Supplementary Material 1

Supplemental material, sj-pdf-1-imr-10.1177_03000605221132711 for New onset atrial fibrillation during orthotopic liver transplantation induced by iced saline injection for transpulmonary thermodilution: a case report by Xin Li, Xu Wang and Zheng Guan in Journal of International Medical Research

Additional file 1: Development of AI-based automatic CAC on chest CT.

Additional file 5: Fig. S8. Co-localization of HCR with centrin1 and PCM1. HeLa cells transfected with HCR-GFP were co-stain with centrin1 (red) and gamma-tubulin (cyan) and DAPI (blue) or PCM1 (red) and gamma-tubulin (cyan) and DAPI (blue); scale bars, 10 μm. Fig. S9. HCR interacts with CEP131. HeLa cell lysates were immunoprecipitated with antibodies specific for HCR, astrin, or negative control rabbit IgG. The precipitates were analyzed by immunoblotting with antibodies against HCR and CEP131....

Additional file 8. Verification reports of HCR-KO cell line.

Additional file 1: Supplemental Table 1. Comparison of baseline characteristics between survivors and non-survivors. Supplemental Figure 1. Kaplan-Meier plots for cumulative 1-year survival according to early coagulopathy. The difference was statistically significant according to the log-rank test (P <0.001).

Supplemental Material for Longitudinal Relationship Between Frailty and Cognitive Impairment in Chinese Older Adults: A Prospective Study by Xinxin Zhao, Qi Chen, Liang Zheng, Longbing. Ren, Yinghong Zhai, Jue Li, and Jia He in Journal of Applied Gerontology

A phytochemical investigation of Bidens procera L.C.Xu ex X.W.Zheng afforded two novel polyacetylenes, tridecane-2E-monoene-4,6,8-triyntylen-1,13-diol-12-O-β-glucoside (1) and tetradecane-2E,8E-diene-4,6-diyne-1,14-diol-13-O-β-glucoside (2), together with ten known compounds (3 − 12). Their chemical structures were elucidated by NMR and MS spectrums as well as the comparison of the published data. Furthermore, the chemotaxonomy of the yielded compounds was also discussed.

Additional file 1.

Arsenic has been identified as a carcinogen, although the molecular mechanism underlying itscarcinogenesis has not been fully elucidated. To date, only a few studies have attempted to confirm a direct link between oxidative stress and the Warburg effect . This study demonstrated that 0.2 μmol/L As3+ induced the Warburg effect to contribute to abnormal proliferation of L-02 cells, that was mediated by upregulation of hexokinase 2 (HK2), a key enzyme in glycolysis. Further study indicated...

Additional file 7: Fig. S1. a-b Violin plots showing GSVA score of cSE (a) or tSE (b) signature genes in four MB subgroups or NC of the indicated MB datasets. (c-d) Kaplan-Meier survival analysis of the GSVA scores of cSE (c) or tSE (d) genes in Cavalli dataset of MB. The patient cohort was stratified as high versus low groups by median GSVA score. Statistical significance was determined by one-way ANOVA (a-b), two-sided log-rank test...

Additional file 1: Figure S1. (A) The transfection efficiencies of sheL31-1 and sheL31-2 in HCT 116 cells were detected by qRT-PCR. (B) The transfection efficiencies of sheL31-1 and sheL31-2 in HCT 116 and RKO cells were evaluated through observing the fluorescence inside cells. Magnification times: 200×. (C) The densitometric analyses of Akt, P-Akt, CCND1, CDK6 and PIK3CA proteins expression. * P < 0.05, *** P < 0.001. Figure S2. (A) The volcano plot of gene...

Additional file 1: Figure S1. Study design. Figure S2. Tumor response of patients in the dose-escalation and dose-expansion phase. Figure S3. Percentage change from baseline in target lesion tumour burden over time in patients with select tumors at the recommended dose (30 mg/kg q3w). Figure S4. Receiver operating characteristic curve analysis of pSmad2 level in tumor cells for ORR per RECIST v1.1. Table S1. Pharmacokinetic parameters following a single infusion. Table S2. Summary of treatment-related...

Additional file 1: Cost estimates for the rest of the first year or in post-CVD phase. Table S1. Lifetime cost-effectiveness results for each subgroup. Table S2. Baseline characteristics of the study participants. Table S3. Unit prices of drugs. Table S4. Costs of each treatment procedure. Table S5. Hazard ratios and parameters for scale and shape of the subgroup analysis.

Additional file 2.

Additional file 2.

Supplementary Material 5

Supplementary Material 7

Additional file 4. Summary of the subgroup analyses of the correlation between circulating irisin levels and HOMA-IR.

Additional file 5. Summary of the subgroup analyses of the correlation between circulating irisin levels and BMI.

Additional file 4: Supplemental Table S4. Primers used for qRT- PCR

Purpose: Understanding the mechanism of brain functional alterations in rectal cancer (RC) patients is of great significance to improve the prognosis and quality of life of patients. Additionally, the influence of chemotherapy on brain function in RC patients is still unclear. In this study, we aimed to investigate the alterations of brain functional network dynamics in RC patients and explore the effects of chemotherapy on temporal dynamics of dynamic functional connectivity (DFC). Methods: The group...

Additional file 1: Supplementary Fig. 1. (A) RT-qPCR analyses of FOXD1 mRNA in the indicated breast tumor cell lines and MCF-10A. Error bars, SEM. n = 3. (B) Western blotting analyses of FOXD1 expression in the indicated breast tumor cell lines and MCF-10A. (C)RT-qPCR analysis of FOXD1 expression in control and sh-FOXD1 cells (MDA231 and MDA468), or control and FOXD1 overexpression cells (MCF-7). Error bars, SEM. n = 3. **p < 0.01, ***p<0.001 by Student’s...

Additional file 2. Predicted binding sites through JASPAR database, and the sequences of the constructed Luciferase activity reporter assays.

Additional file 1: Supplementary figures.