139 Works

Clinical features and risk factors associated with acute respiratory distress syndrome in pregnant women diagnosed with COVID-19: a multi-center case-control study

Soudabeh Kazemi Aski, Amir Hossein Norooznezhad, Amir A. Shamshirsaz, Shayan Mostafaei, Ashraf Aleyasin, Seyedeh Maedeh Nabavian, Shohreh Alimohammadi, Roghaye Ahangari, Shideh Ariana, Fahimeh Ghotbizadeh, Fatemeh Tara, Parichehr Pooransari, Mahboobeh Gharib Laki, Elaheh Zarean, Zahra Soleimani, Alireza Saliminia, Arash Havaei, Razieh Akbari, Masoud Ramezani, Azam Soleimani, Mahsa Naemi, Alireza A. Shamshirsaz & Sedigheh Hantoushzadeh
The aim of this study was to evaluate differences in clinical features and laboratory parameters in critically ill pregnant women with acute respiratory distress syndrome (ARDS) compared to moderate and severe pregnant women with coronavirus disease-2019 (COVID-19) but without ARDS. This was a retrospective multicenter study of all pregnant women with COVID-19 diagnosed with ARDS between February 15, and May 1, 2020 in nine level III maternity centers in Iran (ARDS group). The control COVID-19...

Trigonella teheranica: a valuable source of phytochemicals with antibacterial, antioxidant and cytotoxic properties

Fatemeh Kiashi, Fatemeh Momeni Nasab, Saeed Tavakoli, Majid Aghaahmadi, Saied Goodarzi, Mostafa Pirali Hamedani, Fereshteh Heidari, Abbas Hadjiakhoondi & Zahra Tofighi
Trigonella genus is a member of Fabaceae family, which is used as medicinal plant. The aim of this study was investigation of phytochemicals and some biological activities of Trigonella teheranica for the first time. The essential oils (EOs) of different parts (leaves, fruits and roots) were obtained and analyzed by GC-MS. Also, their chloroform and methanol extracts were prepared, too. The antimicrobial effects, antioxidant activities and cytotoxic effects against cancer (MDA-MB-231, MRC5 and HT-29) cell...

Zonulin levels in complicated pregnancy: a systematic review and meta-analysis

Mojtaba Daneshvar, Anahita Yadegari, Davide Giuseppe Ribaldone, Mohaddeseh Hasanzadeh & Kurosh Djafarian
Zonulin is a novel biomarker of intestinal permeability. The existing data suggest that upregulation of zonulin might be linked to systemic inflammation and pregnancy complications. A systematic search was performed in medical electronic databases to identify eligible studies that reported circulating zonulin levels in complicated pregnancies compared to controls. Eight studies with 1196 serum samples of pregnant women were included in the systematic review. Meta-analysis on four studies revealed a significant increase in serum zonulin...

Additional file 3 of The burden of chronic respiratory disease and attributable risk factors in North Africa and Middle East: findings from global burden of disease study (GBD) 2019

Aida Fallahzadeh, Yeganeh Sharifnejad Tehrani, Ali Sheikhy, Seyyed-Hadi Ghamari, Esmaeil Mohammadi, Sahar Saeedi Moghaddam, Zahra Esfahani, Maryam Nasserinejad, Parnian Shobeiri, Mohammad-Mahdi Rashidi, Nazila Rezaei, Mahsa Heidari-Foroozan, Negar Rezaei, Bagher Larijani & Farshad Farzadfar
Additional file 3: Table S3. Age-standardized rate of incidence, prevalence, deaths, DALYs, YLLs, and YLDs due to CRDs in North Africa and Middle East countries between 1990 and 2019, with percentage change by sex.

Additional file 3 of The burden of chronic respiratory disease and attributable risk factors in North Africa and Middle East: findings from global burden of disease study (GBD) 2019

Aida Fallahzadeh, Yeganeh Sharifnejad Tehrani, Ali Sheikhy, Seyyed-Hadi Ghamari, Esmaeil Mohammadi, Sahar Saeedi Moghaddam, Zahra Esfahani, Maryam Nasserinejad, Parnian Shobeiri, Mohammad-Mahdi Rashidi, Nazila Rezaei, Mahsa Heidari-Foroozan, Negar Rezaei, Bagher Larijani & Farshad Farzadfar
Additional file 3: Table S3. Age-standardized rate of incidence, prevalence, deaths, DALYs, YLLs, and YLDs due to CRDs in North Africa and Middle East countries between 1990 and 2019, with percentage change by sex.

Additional file 1 of Design, synthesis, in vitro, and in silico biological evaluations of coumarin-indole hybrids as new anti-α-glucosidase agents

Davood Rezapour Niri, Mohammad Hosein Sayahi, Somayeh Behrouz, Ali Moazzam, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Bagher Larijani, Hossein Rastegar, Maryam Mohammadi-Khanaposhtani & Mohammad Mahdavi
Additional file 1. Images of 1H NMR and 13C NMR of the new synthesized compounds 5a-m and IC50 graphs of these compounds are available in the Supporting Information.

Additional file 1 of Design and synthesis of novel ureido and thioureido conjugated hydrazone derivatives with potent anticancer activity

Nasrin Nassiri Koopaei, Mehrasa Shademani, Nasrin Shirzad Yazdi, Raheleh Tahmasvand, Mina Dehbid, Mansur Nassiri Koopaei, Homa Azizian, Zahra Mousavi, Ali Almasirad & Mona Salimi
Additional file 1. Spectral data including FT-IR,1HNMR, 13CNMR and Mass for compounds (4a–4i).

Additional file 1 of The burden of chronic obstructive pulmonary disease and its attributable risk factors in the Middle East and North Africa region, 1990–2019

Hamidreza Feizi, Mahasti Alizadeh, Seyed Aria Nejadghaderi, Maryam Noori, Mark J. M. Sullman, Javad Ahmadian Heris, Ali-Asghar Kolahi, Gary S. Collins & Saeid Safiri
Additional file 1: Table S1. Health states for chronic obstructive pulmonary disease and the associated disability weights from the Global Burden of Disease 2019 Study.

Additional file 3 of The burden of chronic obstructive pulmonary disease and its attributable risk factors in the Middle East and North Africa region, 1990–2019

Hamidreza Feizi, Mahasti Alizadeh, Seyed Aria Nejadghaderi, Maryam Noori, Mark J. M. Sullman, Javad Ahmadian Heris, Ali-Asghar Kolahi, Gary S. Collins & Saeid Safiri
Additional file 3: Table S3. Deaths of chronic obstructive pulmonary disease in 1990 and 2019 for both sexes and percentage change in age-standardised rates (ASRs) per 100,000 in the Middle East and North Africa region (generated from data available from http://ghdx.healthdata.org/gbd-results-tool ).

Additional file 4 of The burden of chronic obstructive pulmonary disease and its attributable risk factors in the Middle East and North Africa region, 1990–2019

Hamidreza Feizi, Mahasti Alizadeh, Seyed Aria Nejadghaderi, Maryam Noori, Mark J. M. Sullman, Javad Ahmadian Heris, Ali-Asghar Kolahi, Gary S. Collins & Saeid Safiri
Additional file 4: Table S4. DALYs due to chronic obstructive pulmonary disease in 1990 and 2019 for both sexes and percentage change in age-standardised rates (ASRs) per 100,000 in the Middle East and North Africa region (generated from data available from http://ghdx.healthdata.org/gbd-results-tool ).

Additional file 1 of Design, synthesis and evaluation of novel 1,2,4-triazole derivatives as promising anticancer agents

Leila Emami, Sara Sadeghian, Ayyub Mojaddami, Soghra khabnadideh, Amirhossein Sakhteman, Hossein Sadeghpour, Zeinab Faghih, Masood Fereidoonnezhad & Zahra Rezaei
Additional file 1: Figures S1–S58

Additional file 1 of Design, synthesis and evaluation of novel 1,2,4-triazole derivatives as promising anticancer agents

Leila Emami, Sara Sadeghian, Ayyub Mojaddami, Soghra khabnadideh, Amirhossein Sakhteman, Hossein Sadeghpour, Zeinab Faghih, Masood Fereidoonnezhad & Zahra Rezaei
Additional file 1: Figures S1–S58

Additional file 6 of The burden of chronic obstructive pulmonary disease and its attributable risk factors in the Middle East and North Africa region, 1990–2019

Hamidreza Feizi, Mahasti Alizadeh, Seyed Aria Nejadghaderi, Maryam Noori, Mark J. M. Sullman, Javad Ahmadian Heris, Ali-Asghar Kolahi, Gary S. Collins & Saeid Safiri
Additional file 6: Figure S2. The percentage change in the age-standardised death of chronic obstructive pulmonary disease in the Middle East and North Africa region from 1990 to 2019, by sex and country (generated from data available from http://ghdx.healthdata.org/gbd-results-tool ).

Additional file 2 of Detection of Toxocara species larvae in four Iranian free-range broiler farms

Elham Shokri, Ali Haniloo, Mohammad Zibaei, Ali Pezeshki, Kamyar Mansori & Kensuke Taira
Additional file 2. STROBE Statement Checklist of items that should be included in reports of cross-sectional studies.

Additional file 2 of High-density lipoprotein cholesterol efflux capacity in patients with obstructive sleep apnea and its relation with disease severity

Reza Fadaei, Samaneh Mohassel Azadi, Eric Rhéaume & Habibolah Khazaie
Additional file 2: S Figure 2. Cholesterol efflux capacities according to BMI categories. a) Total, b) Non-ABCA1, and c) ABCA1 CEC have shown no considerable change between normal weight (BMI < 25) and overweight (BMI > 25) in the whole population. d) Total CEC, e) Non-ABCA1 CEC, and f) ABCA1 CEC demonstrated no change in normal weight (BMI < 25) compared with overweight (BMI > 25) in both OSA patients and controls.

Additional file 1 of Home care nurses’ perception of the challenges they faced during the COVID-19 pandemic: a qualitative study

Tahereh Najafi Ghezeljeh, Sahar Keyvanloo Shahrestanaki, Zahra Amrollah Majdabadi kohne & Ehsan Fakhari
Additional file 1: Supplement Table1. Saturation grid.

Additional file 1 of Synthesis and bioactivities evaluation of quinazolin-4(3H)-one derivatives as α-glucosidase inhibitors

Mahshid Moheb, Aida Iraji, Navid Dastyafteh, Minoo Khalili Ghomi, Milad Noori, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Fatemeh Rasekh, Bagher Larijani, Kamiar Zomorodian, Seyed Esmaeil Sadat-Ebrahimi & Mohammad Mahdavi
Additional file 1: Figure S1. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-phenylacetamide (7a). Figure S2. N-(2-fluorophenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7b). Figure S3. N-(4-fluorophenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7c). Figure S4. N-(2-chlorophenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7d). Figure S5. N-(3-chlorophenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7e). Figure S6. N-(4-chlorophenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7f). Figure S7. N-(4-bromophenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7g). Figure S8. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-(o-tolyl)acetamide (7 h). Figure S9. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-(p-tolyl)acetamide (7i). Figure S10. N-(2,6-dimethylphenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7j). Figure S11. N-(4-ethylphenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7k). Figure S12. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-(4-methoxyphenyl)acetamide (7 l). Figure S13. N-(4-hydroxyphenyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7m). Figure S14. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-(4-nitrophenyl)acetamide (7n). Figure S15. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-(naphthalen-2-yl)acetamide (7o). Figure S16. 2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)-N-(4-methylbenzyl)acetamide (7p). Figure S17. N-(4-fluorobenzyl)-2-(2-methoxy-4-(4-oxo-3,4-dihydroquinazolin-2-yl)phenoxy)acetamide (7q). Figure S18....

Additional file 1 of Off-pump versus on-pump coronary artery bypass graft surgery outcomes in patients with severe left ventricle dysfunction: inverse probability weighted study

Ali Sheikhy, Aida Fallahzadeh, Khalil Forouzannia, Mina Pashang, Masih Tajdini, Shahram Momtahen, Soheil Mansourian, Mahmoud Shirzad, Saeed Sadeghian & Kaveh Hosseini
Additional file 1. Table S1. Variables used in propensity score estimations. Fig. S1. C-statistic for propensity score modeling. Fig. S2. Estimated Propensity scores. Table S2. Standardized mean differences (SMD) percentage of characteristic variables.

Developing low-achieving medical students’ self-regulated learning using a combined learning diary and explicit training intervention

Zahra Zarei Hajiabadi, Roghayeh Gandomkar, Amir Ali Sohrabpour & John Sandars
The development of self-regulated learning (SRL) is an essential educational component of remediation for low-achieving students. The aim of this study was to design, implement, and evaluate a longitudinal SRL intervention combining both a structured learning diary and explicit SRL training in a cohort of low-achieving undergraduate medical students. A mixed methods quasi-experimental study was conducted, with a pretest–posttest study in the intervention group and comparison of the GPA and course grade of the intervention...

Developing low-achieving medical students’ self-regulated learning using a combined learning diary and explicit training intervention

Zahra Zarei Hajiabadi, Roghayeh Gandomkar, Amir Ali Sohrabpour & John Sandars
The development of self-regulated learning (SRL) is an essential educational component of remediation for low-achieving students. The aim of this study was to design, implement, and evaluate a longitudinal SRL intervention combining both a structured learning diary and explicit SRL training in a cohort of low-achieving undergraduate medical students. A mixed methods quasi-experimental study was conducted, with a pretest–posttest study in the intervention group and comparison of the GPA and course grade of the intervention...

Evaluation of pregnancy outcomes in mothers with COVID-19 infection: a systematic review and meta-analysis

Masoumeh Simbar, Sima Nazarpour & Ali Sheidaei
Pregnant women are one of the endangered groups who need special attention in the COVID-19 epidemic. We conducted a systematic review and summarised the studies that reported adverse pregnancy outcomes in pregnant women with COVID-19 infection. A literature search was performed in PubMed and Scopus up to 1 September 2022, for retrieving original articles published in the English language assessing the association between COVID-19 infection and adverse pregnancy outcomes. Finally, in this review study, of...

Soy isoflavone intake and risk of cardiovascular disease in adults: A systematic review and dose-response meta-analysis of prospective cohort studies

Sina Naghshi, Helda Tutunchi, Mojtaba Yousefi, Fatemeh Naeini, Sara Mobarak, Masoomeh Asadi & Omid Sadeghi
We examined the association between soy isoflavone intake and risk of cardiovascular disease (CVD) outcomes in adults. We searched the online databases for relevant studies published up to September 2021. In total, 13 publications were included in the systematic review and 12 in the meta-analysis. We found that a high intake of soy isoflavones was significantly associated with a lower risk of coronary heart disease (CHD) among whole populations (Pooled RR: 0.92, 95% CI: 0.85–0.99,...

sj-docx-1-ehi-10.1177_11786302231151538 – Supplemental material for Mortality Risk Related to Heatwaves in Dezful City, Southwest of Iran

Hamidreza Aghababaeian, Abbas Ostadtaghizadeh, Ali Ardalan, Ali Asgary, Mehry Akbary, Mir Saeed Yekaninejad, Rahim Sharafkhani & Carolyn Stephens
Supplemental material, sj-docx-1-ehi-10.1177_11786302231151538 for Mortality Risk Related to Heatwaves in Dezful City, Southwest of Iran by Hamidreza Aghababaeian, Abbas Ostadtaghizadeh, Ali Ardalan, Ali Asgary, Mehry Akbary, Mir Saeed Yekaninejad, Rahim Sharafkhani and Carolyn Stephens in Environmental Health Insights

COVID-19 related knowledge, anxiety, depression and physical activity among Iranian people with relapsing-remitting multiple sclerosis during COVID-19 pandemic: an online cross-sectional survey

Shabnam ShahAli, Haniyeh Choobsaz & Reyhane Ebrahimi
To determine COVID-19 related knowledge, assess the anxiety/depression and physical activity and their association with demographic variables among Iranian people with relapsing-remitting multiple sclerosis (MS) during the COVID-19 pandemic. It also attempted to find the association between COVID-19 related knowledge and physical activity with anxiety and depression. One hundred and forty MS patients participated in an online cross-sectional survey. The survey, including the COVID-19 related knowledge questionnaire, hospital anxiety, depression scale and International Physical Activity...

Integrated Fuzzy AHP-TOPSIS for selecting the best color removal process using carbon-based adsorbent materials: multi-criteria decision making vs. systematic review approaches and modeling of textile wastewater treatment in real conditions

Ali Azari, Ramin Nabizadeh, Amir Hossein Mahvi & Simin Nasseri
Here, Fuzzy AHP-TOPSIS methodology proposed for selecting the best colour treatment process using carbon-based adsorbent materials. Cost, safety, accessibility, reuse and adsorption capacity were identified as the main criteria for decision making. The priority of the criteria based on the experts’ opinions ordered as accessibility, reuse, adsorption capacity, environment safety, human safety, material cost, equipment cost with BNP = 0.250, 0.217, 0.172, 0.144, 0.105, 0.070 and 0.049, respectively. The consistency ratio was found 0.7% (less...

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