Additional file 3: Table S1. Exclusion reasons for highly correlated outcomes (Random sequence). Table S2. Exclusion reasons for highly correlated outcomes (Allocation concealment). Table S3. Exclusion reasons for highly correlated outcomes (Blinding of participants/personnel). Table S4. Exclusion reasons for highly correlated outcomes (Blinding of outcome assessment). Table S5. Exclusion reasons for highly correlated outcomes (Incomplete outcome data). Table S6. Exclusion reasons for highly correlated outcomes (Selective Reporting). Table S7. Exclusion reasons for highly correlated outcomes...

Additional file 3: Table S1. Exclusion reasons for highly correlated outcomes (Random sequence). Table S2. Exclusion reasons for highly correlated outcomes (Allocation concealment). Table S3. Exclusion reasons for highly correlated outcomes (Blinding of participants/personnel). Table S4. Exclusion reasons for highly correlated outcomes (Blinding of outcome assessment). Table S5. Exclusion reasons for highly correlated outcomes (Incomplete outcome data). Table S6. Exclusion reasons for highly correlated outcomes (Selective Reporting). Table S7. Exclusion reasons for highly correlated outcomes...

Storage of energy and carbon dioxide in subsurface geological formations has been identified as key for future systems relying on renewable, zero carbon power and heat generation. All subsurface storage systems rely on the properties and integrity of the reservoir and its confining units under thermal, mechanical, hydraulic and chemical stress. These similarities enable the transfer of know-how from one type of fluid storage to another, highlighting the need for research knowledge exchange. Besides the...

This report provides an overview of the forest vegetation and the status of its conservation in Romania. Due to a large range of climates and soils, and a long-lasting postglacial vegetation history, the Romanian forests are highly diverse and species-rich ecosystems. Approximately 150 natural types of forest ecosystems have been described. Seven zonal forest formations were distinguished: (1) forest steppes and dry oak forests; (2) forests with Oriental hornbeam (Carpinus orientalis); (3) forests with oaks...

Kapitel des Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie

At their core, the UN Climate Change conferences known as “COPs” are the primary international venue for negotiating how countries should act and cooperate to avoid dangerous climate change. The 2015 Paris Agreement is its most recent notable success. Although the climate negotiations are a state government-led process, the UNFCCC (United Nations Framework Convention on Climate Change) community has increasingly recognized the need for dialogue and engagement with non-governmental stakeholders in acknowledgement of the critical...

Supplemental material, sj-docx-1-cpa-10.1177_07067437221128477 for Trends in Involuntary Psychiatric Hospitalization in British Columbia: Descriptive Analysis of Population-Based Linked Administrative Data from 2008 to 2018 by Jackson P. Loyal, M. Ruth Lavergne, Mehdi Shirmaleki, Benedikt Fischer, Ridhwana Kaoser, Jack Makolewksi and Will Small in The Canadian Journal of Psychiatry

Additional file 1. Comparative subgroup analysis. Of 66 patients, we identified 28 children with crescentic glomeruli and/or nephrotic syndrome at onset of IgAVN. Referring to the German Society of Pediatric Nephology, a corticosteroid pulse therapy only would have been recommended. Of these 28 children, 17 received corticosteroid pulse therapy per protocol, 11 did not receive any immunosuppressive therapy. We therefore performed a comparative subgroup analysis which showed similar improvements of clinical symptoms and proteinuria.

The panalpine project "DOVE" (Drilling Overdeepened Alpine Valleys), co-funded by the International Continental Scientific Drilling Program (ICDP), is drilling a series of overdeepened glacial troughs around the Alps that were formed by subglacial erosion during past glaciations. In the northeastern section of the DOVE project, we (re)investigate the inneralpine basin of Bad Aussee (Traun glacier area, Austria), the subalpine basin of the Salzach Foreland glacier (Neusillersdorf, Bavaria), and the tongue basin area of the Pleistocene...

Treatment beliefs play a crucial role for patient satisfaction and the treatment outcome in psychosomatic rehabilitation. The aim of this study was the development and the psychometric evaluation of an indication-specific questionnaire of beliefs about psychosomatic rehabilitation. The study was conducted at a psychosomatic rehabilitation clinic. The primary item list comprised k = 125 items. After a descriptive item analysis, we conducted an exploratory factor analysis. Furthermore, we tested reliability via McDonald’s Omega and construct...

Transient lysosomal damage after infection with cytosolic pathogens or silica crystals uptake results in protease leakage. Whether limited leakage of lysosomal contents into the cytosol affects the function of cytoplasmic organelles is unknown. Here, we show that sterile and non-sterile lysosomal damage triggers a cell death independent proteolytic remodelling of the mitochondrial proteome in macrophages. Mitochondrial metabolic reprogramming required leakage of lysosomal cathepsins and was independent of mitophagy, mitoproteases and proteasome degradation. In an in...

Transient lysosomal damage after infection with cytosolic pathogens or silica crystals uptake results in protease leakage. Whether limited leakage of lysosomal contents into the cytosol affects the function of cytoplasmic organelles is unknown. Here, we show that sterile and non-sterile lysosomal damage triggers a cell death independent proteolytic remodelling of the mitochondrial proteome in macrophages. Mitochondrial metabolic reprogramming required leakage of lysosomal cathepsins and was independent of mitophagy, mitoproteases and proteasome degradation. In an in...

The heterogeneity of command-and-control and market-based environmental regulations has been fully discussed. However, the classification of environmental regulations based on target-oriented approaches have not been investigated, especially the differentiated impacts on green total-factor productivity (GTFP). To bridge this gap in the literature, this study divides environmental regulations into energy-saving target (EST) regulations and emission-reduction target (ERT) regulations based on the regulation target, and compares their heterogeneous impacts on GTFP. The GTFP is measured and further...

Geoscientific questions are increasingly relevant in our daily life. However, the public awareness of geoscientific topics is very limited. Therefore, it is important to inverse the visibility of geoscientific challenges and solutions in our society. Communicating geosciences to a broader audience implies the use of innovative strategies for public outreach. We have to encourage kids to become enthusiastic about geoscientific topics already in schools and leisure activities such as museums. Besides public outreach and school...