Additional file 1: Supplementary Table 1. Comparison of characteristics between maintained and decreased ipsilateral SRF in synchronous metastatic renal cell carcinoma.

Additional file 1.

Although dizziness is a common symptom after vaccination, the mechanism, and prognosis are not well understood. This study aimed to investigate patients with dizziness after COVID-19 vaccination by analyzing objective information. A retrospective study of patients who visited the outpatient clinics of two institutes with a complaint of dizziness occurring within 72 h after a COVID-19 vaccination. In most cases, patients experienced only a single event of dizziness, and the subjective symptom was relieved after...

Postoperative endophthalmitis (PE) is the devastating complication that frequently results in vision loss. Recently, enterococcus have emerged as a major cause of PE in several countries and resulted in poor visual outcome. However, the reason remains elusive. We investigate whether selection pressure of fluoroquinolone exerts effects on microorganism profiles isolated from PE. Medical records of patients who were diagnosed with PE at eight resident training institutions between January 2004 and December 2015 were reviewed. The...

Additional file 1: Table S1. Definition of covariates and outcomes. Table S2. Baseline characteristics of study patients with each mental disorder. Table S3. Sensitivity analysis. Table S4. Subgroup analysis of mental disorders. Table S5. Subgroup analysis of depression, insomnia, and anxiety.

experimental setup diagram, theory, analysis scheme, supporting data for Fig.3,4,5

experimental setup diagram, theory, analysis scheme, supporting data for Fig.3,4,5

Additional file 2: Supplementary Table 2. Raw data of microleakage analysis.

Additional file 2: Figure S1. Indicator profiles by enterotype.

Additional file 6: Figure S5. Progression-free survival by the differentially enriched microbial pathways.

Supplemental material, sj-docx-2-cll-10.1177_09636897221147920 for Fenoldopam Mesylate Enhances the Survival of Mesenchymal Stem Cells Under Oxidative Stress and Increases the Therapeutic Function in Acute Kidney Injury by Seo Yeon Jo, Hye Jin Cho and Tae Min Kim in Cell Transplantation

Unripe apples contain more functional compounds than ripe apples and thus demonstrate significant potential for use as functional food materials. In this study, the conditions for the extraction of functional compounds from unripe apples were optimized using the response surface methodology. A Box–Behnken design was used to investigate the effects of three independent variables (β-cyclodextrin concentration, extraction time, and extraction temperature) on the total polyphenol content (TPC), chlorogenic acid content (CAC), and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical...

The discovery of driver mutations is one of the key motivations for cancer genome sequencing. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we describe DriverPower, a software package that uses mutational burden and functional impact evidence to identify driver mutations in coding and non-coding sites within cancer whole genomes. Using a total of 1373 genomic features...

Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated...

The catalog of cancer driver mutations in protein-coding genes has greatly expanded in the past decade. However, non-coding cancer driver mutations are less well-characterized and only a handful of recurrent non-coding mutations, most notably TERT promoter mutations, have been reported. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancer across 38 tumor types, we perform multi-faceted pathway and network analyses of non-coding...

The catalog of cancer driver mutations in protein-coding genes has greatly expanded in the past decade. However, non-coding cancer driver mutations are less well-characterized and only a handful of recurrent non-coding mutations, most notably TERT promoter mutations, have been reported. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancer across 38 tumor types, we perform multi-faceted pathway and network analyses of non-coding...

Supplementary Material 1

Additional file 1: Figure 1. (a) viscosity at shear rate 1 s-1 for different gels with different UV exposure time; Viscosity changes with shear rate for different UV exposure time of different gels, (b) GelMA, (c) CNP + GelMA, (d) CNP (50%) GelMA, and (e) CNP GelMA. Figure 2. MTT assay with MC3T3 cells for the hydrogels and CNP samples, where control is only medium. Figure 3. Phase contrast images on Day 8 of AdMSC...

Background: Experiences of negative social interactions and childhood trauma (CT) can lead to aberrant hypothalamic–pituitary–adrenal functions. Poor theory of mind (ToM) ability is related to increased social stress levels; however, studies on the relationship between ToM and cortisol remain scarce. Objective: This study aimed to evaluate the relationship between ToM and the hair cortisol concentration (HCC) in healthy young adults considering the moderating role of CT. Method: A total of 206 healthy young adults were...

Additional file 1: Supplementary Table 1. Ingredient and content of experimental toothpastes.

Additional file 2: Supplementary Table 2. Raw data of microleakage analysis.

Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated...

Information on layer structures

Background: The objective of this study was to develop and validate machine learning models for data entry error detection in a national out-of-hospital cardiac arrest (OHCA) prehospital patient care report database. Methods: Adult OHCAs of presumed cardiac etiology were included. Data entry errors were defined as discrepancies between the coded data and the free-text note documenting the intervention or event; for example, information that was recorded as “absent” in the coded data but “present” in...

Additional file 2: Supplementary Table S1. Clinicopathological features of patients with lung adenocarcinoma subjected to flow cytometry for comprehensive immunoprofiling. Supplementary Table S2. Clinicopathological features of patients with lung adenocarcinoma subjected to immunohistochemistry. Supplementary Table S3. Clinicopathological features of patients with lung squamous cell carcinoma subjected to immunohistochemistry. Supplementary Table S4. Clinicopathological features of patients with colon adenocarcinoma subjected to immunohistochemistry. Supplementary Table S5. Clinicopathological features of non-small cell lung cancer patients with PD-1/PD-L1 blockade...