3D printing technology has significant advantages in the processing field of vascular tissue engineering. We have developed KCMA/SA hydrogels based on methacrylated carrageenan (KCMA) and sodium alginate (SA), which have low viscosity and shear thinning properties and can be used for 3D printing. The physicochemical double cross-linked network structure leads to good mechanical properties. The composite hydrogels maintain the liquid crystallinity of KC, which causes the HUVECs to align. The KCMA/SA gel filaments printed by...

Supplemental material, sj-docx-1-car-10.1177_19476035231154511 for Integrated Analysis of Transcriptome Changes in Osteoarthritis: Gene Expression, Pathways and Alternative Splicing by Congming Li, Pengli Wei, Lei Wang, Qiang Wang, Hong Wang and Yangjun Zhang in CARTILAGE

Supplemental material, sj-docx-1-taj-10.1177_20406223231153097 for The efficacy of telemedicine for pain management in patients with cancer: a systematic review and meta-analysis by Wenyu Chen, Jie Huang, Zhifang Cui, Lei Wang, Liang Dong, Weifeng Ying and Ye Zhang in Therapeutic Advances in Chronic Disease

Additional file 1.

Additional file 1.

Additional file 1. Patient information bulletin and decision guide regarding colorectal cancer and ovaries.

Additional file 1. DNA analysis report.

Supplemental Material, sj-docx-1-ptd-10.1177_08968608221144395 for Outcomes of COVID-19 in peritoneal dialysis patients: A report by the European Renal Association COVID-19 Database by Alferso C Abrahams, Marlies Noordzij, Eric Goffin, J Emilio Sanchez, Casper FM Franssen, Priya Vart, Kitty J Jager, Madelon van Agteren, Adrian Covic, Sandip Mitra, Carlo Basile, Constantijn Konings, Marc H Hemmelder, Raphaël Duivenvoorden, Luuk B Hilbrands, Ron T Gansevoort and ERACODA Collaborators in Peritoneal Dialysis International

Supplemental material, sj-pdf-1-cpx-10.1177_21677026221137006 for Detecting Impending Symptom Transitions Using Early-Warning Signals in Individuals Receiving Treatment for Depression by Marieke A. Helmich, Arnout C. Smit, Laura F. Bringmann, Marieke J. Schreuder, Albertine J. Oldehinkel, Marieke Wichers and Evelien Snippe in Clinical Psychological Science

Increased understanding of chronic inflammatory diseases and the role of endothelial cell (EC) activation herein, have urged interest in sophisticated strategies to therapeutically intervene in activated EC to treat these diseases. Liposome-mediated delivery of therapeutic siRNA in inflammation-activated EC is such a strategy. In this study, we describe the design and characterisation of two liposomal siRNA delivery systems formulated with the cationic MC3 lipid or MC3/SAINT mixed lipids, referred to as MC3-O-Somes (MOS) and MC3/SAINT-O-Somes...

To guide better prevention and treatment and to develop research priorities, this study aims to create an overview of facilitators and barriers for the development and persistence of musculoskeletal complaints (MSCs) in individuals with upper limb absence (ULA). Exploratory mixed methods design. A focus group (FG) was organized with individuals with ULA about MSCs and associated factors. An inductive approach was employed to the transcript and the studies. A scoping review was performed to systematically...

Supplementary Material 1

Supplementary Material 2

Supplemental material, sj-pdf-1-jcb-10.1177_0271678X221135270 for Precision estimates of relative and absolute cerebral blood flow in Alzheimer’s disease and cognitively normal individuals by Fiona Heeman, Denise Visser, Maqsood Yaqub, Sander Verfaillie, Tessa Timmers, Yolande AL Pijnenburg, Wiesje M van der Flier, Bart NM van Berckel, Ronald Boellaard, Adriaan A Lammertsma, Sandeep SV Golla in Journal of Cerebral Blood Flow & Metabolism

Additional file 1. Table S1: Included university hospitals, Scientific Collaboration Impact, publications, and H-Index.

Revised Supporting information

To systematically review literature on nutritional intake, nutritional status and nutritional interventions, and to study their association with short- and long-term clinical outcomes in people with a major dysvascular lower limb amputation. PubMed, Ovid, CINAHL, and The Cochrane Library were searched. Studies were included if nutritional intake, nutritional status, or nutritional interventions in people with a major dysvascular lower limb amputation were analyzed. Of the 3038 unique papers identified, 30 studies were included. Methodological quality...

Our previous works have shown that tanshinone IIA inhibited maladaptive extracellular matrix remodeling in cardiac fibroblasts implicating its potential role in treating of pathologic cardiac remodeling. However, the intrinsically poor solubility and bioavailability of tanshinone IIA hindered its clinical application. Here we develop monomethoxy-poly (ethylene glycol)-poly (lactic acid)-D-α-Tocopheryl polyethylene glycol 1000 succinate (mPEG-PLA-TPGS) nanoparticle incorporating tanshinone IIA (tanshinone IIA-NPs) and study its efficacy in post-infarction left ventricular (LV) remodeling. Male C57BL/6 mice underwent left coronary...

Quantile treatment effects can be important causal estimands in the evaluation of biomedical treatments or interventions for health outcomes such as birthweight and medical cost. However, the existing estimators require either a propensity score model or a conditional density vector model is correctly specified, which is difficult to verify in practice. In this paper, we allow multiple models for propensity score and conditional density vector, then construct a class of calibration estimators based on multiple...

To analyze the feasibility of and pain-related tolerance to a maximal cardiopulmonary exercise test (CPET), and the relationship between the aerobic capacity and central sensitization (CS) in patients with chronic low back pain (CLBP). An observational study, combining a cross-sectional and a prospective 24-hour follow-up was performed. Participants underwent a maximal CPET on a cycle ergometer and were assessed with three measures of CS (CS Inventory, quantitative sensory testing and heart rate variability). Before the...

Additional file 1: Supplemental Material 1. Online questionnaire on PPC structures in Europe used for the study purpose.

Additional file 2: Supplemental Material 2. Topic blocks and definitions within the utilized pediatric palliative care questionnaire.

Additional file 3: Supplemental Material 3. Specialized pediatric palliative home care team composition.

Additional file 1: Supplementary Figure S1. Sample selection diagram. Supplementary Table S1. LTCF demographics represented as means (standard deviation) or counts (percentage- represented by %).

Additional file 2: Table S2. Immunohistochemical reaction protocols.