112 Works

Viral RNA level, serum antibody responses, and transmission risk in recovered COVID-19 patients with recurrent positive SARS-CoV-2 RNA test results: a population-based observational cohort study

Chao Yang, Min Jiang, Xiaohui Wang, Xiujuan Tang, Shisong Fang, Hao Li, Le Zuo, Yixiang Jiang, Yifan Zhong, Qiongcheng Chen, Chenli Zheng, Lei Wang, Shuang Wu, Weihua Wu, Hui Liu, Jing Yuan, Xuejiao Liao, Zhen Zhang, Xiaolu Shi, Yijie Geng, Huan Zhang, Huanying Zheng, Min Wan, Linying Lu, Xiaohu Ren … & Qinghua Hu
Managing recovered COVID-19 patients with recurrent-positive SARS-CoV-2 RNA test results is challenging. We performed a population-based observational study to characterize the viral RNA level and serum antibody responses in recurrent-positive patients and evaluate their viral transmission risk. Of 479 recovered COVID-19 patients, 93 (19%) recurrent-positive patients were identified, characterized by younger age, with a median discharge-to-recurrent-positive length of 8 days. After readmission, recurrent-positive patients exhibited mild (28%) or absent (72%) symptoms, with no disease progression....

Viral RNA level, serum antibody responses, and transmission risk in recovered COVID-19 patients with recurrent positive SARS-CoV-2 RNA test results: a population-based observational cohort study

Chao Yang, Min Jiang, Xiaohui Wang, Xiujuan Tang, Shisong Fang, Hao Li, Le Zuo, Yixiang Jiang, Yifan Zhong, Qiongcheng Chen, Chenli Zheng, Lei Wang, Shuang Wu, Weihua Wu, Hui Liu, Jing Yuan, Xuejiao Liao, Zhen Zhang, Xiaolu Shi, Yijie Geng, Huan Zhang, Huanying Zheng, Min Wan, Linying Lu, Xiaohu Ren … & Qinghua Hu
Managing recovered COVID-19 patients with recurrent-positive SARS-CoV-2 RNA test results is challenging. We performed a population-based observational study to characterize the viral RNA level and serum antibody responses in recurrent-positive patients and evaluate their viral transmission risk. Of 479 recovered COVID-19 patients, 93 (19%) recurrent-positive patients were identified, characterized by younger age, with a median discharge-to-recurrent-positive length of 8 days. After readmission, recurrent-positive patients exhibited mild (28%) or absent (72%) symptoms, with no disease progression....

Additional file 1 of In-hospital initiation of PCSK9 inhibitor and short-term lipid control in patients with acute myocardial infarction

Bowen Lou, Hui Liu, Yongbai Luo, Gulinigaer Tuerhong Jiang, Haoyu Wu, Chen Wang, Yue Wu, Bo Zhou, Zuyi Yuan, Jianqing She & Junhui Liu
Additional file 1: Fig. S1. Jitter and hist plots (statin plus evolocumab-based PSM).

Constructing new acid-activated anticancer peptide by attaching a desirable anionic binding partner peptide

Yun Zhang, Linlin Chang, Hexin Bao, Xiaoyan Wu, Hui Liu, Sanhu Gou, Jingying Zhang & Jingman Ni
Improving the cell selectivity of anticancer peptides (ACPs) is a major hurdle in their clinical utilisation. In this study, a new acid-activated ACP was designed by conjugating a cationic ACP LK to its anionic binding partner peptide (LEH) via a disulphide linker to trigger antitumor activity at acidic pH while masking its killing activity at normal pH. Three anionic binding peptides containing different numbers of glutamic acid (Glu) and histidine were engineered to obtain an...

Additional file 1 of Preoperatively predicting early response of HCC to TACE using clinical indicators and MRI features

Zhi-Wei Li, A-Hong Ren, Da-Wei Yang, Hui Xu, Jian Wei, Chun-Wang Yuan, Zhen-Chang Wang & Zheng-Han Yang
Additional file 1: Table S1. MR parameters.

Additional file 2 of Preoperatively predicting early response of HCC to TACE using clinical indicators and MRI features

Zhi-Wei Li, A-Hong Ren, Da-Wei Yang, Hui Xu, Jian Wei, Chun-Wang Yuan, Zhen-Chang Wang & Zheng-Han Yang
Additional file 2: Table S2. MRI features of the 91 patients and agreement between readers.

Additional file 1 of Treadmill exercise promotes E3 ubiquitin ligase to remove amyloid β and P-tau and improve cognitive ability in APP/PS1 transgenic mice

Longfei Xu, Mingzhe Li, Aili Wei, Miaomiao Yang, Chao Li, Ran Liu, Yuejun Zheng, Yuxin Chen, Zixi Wang, Kun Wang & Tianhui Wang
Additional file 1: Treadmill Exercise Reduces Body Weight in APP/PS1 Transgenic Mice.

Additional file 1 of Comparison of clinical outcomes of frozen-thawed D5 and D6 blastocysts undergoing preimplantation genetic testing

Guanling Yu, Shuiying Ma, Hui Liu, Yujin Liu, Haozhen Zhang, Wenjia Zhang & Keliang Wu
Additional file 1: Figure S1. More representative images of blastocysts from frozen-thawed D5 (A) and frozen-thawed D6 (B). Figure S2. Representative images of blastocysts from frozen-thawed D5 (A) and frozen-thawed D6 (B) during aspiration. Figure S3. Comparisons of the pregnancy ratio (A) and abortion ratio (B) between patients received high quality of blastocyst transplantation from frozen-thawed D5 and general quality from frozen-thawed D6. Fisher’s exact test. Figure S4. Comparisons of the pregnancy ratio (A) and...

Additional file 1 of Comparison of clinical outcomes of frozen-thawed D5 and D6 blastocysts undergoing preimplantation genetic testing

Guanling Yu, Shuiying Ma, Hui Liu, Yujin Liu, Haozhen Zhang, Wenjia Zhang & Keliang Wu
Additional file 1: Figure S1. More representative images of blastocysts from frozen-thawed D5 (A) and frozen-thawed D6 (B). Figure S2. Representative images of blastocysts from frozen-thawed D5 (A) and frozen-thawed D6 (B) during aspiration. Figure S3. Comparisons of the pregnancy ratio (A) and abortion ratio (B) between patients received high quality of blastocyst transplantation from frozen-thawed D5 and general quality from frozen-thawed D6. Fisher’s exact test. Figure S4. Comparisons of the pregnancy ratio (A) and...

Additional file 3 of Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Yangyang Li, Wenzhen Zhao, Rong Fu, Zhuoyao Ma, Yanqin Hu, Yue Liu & Zhide Ding
Additional file 3.

Additional file 6 of Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Yangyang Li, Wenzhen Zhao, Rong Fu, Zhuoyao Ma, Yanqin Hu, Yue Liu & Zhide Ding
Additional file 6.

Additional file 8 of Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Yangyang Li, Wenzhen Zhao, Rong Fu, Zhuoyao Ma, Yanqin Hu, Yue Liu & Zhide Ding
Additional file 8.

Additional file 9 of Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Yangyang Li, Wenzhen Zhao, Rong Fu, Zhuoyao Ma, Yanqin Hu, Yue Liu & Zhide Ding
Additional file 9.

Additional file 10 of Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Yangyang Li, Wenzhen Zhao, Rong Fu, Zhuoyao Ma, Yanqin Hu, Yue Liu & Zhide Ding
Additional file 10.

Additional file 12 of Endoplasmic reticulum stress increases exosome biogenesis and packaging relevant to sperm maturation in response to oxidative stress in obese mice

Yangyang Li, Wenzhen Zhao, Rong Fu, Zhuoyao Ma, Yanqin Hu, Yue Liu & Zhide Ding
Additional file 12.

Supplemental Material - Bortezomib induces cellular senescence in A549 lung cancer cells by stimulating telomere shortening

Lei Wang, Hang Yin, Shiren Huang, Sini Huang, Congcong Huang, Zhao Zhang & Hui Liu
Supplemental Material for Bortezomib induces cellular senescence in A549 lung cancer cells by stimulating telomere shortening by Lei Wang, Hang Yin, Shiren Huang, Sini Huang, Congcong Huang, Zhao Zhang, amd Hui Liu in Human & Experimental Toxicology

Additional file 4 of CT radiomics-based long-term survival prediction for locally advanced non-small cell lung cancer patients treated with concurrent chemoradiotherapy using features from tumor and tumor organismal environment

Nai-Bin Chen, Mai Xiong, Rui Zhou, Yin Zhou, Bo Qiu, Yi-Feng Luo, Su Zhou, Chu Chu, Qi-Wen Li, Bin Wang, Hai-Hang Jiang, Jin-Yu Guo, Kang-Qiang Peng, Chuan-Miao Xie & Hui Liu
Additional File 4. Tumor response after CCRT in the low-risk and high-risk group

Additional file 2 of Evolution and functional analysis of the GRAS family genes in six Rosaceae species

Yibo Bai, Hui Liu, Kaikai Zhu & Zong-Ming Cheng
Additional file 2: Fig. S2. Phylogenetic tree of GRAS genes in the six Rosaceae species and Arabidopsis.

Regional shape alteration of left thalamus associated with late chronotype in young adults

Cheng Xu, Hui Xu, Zhenliang Yang & Chenguang Guo
Chronotype reflects individual differences in circadian rhythms and influences individual psychology and behavior. Previous studies found altered subcortical structures are closely related to individual chronotypes. However, these studies have been conducted mainly using voxel-based morphometry and traditional volume measurement methods with certain limitations. This study aimed to investigate subcortical aberrant volume and shape patterns in late chronotypes (LC) young adults compared to early chronotypes (EC) young adults. Magnetic resonance imaging (MRI) scanning and chronotype assessment...

Sesquiterpenoids isolated from feces-residing Streptomyces sp. inhibit the cellular entry of influenza a viruses

Shengsheng Lu, Jianan Hu, Xi Xie, Ruifeng Huang & Jian He
Five metabolites (1–5), including two new sesquiterpenoids, designated ganodermanol L (1) and 4α,15-epoxyeudesmane-1β,6α,11-triol (2), together with three known structurally related compounds (3-5), have been isolated from the cultures of Streptomyces sp. XM17, a bacteria residing in the fresh feces of the giant panda Ailuropoda melanoleuca. The structures of 1–2 were established on the basis of extensive spectroscopic analyses, including 1D- and 2D-NMR (1H-1H COSY, HMQC, HMBC and NOESY) experiments. Furthermore, the absolute configuration of 1...

Additional file 3 of CT radiomics-based long-term survival prediction for locally advanced non-small cell lung cancer patients treated with concurrent chemoradiotherapy using features from tumor and tumor organismal environment

Nai-Bin Chen, Mai Xiong, Rui Zhou, Yin Zhou, Bo Qiu, Yi-Feng Luo, Su Zhou, Chu Chu, Qi-Wen Li, Bin Wang, Hai-Hang Jiang, Jin-Yu Guo, Kang-Qiang Peng, Chuan-Miao Xie & Hui Liu
Additional File 3 Patient characteristics

Additional file 2 of Bone marrow mesenchymal stem cells regulate the dysfunction of NK cells via the T cell immunoglobulin and ITIM domain in patients with myelodysplastic syndromes

Zhaoyun Liu, Yixuan Guo, Lei Huang, Yue Jia, Hui Liu, Fengping Peng, Lixiang Duan, Hongkai Zhang & Rong Fu
Additional file 1: Supplementary tables and figures.

Synthesis of spirocyclopropanes via iodine-promoted bimolecular cyclization of 2-benzylidene 1,3-indandiones

Zeng-Yang He, Yong Ning, Yu-Fei Zhao, Hong-Lin Diao, Peng Zou, Wen-Bin Wang, Jun-Sheng Shu & Hui Xu
A novel and efficient iodine-promoted bimolecular annulation of 2-benzylidene 1,3-indandiones has been developed. Following this protocol, a series of spirocyclopropane derivatives were furnished in good to excellent yields. The present protocol features mild conditions, short reaction time, high efficiency, good chemoselectivity and remarkable functional group tolerance.

Additional file 4 of In-hospital initiation of PCSK9 inhibitor and short-term lipid control in patients with acute myocardial infarction

Bowen Lou, Hui Liu, Yongbai Luo, Gulinigaer Tuerhong Jiang, Haoyu Wu, Chen Wang, Yue Wu, Bo Zhou, Zuyi Yuan, Jianqing She & Junhui Liu
Additional file 4: Table. S2. Summary of triple therapy-based PSM.

Additional file 1 of Preoperatively predicting early response of HCC to TACE using clinical indicators and MRI features

Zhi-Wei Li, A-Hong Ren, Da-Wei Yang, Hui Xu, Jian Wei, Chun-Wang Yuan, Zhen-Chang Wang & Zheng-Han Yang
Additional file 1: Table S1. MR parameters.

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