1,140 Works

sj-pdf-1-jcb-10.1177_0271678X221113897 - Supplemental material for Neuronal Serpina3n is an endogenous protector against blood brain barrier damage following cerebral ischemic stroke

Fengshi Li, Yueman Zhang, Ruqi Li, Yan Li, Shenghao Ding, Jianpo Zhou, Tianchen Huang, Chen Chen, Bingwei Lu, Weifeng Yu, Johannes Boltze, Peiying Li & Jieqing Wan
Supplemental material, sj-pdf-1-jcb-10.1177_0271678X221113897 for Neuronal Serpina3n is an endogenous protector against blood brain barrier damage following cerebral ischemic stroke by Fengshi Li, Yueman Zhang, Ruqi Li, Yan Li, Shenghao Ding, Jianpo Zhou, Tianchen Huang, Chen Chen, Bingwei Lu, Weifeng Yu, Johannes Boltze, Peiying Li, Jieqing Wan in Journal of Cerebral Blood Flow & Metabolism

Additional file 1 of LncRNA CEBPA-DT promotes liver cancer metastasis through DDR2/β-catenin activation via interacting with hnRNPC

Yunshi Cai, Tao Lyu, Hui Li, Chang Liu, Kunlin Xie, Lin Xu, Wei Li, Hu Liu, Jiang Zhu, Yinghao Lyu, Xuping Feng, Tian Lan, Jiayin Yang & Hong Wu
Additional file 1: Table S1. Clinical baseline characteristics of 101 patients with HCC according to CEBPA-DT expression level. Table S2. Prognostic factors for overall survival and recurrence-free survival by the univariate Cox proportional hazards regression model. Table S3. Independent prognostic factors for overall survival and recurrence-free survival by the multivariate Cox proportional hazards regression model. Table S4. The antibodies used in this study. Table S5. Sequence of primers used for PCR in this study. Table...

Supplementary document for Photonics Millimeter Wave Bidirectional Full-duplex Communication based on Polarization Multiplexing - 6107133.pdf

Weiping Li, Jianjun Yu, Feng Wang, Xiaoxue Ji, Yang Xiongwei, Tianqi Zheng, Qihang Wang, Wen Zhou, Jianguo Yu & Feng Zhao
should be removed

Supplementary document for Photonics Millimeter Wave Bidirectional Full-duplex Communication based on Polarization Multiplexing - 6107133.pdf

Weiping Li, Jianjun Yu, Feng Wang, Xiaoxue Ji, Yang Xiongwei, Tianqi Zheng, Qihang Wang, Wen Zhou, Jianguo Yu & Feng Zhao
should be removed

Superior strength–ductility combination in Al alloys via dislocation gradient structure

Feng Wang, Yue Li, Xinren Chen, Huan Zhao, Khurram Yaqoob, Yong Du, Zhangwei Wang & Min Song
The precipitation hardening is widely applied to strengthen Al alloys. Here, we report an alternative way to achieve high-strength Al alloys via forming the dislocation gradient through pre-torsion. Remarkably, the gradient Al alloys exhibit a sharp increase in ultimate tensile strength up to 605 MPa yet nearly without reducing the uniform elongation, thereby outperforming their counterparts. The superior strength–ductility combination is ascribed to the excellent strengthening and strain hardening effects stemming from the substantial hetero-deformation-induced...

Exploiting lactic acid bacteria for colorectal cancer: a recent update

Yang Chen, Bo Yang, Jianxin Zhao, R. Paul Ross, Catherine Stanton, Hao Zhang & Wei Chen
Colorectal cancer (CRC) is the third most common cancer in the world. Currently, chemotherapy and radiotherapy used to treat CRC exhibit many side effects, hence, it is an urgent need to design effective therapies to prevent and treat CRC. Lactic acid bacteria (LAB) can regulate gut microbiota, intestinal immunity, and intestinal mechanical barrier, which is becoming a hot product for the prevention and treatment of CRC, whereas comprehensive reviews of their anti-CRC mechanisms are limited....

Fluorine Added to Lead the Way to Future Energetic Materials: 3,5-difluoro-2,4,6-trinitroaniline

Cong Li, Mingwei Liu, Taotao Li, Linjian Wang, Rui Zhang & Suming Jing
The efficient design and synthesis of energetic compounds with the highest possible energy and chemical stability has attracted enormous attention due to their high-tech applications. Here we show an energetic compound, 3,5-difluoro-2,4,6-trinitroaniline (8), the relationship between structure and properties is discussed based on the single-crystal diffraction data and several theoretical techniques. It exhibits exceptionally outstanding combination properties, high density (1.861 g cm−3 at 273 K), poor water solubility, high thermal stability (Td = 243°C), superior...

Additional file 21 of Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma

Yexin Tong, Mingjun Sun, Lingli Chen, Yunzhi Wang, Yan Li, Lingling Li, Xuan Zhang, Yumeng Cai, Jingbo Qie, Yanrui Pang, Ziyan Xu, Jiangyan Zhao, Xiaolei Zhang, Yang Liu, Sha Tian, Zhaoyu Qin, Jinwen Feng, Fan Zhang, Jiajun Zhu, Yifan Xu, Wenhui Lou, Yuan Ji, Jianyuan Zhao, Fuchu He, Yingyong Hou … & Chen Ding
Additional file 21: Fig. S21. Protein expression changes in PANC-1 cell lines after HOGA1 knocked down and over expressed, related to Fig. 8. A The schematic work flow of validation experiments for the protein expression changes after HOGA1 knocked down and over expressed. B The volcano plot showing the proteins that significantly altered between PANC-1 cells with HOGA1 KD (left)/HOGA1 OE (right) and WT. The GO processes enriched by proteins upregulated in HOGA1 KD cell...

Regulation mechanism for the formation and microwave absorbing performance of CNT/CoFe-MOF derived hierarchical composite

Jinxiao Wang, Jianfeng Yang & Jun Yang
The structure design, performance analysis, and process optimization of CNT/MOF-derived hierarchical composite play an important role in the development of high-performance microwave absorbing materials. Herein, the preparation, morphology evolution, and electromagnetic wave absorption mechanism of CNT/MOF-derived hierarchical composite were systematically investigated. The regulation mechanism was revealed by studying the changes in the morphological characteristics, electromagnetic properties, and microwave absorbing performance of CNT/MOF-derived hierarchical composite under different process parameters. The results show that the morphological characteristics...

Specific associations between fungi and bacteria in broncho-alveolar aspirates from mechanically ventilated intensive care unit patients

Arezoo Shajiei, Lei Liu, Jolien Seinen, Willem Dieperink, Sven Hammerschmidt, Jan Maarten van Dijl & Hermie J.M. Harmsen
The detection of fungi in the human respiratory tract may represent contamination, colonization or a respiratory infection. To develop effective management strategies, a more accurate and comprehensive understanding of the lung fungal microbiome is required. Therefore, the objective of the present study was to define the “mycobiome” of mechanically ventilated patients admitted to an intensive care unit (ICU) using broncho-alveolar aspirate (“sputum”) samples and correlate this with clinical parameters and the bacterial microbiota. To this...

A. caviae infection triggers IL-1β secretion through activating NLRP3 inflammasome mediated by NF-κB signaling pathway partly in a TLR2 dependent manner

Qiankun Yang, Jianguo Zhang, Feixue Liu, Huizhen Chen, Wei Zhang, Haitao Yang, Nana He, Jingquan Dong & Panpan Zhao
Aeromonas caviae, an important food-borne pathogen, induces serious invasive infections and inflammation. The pro-inflammatory IL-1β functions against pathogenic infections and is elevated in various Aeromonas infection cases. However, the molecular mechanism of A. caviae-mediated IL-1β secretion remains unknown. In this study, mouse macrophages (PMs) were used to establish A. caviae infection model and multiple strategies were utilized to explore the mechanism of IL-1β secretion. IL-1β was elevated in A. caviae infected murine serum, PMs lysates...

Nepetin reduces virulence factors expression by targeting ClpP against MRSA-induced pneumonia infection

Shisong Jing, Xinran Ren, Li Wang, Xiangri Kong, Xingye Wang, Xiren Chang, Xuerui Guo, Yan Shi, Jiyu Guan, Tiedong Wang, Bingmei Wang, Wu Song & Yicheng Zhao
The resistance of Staphylococcus aureus (S. aureus) to various antibiotics has increased dramatically due to the misuse of antibiotics, and thus the development of new anti-infective drugs with new targets is urgently needed to combat resistance. Caseinolytic peptidase P is a case in hydrolase that regulates the virulence level of S. aureus. Here, we found that nepetin, a small-molecule compound from traditional Chinese herbal flavonoids, effectively inhibits ClpP activity. Nepetin suppressed the virulence of S....

Measuring Physical Disorder in Urban Street Spaces: A Large-Scale Analysis Using Street View Images and Deep Learning

Jingjia Chen, Long Chen, Yan Li, Wenjia Zhang & Ying Long
Physical disorder is associated with negative outcomes in economic performance, public health, and social stability, such as the depreciation of property, mental stress, fear, and crime. A limited but growing body of literature considers physical disorder in urban space, especially the topic of identifying physical disorder at a fine scale. There is currently no effective and replicable way of measuring physical disorder at a fine scale for a large area with low cost, however. To...

An Optimal Hybrid Approach to Calculate Conditional Power

Jian Zhu, Xin Li & Yi Liu
When used in clinical trial adaptive designs, conditional power (CP) is most commonly calculated assuming the current trend, but this approach has been criticized for substantially deviating from the actual CP due to “double-dipping” the interim data (i.e., using the interim data as part of the final analysis test statistic and as the assumption for the remainder of the trial). By contrast, CP assuming the design assumption preserves the shape of the CP curve by...

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part II: OCD and PTSD

Borwin Bandelow, Christer Allgulander, David S. Baldwin, Daniel Lucas da Conceição Costa, Damiaan Denys, Nesrin Dilbaz, Katharina Domschke, Eric Hollander, Siegfried Kasper, Hans-Jürgen Möller, Elias Eriksson, Naomi A. Fineberg, Josef Hättenschwiler, Hisanobu Kaiya, Tatiana Karavaeva, Martin A. Katzman, Yong-Ku Kim, Takeshi Inoue, Leslie Lim, Vasilios Masdrakis, José M. Menchón, Euripedes C. Miguel, Antônio E. Nardi, Stefano Pallanti, Giampaolo Perna … & Joseph Zohar
This is the third version of the guideline of the World Federation of Societies of Biological Psychiatry (WFSBP) Task Force for the Pharmacological Treatment of Anxiety, Obsessive–Compulsive and Posttraumatic Stress Disorders which was published in 2002 and revised in 2008. A consensus panel of 34 international experts representing 22 countries developed recommendations based on efficacy and acceptability of the treatments. In this version, not only medications but also psychotherapies and other non-pharmacological interventions were evaluated,...

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part I: Anxiety disorders

Borwin Bandelow, Christer Allgulander, David S. Baldwin, Daniel Lucas da Conceição Costa, Damiaan Denys, Nesrin Dilbaz, Katharina Domschke, Elias Eriksson, Naomi A. Fineberg, Josef Hättenschwiler, Eric Hollander, Hisanobu Kaiya, Tatiana Karavaeva, Siegfried Kasper, Martin Katzman, Yong-Ku Kim, Takeshi Inoue, Leslie Lim, Vasilios Masdrakis, José M. Menchón, Euripedes C. Miguel, Hans-Jürgen Möller, Antonio E. Nardi, Stefano Pallanti, Giampaolo Perna … & Joseph Zohar
This is the third version of the guideline of the World Federation of Societies of Biological Psychiatry (WFSBP) Task Force for the Pharmacological Treatment of Anxiety, Obsessive–Compulsive and Posttraumatic Stress Disorders (published in 2002, revised in 2008). A consensus panel of 33 international experts representing 22 countries developed recommendations based on efficacy and acceptability of available treatments. In total, 1007 RCTs for the treatment of these disorders in adults, adolescents, and children with medications, psychotherapy...

World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders – Version 3. Part I: Anxiety disorders

Borwin Bandelow, Christer Allgulander, David S. Baldwin, Daniel Lucas da Conceição Costa, Damiaan Denys, Nesrin Dilbaz, Katharina Domschke, Elias Eriksson, Naomi A. Fineberg, Josef Hättenschwiler, Eric Hollander, Hisanobu Kaiya, Tatiana Karavaeva, Siegfried Kasper, Martin Katzman, Yong-Ku Kim, Takeshi Inoue, Leslie Lim, Vasilios Masdrakis, José M. Menchón, Euripedes C. Miguel, Hans-Jürgen Möller, Antonio E. Nardi, Stefano Pallanti, Giampaolo Perna … & Joseph Zohar
This is the third version of the guideline of the World Federation of Societies of Biological Psychiatry (WFSBP) Task Force for the Pharmacological Treatment of Anxiety, Obsessive–Compulsive and Posttraumatic Stress Disorders (published in 2002, revised in 2008). A consensus panel of 33 international experts representing 22 countries developed recommendations based on efficacy and acceptability of available treatments. In total, 1007 RCTs for the treatment of these disorders in adults, adolescents, and children with medications, psychotherapy...

sj-doc-2-tct-10.1177_15330338221123634 - Supplemental material for Ixazomib Combined With Autologous Stem Cell Transplantation for POEMS Syndrome: A Case Report and Meta-Analysis

Ji Ma, Xiaoyue Wang, Hui Lu, Zhihao Liang & Liang Wang
Supplemental material, sj-doc-2-tct-10.1177_15330338221123634 for Ixazomib Combined With Autologous Stem Cell Transplantation for POEMS Syndrome: A Case Report and Meta-Analysis by Ji Ma, Xiaoyue Wang, Hui Lu, Zhihao Liang and Liang Wang in Technology in Cancer Research & Treatment

Preventive effect of isostrictiniin from Nymphaea candida on carbon tetrachloride-induced hepatic fibrosis in mice

Hui juan Dong, Yuxuan Guo, Tao Liu & Jun Zhao
This study aimed to investigate the preventive effect of isostrictiniin (ISO) from Nymphaea candida against CCl4-induced hepatic fibrosis (HF) in mice. HF in mice was induced by intraperitoneally injecting 10% CCl4 olive oil solution twice a week. After intragastric administration for 8 weeks. ISO (25, 50, or 100 mg/kg) could significantly reduce the serum AST, ALT, ALP, HA, LN, PC-III, C-IV, IL-1β, and TNF-α levels in HF mice, and the collagen fiber deposition in ISO...

A high-dimensional neural network potential for molecular dynamics simulations of condensed phase nickel and phase transitions

Hao Deng, Jeffrey Comer & Bin Liu
A high-dimensional neural network interatomic potential was developed and used in molecular dynamics simulations of condensed phase Ni and Ni systems with liquid–solid phase coexistence. The reference data set was generated by sampling the potential energy surface over a broad temperature-pressure domain using ab initio MD simulations to train a unified potential. Excellent agreement was achieved between bulk face-centred cubic nickel thermal expansion simulations and relevant experimental data. The same potential also yields accurate structures...

Interactive Effects Panel Data Models with General Factors and Regressors

Bin Peng, Liangjun Su, Joakim Westerlund & Yanrong Yang
This paper considers a model with general regressors and unobservable factors. An estimator based on iterated principal components is proposed, which is shown to be not only asymptotically normal and oracle efficient, but under certain conditions also free of the otherwise so common asymptotic incidental parameters bias. Interestingly, the conditions required to achieve unbiasedness become weaker the stronger the trends in the factors, and if the trending is strong enough unbiasedness comes at no cost...

Supplemental Material—Geographical detector-based assessment of multi-level explanatory powers of determinants on China’s medical-service resumption during the COVID-19 epidemic

Bisong Hu, Sumeng Fu, Jin Luo, Hui Lin, Qian Yin, Vincent Tao, Bin Jiang, Lijun Zuo & Yu Meng
Supplemental Material for Geographical detector-based assessment of multi-level explanatory powers of determinants on China’s medical-service resumption during the COVID-19 epidemic by Bisong Hu, Sumeng Fu, and Jin Luo and Hui Lin, Qian Yin, Vincent Tao, Bin Jiang, Lijun Zuo, and Yu Meng in Environment and planning B: Urban analytics and city science

Additional file 1 of Spatial metabolomics on liver cirrhosis to hepatocellular carcinoma progression

Michelle Junyi He, Wenjun Pu, Xi Wang, Xiaoni Zhong, Dong Zhao, Zhipeng Zeng, Wanxia Cai, Jiayi Liu, Jianrong Huang, Donge Tang & Yong Dai
Additional file 1: Figure S1. Total metabolite distributions in the HC, LC and HCC tissue samples. a HE and MSI diagrams of HC, LC and HCC whole samples under the negative ionization mode. b PLS-DA comparison of AFADESI-MSI data under the negative ionization mode. c, d Alterations of metabolites detected by AFADESI-MSI method in the HC, LC and HCC samples based on positive (c) and negative (d) ionization modes. e, f K-means diagrams of the...

Additional file 1 of Temporal regulation of notch activation improves arteriovenous fistula maturation

Qunying Guo, Guang Chen, Hunter Cheng, Ying Qing, Luan Truong, Quan Ma, Yun Wang & Jizhong Cheng
Additional file 1: Fig. S1. Photograph of the common carotid artery and AVF after surgery. A. Right common carotid artery in normal mice. B. This picture shows the anastomosis of common carotid artery with internal jugular vein in AVF after surgery. The yellow arrow points to the sutures. The inflated jugular vein indicates the patency of the AVF. Scale bars = 1 mm. Fig. S2. Notch signaling conducts signals between neighboring cells. There are 5...

Supplemental Material - Epidemiological and clinical characteristics of vaccinated COVID-19 patients: A meta-analysis and systematic review

Wen Tian, Xingxiang Ren, Mei Han, Yuanyuan Zhang, Xu Gao, Zhihai Chen & Wei Zhang
Supplemental Material for Epidemiological and clinical characteristics of vaccinated COVID-19 patients: A meta-analysis and systematic review by Wen Tian, Xingxiang Ren, Mei Han, Yuanyuan Zhang, Xu Gao, Zhihai Chen, and Wei Zhang in International Journal of Immunopathology and Pharmacology

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  • 2022
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  • Jinan University
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  • Chinese Academy of Medical Sciences & Peking Union Medical College
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  • Sichuan University
    763
  • Fudan University
    754
  • Shanghai Jiao Tong University
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  • Sun Yat-sen University
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  • Zhejiang University
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  • Huazhong University of Science and Technology
    610
  • Chinese Academy of Sciences
    572
  • Nanjing Medical University
    558