Additional file 1. Patient individual interview guide.

Additional file 1: Supplemental Table 1. The preferred reporting items for systematic review and meta-analysis (PRISMA) 2020 statement. Supplemental Table 2. The search strategies of this meta-analysis until August 06, 2022. Supplemental Table 3. The excluded studies during the full-text screenings. Supplemental Table 4. The detailed characteristics of the included studies. Supplemental Table 6. Effect estimates and adjusted confounders of the included studies. Supplementary Table 7. Risk of bias assessment of the EAST-AFNET 4 trial....

Additional file 1: Table S1. Definition of cardiovascular health (CVH) metrics. Table S2. Detailed information on missing covariates. Table S3. Hazard ratios (HRs) and 95% confidence interval (CI) of diabetic complications by weight cardiovascular health (CVH) among people with type 2 diabetes. Table S4. Hazard ratios (HRs) and 95% confidence interval (CI) of all-cause mortality by weight cardiovascular health (CVH) among people with type 2 diabetes. Table S5. Hazard ratios (HRs) and 95% confidence interval...

Additional file 1. Supplemental analyses.

Additional file 1: Figure S1. The flow chart of Clip-Seq.

Prosapogenin A (also known as Progenin III and polyphyllin V), a secondary steroidal saponin in Dioscorea zingiberensis tubers, has more superior pharmacological activities than its primary form Protogracillin. Conventional preparation methods, such as column chromatography, and acidic hydrolysis, are of very low efficiency and limited scale due to tedious procedures and large consumption of organic solvent. This study aims to establish a convenient method for efficiently obtaining Prosapogenin A by enzymatic hydrolysis of abundant Protogracillin...

Additional file 1: Supplementary Material A. Sections of the interview guide, questions and probes.

Additional file 1: Supplementary Material A. Sections of the interview guide, questions and probes.

Danyikangtai powder has a definite therapeutic effect on pancreatitis. However, the internal mechanism is unclear. The purpose of this experiment is to quickly identify the blood components of danyikangtai powder and evaluate its efficacy. 25 blood components were identified by comparing the components with the same mass spectrometry information from in vivo and in vitro samples. The AR42J cells of the pancreatitis model were treated with drug-containing plasma, and the drug efficacy was evaluated by...

Danyikangtai powder has a definite therapeutic effect on pancreatitis. However, the internal mechanism is unclear. The purpose of this experiment is to quickly identify the blood components of danyikangtai powder and evaluate its efficacy. 25 blood components were identified by comparing the components with the same mass spectrometry information from in vivo and in vitro samples. The AR42J cells of the pancreatitis model were treated with drug-containing plasma, and the drug efficacy was evaluated by...

Additional file 2. Top 10 co-cited references related to coronary microvascular dysfunction.

Additional file 2. Top 10 co-cited references related to coronary microvascular dysfunction.

Purpose: Oncology studies employing digital dissection methodologies have provided some insight on the biological features of tumor microenvironment of Triple-negative breast cancer (TNBC), but molecular diagnostics rarely have therapeutic impact. We aimed to identify a novel prognostic biomarker to investigate immune characteristics of TNBC using transcriptomic features. Patients and Methods: We extracted whole transcriptome from breast cancer tissue of 30 TNBC patients and then used bioinformatics approaches to characterize the different immune cell contents in...

Additional file 1. Protocol for scoping review.

Additional file 2. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist.

Additional file 2. Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) Checklist.

Additional file 1. Original findings of the included studies (N = 39).

Additional file 1: Table 2. Knowledge questions (modified from Soldatou et al., 2020 [18]).

Additional file 1: Table S1. Names of the bile acids measured in tumor tissues. Table S2. Demographics of colon cancer patients from samples used within this study. Table S4. Comparison of bile acid abundance between RCCs and LCCs by sex and age. Table S5. Pearson correlation of glucuronic acid to bile acid abundances in patients with LCC ≥ 55 years old (n=99). Table S6. Correlations between prognosis-linked bile acid and T regulatory cell abundances in...

Additional file 3. R code for performing survival analysis.

Supplemental material, sj-docx-1-jop-10.1177_02698811221140008 for Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults by David Matuskey, Jean-Dominique Gallezot, Nabeel Nabulsi, Shannan Henry, Kristen Torres, Mark Dias, Gustavo A Angarita, Yiyun Huang, Susan E Shoaf, Richard E Carson and Shailly Mehrotra in Journal of Psychopharmacology

Triple-crossover randomized controlled intervention trial to test whether reduced exposure to household NO2 or fine particles results in reduced symptoms among children with persistent asthma. Children (n = 126) aged 5–11 years with persistent asthma living in homes with gas stoves and levels of NO2 15 ppb or greater recruited in Connecticut and Massachusetts (2015–2019) participated in an intervention involving three air cleaners configured for: (1) NO2 reduction: sham particle filtration and real NO2 scrubbing;...

Supplemental Material for Conductive, self-healing, and antibacterial Ag/MXene-PVA hydrogel as wearable skin-like sensors by Lumin Li, Xiaofeng Ji and Kai Chen in Journal of Biomaterials Applications

Detecting forest disturbances and attributing their contributing agents with Landsat time series (LTS) images has advanced substantially in recent years; however, whether different forest types require individual disturbance indices or specific disturbance thresholds to accurately map forest disturbances and their causes over a vast region remains limited known. This study investigated the effectiveness of six spectral indices (SIs) and two threshold methods (a forest-specific threshold and a common threshold) for detecting forest disturbances among four...

Supplementary Materials