14 Works
Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Knut Erik Tollefsen, Frédéric Alonzo, Nicholas A. Beresford, Dag Anders Brede, Elizabeth Dufourcq-Sekatcheff, Rodolphe Gilbin, Nele Horemans, Selma Hurem, Patrick Laloi, Erica Maremonti, Deborah Oughton, Olivier Simon, You Song, Michael D. Wood, Li Xie & Sandrine Frelon
Reproductive effects of ionizing radiation in organisms have been observed under laboratory and field conditions. Such assessments often rely on associations between exposure and effects, and thus lacking a detailed mechanistic understanding of causality between effects occurring at different levels of biological organization. The Adverse Outcome Pathway (AOP), a conceptual knowledge framework to capture, organize, evaluate and visualize the scientific knowledge of relevant toxicological effects, has the potential to evaluate the causal relationships between molecular,...
Adverse outcome pathways (AOPs) for radiation-induced reproductive effects in environmental species: state of science and identification of a consensus AOP network
Knut Erik Tollefsen, Frédéric Alonzo, Nicholas A. Beresford, Dag Anders Brede, Elizabeth Dufourcq-Sekatcheff, Rodolphe Gilbin, Nele Horemans, Selma Hurem, Patrick Laloi, Erica Maremonti, Deborah Oughton, Olivier Simon, You Song, Michael D. Wood, Li Xie & Sandrine Frelon
Reproductive effects of ionizing radiation in organisms have been observed under laboratory and field conditions. Such assessments often rely on associations between exposure and effects, and thus lacking a detailed mechanistic understanding of causality between effects occurring at different levels of biological organization. The Adverse Outcome Pathway (AOP), a conceptual knowledge framework to capture, organize, evaluate and visualize the scientific knowledge of relevant toxicological effects, has the potential to evaluate the causal relationships between molecular,...
Additional file 3 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 3. Trial participants’ consent form.
Additional file 5 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 5. Workwell trial: NPT constructs mapped to therapist topic guide.
Predictors and moderators of treatment outcome for single incident paediatric PTSD: a multi-centre randomized clinical trial
Carlijn de Roos, Bonne Zijlstra, Sean Perrin, Saskia van der Oord, Sacha Lucassen, Paul Emmelkamp & Ad de Jongh
Background: With few RCTs having compared active treatments for paediatric PTSD, little is known about whether or which baseline (i.e. pre-randomization) variables predict or moderate outcomes in the evaluated treatments. Objective: To identify predictors and moderators of paediatric PTSD outcomes for Eye Movement Desensitization and Reprocessing Therapy (EMDR) and Cognitive Behavioural Writing Therapy (CBWT). Method: Data were obtained as part of a multi-centre, randomized controlled trial of up to six sessions (up to 45 minutes...
Additional file 1 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 1. Workwell intervention.
Additional file 2 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 2. Trial participants’ information sheet.
Additional file 3 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 3. Trial participants’ consent form.
Additional file 5 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 5. Workwell trial: NPT constructs mapped to therapist topic guide.
Additional file 1 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 1. Workwell intervention.
Additional file 2 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 2. Trial participants’ information sheet.
Additional file 4 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 4. Workwell trial: NPT constructs mapped to participants and employer topic guide.
Additional file 4 of The Workwell trial: protocol for the process evaluation of a randomised controlled trial of job retention vocational rehabilitation for employed people with inflammatory arthritis
Alison Hammond, Kathryn A. Radford, Angela Ching, Yeliz Prior, Rachel O’Brien, Sarah Woodbridge, June Culley, Jennifer Parker & Paula Holland
Additional file 4. Workwell trial: NPT constructs mapped to participants and employer topic guide.
Predictors and moderators of treatment outcome for single incident paediatric PTSD: a multi-centre randomized clinical trial
Carlijn de Roos, Bonne Zijlstra, Sean Perrin, Saskia van der Oord, Sacha Lucassen, Paul Emmelkamp & Ad de Jongh
Background: With few RCTs having compared active treatments for paediatric PTSD, little is known about whether or which baseline (i.e. pre-randomization) variables predict or moderate outcomes in the evaluated treatments. Objective: To identify predictors and moderators of paediatric PTSD outcomes for Eye Movement Desensitization and Reprocessing Therapy (EMDR) and Cognitive Behavioural Writing Therapy (CBWT). Method: Data were obtained as part of a multi-centre, randomized controlled trial of up to six sessions (up to 45 minutes...