107 Works

The symptom representation of posttraumatic stress disorder in a sample of unaccompanied and accompanied refugee minors in Germany: a network analysis

Elisa Pfeiffer, Thorsten Sukale, Lauritz Rudolf Floribert Müller, Paul Lukas Plener, Rita Rosner, Joerg Michael Fegert, Cedric Sachser & Johanna Unterhitzenberger
Background: Given the unprecedented number of traumatized refugee minors in Europe and the increased prevalence of mental disorders such as PTSD in this vulnerable population, new methodologies that help us to better understand their symptomatology are crucial. Network analysis might help clinicians to both understand which symptoms might trigger other symptoms, and to identify relevant targets for treatment. However, to date only two studies have applied the network analysis approach to an (adult) refugee population...

Does the therapist matter? Therapist characteristics and their relation to outcome in trauma-focused cognitive behavioral therapy for children and adolescents

Elisa Pfeiffer, Silje Mørup Ormhaug, Dunja Tutus, Tonje Holt, Rita Rosner, Tore Wentzel Larsen & Tine K. Jensen
There is a broad evidence-base for the effectiveness of Trauma-Focused Cognitive-Behavioral Therapy (TF-CBT) in treating children and adolescents with posttraumatic stress disorder (PTSD). The effect of therapist characteristics on patient symptoms has been neglected in psychotraumatology research and necessitates further investigation. This study aims to investigate the impact of therapist characteristics (gender, clinical experience and theoretical background) on posttraumatic stress symptoms (PTSS) in a heterogeneous and international sample of traumatized children and adolescents. Data from...

Analyse von Mortalität nach Hüftfraktur auf Individual-, Krankenhaus- und regionaler Ebene in Deutschland

Claudia Schulz, Hans-Helmut König, Kilian Rapp, Clemens Becker, Dietrich Rothenbacher & Gisela Büchele
Einleitung. Die Mehrzahl der Studien, die die Mortalität nach Hüftfraktur analysieren, konzentrieren sich auf die Untersuchungsebene der Patienten und weniger auf die von Krankenhäusern oder Regionen. Ein tiefgreifendes Verständnis der beeinflussenden Faktoren aller Ebenen könnte jedoch dabei helfen, relevante Ungleichheiten aufzudecken, um Präventionsmaßnahmen zu motivieren und Verbesserungen in der Versorgung anzuregen. Daher untersuchte diese Studie die Variation der Mortalität nach Hüftfraktur auf Individual-, Krankenhaus- und regionaler Ebene in Deutschland. Methodik. Diese retrospektive Kohortenstudie basiert auf...

Mechanisms of change in Internet- and mobile-based interventions for PTSD: a systematic review and meta-analysis

Lena Steubl, Cedric Sachser, Harald Baumeister & Matthias Domhardt
Background: While Internet- and mobile-based interventions (IMIs) are potential options to increase the access to evidence-based therapies for post-traumatic stress disorder (PTSD), comprehensive knowledge on their working mechanisms is still scarce. Objective: We aimed to evaluate studies investigating the efficacy and mechanisms of change in IMIs for adults with PTSD. Method: In this systematic review and meta-analysis (PROSPERO CRD42019130314), five databases were consulted to identify relevant studies, complemented by forward (i.e. citation search) and backward...

Age-related similarities and differences in networks of acute trauma-related stress symptoms in younger and older preschool children

Lasse Bartels, Cedric Sachser & Markus A. Landolt
Background: Prior research on trauma-exposed preschool children has found various levels of trauma-related stress symptoms depending on age, which might be explained by developmental factors. Objective: This study uses network analysis to extend prior research and compare symptom presentation in younger and older preschoolers in the acute phase (first 4 weeks) following a potentially traumatic event. Method: Parent-reported trauma-related acute stress symptoms were assessed using the Pediatric Emotional Distress Scale – Early Screener via www.kidtrauma.com....

Age-related similarities and differences in networks of acute trauma-related stress symptoms in younger and older preschool children

Lasse Bartels, Cedric Sachser & Markus A. Landolt
Background: Prior research on trauma-exposed preschool children has found various levels of trauma-related stress symptoms depending on age, which might be explained by developmental factors. Objective: This study uses network analysis to extend prior research and compare symptom presentation in younger and older preschoolers in the acute phase (first 4 weeks) following a potentially traumatic event. Method: Parent-reported trauma-related acute stress symptoms were assessed using the Pediatric Emotional Distress Scale – Early Screener via www.kidtrauma.com....

The child and Adolescent Trauma Screen 2 (CATS-2) – validation of an instrument to measure DSM-5 and ICD-11 PTSD and complex PTSD in children and adolescents

Cedric Sachser, Lucy Berliner, Elizabeth Risch, Rita Rosner, Marianne S. Birkeland, Rebekka Eilers, Gertrud S. Hafstad, Elisa Pfeiffer, Paul L. Plener & Tine K. Jensen
The study examined the psychometric properties of the Child and Adolescent Trauma Screen 2 (CATS-2) as a measure of posttraumatic stress disorder (PTSD) according to DSM-5 and (Complex) PTSD following the ICD-11 criteria in children and adolescents (7–17 years). Psychometric properties were investigated in an international sample of traumatized children and adolescents (N = 283) and their caregivers (N = 255). We examined the internal consistency (α), convergent and discriminant validity, the factor structure of...

Additional file 2 of Artificial intelligence-informed mobile mental health apps for young people: a mixed-methods approach on users’ and stakeholders’ perspectives

Christian Götzl, Selina Hiller, Christian Rauschenberg, Anita Schick, Janik Fechtelpeter, Unai Fischer Abaigar, Georgia Koppe, Daniel Durstewitz, Ulrich Reininghaus & Silvia Krumm
Additional file 2: Interview topic guide–expert interviews.

Additional file 3 of Artificial intelligence-informed mobile mental health apps for young people: a mixed-methods approach on users’ and stakeholders’ perspectives

Christian Götzl, Selina Hiller, Christian Rauschenberg, Anita Schick, Janik Fechtelpeter, Unai Fischer Abaigar, Georgia Koppe, Daniel Durstewitz, Ulrich Reininghaus & Silvia Krumm
Additional file 3: Online survey.

Additional file 5 of Artificial intelligence-informed mobile mental health apps for young people: a mixed-methods approach on users’ and stakeholders’ perspectives

Christian Götzl, Selina Hiller, Christian Rauschenberg, Anita Schick, Janik Fechtelpeter, Unai Fischer Abaigar, Georgia Koppe, Daniel Durstewitz, Ulrich Reininghaus & Silvia Krumm
Additional file 5: COREQ-Checklist.

Additional file 1 of Garvicin Q: characterization of biosynthesis and mode of action

Christian K. Desiderato, Katharina M. Hasenauer, Sebastian J. Reich, Oliver Goldbeck, Lalaina Holivololona, Kirill V. Ovchinnikov, Alexander Reiter, Marco Oldiges, Dzung B. Diep, Bernhard J. Eikmanns & Christian U. Riedel
Additional file 1. Data file with supplementary Figures and Tables S1-14.

sj-pdf-6-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-6-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

sj-pdf-6-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-6-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

Additional file 1 of Subcutaneous fat necrosis in newborns: a systematic literature review of case reports and model of pathophysiology

Leonie Frank, Stephanie Brandt & Martin Wabitsch
Additional file 1: Table S1. Included publication in analysis of the research question. Table S2. Excluded references and reason for exclusion.

Integrative pathway enrichment analysis of multivariate omics data

Marta Paczkowska, Jonathan Barenboim, Nardnisa Sintupisut, Natalie S Fox, Helen Zhu, Diala Abd-Rabbo, Miles W Mee, Paul C Boutros, Federico Abascal, Samirkumar B Amin, Gary D Bader, Rameen Beroukhim, Johanna Bertl, Keith A Boroevich, Søren Brunak, Peter J Campbell, Joana Carlevaro-Fita, Dimple Chakravarty, Calvin Wing Yiu Chan, Ken Chen, Jung Kyoon Choi, Jordi Deu-Pons, Priyanka Dhingra, Klev Diamanti, Lars Feuerbach … & L van’t Veer
Multi-omics datasets represent distinct aspects of the central dogma of molecular biology. Such high-dimensional molecular profiles pose challenges to data interpretation and hypothesis generation. ActivePathways is an integrative method that discovers significantly enriched pathways across multiple datasets using statistical data fusion, rationalizes contributing evidence and highlights associated genes. As part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancers across 38 tumor types, we integrated...

Additional file 1 of Mobilisation of critically ill patients receiving norepinephrine: a retrospective cohort study

Maximilian Lindholz, Clara M. Schellenberg, Julius J. Grunow, Simone Kagerbauer, Annette Milnik, Daniel Zickler, Stefan Angermair, Anett Reißhauer, Martin Witzenrath, Mario Menk, Sebastian Boie, Felix Balzer & Stefan J. Schaller
Additional file 1. Table S1. Individual elements of the Elixhauser index. Table S2. All Admission diagnoses with n > 50.

Additional file 1 of Visinin-like protein 1 levels in blood and CSF as emerging markers for Alzheimer’s and other neurodegenerative diseases

Steffen Halbgebauer, Petra Steinacker, Daniel Riedel, Patrick Oeckl, Sarah Anderl-Straub, Jolina Lombardi, Christine A. F. von Arnim, Magdalena Nagl, Armin Giese, Albert C. Ludolph & Markus Otto
Additional file 1: Supplementary material. Description of assay parallelism and pre-analytical stability.

sj-docx-1-jic-10.1177_08850666221132246 - Supplemental material for Comparison of Different Ultrasound Methods to Assess Changes in Muscle Mass in Critically ill Patients

Kristina E. Fuest, Hugo Lanz, Jana Schulz, Bernhard Ulm, Victoria A. Bennett, Julius J. Grunow, Björn Weiss, Manfred Blobner & Stefan J. Schaller
Supplemental material, sj-docx-1-jic-10.1177_08850666221132246 for Comparison of Different Ultrasound Methods to Assess Changes in Muscle Mass in Critically ill Patients by Kristina E. Fuest, Hugo Lanz, Jana Schulz, Bernhard Ulm, Victoria A. Bennett, Julius J. Grunow, Björn Weiss, Manfred Blobner and Stefan J. Schaller in Journal of Intensive Care Medicine

sj-pdf-11-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-11-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

sj-pdf-14-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-14-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

sj-pdf-4-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-4-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

sj-pdf-4-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-4-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

sj-pdf-8-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-8-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

Age-related similarities and differences in networks of acute trauma-related stress symptoms in younger and older preschool children

Lasse Bartels, Cedric Sachser & Markus A. Landolt
Prior research on trauma-exposed preschool children has found various levels of trauma-related stress symptoms depending on age, which might be explained by developmental factors. This study uses network analysis to extend prior research and compare symptom presentation in younger and older preschoolers in the acute phase (first 4 weeks) following a potentially traumatic event. Parent-reported trauma-related acute stress symptoms were assessed using the Pediatric Emotional Distress Scale – Early Screener via www.kidtrauma.com. First, the overall...

sj-pdf-2-msj-10.1177_13524585221134213 – Supplemental material for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis

Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg & Florian Deisenhammer
Supplemental material, sj-pdf-2-msj-10.1177_13524585221134213 for Cerebrospinal fluid kappa free light chains for the diagnosis of multiple sclerosis: A systematic review and meta-analysis by Harald Hegen, Janette Walde, Klaus Berek, Georgina Arrambide, Sharmilee Gnanapavan, Batia Kaplan, Michael Khalil, Ruba Saadeh, Charlotte Teunissen, Hayrettin Tumani, Luisa M Villar, Maria Alice V Willrich, Henrik Zetterberg and Florian Deisenhammer in Multiple Sclerosis Journal

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