A method for the preparation of primary amides from nitriles using hydrogen peroxide and a catalytic amount of sodium molybdate in ethanol is described. Using this method, nitriles including aromatic nitriles, aromatic heterocyclic nitriles and aliphatic nitriles were converted into the corresponding amides in moderate to high yields. Electronic and steric effects of substituent have a significant effect on the reactivity of nitrile, nitriles with electron-withdrawing group at the para or meta position show high...

In order to the improvement of steel quality and dephosphorization capacity, it is vital to realize the microscopic essence of dephosphorization reaction of the slags. In this work, the temperature dependence of phosphorus distribution ratio and phosphate capacity is discussed with respect to the structure characterized by Raman and MAS-NMR. As the temperature increases from 1550°C to 1600°C, the reduction of Q0(Si) and Q0(P) weakens the formation of the Si–O–Ca–O–P linkages that can stabilize the...

Juglans mandshurica Maxim., 1856 is a second-class, protected, rare tree species of high economic and ecological value. We elucidated the complete mitochondrial (mt) genome of J. mandshurica using the Illumina Novaseq 6000 and Nanopore platforms. The complete sequences of 558,032 and 161,386 bp had an overall GC content of 45.0% and 45.3%, respectively, and 61 genes could be annotated, including 38 protein-coding, 20 tRNA, and 3 rRNA genes. The high-quality J. mandshurica mt genomic sequences...

Supplemental material, sj-docx-1-oed-10.1177_25158414221139002 for A medication-wide association study to identify medications associated with incident clinically significant diabetic retinopathy by Ruilin Xiong, Wei Wang, Xianwen Shang, Yixiong Yuan, Yifan Chen, Lei Zhang, Katerina V Kiburg, Zhuoting Zhu and Mingguang He in Therapeutic Advances in Ophthalmology

Supplementary Material

In present, there was no detailed report on the formulation optimization and quality evaluation of aprepitant (APT) injectable lipid emulsion (APT-IE). The aim of the present investigation was to prepare and evaluate its properties of APT-IE loaded with an APT phospholipid complex (APT-PC) in vitro and in vivo. APT-PC was obtained by solvent evaporation with APT and phospholipids, then analyzed by X-ray diffraction, Fourier transform infrared spectroscopy and differential scanning calorimetry. Lipid emulsions are a...

The discrimination and determination of small organics may be employed for baijiu identification. A single nanoparticle was designed as a fluorescence sensor to address this issue. Via specific host-guest interactions, small organics may significantly disrupt the energy transmission of nanoparticles, resulting in sharp changes in characteristic fluorescence peaks, thus allowing the discrimination of single substances or mixtures by principal component analysis (PCA), hierarchical clustering analysis (HCA), and linear discriminant analysis (LDA). The system was characterized...

Left ventricular hypertrophy is associated with adverse outcomes among peritoneal dialysis patients. The aim of this study was to evaluate the prognostic impact of baseline left ventricular hypertrophy and its relationship with baseline peritoneal transfer characteristics in peritoneal dialysis patients. We enrolled 151 incident peritoneal dialysis patients to perform a multicentric retrospective cohort study since January 1, 2017 to January 31, 2021. Patients were grouped based on baseline dialysate-to-plasma creatinine ratio at 4 h as...

Some equations about the construction of the diffuser sheet model

Supplemental material, sj-docx-1-jaf-10.1177_0148558X221148626 for Measuring Disaggregation Quality by Ryan Casey, Feng Gao, Michael Kirschenheiter, Siyi Li and Shailendra Pandit in Journal of Accounting, Auditing & Finance

Supplemental material, sj-docx-4-npx-10.1177_1934578X231152309 for Distinguish the Characteristic Mechanism of 3 Drug Pairs of Corydalis Rhizome in Ameliorating Angina Pectoris: Network Pharmacology and Meta-Analysis by Zhenwei Zhai, Zhishan Zhu, Fanjing Kong, Danni Xie, Jie Cai, Jingyi Dai, Yanmei Zhong, Yanxiong Gan, Shichao Zheng, Ying Xu and Tao Sun in Natural Product Communications

Supplemental material, sj-docx-5-npx-10.1177_1934578X231152309 for Distinguish the Characteristic Mechanism of 3 Drug Pairs of Corydalis Rhizome in Ameliorating Angina Pectoris: Network Pharmacology and Meta-Analysis by Zhenwei Zhai, Zhishan Zhu, Fanjing Kong, Danni Xie, Jie Cai, Jingyi Dai, Yanmei Zhong, Yanxiong Gan, Shichao Zheng, Ying Xu and Tao Sun in Natural Product Communications

Supplemental material, sj-docx-6-npx-10.1177_1934578X231152309 for Distinguish the Characteristic Mechanism of 3 Drug Pairs of Corydalis Rhizome in Ameliorating Angina Pectoris: Network Pharmacology and Meta-Analysis by Zhenwei Zhai, Zhishan Zhu, Fanjing Kong, Danni Xie, Jie Cai, Jingyi Dai, Yanmei Zhong, Yanxiong Gan, Shichao Zheng, Ying Xu and Tao Sun in Natural Product Communications

Supplemental material, sj-docx-1-npx-10.1177_1934578X231152309 for Distinguish the Characteristic Mechanism of 3 Drug Pairs of Corydalis Rhizome in Ameliorating Angina Pectoris: Network Pharmacology and Meta-Analysis by Zhenwei Zhai, Zhishan Zhu, Fanjing Kong, Danni Xie, Jie Cai, Jingyi Dai, Yanmei Zhong, Yanxiong Gan, Shichao Zheng, Ying Xu and Tao Sun in Natural Product Communications

Recombinant human TPO (rhTPO) is effective for refractory/relapsed primary immune thrombocytopenia (ITP), but optimal dosing regimen remains elusive. In this multicenter, randomized, controlled trial, a total of 282 adult ITP patients (mean age 47.3 years; 82 men) with a platelet count ≤30 × 109/L or >30 × 109/L with active bleeding randomly received a once daily (QD) subcutaneous injection of 7500 U (n = 64) or 15000 U rhTPO for 14 injections, or 15000 U...

To investigate the effects and mechanisms of 4-(1H-indol-1-yl)-4-oxobutanoic acid spliced podophyllotoxin derivatives (3a–3l) on tumor cells. The MTT method was adopted to evaluate (3a–3l) antitumor activity in vitro against A549 cells, A549/DDP cells, MCF-7 cells. The results showed that compound 3l had the most prominent inhibitory effect and high selectivity with IC50 18.53 ± 1.51 µM against A549/DDP cells. Meanwhile, the effects of compound 3l on the nuclear state, cell cycle and apoptosis of A549/DDP...

Supplementary Material for Irigenin attenuates lipopolysaccharide-induced acute lung injury by inactivating the mitogen-activated protein kinase (MAPK) signaling pathway by Dan Liu, Qing Wang, Wen Yuan and Qiang Wang in International Journal of Human & Experimental Toxicology

This document give the details on test of nonlinear optical absorption coefficients

Information about Z-scan test

Information about Z-scan test

Many primary tumours have low levels of molecular oxygen (hypoxia), and hypoxic tumours respond poorly to therapy. Pan-cancer molecular hallmarks of tumour hypoxia remain poorly understood, with limited comprehension of its associations with specific mutational processes, non-coding driver genes and evolutionary features. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumour types, we quantify hypoxia in 1188 tumours spanning...

Supplement 1

Supplemental material, sj-docx-1-cll-10.1177_09636897231154579 for Human Menstrual Blood–Derived Endometrial Stem Cells Promote Functional Recovery by Improving the Inflammatory Microenvironment in a Mouse Spinal Cord Injury Model by Yaping Shi, Yunfei Liu, Bichao Zhang, Xiaoying Li, Juntang Lin and Ciqing Yang in Cell Transplantation

Supplemental material, sj-docx-1-chl-10.1177_17475198221150384 for Fischer indole synthesis in DMSO/AcOH/H2O under continuous flow conditions by Mei Wang, Shenghu Yan, Yue Zhang and Shunlin Gu in Journal of Chemical Research

Supplemental Document