In this work, an efficient synthesis of 3-hydroxy chromones was accomplished through oxidative cyclization mediated by lipase. This enzymatic process has salient features of environmental friendliness, mild reaction condition, satisfactory yield, green reusable biocatalyst, and short reaction time. The proposed method expands the application of lipase in organic synthesis.

Supplementary Material 1

Supplementary Material 2

Additional file 1. Table S1. Distribution of diagnoses over the different centers.

Additional file 1. Contains supplementary Figs S1-S8.

Additional file 5. Review history.

3D printing technology has significant advantages in the processing field of vascular tissue engineering. We have developed KCMA/SA hydrogels based on methacrylated carrageenan (KCMA) and sodium alginate (SA), which have low viscosity and shear thinning properties and can be used for 3D printing. The physicochemical double cross-linked network structure leads to good mechanical properties. The composite hydrogels maintain the liquid crystallinity of KC, which causes the HUVECs to align. The KCMA/SA gel filaments printed by...

Pilots’ operation behavior in flight is associated with their mental state variables such as workload, situation awareness, stress, etc. The objective of this study was to investigate the dynamic process of mental workload for pilots who perform a risky flight task in simulated scenarios. Two empirical experiments were conducted to address this issue. In experiment one, 19 trainee pilots divided into high-risk and low-risk groups performed a target-search task in a low-altitude visual flight. The...

Additional file 1: Table S1. Studies on surgical interventions in pediatric uveitic glaucoma – primary outcomes.

Additional file 1: Supplementary Figure S1. Sample selection diagram. Supplementary Table S1. LTCF demographics represented as means (standard deviation) or counts (percentage- represented by %).

Additional file 1. Supplementary figure 1. Correlation plot of the 75 proteins included in the study in healthy controls and patients with severe infections. The correlation matrix was generated using the “psych” package in R and it was plotted using corrplot from the “rstatix” package. The colours represent the degree of pairwise correlation based on Spearman’s rank correlation coefficient. Positive correlations are depicted in red, while negative correlations are in blue. The size of the...

Additional file 1. Supplementary figure 1. Correlation plot of the 75 proteins included in the study in healthy controls and patients with severe infections. The correlation matrix was generated using the “psych” package in R and it was plotted using corrplot from the “rstatix” package. The colours represent the degree of pairwise correlation based on Spearman’s rank correlation coefficient. Positive correlations are depicted in red, while negative correlations are in blue. The size of the...

Additional file 2. Supplementary tables. Supplementary Table 1 shows the results from the differential abundance analysis between patients with severe infections and healthy controls. Supplementary Table 2 shows the results from the differential abundance analysis between the two endotypes.

Additional file 1. Patient information bulletin and decision guide regarding colorectal cancer and ovaries.

Additional file 1. Supplementary methods also including the following tables and figures Table S2. List of BCAC studies (including ABCS source) with the corresponding country and geographic area. Table S4: Clinical utility of the 5-year contralateral breast cancer risk prediction models (PredictCBC-1A with PredictCBC-2.0A and PredictCBC-1B with PredictCBC-2.0B). Figure S1. Visual assessment of calibration through calibration plots in the internal–external cross-validation at 5 years for the PredictCBC-2.0A model. Figure S2. Visual assessment of calibration through...

Additional file 1. Table S1: Included university hospitals, Scientific Collaboration Impact, publications, and H-Index.

Supplemental material, sj-docx-1-smo-10.1177_20503121221133935 for Food taboos among pregnant women and associated factors in eastern Ethiopia: A community-based cross-sectional study by Wbalem Amare, Abera Kenay Tura, Agumasie Semahegn and Kedir Teji Roba in SAGE Open Medicine

Additional file 1: Supplemental Material 1. Online questionnaire on PPC structures in Europe used for the study purpose.

Additional file 2. National Health Commission of China for Guiding Principle of Clinical Use of Antibiotics.

Additional file 1. Catalogue for Clinical Application of Antibacterial Drugs.

In this work, an efficient synthesis of 3-hydroxy chromones was accomplished through oxidative cyclization mediated by lipase. This enzymatic process has salient features of environmental friendliness, mild reaction condition, satisfactory yield, green reusable biocatalyst, and short reaction time. The proposed method expands the application of lipase in organic synthesis.

Additional file 1: Fig. S1. Plot of population-averaged input function. The y-axis is in logarithmic scale. Fig. S2. Bland–Altman plot of lesion Ki differences obtained with the IDIF minus the PIF scaled to the scan time interval at 30–60 min p.i. (PIF_30) (A), and the PIF scaled to the IDIF at shorter scan time intervals p.i. (PIF_40 and PIF_50) (B and C). For readability, the scales have been adjusted per subfigure.

Additional file 1: Fig. S1. Plot of population-averaged input function. The y-axis is in logarithmic scale. Fig. S2. Bland–Altman plot of lesion Ki differences obtained with the IDIF minus the PIF scaled to the scan time interval at 30–60 min p.i. (PIF_30) (A), and the PIF scaled to the IDIF at shorter scan time intervals p.i. (PIF_40 and PIF_50) (B and C). For readability, the scales have been adjusted per subfigure.

Additional file 1.

Additional file 1.