Additional file 3: Table S3. Antigen retrieval protocol.

Additional file 3: Table S3. Antigen retrieval protocol.

Additional file 2. National Health Commission of China for Guiding Principle of Clinical Use of Antibiotics.

Supplement 1

Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) is highly expressed in smokers, but little is known about the molecular mechanism of UCHL1 in airway epithelium and its possible role in affecting extracellular matrix (ECM) remodelling in the underlying submucosa. Since cigarette smoking is a major cause of lung diseases, we studied its effect on UCHL1 expression and DNA methylation patterns in human bronchial epithelial cells, obtained after laser capture micro-dissection (LCM) or isolated from residual tracheal/main stem...

Background: Risk factors for acute kidney injury (AKI) after Stanford type A aortic dissection (TAAD) repair are inconsistent in different studies. This meta-analysis systematically analyzed the risk factors so as to early identify the therapeutic targets for preventing AKI. Methods: Studies exploring risk factors for AKI after TAAD repair were searched from four databases from inception to June 2022. The synthesized incidence and risk factors of AKI and its impact on mortality were calculated. Results:...

The objective of this study is to investigate the incidence of low lean tissue index (LTI) and the risk factors for low LTI in peritoneal dialysis (PD) patients, including to establish risk prediction models. A total of 104 PD patients were enrolled from October 2019 to 2021. LTI was measured by bioimpedance spectroscopy. Multivariate logistic regression and machine learning were used to analyze the risk factors for low LTI in PD patients. Kaplan–Meier analysis was...

Abdominal aortic aneurysm (AAA) is life-threatening, its natural course is progressively sac expansion and rupture. Elegant studies have been conducted to investigate the molecular markers associated with AAA growth and expansion, this topic however, still needs to be further elucidated. This study aimed to identify potential genes for AAA growth and expansion based on comprehensive bioinformatics approaches. Firstly, 29 up-regulated genes were identified through DEGs analysis between large AAA and small AAA in GSE57691. Secondly,...

In this paper, we propose robust statistical inference and variable selection method for generalized linear models that accommodate the outliers, nonignorable dropouts and within-subject correlations. The purpose of our study is threefold. First, we construct the robust and bias-corrected generalized estimating equations (GEEs) by combining the Mallows-type weights, Huber's score function and inverse probability weighting approaches to against the influence of outliers and account for nonignorable dropouts. Subsequently, the generalized method of moments is utilized...

(1) To estimate the proportion of Dutch wheelchair users with spinal cord injury (SCI) who meet different SCI exercise guidelines; (2) to evaluate which demographic and lesion characteristics are associated with meeting these guidelines; (3) whether meeting these guidelines is associated with physical fitness and health. Based on the PASIPD questionnaire items, participants were allocated to meeting two SCI aerobic exercise guidelines, which differ in exercise load. Differences in personal, lesion, fitness, and health characteristics...

Venetoclax monotherapy is an effective option for patients with acute myeloid leukemia (AML). Venetoclax has also been used in non-myeloablative conditioning allogeneic hematopoietic stem cell transplantation (allo-HSCT) for high-risk AML with a tolerable toxicity profile. However, the efficacy and safety of a venetoclax-containing myeloablative conditioning (MAC) allo-HSCT regimen for high-risk AML have not been evaluated. To evaluate the safety and efficacy of a MAC regimen containing venetoclax for high-risk AML. From 25 February 2021 to...

Revised Supporting information

Reinforcements in metal composites are usually dispersed at grain boundaries. We here show that the rapid solidification during laser additive manufacturing enables the spontaneous engulfment of reinforcing particles inside aluminum grains, which helps to decouple the stress concentration induced by grain boundaries and reinforcements. The additively manufactured TiB2-Al composite possesses 30% increase in tensile strength and nearly tripled ductility as compared with composite obtained by the traditional method. Our experimental investigations indicate that the intragranular...

Gas chromatography – tandem mass spectrometry (GC-MS/MS) using formic acid as a protective agent is reported for the determination of acrylic resin monomers in food contact packaging paper. The analytes were extracted by ethanol mixed with formic acid with 2-phenylethyl propionate as the internal standard. The extract was separated by a 6% cyanopropylbenzene-94% dimethylsiloxane ultra-inert chromatographic column and analyzed by GC-MS/MS in multiple reaction monitoring (MRM) mode. 13 acrylic resin monomers including acrylic acid, styrene,...

Endothelial function may improve with enhanced external counterpulsation (EECP) or acupuncture. This study aimed to evaluate the feasibility of acupoint stimulation combined with EECP (acupoint-EECP) for endothelial cell function in patients with essential hypertension. Thirty essential hypertensive patients were, randomly divided into two groups, with 15 patients in the acupoint-EECP group, and 15 patients in the control group, of which 3 cases were lost by week 6. Both groups were treated with continued medicine. The...

Endothelial function may improve with enhanced external counterpulsation (EECP) or acupuncture. This study aimed to evaluate the feasibility of acupoint stimulation combined with EECP (acupoint-EECP) for endothelial cell function in patients with essential hypertension. Thirty essential hypertensive patients were, randomly divided into two groups, with 15 patients in the acupoint-EECP group, and 15 patients in the control group, of which 3 cases were lost by week 6. Both groups were treated with continued medicine. The...

Supplemental figures and tables for the research article "A proteomics approach to identify COPD-related changes in lung fibroblasts" by N.J. Bekker et al.

Supplemental figures and tables for the research article "A proteomics approach to identify COPD-related changes in lung fibroblasts" by N.J. Bekker et al.

Supplemental material, sj-docx-2-pie-10.1177_09544089231160003 for Analyzing the tribological and mechanical performance of Al-6061 with rare earth oxides: An experimental analysis by Vipin Kumar Sharma, Pardeep Kumar, Shalom Akai, Vinod Kumar and Ravinder Singh Joshi in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering

Supplemental material, sj-docx-2-pie-10.1177_09544089231160003 for Analyzing the tribological and mechanical performance of Al-6061 with rare earth oxides: An experimental analysis by Vipin Kumar Sharma, Pardeep Kumar, Shalom Akai, Vinod Kumar and Ravinder Singh Joshi in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering

Additional file 1.

Revised Supporting information

Revised Supporting information

A detailed techno-economic analysis and life cycle assessment (LCA) of a novel bio-refinery that produces xylitol from sugarcane bagasse are provided. The proposed process includes dilute acid pretreatment in pressurized conditions followed by fermentation (upstream section). The fermentation broth is then sent for separation and purification to the downstream section. Calculations are performed for a plant with 4 t/h of dry bagasse throughput. With a fermentation yield of 0.54 g xylitol per g of xylose,...

Supplemental Material, sj-docx-1-ptd-10.1177_08968608221144395 for Outcomes of COVID-19 in peritoneal dialysis patients: A report by the European Renal Association COVID-19 Database by Alferso C Abrahams, Marlies Noordzij, Eric Goffin, J Emilio Sanchez, Casper FM Franssen, Priya Vart, Kitty J Jager, Madelon van Agteren, Adrian Covic, Sandip Mitra, Carlo Basile, Constantijn Konings, Marc H Hemmelder, Raphaël Duivenvoorden, Luuk B Hilbrands, Ron T Gansevoort and ERACODA Collaborators in Peritoneal Dialysis International