31 Works

PTSD and complex PTSD in adolescence: discriminating factors in a population-based cross-sectional study

Ieva Daniunaite, Marylene Cloitre, Thanos Karatzias, Mark Shevlin, Siri Thoresen, Paulina Zelviene & Evaldas Kazlauskas
Background: Chronic and repeated trauma are well-established risk factors for complex posttraumatic stress disorder (CPTSD) in adult samples. Less is known about how trauma history and other factors contribute to the development of CPTSD in adolescence. Objective: The aim of this study was to assess the potential contribution of trauma history and social factors to CPTSD in adolescents. Method: In a cross-sectional community study of 1299 adolescents aged 12–16 years, PTSD (n = 97) and...

Wild birds as a reservoir of antimicrobial resistance (AMR) in the environment

Bimo Andrianus Djuwanto
Antimicrobial resistance (AMR) is one of the greatest public health threats and has been conceptualised as a slowly emerging disaster. Studies have suggested that wild birds contribute as a reservoir and dispersal route of AMR, and proximity to anthropogenic activity has been associated with higher prevalence of AMR. This study was conducted to determine the prevalence and diversity of extended-spectrum β-lactam (ESBL) resistant coliforms in wild bird populations in Scotland across a gradient of anthropogenic...

Illuminating the importance of craftsmanship in compassionate caring and facilitating its development in student nurses

Elizabeth Adamson
This thesis provides a critical reflection on my original contributions to knowledge in the field of nursing practice and nurse education over the last decade. Collectively my eight selected papers demonstrate an ongoing and incrementally developing conceptual approach. This culminates in the presentation, within my final capstone paper, of my original recombinant innovation. In this paper, application of the innovation is articulated through a compassionate craftsmanship relational model, which fuses multivalent ideas from the fields...

Diversity and digital leadership: Understanding experiences of workplace equality, diversity and inclusion

Melissa Highton
The aim of this research is to gain an understanding of the experiences and perceptions of workplace equality and diversity issues amongst digital leaders in higher education. The participants interviewed for this study are digital leaders working in universities in Scotland in 2019. The study provides a snapshot of data which has been interpreted to provide an understanding of the experiences and attitudes towards workplace equality, diversity and inclusion. It is the first study of...

Work on the move: mobilities of creativity and design ideation

Richard Firth
This thesis focuses on the development of original design ‘ideation’ processes (the formation of ideas or concepts) set within the context of both commercial museum and exhibition design contracts and product design pedagogic research. Taken together the published works that accompany this submission explore the impacts on productivity and creative problem solving when working away from a physical fixed studio or office-based environment. They also examine the significance of 'shared place' when working directly with...

Evolving legacy enterprise systems with microservices-based architecture in cloud environments

Safa Habibullah
Many legacy enterprise systems suffer from a number of common and critical problems. Such systems have often been implemented in the past with hardware and software technologies which are now out of date. Furthermore, they have often been modified in piecemeal so as to allow them to cope with changed requirements, and the need for new functionalities, which have come to light since their initial implementation. Thus, they are often ‘messy’ in their implementations and...

Exosomes as mediators of cell-to-cell communication in prostate cancer

Isla Bruce
Prostate cancer (PCa) is dependent on androgens for growth. Androgen deprivation therapy (ADT) curtails PCa progression, however this powerful selective pressure leads to aggressive, castrate resistant PCa. One castrate resistant prostate cancer subtype, neuroendocrine (NE) PCa, is characterised by increased abundance of NE cells. Transdifferentiation into androgen independent NE-like cells is thought to allow PCa epithelial cells to escape potent ADT, causing resistance. NE-like cells are thought to promote growth of surrounding tumour cells through...

Investigation of bus passenger discomfort and driver fatigue: An electroencephalography (EEG) approach

Benjamin Oladele Afuye
Efforts to improve urban bus transport systems’ comfort and increase user satisfaction have been made for many years across the globe. Increasing bus users and reducing car users has an economic benefit. Whenever the urban bus share is larger than 25%, there are journey time savings due to lower congestion levels on the network. A driver’s loss of alertness due to fatigue has been recognised to be one of the major factors responsible for road...

Scottish wild deer as a potential source of human pathogenic non-O157 Shiga toxin producing Escherichia coli (STEC)

Mairi Christine Mitchell
Shiga-toxin producing E. coli (STEC) are zoonotic pathogens, which release phage-encoded Shiga toxins (Stx). Stx subtypes stx2a and stx2d are associated with severe human disease. STEC O157 is the most common serotype in human disease although other pathogenic serotypes exist. Cattle, sheep and deer can carry STEC. A recent study found STEC O157 prevalence of 0.34 % (95 % CI = 0.02 – 6.30) in Scottish wild deer; however 69.5 % of faecal samples were...

SME ICT Marketing Impact: A New Conceptual Model

Justina Setkute & Simone Kurtzke

Enhancing storm surge resilience for coastal habitat: A framework to support sustainable development

Anitha Devi Karthik
More than 2.4 billion people live within 100 km of the sea coastline. Between 2016-2019 there has been a rising trend in tropical cyclone’s intensity and the frequency. Such cyclone events irrespective of their hurricane categorisation have persistently triggered coastal flooding such as storm surges of at least 7 ft (2 m). Over this period disaster losses from tropical cyclones have been estimated as US$ 343 billion, with over 3,333 deaths. A review of previous...

PTSD and complex PTSD in adolescence: discriminating factors in a population-based cross-sectional study

Ieva Daniunaite, Marylene Cloitre, Thanos Karatzias, Mark Shevlin, Siri Thoresen, Paulina Zelviene & Evaldas Kazlauskas
Background: Chronic and repeated trauma are well-established risk factors for complex posttraumatic stress disorder (CPTSD) in adult samples. Less is known about how trauma history and other factors contribute to the development of CPTSD in adolescence. Objective: The aim of this study was to assess the potential contribution of trauma history and social factors to CPTSD in adolescents. Method: In a cross-sectional community study of 1299 adolescents aged 12–16 years, PTSD (n = 97) and...

Change of the leader in an organisation and its impact on employee engagement

Glenda Gilkes
Current research highlights change of the leader as the new normal as organisations respond to austerity measures forced by changes in the global economy, shifting markets, mergers and acquisitions and rapid technological advancement. The Caribbean is not immune from these dynamics as many companies are foreign owned and led and as such, experience similar predicaments. Yet, there is a lack of understanding on how these changes affect employee engagement and more so, how employees should...

Exploration of interconnecting practices in Organizational Project Management (OPM) continuum

Murad Karimi
This study explores aspects of the Organizational Project Management (OPM) Continuum consisting of Project Management, Program Management and Portfolio Management domains of practice as well as the Project Management Office (PMO). The purpose of this research is to understand the OPM Continuum’s domains of practice and its interconnecting relationships; and to explore where in the process the interconnection is lost or the relationship is broken, subsequently closing the research loop by identifying possible improvement and...

Fatigue and the mind-body relation: a Lacanian exploration

Amanda Diserholt
This thesis explores the symptomatology of fatigue based on interviews conducted with seven people who are diagnosed with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. The thesis starts by examining how a biomedical view of fatigue — the dominant perspective in contemporary Western society — is underpinned by aporetic divisions, such as mind/body and individual/society. In pursuit of a more rigorous approach to fatigue, which explores rather than disavows division, the interview transcripts are analysed through the lens...

Characterisation of autophagy modulation by thiopurines in inflammatory bowel disease

Connan Dayton Masson
Background Inflammatory bowel disease (IBD), which includes Crohn’s disease (CD) and ulcerative colitis, are chronic diseases of the gastrointestinal tract. Genetic studies have identified strong association between genes involved in autophagy, ER-stress/unfolded protein response (UPR) and IBD. Stimulating autophagy may be beneficial for the treatment of IBD, and thiopurines, a class of drugs in clinical use for IBD, have been shown to induce autophagy. The aim of this study was to investigate the mechanism of...

Reframing knowledge brokering as a lever for dynamic capabilities: Early insights into a business process outsourcing company in Mauritius

Indravidoushi Chandraprema Dusoye
The purpose of this study is to expand the current conceptualisation of knowledge brokering and consider how it can be used as a lever for dynamic capabilities within the specific context of a business process outsourcing company based in Mauritius. In spite of the increasing phenomenon, there is a lack of understanding around knowledge brokering and no established strategic approach to deploy knowledge brokering process across the functional areas of organisations. Though practiced haphazardly in...

Design, synthesis and evaluation of novel and clinically used anti-cancer agents targeted intracellularly

Omar Mohammed
The development of drug resistance, notably multidrug resistance (MDR) and adverse side effects due to treatment with current anticancer drugs are considerable obstacles in cancer therapy and together with dose-limiting toxicity lead to therapeutic failure in the cancer clinic. The aim of this study is to design and deliver new anticancer agents selectively to the tumour site to increase efficacy and reduce toxic side effects to normal cells, thereby increasing the therapeutic index; this would...

Public charging infrastructure as the key enabler for electric mobility in Germany: The future electric vehicle charging point and the provision of parameters for a sustainable business model concept

Judith Karl
Electric mobility is enabling overall decarbonisation-targets by shaping a new, sustainable mobility. Related mobility behaviours are evolving rapidly and lead to fundamental changes within the respective infrastructure approaches. In doing so, public electrical charging is becoming a key prerequisite for the ramp-up of electric mobility. Yet there is still a lack of a nationwide public supply infrastructure in Germany because, at present, a profitable operation is not possible due to the volatile framework and low...

The effects of menstrual cycle phases on running repeated sprint ability

Samuele Di Nicola
Female participation in regular sport activities has increased in recent years, yet their representation in the sports and exercise science literature remains low. Therefore, an understanding of the effects different phases of the menstrual cycle (MC) have on exercise responses is important due to the practical and theoretical implications. The aim of this study was to compare performance, physiological and perceptual differences when performing a running repeated sprint ability (RSA) during the early-follicular (EF), and...

Evaluation of engagement with hyperlocal e-participation systems by citizens and representatives

Peter Cruickshank
This work is concerned with the information practices associated with hyperlocal representation. The findings derive from an evaluation of a portfolio of ten previously published papers covering the period 2010-2020. The main contributions are: (a) The development of the concept of hyperlocal representation as a domain with its own challenges; (b) The characterisation of hyperlocal representatives as stakeholders in the participation process; and (c) Expansion of the existence and nature of lurkers as passive participants...

Implementing urban freight policy measures: Using local transport policies to support urban consolidation centres

Emine Zehra Yurtkulu Akgün
This thesis presents an analysis of policymaking by local authorities in the context of urban freight transport (UFT). The aim of this study is to understand the impact of policy actions taken at the local level on the viability of urban consolidation centres (UCCs). UFT is a neglected topic in the case of local authorities; they often give very limited or no space to freight in their local transport plans. The main problem is that...

Mind the gap: Public equity as a financing solution for medium-sized enterprises and the influence of national culture

Lisa Paula Koch
Purpose: SMEs are the backbone of today’s economies. In order to be able to persist sustainably, sufficient access to finance is necessary. However, there is a financing gap for SMEs and traditional bank financing is not sustainable anymore due to ever more constraints. This research proposes the use of public equity to gain funding. However, the acceptance of public equity differs strongly between countries. The United Kingdom and Germany represent two polar extremes of financial...

Optimisation of monitoring using camera-traps and field evidence when identifying Eurasian otter Lutra lutra resting or breeding sites

Melanie Findlay
The Eurasian otter Lutra lutra and its resting places are protected by EU and UK legislation. Consultant ecologists must identify resting sites so they can be protected during developments. Currently, consultants usually use field-signs, but radio-telemetry studies indicate this may be unreliable. Camera-traps could be used to identify resting sites within the consultancy industry. This research aims to improve field-sign and camera-trap survey methods to identify otter resting sites. Firstly, camera-trap methodology is considered. Arrays...

The future is unwritten. E-publishing in small nations of Europe: A comparative approach to policy frameworks and small business strategies

Anna Friederike Maria Elise Klamet
Digitisation, together with the spread of the internet, has initiated a transition phase in publishing. This transition not only affects the production process but also the way of communication, the product itself and its distribution. International corporations have entered the digital marketplace and transformed the whole publishing network. Research has shown from an industry perspective that digital disruption forces established firms to adapt in order to capitalise on new opportunities digital technologies offer and to...

Registration Year

  • 2021
    31

Resource Types

  • Text
    31

Affiliations

  • Edinburgh Napier University
    31
  • Norwegian Centre for Violence and Traumatic Stress Studies
    2
  • University of Oslo
    2
  • University of Ulster
    2
  • National University of Ireland, Galway
    1
  • Technological University Dublin
    1