Scabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unravelled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. The prevalence and incidence of scabies tend to a moderate increase after age 70....

Scabies remains a significant public health concern globally, affecting people of all ages, races, and socioeconomic groups. The epidemic characteristics of scabies are yet unraveled, especially in high-income countries and elderly population. In this study, we sought to investigate incidence and prevalence and their trends of scabies worldwide from 1990 to 2017 via the Global Burden of Disease (GBD) Study 2017. The prevalence and incidence of age-standardized rate (ASR) of scabies tend to a moderate...

Worldwide emergence of Salmonella enterica serovar Newport (S. Newport) infection in humans, in parallel with a significant increasing prevalence of antimicrobial resistance (AR), is a serious public health concern. However, the prevalence of S. Newport resistance in China remains largely unknown. A retrospective study of 287 S. Newport clinical isolates collected during 1997–2018 was undertaken for characterization of AR profiles using the micro-dilution assay. We found a recent emergence of colistin resistance in four Chinese...

Co-occurrence of hypervirulence and KPC-2 carbapenem resistant phenotypes in a highly-transmissible ST11 clone ofKlebsiella pneumoniae has elicited deep concerns from public health stand point. To address this puzzle, we conducted a large-scale epidemiological, clinical and genomic study of K. pneumonia ST11 clones with both hypervirulence and carbapenem resistance in two tertiary hospitals in Zhejiang province. Most of the patients (15/23) were diagnosed with exclusively carbapenem-resistant K. pneumoniae (CRKP) infections. Ten death cases were reported, some...

Rice straw is one of the major agricultural residues that is generated enormously in Asian countries. Thus, it is critical to develop an efficient process of converting this residue into valuable compounds in replacing fossil-based products. Herein, we developed an economically viable cement catalyst to pyrolyze the rice straw into bio-oil and fuel gas in a batch-type reactor. Under the optimized conditions, the maximum bio-oil yield of 41.07 wt.%, and gas yield of 30.53 wt.%...

Few mental health assessment tools are available for people with hearing loss (HL) in China. The Acceptance and Action Questionnaire-Adult Hearing Loss (AAQ-AHL) has been specifically designed to assess psychological inflexibility in adults with HL and may help assess mental health status promptly for targeted psychological interventions. The study aimed to investigate the cross-cultural validity and reliability of the Chinese version of the AAQ-AHL to assess its applicability to teenagers and adults with HL in...

To get additional insight into the genetic factors of attention deficit hyperactivity disorder (ADHD). First, we performed a transcriptome-wide association study (TWAS) integrating human cerebellum-specific variant-expression/splicing correlations to identify ADHD susceptibility genes. Then, the associations between expression/splicing quantitative trait loci (eQTLs/sQTLs) of the transcriptome-wide significant genes and ADHD were observed in a case-control study of Han Chinese children. Furthermore, dual luciferase reporter gene assays were performed to validate the regulatory function of ADHD risk variants....

It was previously reported that the ratio of soluble fms-like tyrosine kinase-1 (sFlt-1) to placental growth factor (PlGF) can predict the clinical onset of preeclampsia. This study seeks to validate the association between ratios of sFlt-1/PlGF with preeclampsia and to identify the contribution of ethnicity across diverse populations of the Xinjiang Uygur Autonomous Region. Pregnant women were classified into those with preeclampsia (n = 136) and healthy controls (n = 350). Serum levels of sFlt-1...

It was previously reported that the ratio of soluble fms-like tyrosine kinase-1 (sFlt-1) to placental growth factor (PlGF) can predict the clinical onset of preeclampsia. This study seeks to validate the association between ratios of sFlt-1/PlGF with preeclampsia and to identify the contribution of ethnicity across diverse populations of the Xinjiang Uygur Autonomous Region. Pregnant women were classified into those with preeclampsia (n = 136) and healthy controls (n = 350). Serum levels of sFlt-1...

Immune checkpoint inhibitors (ICIs) -induced adverse events (AEs) have been reported affecting almost all human organs. However, studies about ocular AEs are few. A meta-analysis was performed to evaluate the risks of ICI-related ophthalmic AEs compare to chemotherapy. Methods: Eligible studies were selected from phase II/III randomized controlled trials investigating ICIs. The data were analyzed by R software and Stata. Odds ratio of treatment-related AE (trAEs) and nonspecific ophthalmic trAEs (NS-trAEs) were lower for PD-1/PD-L1...

There are no studies on the optimal intrusion force in orthodontic patients with the existing root resorption (RR). The study aimed to analyze the optimal intrusion force for central incisors with existing horizontal root resorption using the finite element method (FEM). We calculated the optimal intrusion force using the finite element method and curve fitting. We found that with the increase of the maxillary central incisor’s root horizontal resorption length, the optimal intrusion force interval’s...

Pot and field trials were conducted to investigate Cd uptake and phytoremediation efficiency of two Brassica napus cultivars (QY-1 and SYH) with applied water-soluble chitosan (WSC, Pot: 0, 2% and 4%; Field: 0 and 10 g·m−2) grown in Cd-contaminated soils. The results from the pot and field trials generally showed that WSC treatments significantly increased Cd concentrations in shoot and root tissues by 33.77–159.71% (except for SYH/JY) and 7.42–168.71% of two B. napus cultivars compared...

Lotus rhizome starch (LRS) is an important traditional processed product of lotus rhizome in China due to its good taste and high nutritional value. However, adulterated lotus rhizome starches are prevalent on the market. In this study, a novel method for the rapid detection of adulteration in LRS based on color reaction between ferrous sulfate (FS) and (-)-gallocatechin (GC) in LRS was studied. The polyphenols in LRS were analyzed by liquid chromatography-mass spectrometry (LC-MS/MS) as...

Some individuals with acute pancreatitis (AP) suffer from pancreatic necrosis. Diabetes affects the severity of AP, but whether diabetes influences pancreatic necrosis is unclear. This study aims to investigate the clinical characteristics of AP patients with and without diabetes as well as analyze the risk factors of pancreatic necrosis. A total of 625 AP patients participated in the study. Clinical and laboratory data were retrieved. Multivariate logistic regression analysis was used to identify the risk...

Additional file 2.

Additional file 8.

Supplemental material, sj-pdf-1-imr-10.1177_03000605221123882 for Refractory postherpetic neuralgia in a multiple myeloma patient with lenalidomide maintenance therapy: a case report by Xueqin Cao, Gang Wu, Bo Jiao and Xianwei Zhang in Journal of International Medical Research

Supplemental material, sj-pdf-1-imr-10.1177_03000605221123882 for Refractory postherpetic neuralgia in a multiple myeloma patient with lenalidomide maintenance therapy: a case report by Xueqin Cao, Gang Wu, Bo Jiao and Xianwei Zhang in Journal of International Medical Research

Additional file 1: Table S1. Search strategy of journal publications on HTA of selected medical devices. Table S2. Search strategy of journal publications on discussing HTA of medical devices. Figure S1. PRISMA flowchart of literature review of journal publications on discussing HTA of medical devices.

Capsicum chinense is one of the best ingredients for making chili sauces and extracting capsaicin. In this study, we identified 59 genes associated with shikimic acid, phenylpropane, unsaturated fatty acids, phenylalanine, valine, leucine, isoleucine and other metabolic pathways based on pepper genome. In the present study, 58 of the 59 genes involved in capsaicin synthesis were found to be unevenly distributed on 11 chromosomes, and several genes with the same number of exons and high...

Lamivudine is a first-line medication used for human immunodeficiency virus (HIV) treatment. To date, the population pharmacokinetics of lamivudine in Chinese HIV-infected adults have not been assessed. This study aimed to develop a population pharmacokinetic model for oral lamivudine in Chinese HIV-infected adults and to determine the optimal lamivudine dosage regimens. A total of 1113 samples, from 828 Chinese HIV-infected patients treated with lamivudine 300 mg every 24 hours, were pooled from two open-label, prospective...

There is a large uncertainty regarding the direction and magnitude of projected changes in the pattern and quantity of precipitation in future climate change scenarios. As changes in precipitation are likely to greatly impact plant diversity and biomass in desert ecosystems, we undertook a water addition/exclusion experiment to quantify the responses of plant diversity and biomass. To quantify the short-term impacts of changing the quantity of precipitation on plant species diversity and productivity in a...

There is a large uncertainty regarding the direction and magnitude of projected changes in the pattern and quantity of precipitation in future climate change scenarios. As changes in precipitation are likely to greatly impact plant diversity and biomass in desert ecosystems, we undertook a water addition/exclusion experiment to quantify the responses of plant diversity and biomass. To quantify the short-term impacts of changing the quantity of precipitation on plant species diversity and productivity in a...

Many panel data have the latent subgroup effect on individuals, and it is important to correctly identify these groups since the efficiency of resulting estimators can be improved significantly by pooling the information of individuals within each group. However, the currently assumed parametric and semiparametric relationship between the response and predictors may be misspecified, which leads to a wrong grouping result, and the nonparametric approach hence can be considered to avoid such mistakes. Moreover, the...

Many panel data have the latent subgroup effect on individuals, and it is important to correctly identify these groups since the efficiency of resulting estimators can be improved significantly by pooling the information of individuals within each group. However, the currently assumed parametric and semiparametric relationship between the response and predictors may be misspecified, which leads to a wrong grouping result, and the nonparametric approach hence can be considered to avoid such mistakes. Moreover, the...