Although current guidelines didn’t support the routine use of furosemide in oliguric acute kidney injury (AKI) management, some patients may benefit from furosemide administration at an early stage. We aimed to develop an explainable machine learning (ML) model to differentiate between furosemide-responsive (FR) and furosemide-unresponsive (FU) oliguric AKI. From Medical Information Mart for Intensive Care-IV (MIMIC-IV) and eICU Collaborative Research Database (eICU-CRD), oliguric AKI patients with urine output (UO) < 0.5 ml/kg/h for the first...

Supplemental material, sj-docx-1-jom-10.1177_01492063221149676 for Not Always Helpful: Linking Intrateam Helping Types to Team Effectiveness From a Role Theory Perspective by Sang-Hoon Lee, Yihao Liu, Jaclyn Koopmann, Jee Young Seo, Le Zhou, and Yangyi Yu in Journal of Management

A new alkaloid (3), together with three known compounds, were isolated from the Thespesia populnea endophytic fungus TM-Y1-1. Their structures were elucidated by extensive spectroscopic methods. The absolute configuration of compound 3 was determined for the first time by ECD calculation and DP4+ analysis. All compounds were evaluated for antimicrobial activity. The results showed that compounds 1 and 2 both exhibited moderate inhibitory activity against banana Colletotrichum gloeosporioides with MIC value of 31.25 μg/ml.

Dolichos trilobus Linn (Leguminosae) is often used in Yi ethnic medicine to treat pain, fracture, and rheumatism. To explore the therapeutic potential of doliroside B (DB) from D. trilobus and its disodium salt (DBDS) and the underlying mechanism in pain. In the writhing test, Kunming mice were orally treated with DB and DBDS at doses of 0.31, 0.62, 1.25, 2.5, and 5 mg/kg. Vehicle, morphine, indomethacin, and acetylsalicylic acid were used as negative and positive...

Mass spectrometry (MS) has been developed for high-sensitivity structural determination of carbohydrates. Due to the similarity of oligosaccharide structures, there is still insufficient information about the correlation between carbohydrate chemical structure and mass spectra. A series of trisaccharides containing different glycosidic linkages (1→2, 1→3, 1→4, 1→6, 2→1 and 2→6), anomeric configuration (α and β), and monosaccharide (pentose, hexose and hexuronic acid), as well as two cyclodextrins (α- and β-cyclodextrin) were systematically investigated using matrix assisted...

Supplemental material, sj-docx-1-tej-10.1177_20417314221143240 for Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration by Xin Gao, Shixing Ma, Xiaotao Xing, Jian Yang, Xun Xu, Cheng Liang, Yejia Yu, Lei Liu, Li Liao and Weidong Tian in Journal of Tissue Engineering

Supplemental material, sj-docx-1-tej-10.1177_20417314221143240 for Microvessels derived from hiPSCs are a novel source for angiogenesis and tissue regeneration by Xin Gao, Shixing Ma, Xiaotao Xing, Jian Yang, Xun Xu, Cheng Liang, Yejia Yu, Lei Liu, Li Liao and Weidong Tian in Journal of Tissue Engineering

Background: Control over automatic tendencies is often compromised in challenging situations when people fall back on automatic defensive reactions, such as freeze–fight–flight responses. Stress-induced lack of control over automatic defensive responses constitutes a problem endemic to high-risk professions, such as the police. Difficulties controlling automatic defensive responses may not only impair split-second decisions under threat, but also increase the risk for and persistence of posttraumatic stress disorder (PTSD) symptoms. However, the significance of these automatic...

In cancer, the primary tumour’s organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we train a deep learning classifier to predict cancer type based on patterns of somatic passenger mutations detected in whole genome sequencing (WGS) of 2606 tumours representing 24...

In cancer, the primary tumour’s organ of origin and histopathology are the strongest determinants of its clinical behaviour, but in 3% of cases a patient presents with a metastatic tumour and no obvious primary. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, we train a deep learning classifier to predict cancer type based on patterns of somatic passenger mutations detected in whole genome sequencing (WGS) of 2606 tumours representing 24...

In this work, a microfluidic lung chip with membrane supporting cell growth that can produce multiple concentration gradients of gas and liquid is introduced. The chip is composed of a gas gradient layer in the upper part, a porous membrane supporting cell growth in the middle and a liquid gradient layer in the lower part. The gas-liquid interface environment of the cells on the membrane can expose the cells to the gas in the upper...

Supplemental Document

Supplemental Document

Supplemental Material for Accuracy of Realigned K-line for Predicting Surgical Outcomes After Laminoplasty in Patients With Degenerative Cervical Myelopathy by Qifei Duan, Guoyan Liang, Chong Chen, Yongyu Ye, Xiaoqing Zheng, Changxiang Liang and Yunbing Chang in Global Spine Journal

Supplemental Material for Accuracy of Realigned K-line for Predicting Surgical Outcomes After Laminoplasty in Patients With Degenerative Cervical Myelopathy by Qifei Duan, Guoyan Liang, Chong Chen, Yongyu Ye, Xiaoqing Zheng, Changxiang Liang and Yunbing Chang in Global Spine Journal

Appendix

Supplemental material, sj-docx-1-eso-10.1177_23969873221151142 for Sex differences in outcomes after endovascular treatment of patients with vertebrobasilar artery occlusion by Pan Zhang, Hao Li, Jinjing Wang, Feng Zhang, Lulu Xiao, Yirong Fang, Dingyi Yan, Guoqiang Xu, Chaolai Liu, Zhixin Huang, Mengmeng Gu, Hanhong Zhang and Wen Sun in European Stroke Journal

Supplementary Material

Dodecanedioic acid (DC12) is mainly prepared via microbial synthesis in industrial production, however, the refined products have many drawbacks, such as low purity, poor crystal size distribution (CSD), and heavily agglomerated character, to name a few. Therefore, the refining process is a crucial step in DC12 preparation by microbial production. In this study, a novel pneumatically agitated crystallizer for DC12 refinery by gassing crystallization was developed. A batch cooling crystallization process was developed, providing the...

Forty percent of global food production relies upon irrigation, which accounts for 70% of total global freshwater use. Thus, the mapping of cropland irrigation plays a significant role in agricultural water management and estimating food production. However, current spaceborne irrigated cropland mapping is highly reliant upon its spectral behavior, which often has high uncertainty and lacks information about the method of irrigation. Deep learning (DL) allows for the classification of irrigated cropland according to unique...

Forty percent of global food production relies upon irrigation, which accounts for 70% of total global freshwater use. Thus, the mapping of cropland irrigation plays a significant role in agricultural water management and estimating food production. However, current spaceborne irrigated cropland mapping is highly reliant upon its spectral behavior, which often has high uncertainty and lacks information about the method of irrigation. Deep learning (DL) allows for the classification of irrigated cropland according to unique...

Abstract The application of high throughput genotyping or sequencing data helps us to understand the genomic response to natural and artificial selection. In this study, we scanned the genomes of five indigenous buffalo populations belong to three recognized breeds, adapted to different geographical and agro-ecological zones in Iran, to unravel the extent of genomic diversity and to localize genomic regions and genes underwent past selection. A total of 46 river buffalo whole genomes, from West...

Herein, we prepare two types of MgAl-LDHs coatings single-doped by imidazolium ionic liquid 1-decyl-3-methylimidazolium bromide ([Demim]Br) or sodium dodecylbenzenesulphonate (SDBS) and double-doped by [Demim]Br and SDBS on AZ31B Mg alloy by using an in-situ hydrothermal treatment. Their surface morphology and corrosion resistance immersed in 3.5 wt-% NaCl solution are explored. Our results suggest that the double doping of [Demim]Br and SDBS will change the surface morphology of the coating and a uniform and dense film...

Supplemental material, sj-docx-1-jbr-10.1177_07487304221141939 for Validation of the Self-Rating of Biological Rhythm Disorder for Adolescents (SBRDA) Scale by Dim Light Melatonin Onset in Healthy Young Adults by Yang Xie, Xiaoyan Wu, Xingyue Mou, Meng Wang, Shuman Tao, Yuhui Wan and Fangbiao Tao in Journal of Biological Rhythms

Effects of strong optical feedback