226 Works

Autologous Peripheral Nerve Grafts to the Brain for the Treatment of Parkinson's Disease

Andrew Welleford
Parkinson’s disease (PD) is a disorder of the nervous system that causes problems with movement (motor symptoms) as well as other problems such as mood disorders, cognitive changes, sleep disorders, constipation, pain, and other non-motor symptoms. The severity of PD symptoms worsens over time as the disease progresses, and while there are treatments for the motor and some non-motor symptoms there is no known cure for PD. Thus there is a high demand for therapies...

Exploring the Role of Insulin Receptor Signaling in Hippocampal Learning and Memory, Neuronal Calcium Dysregulation, and Glucose Metabolism

Hilaree Frazier
In the late 90’s, emerging evidence revealed that the brain is insulin-sensitive, highlighted by broad expression of brain-specific insulin receptors and reports of circulating brain insulin. Contemporary literature robustly supports the role of insulin signaling in normal brain function and suggests that insulin-related processes diminish with aging, evidenced by decreased signaling markers, reduced insulin receptor density, and lower levels of insulin transport across the blood-brain barrier. In the context of pathological cognitive decline, clinical trials...

The Economic Impacts of Land Use Policies in Lexington, Kentucky

Christopher R. Bollinger, William H. Hoyt, Michael W. Clark & Xiaozhou Ding
Every five years, Lexington-Fayette Urban County Government’s Planning Commission adopts a comprehensive plan detailing goals and objectives that guide the city’s land use planning. Maintaining the city’s urban service area and preserving its rural and agricultural areas are integral parts of this plan. Within the urban service area, land is zoned to permit various types of urban uses such as residential, commercial, and industrial use. Land outside the urban service area is subject to several...

An Evaluation of How Repealing West Virginia’s Prevailing Wage Law Affected the Cost of Public Construction

Michael W. Clark & Kenneth Tester
This study compared school construction costs before and after legislative changes to prevailing wage laws in West Virginia. The study uses data provided by the School Building Authority of West Virginia (SBA). The data suggests that school construction costs increased in the years prior to the legislative changes and decreased after. Comparing projects bid with and without prevailing wages since 2013 suggests construction costs per square foot decreased by 7.3 percent since the removal of...

The Forestry Reclamation Approach

William E. Bond
The spread of surface coal mining has resulted in loss of forests in the Appalachian region. The Forestry Reclamation Approach (FRA) was developed to provide guidance for restoring forests on reclaimed mined land. This study hypothesizes that the FRA will result in larger magnitude of sediment accumulation rates in reclaimed mine sites compared to those reclaimed using grassland reclamation. Three sediment cores and six trenches were sampled within four reclaimed mined and three previously logged...

Integrating Cover Crops and Herbicides for Horseweed [Conyza canadensis (L.) Cronq.] Management Prior to Soybean [Glycine max (L.) Merr.]

Austin Sherman
Horseweed (Conyza canadensis (L.) Cronq.) is prevalent in Kentucky and can be difficult to control. Research has shown multiple weed control methods to be more sustainable than relying on chemical control alone, so the use of multiple methods for horseweed management was examined in this study. The main objective was to determine best practice(s) to reduce horseweed prior to soybean [Glycine max (L.) Merr.]. Treatments included: fall-planted cover crop [CC; cereal rye (Secale cereale L.)...

Redefining Construction As-Built Plans to Meet Current Kentucky Transportation Cabinet Needs

Victoria Lynn Lasley, Steven Waddle, Tim Taylor & Roy E., Jr. Sturgill
As-built plans have traditionally been used by construction industry practitioners to record changes made during construction. As-builts provide valuable information for new design projects as well as rehabilitation and remediation projects. The completeness and accuracy of these plans are essential for transportation industries and their success. While the importance of as-builts is widely recognized, preparing them can be difficult and time-consuming; many entities — especially public agencies — lack the resources necessary to produce accurate...

A Compromised Liver Alters PCB Toxicity and Nutrient Metabolism

Jazmyne D. L. Barney
Environmental contamination is a public health concern. In particular persistent organic pollutants like Polychlorinated Biphenyls (PCBs) have been associated with multiple chronic inflammatory diseases, including non-alcoholic fatty liver disease (NAFLD). NAFLD prevalence has steadily increased and is expected to continue to rise with an estimated 25% of the world’s population and 80-100 million people affected in the United States alone. Importantly, the liver is the primary site for endobiotic and xenobiotic metabolism, hence its proper...

Implementation and Analysis of True Lean in a Startup Company by Using PCDA Model, a Case Study in a Manufacturing Venture

Ankit Jangid
The purpose of this research is to implement and analyze the true lean transformation in a manufacturing start-up organization. Often, lean transformations are observed in developed manufacturing organizations having sophisticated production lines and numerous employees, where lean tools are utilized to reduce waste while increasing profit. However, this type of transformation is narrowly focused on quantifiable process results and falls short of the ultimate goal, establishing a true lean culture within the organization. As a...

Kentucky Traffic Accident Facts 1994 Report

KENTUCKY'S TRAFFIC ACCIDENT FACTS report for 1994 is based on accident reports submitted to the Accident Unit housed in the Kentucky State Police Information Services Branch, Records Section. As required by Kentucky Revised statutes 189.635, "every law enforcement agency whose officers investigate a vehicle accident of which a report must be made ... shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau." The stated...

Kentucky Traffic Collision Facts 2010 Report

KENTUCKY’S TRAFFIC COLLISION FACTS report for 2010 is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised Statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize data on traffic...

AID Project Summary Report for Intelligent Compaction

David Q. Hunsucker, Kean H., Jr. Ashurst & Brad W. Rister
This study reviews data from five roadway construction projects on which intelligent compaction (IC) techniques were used to achieve the more uniform compaction of road-building materials. Kentucky Transportation Center (KTC) researchers looked at IC data collected from these projects — resulting in the production of eight analyzable data sets — to determine whether they complied with the special construction note included in contract documents. The report also compares the intelligent compaction measurement value (ICMV) collected...

Wage Disparity in the Accounting Profession and Information Quality

Russell Williamson
Does wage disparity, measured as the difference between highest and lowest paid workers, affect the quality of reported financial information? I collect accounting professional wage data from an international accounting and finance employment placement firm for the period of 1972 to 2017. I investigate to what degree wage disparity in corporate and public accounting has affected accounting information quality by testing predictions derived from equity theory and tournament theory. I find that vertical wage disparity...

Spatial Augmented Reality Using Structured Light Illumination

Ying Yu
Spatial augmented reality is a particular kind of augmented reality technique that uses projector to blend the real objects with virtual contents. Coincidentally, as a means of 3D shape measurement, structured light illumination makes use of projector as part of its system as well. It uses the projector to generate important clues to establish the correspondence between the 2D image coordinate system and the 3D world coordinate system. So it is appealing to build a...

Caregivers of Parents with Alzheimer's Disease

Matthew Cornu
This study furthers Alzheimer’s family literature regarding the impact of caregiver attachment, readiness to provide care, and caregiver quality of life. A sample of 33 participants caring for a parent with Alzheimer’s disease in the state of Kentucky was recruited to complete a questionnaire for the study. The questionnaire consisted of an online survey about participants’ experiences and attachments growing up with their parents, their experiences becoming caregivers to their parents with Alzheimer’s disease, and...

Modeling Daily Posttraumatic Stress Symptoms and Mental Contamination Experiences Among Survivors of Sexual Trauma

Alex Brake
Mental contamination (i.e., feelings of dirtiness in the absence of contact with a contaminant) is a potentially important yet understudied factor in posttraumatic psychopathology, particularly for survivors of sexual trauma. Mental contamination has been linked to PTSD symptom severity, negative affect, and coping cross-sectionally and in lab-based paradigms, but research has yet to assess these relationships in ecological contexts. The present study extends previous cross-sectional findings by modelling relationships between mental contamination and posttraumatic psychopathology,...

Major Lower Paleozoic Horizons of the Southern Illinois Basin

John B. Hickman
The geology exposed at the surface in the southern Illinois Basin has been mapped in great detail by countless workers over the past century. With the exception of limited and scattered exposures in incised river valleys, the oldest rocks exposed outside of the Jessamine, Nashville, and Ozark Domes surrounding the Illinois Basin are Mississippian in age. Extensive deposits of Cambrian–Devonian sediments occur in the subsurface above crystalline basement in this region, however. All available data...

Pilot Study of Text Message Nudges as a Way to Improve Weight Loss Outcomes

Madison Copher
Weight loss programs for women are on the rise, including both face to face and online programs. However, current research is limited on the process measures and content which produce adherence and the largest outcomes. With obesity on the rise in the United States, it is important to understand out health coaches can strengthen their programs to better support the obese population in their weight loss journey. The purpose of this pilot study was to...

An Inverse Eigenvalue Problem for the Schrödinger Equation on the Unit Ball of R3

Maryam Ali Al Ghafli
The inverse eigenvalue problem for a given operator is to determine the coefficients by using knowledge of its eigenfunctions and eigenvalues. These are determined by the behavior of the solutions on the domain boundaries. In our problem, the Schrödinger operator acting on functions defined on the unit ball of $\mathbb{R}^3$ has a radial potential taken from $L^2_{\mathbb{R}}[0,1].$ Hence the set of the eigenvalues of this problem is the union of the eigenvalues of infinitely many...

\"I've Known Rivers\"

Catherine Gooch
My dissertation, titled “I’ve Known Rivers”: Representations of the Mississippi River in African American Literature and Culture, uncovers the impact of the Mississippi River as a powerful, recurring geographical feature in twentieth-century African American literature that conveys the consequences of capitalist expansion on the individual and communal lives of Black Americans. Recent scholarship on the Mississippi River theorizes the relationship between capitalism, geography, and slavery. Walter Johnson’s River of Dark Dreams: Slavery and Empire in...

Online Language Acquisition and Leadership in Higher Education-Governed Intensive English Programs

Brandon Decker
Research has indicated accredited, U.S. higher education-governed intensive English programs (IEPs) often struggle financially due to a scarcity of resources (namely students) because of political and global economic factors and increased competition (ICEF Monitor, 2017; IIE, 2017; Ladika, 2018; Soppelsa, 2015). However, few IEPs advertise online language acquisition (OLA) courses despite the increase in online study methods at the higher education institutes governing the programs and its use by competitors. The purpose of this study...


Michael Dalessio
A multitude of higher education institutions have adopted comprehensive smoke- and tobacco-free policies to minimize tobacco use, increase quit attempts, and reduce exposure to secondhand smoke on campus. However, the majority of campuses across the U.S. still have non-comprehensive policies and/or designated tobacco use areas. Given the limited research in this area, the purpose of this dissertation was to assess the attitudes, perceptions, tobacco use behaviors, and actual observational compliance of students, faculty, and staff...

Beyond Telling

Jane Samuel
Despite calls for increased Adoption Communication Openness (ACO) within the adoptive family, research indicates that families still struggle to accomplish the recommended elements and levels of openness. What could be holding families back from this key process? Three focus groups comprised of 17 adoptive parents of early adolescents (aged 10-14) who were age 0-2 at the time of placement were thematically coded. This inductive analysis revealed the complexity rooted in being —sometimes successfully and sometimes...

Investigating the Use of In-Place Lateral Pull Off Tests to Determine the Compressive Strength of Structural Concrete

Charlie Sun
The Kentucky Transportation Cabinet’s current practice for determining the compressive strength of structural concrete consists of two methods. Both methods require that samples be delivered to an off-site facility for testing. Accordingly, affected parties on the project site must wait for the delivery of samples to the off-site facility, the performance of tests and analysis of test data, and the return of test results to the project site. Analysis of existing structural concrete requires core...

Reducing Construction Costs Through Effective Field Communication and Administration

Gabriel B. Dadi, Roy E., Jr. Sturgill, Steven Waddle & Steven Douglas Kreis
Falling Road Fund receipts have placed added strain on the Kentucky Transportation Cabinet’s (KYTC) already-underfunded highway program. Revenue declines have increased the urgency of improving the efficiency and cost-effectiveness of the Cabinet’s operations. One method KYTC can use to realize greater cost savings is improving the administration of construction projects. Effective field communication and administration helps control construction costs, enhances quality, and minimizes delays and claims. One challenge the Cabinet will need to confront to...

Registration Year

  • 2019

Resource Types

  • Text


  • University of Kentucky
  • Iowa State University