196 Works

Hepatoprotective mechanism of Silybum marianum on nonalcoholic fatty liver disease based on network pharmacology and experimental verification

Guoyan Jiang, Chunhong Sun, Xiaodong Wang, Jie Mei, Chen Li, Honghong Zhan, Yixuan Liao, Yongjun Zhu & Jingxin Mao
The study aimed to identify the key active components in Silybum marianum (S. marianum) and determine how they protect against nonalcoholic fatty liver disease (NAFLD). TCMSP, DisGeNET, UniProt databases, and Venny 2.1 software were used to identify 11 primary active components, 92 candidate gene targets, and 30 core hepatoprotective gene targets in this investigation, respectively. The PPI network was built using a string database and Cytoscape 3.7.2. The KEGG pathway and GO biological process enrichment,...

Rare earth elements in the iron-oxide apatite (IOA) deposit: insights from apatite

Shengchao Yan & Wei Liu
Kiruna-type or IOA deposits are characterized by magnetite-apatite-actinolite associations and may contain considerable amounts of rare earth elements (REEs) that can be exploited as by-products. REEs in the Kiruna-type deposit, heterogeneously distributed, are mainly hosted in phosphates (e.g. apatite). Published data of apatite, together with other evidence, can be used to decipher the source, enrichment mechanism, and post-ore modification of REEs in the Kiruna-type deposits. Sr isotopes and melt inclusions compositions of apatite, together with...

Ubiquitin-specific peptidase 2 inhibits epithelial-mesenchymal transition in clear cell renal cell carcinoma metastasis by downregulating the NF-κB pathway

Jiachen Duan, Mengyuan Jin, Dongjing Yang, Jihua Shi, Jie Gao, Danfeng Guo, Hongwei Tang, Shuijun Zhang & Baoping Qiao
Clear cell renal cell carcinoma, the most common type of renal cancer, is associated with poor survival. Ubiquitin-specific peptidase 2 regulates the molecular mechanisms of cancer cells. However, its mechanism in clear cell renal cell carcinoma remains unclear. Quantitative real-time polymerase chain reaction, enzyme-linked immunosorbent assay, and immunohistochemistry were performed to assess ubiquitin-specific peptidase 2 expression in human clear cell renal cell carcinoma samples. Ubiquitin-specific peptidase 2 was weakly expressed in clear cell renal cell...

Implementation of novel boolean logic gates for IMPLICATION and XOR functions using riboregulators

Chaoxin Chen, Qi Wu, Qingying Ke, Ting Wang, Yifan Zhang, Feiwen Wei, Xiaolong Wang & Guanglei Liu
To date, several different types of synthetic genetic switches, including riboregulators, riboswitches, and toehold switches, have been developed to construct AND, OR, NOT, NAND, NOR, and NOT IMPLICATION (NIMP) gates. The logic gate can integrate multiple input signals following a set of algorithms and generate a response only if strictly defined conditions are met. However, there are still some logic gates that have not been implemented but are necessary to build complex genetic circuits. Here,...

Additional file 2 of Identification of HMGB2 associated with proliferation, invasion and prognosis in lung adenocarcinoma via weighted gene co-expression network analysis

Xie Qiu, Wei Liu, Yifan Zheng, Kai Zeng, Hao Wang, Haijun Sun & Jianhua Dai
Additional file 2: Figure S1. Original blot and images. Figure S2. HMGB2 expression is not correlated with survival of patients with LUSC.

Additional file 1 of Comparative clinical outcome following individualized follitropin delta dosing in Chinese women undergoing ovarian stimulation for in vitro fertilization /intracytoplasmic sperm injection

Rui Yang, Yunshan Zhang, Xiaoyan Liang, Xueru Song, Zhaolian Wei, Jianqiao Liu, Yezhou Yang, Jichun Tan, Qingxue Zhang, Yingpu Sun, Wei Wang, Weiping Qian, Lei Jin, Shuyu Wang, Yang Xu, Jing Yang, Marie Goethberg, Bernadette Mannaerts, Wen Wu, Zugeng Zheng & Jie Qiao
Additional file 1: Additional Figure 1. Study design and study timeline. AE, adverse event; OHSS, ovarian hyperstimulation syndrome; GnRH, gonadotropin-releasing hormone

Use of sponge iron dosing in baffled subsurface-flow constructed wetlands for treatment of wastewater treatment plant effluents during autumn and winter

Muyu Feng, Jinming Liang, Peng Wang, Ya’e Wang & Jie Li
Sponge iron (SI) is widely used in water treatment. As effluents from wastewater treatment plant (WWTP) require advanced treatment methodology, three forms of constructed wetlands (CWs): wetlands with sponge iron (SI), copper sulfate modified sponge iron (Cu/SI), and sponge iron coupled with solid carbon sources (C/SI), have been investigated in this paper for the removal effects of organic matter and nutrients in WWTP effluents, and the corresponding mechanisms have been analyzed. The results showed the...

Additional file 7 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 7: Table S2. The primer sequences used in the study.

Additional file 3 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 3: Fig. S3. The time dependent ROC curves for other three prognostic models. A Time dependent ROC curves for immune-related gene signature in the TCGA GBM cohort. B Time dependent ROC curves for pyroptosis-related gene signature in the TCGA GBM cohort. C Time dependent ROC curves for autophagy-related gene signature in the TCGA GBM cohort.

Additional file 4 of Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments

Jun Su, Yue Li, Qing Liu, Gang Peng, Chaoying Qin & Yang Li
Additional file 4: Fig. S4. Validation of independence of our risk score as a prognostic factor. A The forest plot showed the univariate cox analysis using risk score, age, radiotherapy, TMZ chemotherapy, and gender as variates in the GSE16011 GBM cohort. B The forest plot showed the multivariate cox analysis using risk score, age, radiotherapy, and TMZ chemotherapy as variates in the GSE16011 GBM cohort. C Stratified OS analysis in GSE16011 GBM patients with different...

Additional file 4 of miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Xunwei Lai, Yang Wang, Xiaokang wang, Bin Liu & Limin Rong
Additional file 4. miRNA sequences.

Additional file 5 of miR-146a-5p-modified hUCMSC-derived exosomes facilitate spinal cord function recovery by targeting neurotoxic astrocytes

Xunwei Lai, Yang Wang, Xiaokang wang, Bin Liu & Limin Rong
Additional file 5. Coding Sequence of Irak1 and Traf6 Genes.

Additional file 1 of Intervention time decides the status of autophagy, NLRP3 activity and apoptosis in macrophages induced by ox‐LDL

Liang Zheng, Hongbiao Xu, Fufu Zheng, Yuanhui Lai, Jie Li, Weiming Lv, Zuojun Hu & Wenjian Wang
Additional file 1. FigS1. Intracellular lipid accumulation is alteredafter exposure to different concentrations and durations of ox‐LDL incubation.

Additional file 3 of Evolution of the CBL and CIPK gene families in Medicago: genome-wide characterization, pervasive duplication, and expression pattern under salt and drought stress

Xiao-Xia Zhang, Xiao-Long Ren, Xiao-Tong Qi, Zhi-Min Yang, Xiao-Lei Feng, Tian Zhang, Hui-Jie Wang, Peng Liang, Qi-Ying Jiang, Wen-Jun Yang, Yuan Fu, Min Chen, Zhi-Xi Fu & Bo Xu
Additional file 3: Figure S1. Chromosomal localization of the CBL and CIPK genes in M. sativa spp. sativa.

Additional file 3 of Evolution of the CBL and CIPK gene families in Medicago: genome-wide characterization, pervasive duplication, and expression pattern under salt and drought stress

Xiao-Xia Zhang, Xiao-Long Ren, Xiao-Tong Qi, Zhi-Min Yang, Xiao-Lei Feng, Tian Zhang, Hui-Jie Wang, Peng Liang, Qi-Ying Jiang, Wen-Jun Yang, Yuan Fu, Min Chen, Zhi-Xi Fu & Bo Xu
Additional file 3: Figure S1. Chromosomal localization of the CBL and CIPK genes in M. sativa spp. sativa.

Additional file 1 of Functional analysis of the dehydratase domains of the PUFA synthase from Emiliania huxleyi in Escherichia coli and Arabidopsis thaliana

Bihan Chen, Feng Wang, Xi Xie, Huifan Liu, Dongjie Liu, Lukai Ma, Gengsheng Xiao & Qin Wang
Additional file 1: Table S1. Production of SFAs and UFAs in wild type Escherichia coli Rosetta overexpressing EhDH domains. Table S2. Production of SFAs and UFAs in wild-type Escherichia coli Rosetta overexpressing the mutated EhDH domains. Table S3. Primers used for DH domain amplifications. Table S4. Primers used for site-directed mutagenesis of DH domains. Table S5. Primers used for plant experiment. Figure S1. Expression of recombinant proteins when induced with 0.2 mM IPTG in Escherichia...

sj-docx-1-jet-10.1177_15266028221133700 – Supplemental material for Management Strategy and Radiologic Outcomes of Symptomatic Spontaneous Isolated Superior Mesenteric Artery Dissection Based on Angiographic Classification: The Follow-Up Experience in a Single Center

Zihui Yuan, Guofu Hu, Shi Sheng, Yun You & Jian Wang
Supplemental material, sj-docx-1-jet-10.1177_15266028221133700 for Management Strategy and Radiologic Outcomes of Symptomatic Spontaneous Isolated Superior Mesenteric Artery Dissection Based on Angiographic Classification: The Follow-Up Experience in a Single Center by Zihui Yuan, Guofu Hu, Shi Sheng, Yun You and Jian Wang in Journal of Endovascular Therapy

Additional file 11 of Evolution of the CBL and CIPK gene families in Medicago: genome-wide characterization, pervasive duplication, and expression pattern under salt and drought stress

Xiao-Xia Zhang, Xiao-Long Ren, Xiao-Tong Qi, Zhi-Min Yang, Xiao-Lei Feng, Tian Zhang, Hui-Jie Wang, Peng Liang, Qi-Ying Jiang, Wen-Jun Yang, Yuan Fu, Min Chen, Zhi-Xi Fu & Bo Xu
Additional file 11: Figure S6. Expression of CBL genes in roots of M. sativa spp. sativa when exposed to salt and drought stress.

Supplementary document for An enhanced self-powered ion-modulated photodetector based on asymmetric composite structure of superionic conductor RbAg4I5 and graphene - 6021357.pdf

Pengfei Wang, Duanhao Huang, Hao Liu, Yu Liu, Jun Yin, feng huang & Jia-Lin Sun
Supplement 1

Cloning of goat PGAM2 gene and its overexpression promotes the differentiation of intramuscular preadipocytes

Xiao Ma, Yuxue Wang, Xinyi Li, Jian Wang, Botao Wang, Yaqiu Lin & Yan Xiong
As a member of the PGAMs family, PGAM2 has been proved to catalyze the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. However, it is unclear whether PGAM2 has a role in regulating differentiation in goat intramuscular preadipocytes. Here, this study was carried to clone the open reading frame (ORF) of goat PGAM2, elucidate its molecular and expressional characteristics, and evaluate the involvement in adipogenesis of intramuscular preadipocytes. According to our...

Cloning of goat PGAM2 gene and its overexpression promotes the differentiation of intramuscular preadipocytes

Xiao Ma, Yuxue Wang, Xinyi Li, Jian Wang, Botao Wang, Yaqiu Lin & Yan Xiong
As a member of the PGAMs family, PGAM2 has been proved to catalyze the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. However, it is unclear whether PGAM2 has a role in regulating differentiation in goat intramuscular preadipocytes. Here, this study was carried to clone the open reading frame (ORF) of goat PGAM2, elucidate its molecular and expressional characteristics, and evaluate the involvement in adipogenesis of intramuscular preadipocytes. According to our...

Sensitive Colorimetric Determination of Cyromazine Using a Gold Nanoparticle (Au NP) Based Sensor with Smartphone Detection

Qiang Shi, Ting Wang, Ying Zheng, Qian Guo, Bing Wang & Sujuan Zhu
A highly sensitive colorimetric sensor based on the aggregation of gold nanoparticles (Au NPs) and a smartphone camera as detector is reported for the determination of cyromazine. In the presence of cyromazine, a decrease in the characteristic SPR absorbance peak of Au NPs is observed at 520 nm. A color change in the solution of Au NPs was observed from burgundy to purple and then to blue gray with a red shift of the absorbance...

Sensitive Colorimetric Determination of Cyromazine Using a Gold Nanoparticle (Au NP) Based Sensor with Smartphone Detection

Qiang Shi, Ting Wang, Ying Zheng, Qian Guo, Bing Wang & Sujuan Zhu
A highly sensitive colorimetric sensor based on the aggregation of gold nanoparticles (Au NPs) and a smartphone camera as detector is reported for the determination of cyromazine. In the presence of cyromazine, a decrease in the characteristic SPR absorbance peak of Au NPs is observed at 520 nm. A color change in the solution of Au NPs was observed from burgundy to purple and then to blue gray with a red shift of the absorbance...

sj-pdf-1-cpj-10.1177_00099228221134441 – Supplemental material for Electrocardiographic QTc as a Surrogate Measure of Cardiac Risk in Children, Adolescents, and Young Adults With Eating Disorders

Perry B. Dinardo, Ellen S. Rome, Ira B. Taub, Wei Liu, Kenneth Zahka & Peter F. Aziz
Supplemental material, sj-pdf-1-cpj-10.1177_00099228221134441 for Electrocardiographic QTc as a Surrogate Measure of Cardiac Risk in Children, Adolescents, and Young Adults With Eating Disorders by Perry B. Dinardo, Ellen S. Rome, Ira B. Taub, Wei Liu, Kenneth Zahka and Peter F. Aziz in Clinical Pediatrics

Supplemental Material—Feasibility assessment of solar photovoltaic deployments on building surfaces with the constraint of visual impacts

He Zheng, Bo Wu, Hui Lin, Junsong Jia & Heyi Wei
Supplemental Material for Feasibility assessment of solar photovoltaic deployments on building surfaces with the constraint of visual impacts by He Zheng, Bo Wu, Hui Lin, Junsong Jia, and Heyi Wei in Environment and Planning B: Urban Analytics and City Science.

Registration Year

  • 2022
    196

Resource Types

  • Text
    196

Affiliations

  • Guangdong Academy of Agricultural Sciences
    196
  • Wuhan University
    114
  • Central South University
    110
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    110
  • Shanghai Jiao Tong University
    107
  • Nanjing Medical University
    104
  • Tongji University
    103
  • Sun Yat-sen University
    100
  • Fudan University
    98
  • Jilin University
    97