Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney diseases worldwide. The prevalence of FSGS, relative to other glomerular disease diagnoses, seems to be increasing worldwide, and it is a major contributor to end-stage renal disease (ESRD). In 2011, McGrogan et al. reported an annual incidence rates of FSGS as 0.2 to 1.8/100, 000 population per year by reviewing literature worldwide.

Test

The Transparency and Open Promotion (TOP) Guidelines are eight modular recommendations and standards (with varying levels of stringency) for journals and funders to incentivize open science practices. TOP Factor is a transparent evaluation rubric showing the degree of a journal or funder's implementation of and compliance with TOP Guidelines. Visit cos.io/top to view the TOP Guidelines and for more resources for implementing TOP.

We are preregistering an initial study intended to start a new research program. This study will help us determine how long the designed study takes, whether stimuli and measures are well received and show reasonable inter-judge agreement, what potential effect sizes might be for questions of interest and therefore what sample sizes are suitable for the first primary study. We are documenting the basic features of the study, some research questions of interest, some hypotheses,...

This research seeks to develop a new theory of cross-group threat transfer, which conceptualizes how threats attributed to an outgroup can be transferred to other groups or to a broader social category. To test and further develop this theory, research will be conducted in the United States (U.S.) on two cases. The first case will examines the extent to which symbolic and realistic threats attributed to rioters who engaged in violence surrounding the summer 2020...

In this webinar, attendees will learn about both the technical and practical aspects of this collaborative project connecting the researcher tool OSF and the preservation system of Internet Archive. We will demonstrate how researchers can improve the openness and reproducibility of their research through preregistration, and how those preregistrations are preserved with Internet Archive. We will answer questions and seek to learn your needs and use cases for how this powerful workflow can support library...

Protocol for Scoping Review

The purpose of this project is to examine whether people's negative sentiments toward the perpetrator of a microaggression (compared to the perpetrator of a generic norm violation) extend to the entire social group that the violator belongs to. To begin we will focus on gender microaggressions, committed by men on women. We manipulate the kind of norm violation participants are exposed to (a man's microaggression or other norm violation, pretested to be of equal badness...

Open source infrastructure has paved the way for mission-aligned research stakeholders to create a united vision of interoperable tools and services that accelerate scholarly communication, fill technology gaps, converge solutions, and enable access and discoverability. Hear from a panel of research groups that have taken advantage of interoperable infrastructure to leverage more robust workflows to support rigorous, reproducible research. We also discuss the steps stakeholders and institutions can take to integrate OSF’s open API with...

The purpose of this study is to understand the psychosocial impact and mediating protective factors of social distancing measures during the COVID-19 pandemic to advance support structures for social distancing practices, guide public health recommendations, and inform mental health resource allocation and support services. This study has two specific aims, first to understand the psychological impact of social distancing measures on overall levels of mental health and second to assess the associations between psychological distress,...

Early Bilingualism and Foreign Language Learning in Secondary School

Lacrosse is one of the fastest growing sports in the United States with particular growth in popularity among younger athletes. Since 2001, total participation in lacrosse in the US has increased over 225%, and in 2015 total participation exceeded 800,000.1 Additionally, the US saw a 45.2% increase in high school sponsored programs from 2010-2018.1,2 With greater than half of US lacrosse participants under the age of fourteen, over 43,000 American collegiate athletes1, and international interest...

How does alcohol intoxication impact the gender gap in willingness to compete? To investigate this we randomly assign alcohol and placebo beverages to subjects in the lab, and then elicit their willingness to compete. Because alcohol is known to have a detrimental effect on norm obedience, our study can shed light on the contributions of social norms, in relation to innate preferences, on willingness to compete.

How does alcohol intoxication impact the perception of social norms? To investigate this, we randomly assign alcohol and placebo beverages to subjects in the lab, and then elicit their empirical and normative expectations of males’ and females’ willingness to compete. While in another study we found that alcohol intoxication, by removing gender norm, reduces gender gap in willingness to compete, this study can help to address the question of whether alcohol intoxication affects perception of...