Allyl alkynoic esters were synthesized by the reaction of allyl amines and alkynoic acids via deaminative esterification. The reaction of allyl alkynoic esters with Pd(dba)2 and Xantphos in digylme at 110 °C for 12 h afforded the desired decarboxylated allyl alkynes in good yields.

Prostate cancer is the fifth leading cause of cancer-related deaths among males worldwide. However, the biomarker for diagnosing prostate cancer that is used currently has limitations that must be overcome. Recently, several studies have demonstrated that the cancer liquid biopsy can be implemented by using exosome miRNAs. However, the current methods for the detection of exosome miRNAs are time-consuming, expensive, and laborious. Thus, we investigated a novel method for diagnosing prostate cancer that involves the...

Background: Experiences of negative social interactions and childhood trauma (CT) can lead to aberrant hypothalamic–pituitary–adrenal functions. Poor theory of mind (ToM) ability is related to increased social stress levels; however, studies on the relationship between ToM and cortisol remain scarce. Objective: This study aimed to evaluate the relationship between ToM and the hair cortisol concentration (HCC) in healthy young adults considering the moderating role of CT. Method: A total of 206 healthy young adults were...

Additional file 1: Figure S1. CYP11A1-overexpression in HEK293 (A) and Caki-1 (B) cells. CYP11A1 was performed with green color while blue color indicated nucleus. Figure S2. Western blotting performed to determine the expression level of caspase-3,7,9 and PARP.

Background: The International Trauma Questionnaire (ITQ) is a self-report assessment focused on the core features of Post-Traumatic Stress Disorder (PTSD) and complex Post-Traumatic Stress Disorder (CPTSD). It is consistent with the organizing principles of the 11th revision to the WHO's International Classification of Diseases (ICD-11). Since the 1990s, the number of North Korean defectors (NKD) entering South Korea to escape human rights violations has been increasing rapidly, with 33,815 NKD settled by 2021. The South...

Additional file 3. (a) Blood glucose level expressed in a bar graph. (b) Plasma insulin level expressed in a bar graph. Statistical significance was set at p < 0.05; *p < 0.05, **p < 0.01, ***p < 0.001. n.s. indicates non-significant.

Additional file 4. Thickness of films prepared using 2%, 4%, and 6% CMC polymer solution (n = 10, mean ± S.E.). The thickness of films was 12.23 ± 1.20 µm, 23.05 ± 1.35 µm, and 33.14 ± 1.30 µm at 2%, 4%, and 6% CMC film concentrations, respectively.

Additional file 2: Supplementary Table S1. Clinicopathological features of patients with lung adenocarcinoma subjected to flow cytometry for comprehensive immunoprofiling. Supplementary Table S2. Clinicopathological features of patients with lung adenocarcinoma subjected to immunohistochemistry. Supplementary Table S3. Clinicopathological features of patients with lung squamous cell carcinoma subjected to immunohistochemistry. Supplementary Table S4. Clinicopathological features of patients with colon adenocarcinoma subjected to immunohistochemistry. Supplementary Table S5. Clinicopathological features of non-small cell lung cancer patients with PD-1/PD-L1 blockade...

Additional file 3: Supplementary Figure S1. Gating strategies for lymphoid and myeloid cells in lung adenocarcinoma. Supplementary Figure S2. Correlation between CD8+ T-cell infiltration and Treg infiltration in human cancer tissues. Supplementary Figure S3. Survival analysis of patients with lung SqCC according to the number of Tregs.

Additional file 3: Supplementary Figure S1. Gating strategies for lymphoid and myeloid cells in lung adenocarcinoma. Supplementary Figure S2. Correlation between CD8+ T-cell infiltration and Treg infiltration in human cancer tissues. Supplementary Figure S3. Survival analysis of patients with lung SqCC according to the number of Tregs.

Additional file 4. Supplementary Methods.

Supplemental material, sj-pdf-1-jnm-10.1177_10949968221102306 for Do Handwritten Notes Benefit Online Retailers? A Field Experiment by Sanghwa Kim, Jeonghye Choi, and Seung Hyun Kim in Journal of Interactive Marketing

Additional file 1: Table S1. Clinicohistopathologic characteristics of the tumor-free cortex and GBM tissue. Table S2. Histopathologic characteristics of GBM tissues from which TSs were derived. Figure S1. Mitochondrial stress analysis showing decreased OCR in TS13-64 following etomoxir treatment. Figure S2. The sphere-forming capacity of GBM TSs cells were examined using the Extreme Limiting Dilution Assay (ELDA). TS cells were seeded in increasing order per well (1, 5, 10, 20, and 50 cells per well)...

Additional file 1: Table S1. Clinicohistopathologic characteristics of the tumor-free cortex and GBM tissue. Table S2. Histopathologic characteristics of GBM tissues from which TSs were derived. Figure S1. Mitochondrial stress analysis showing decreased OCR in TS13-64 following etomoxir treatment. Figure S2. The sphere-forming capacity of GBM TSs cells were examined using the Extreme Limiting Dilution Assay (ELDA). TS cells were seeded in increasing order per well (1, 5, 10, 20, and 50 cells per well)...

Supplemental material, sj-pdf-1-aum-10.1177_03128962221127804 for Liquidity shocks and pension fund performance: Evidence from early access by James Brugler, Minsoo Kim and Zhuo Zhong in Australian Journal of Management

Additional file 1: Table S1. Diagnostic date for each episode of vivax malaria for 10 prospectively enrolled relapsed patients.

Additional file 1. The results of additional measurements using the conventional QA for the cases that satisfied the criteria in the conventional QA method but failed in TomoEQA.

Although dizziness is a common symptom after vaccination, the mechanism, and prognosis are not well understood. This study aimed to investigate patients with dizziness after COVID-19 vaccination by analyzing objective information. A retrospective study of patients who visited the outpatient clinics of two institutes with a complaint of dizziness occurring within 72 h after a COVID-19 vaccination. In most cases, patients experienced only a single event of dizziness, and the subjective symptom was relieved after...

Additional file 1. Table S1. Comparison of clinical, echocardiographic and CMR findings between left anterior descending coronary artery (LAD) and non-LAD territory acute myocardial infarction. Table S2. Relationship between average extracellular volume fraction of left ventricle and left atrial anatomic and functional parameters.Table S3. Differential contribution of the left atrial volume, function, and left ventricular fibrosis on the pulmonary arterial systolic pressure in reperfused acute myocardial infarction. Table S4. Relationship between pulmonary arterial systolic pressure...

Semiconductors processed at low temperature for complementary metal–oxide semiconductors (CMOS) devices are receiving considerable attention in the field of integrated electronic applications. In this work, we demonstrated a CMOS inverter constructed by n-type ZnON and p-type Te TFTs where all the processes have been done at low temperature. The electrical measurements of proposed TFTs exhibit high mobility (> 100 and > 3 cm2/Vs in case of ZnON and Te TFTs, respectively) and a stable on/off...

Supplemental material, sj-pdf-3-imr-10.1177_03000605221133655 for Prediction of homologous recombination deficiency from cancer gene expression data by Jun Kang, Jieun Lee, Ahwon Lee and Youn Soo Lee in Journal of International Medical Research

Additional file 1: Table S1. Strains and plasmids used in this study.

Additional file 2: Table S2 Primers used in this study.

Additional file 1: Fig. S1. Fluorescence spectra for a TAMRA (λex = 552 nm, λex = 578 nm) and b FAM (λex = 488 nm, λex = 512 nm).

Additional file 1. Supplementary figures: figure S1-S8