. In recent years, Permian strata have been identified as one of the main target strata for natural gas exploration in the Sichuan basin. Not only the source rocks are abundant, but also there are good reservoirs due to the wide and complex continental oceanic interaction. However, there are still many shortcomings, especially the relationship between the tectonic evolution and the hydrocarbon accumulation model. Therefore, this...

Additional file 1 of LncRNA XIST from the bone marrow mesenchymal stem cell derived exosome promotes osteosarcoma growth and metastasis through miR-655/ACLY signal

Guanghui Zhu, Yu Xia, Ziyue Zhao, Aoyu Li, Hui Li & Tao Xiao
Additional file 1: Figure S1. Characterization of BMSCs. A Morphology of BMSCs under light microscope; B, C Flow cytometry and statistical analysis of the positive rates of MSC-specific surface markers (CD29 and CD90) and a hematopoietic marker CD45 (n = 3); D The analysis of ALP level after osteogenesis induction 14d(n = 3); E The level of mineralized nodules analyzed with Alizarin red staining after osteogenesis induction 21d (n = 3); F The level of...

Additional file 2 of Association between single-nucleotide polymorphism rs145497186 related to NDUFV2 and lumbar disc degeneration: a pilot case–control study

Ziyu Wang, Lu Chen, Qinghui Li, Hengshuo Zhang, Yu Shan, Linzeng Qi, Hongliang Wang & Yunzhen Chen
Additional file 2: Table S2. Hardy-Weinberg Equilibrium Test of rs28742109, rs12955018, rs987850, rs8093805, rs12965084 and rs145497186 that related to NDUFV2.

Additional file 2 of Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

Mohd Hafidz Mahamad Maifiah, Yan Zhu, Brian T. Tsuji, Darren J. Creek, Tony Velkov & Jian Li
Additional file 2: Figure S1. Time-kill kinetics of polymyxin B (PolyB; 1 mg/L), rifampicin (Rif; 2 mg/L), and their combination against P. aeruginosa PAO1 at starting 600 nm (OD600) of ~ 0.5 (~ 108 CFU/mL). Figure S2. GO enrichment analysis of the significantly changed genes with the polymyxin B/rifampicin combination at (A) 1 h and (B) 24 h: (i) downregulation and (ii) upregulation of various biological processes. Figure S3. Overview of metabolic pathways of P....

Additional file 2 of One day versus two days of hepatic arterial infusion with oxaliplatin and fluorouracil for patients with unresectable hepatocellular carcinoma

Zhicheng Lai, Yexing Huang, Dongsheng Wen, Xuanjia Lin, Anna Kan, Qijiong Li, Wei Wei, Minshan Chen, Li Xu, Minke He & Ming Shi
Additional file 2: Table S1. Treatment administration. Table S2. Univariate and multivariate analysis of overall survival and progression-free survival. Table S3. Univariate and multivariate analysis of overall survival and progression-free survival in the PSM cohort. Table S4. Intrahepatic tumor response. Table S5. Baseline characteristics and tumor response within patients performing ELISA detection.

Additional file 4 of One day versus two days of hepatic arterial infusion with oxaliplatin and fluorouracil for patients with unresectable hepatocellular carcinoma

Zhicheng Lai, Yexing Huang, Dongsheng Wen, Xuanjia Lin, Anna Kan, Qijiong Li, Wei Wei, Minshan Chen, Li Xu, Minke He & Ming Shi
Additional file 4: Figure S2. Kaplan-Meier curves of overall survival in BCLC stage C patients receiving HAIC alone (A), HAIC + TKIs (B) and HAIC + TKIs + ICIs (C) in PSM cohort. Kaplan-Meier curves of progression-free survival in BCLC stage C patients receiving HAIC alone (D), HAIC + TKIs (E) and HAIC + TKIs + ICIs (F) in PSM cohort. CI, confidence interval; HR. hazard ratio; PSM, propensity score matching.

Additional file 1 of Silencing eL31 suppresses the progression of colorectal cancer via targeting DEPDC1

Gaowa Sharen, Xiongfeng Li, Jiaxin Sun, Lei Zhang, Wen Xi, Xiaodong Zhao, Fei Han, Longlong Jia, Rong A, Haidong Cheng & Mingxing Hou
Additional file 1: Figure S1. (A) The transfection efficiencies of sheL31-1 and sheL31-2 in HCT 116 cells were detected by qRT-PCR. (B) The transfection efficiencies of sheL31-1 and sheL31-2 in HCT 116 and RKO cells were evaluated through observing the fluorescence inside cells. Magnification times: 200×. (C) The densitometric analyses of Akt, P-Akt, CCND1, CDK6 and PIK3CA proteins expression. * P < 0.05, *** P < 0.001. Figure S2. (A) The volcano plot of gene...

Additional file 1 of Mechanistic insights into the health benefits of fish-oil supplementation against fine particulate matter air pollution: a randomized controlled trial

Lu Zhou, Yixuan Jiang, Zhijing Lin, Renjie Chen, Yue Niu & Haidong Kan
Supplementary Material 1

Additional file 1 of Mechanistic insights into the health benefits of fish-oil supplementation against fine particulate matter air pollution: a randomized controlled trial

Lu Zhou, Yixuan Jiang, Zhijing Lin, Renjie Chen, Yue Niu & Haidong Kan
Supplementary Material 1

Additional file 1 of Genetic engineering and raising temperature enhance recombinant protein production with the cdna1 promoter in Trichoderma reesei

Shanshan Jiang, Yue Wang, Qin Liu, Qinqin Zhao, Liwei Gao, Xin Song, Xuezhi Li, Yinbo Qu & Guodong Liu
Additional file 1: Table S1. Primers used for strain construction and verification in this study. Table S2. Primers used for qPCR in this study. Table S3. Copy numbers of poman5A gene in the constructed strains measured by qPCR. Figure S1. Map of plasmid pM5p.

Additional file 1 of Coexistence of chronic hyperalgesia and multilevel neuroinflammatory responses after experimental SCI: a systematic approach to profiling neuropathic pain

Lei Wang, Mehmet A. Gunduz, Ana T. Semeano, Enis C. Yılmaz, Feras A. H. Alanazi, Ozan B. Imir, Ulas Yener, Christian A. Arbelaez, Esteban Usuga & Yang D. Teng
Additional file 1: Table S1. Scores of spontaneous pain-related physical parameters.

Additional file 2 of Coexistence of chronic hyperalgesia and multilevel neuroinflammatory responses after experimental SCI: a systematic approach to profiling neuropathic pain

Lei Wang, Mehmet A. Gunduz, Ana T. Semeano, Enis C. Yılmaz, Feras A. H. Alanazi, Ozan B. Imir, Ulas Yener, Christian A. Arbelaez, Esteban Usuga & Yang D. Teng
Additional file 2: Table S2. Immunohistochemical reaction protocols.

Cloning of goat PGAM2 gene and its overexpression promotes the differentiation of intramuscular preadipocytes

Xiao Ma, Yuxue Wang, Xinyi Li, Jian Wang, Botao Wang, Yaqiu Lin & Yan Xiong
As a member of the PGAMs family, PGAM2 has been proved to catalyze the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. However, it is unclear whether PGAM2 has a role in regulating differentiation in goat intramuscular preadipocytes. Here, this study was carried to clone the open reading frame (ORF) of goat PGAM2, elucidate its molecular and expressional characteristics, and evaluate the involvement in adipogenesis of intramuscular preadipocytes. According to our...

Cloning of goat PGAM2 gene and its overexpression promotes the differentiation of intramuscular preadipocytes

Xiao Ma, Yuxue Wang, Xinyi Li, Jian Wang, Botao Wang, Yaqiu Lin & Yan Xiong
As a member of the PGAMs family, PGAM2 has been proved to catalyze the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. However, it is unclear whether PGAM2 has a role in regulating differentiation in goat intramuscular preadipocytes. Here, this study was carried to clone the open reading frame (ORF) of goat PGAM2, elucidate its molecular and expressional characteristics, and evaluate the involvement in adipogenesis of intramuscular preadipocytes. According to our...

Supplementary document for Compact structured illumination microscopy with high spatial frequency diffractive lattice patterns - 6069450.pdf

cilong zhang, Ning Xu & Qiaofeng Tan
supplemental document

Additional file 3 of Copy number variant analysis for syndromic congenital heart disease in the Chinese population

Ping Li, Weicheng Chen, Mengru Li, Zhengshan Zhao, Zhiyu Feng, Han Gao, Meijiao Suo, Ziqing Xu, Guixiang Tian, Feizhen Wu, Sheng Wei & Guoying Huang
Additional file 3. Additional methods. Pathway analysis of the prioritized genes, the databases, and the dataset.

Additional file 3 of Copy number variant analysis for syndromic congenital heart disease in the Chinese population

Ping Li, Weicheng Chen, Mengru Li, Zhengshan Zhao, Zhiyu Feng, Han Gao, Meijiao Suo, Ziqing Xu, Guixiang Tian, Feizhen Wu, Sheng Wei & Guoying Huang
Additional file 3. Additional methods. Pathway analysis of the prioritized genes, the databases, and the dataset.

Additional file 5 of Copy number variant analysis for syndromic congenital heart disease in the Chinese population

Ping Li, Weicheng Chen, Mengru Li, Zhengshan Zhao, Zhiyu Feng, Han Gao, Meijiao Suo, Ziqing Xu, Guixiang Tian, Feizhen Wu, Sheng Wei & Guoying Huang
Additional file 5. Fig. S1. Gene ontology analysis of the 1249 candidate genes (1129 matched).

Additional file 9 of Copy number variant analysis for syndromic congenital heart disease in the Chinese population

Ping Li, Weicheng Chen, Mengru Li, Zhengshan Zhao, Zhiyu Feng, Han Gao, Meijiao Suo, Ziqing Xu, Guixiang Tian, Feizhen Wu, Sheng Wei & Guoying Huang
Additional file 9. Fig. S2. Interaction analyses of prioritized genes by different tools.

Additional file 1 of Analysis of different adipose depot gene expression in cachectic patients with gastric cancer

Jun Han, Zuoyou Ding, Qiulin Zhuang, Lei Shen, Fan Yang, Szechun Sah & Guohao Wu
Additional File 1. Figure S1: A representative CT image at the third lumbar vertebra (L3) marked with different body composition. Skeletal muscle (SM) in red; subcutaneous adipose tissue (SAT) in blue; visceral adipose tissue (VAT) in yellow; intramuscular adipose tissue (IMAT) in green. Figure S2: Gene expression distributions of each sample for RNA sequencing. Figure S3: Representative images of SAT and VAT from normal and cachectic mice.

Additional file 11 of A point-of-care ultrasound education curriculum for pediatric critical care medicine

Vidit Bhargava, Bereketeab Haileselassie, Samuel Rosenblatt, Mark Baker, Kevin Kuo & Erik Su
Additional file 11. High-quality, free open access resources for point-of-care ultrasound education

Additional file 2 of A point-of-care ultrasound education curriculum for pediatric critical care medicine

Vidit Bhargava, Bereketeab Haileselassie, Samuel Rosenblatt, Mark Baker, Kevin Kuo & Erik Su
Additional file 2. Pre-course knowledge assessment of the learners

Additional file 1 of Phylogenomics, plastome degradation and mycoheterotrophy evolution of Neottieae (Orchidaceae), with emphasis on the systematic position and Loess Plateau-Changbai Mountains disjunction of Diplandrorchis

Huan-Wen Peng, Lian Lian, Jun Zhang, Andrey S. Erst & Wei Wang
Additional file 1: Table S1. Taxa, distribution, and GenBank accession numbers for the sequences used in this study. Table S2. Comparison of the fit of different models of biogeographical range evolution and model-specific estimates for the different parameters. Table S3. Manual dispersal multipliers. Table S4. Georeferenced records of D. sinica used for species distribution modeling.

Additional file 1 of Phylogenomics, plastome degradation and mycoheterotrophy evolution of Neottieae (Orchidaceae), with emphasis on the systematic position and Loess Plateau-Changbai Mountains disjunction of Diplandrorchis

Huan-Wen Peng, Lian Lian, Jun Zhang, Andrey S. Erst & Wei Wang
Additional file 1: Table S1. Taxa, distribution, and GenBank accession numbers for the sequences used in this study. Table S2. Comparison of the fit of different models of biogeographical range evolution and model-specific estimates for the different parameters. Table S3. Manual dispersal multipliers. Table S4. Georeferenced records of D. sinica used for species distribution modeling.

Additional file 2 of Phylogenomics, plastome degradation and mycoheterotrophy evolution of Neottieae (Orchidaceae), with emphasis on the systematic position and Loess Plateau-Changbai Mountains disjunction of Diplandrorchis

Huan-Wen Peng, Lian Lian, Jun Zhang, Andrey S. Erst & Wei Wang
Additional file 2: Fig. S1. Evolutionary inference of nutrition types for Neottieae. Numbers in bold near branches indicate the node number, as referred to Fig. 3. Large pie charts show the relative probabilities of alternative ancestral states obtained by BayesTraits. Fig. S2. Ancestral range reconstruction for Neottieae using BioGeoBEARS under the statistical DEC model. Numbers in bold near branches indicate the node number, as referred to Fig. 3. Large pie charts show the relative probabilities...

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